BRPI0807907A2 - co-cristais e composições farmacêuticas compreendendo os mesmos. - Google Patents

co-cristais e composições farmacêuticas compreendendo os mesmos.

Info

Publication number
BRPI0807907A2
BRPI0807907A2 BRPI0807907A BRPI0807907A BRPI0807907A2 BR PI0807907 A2 BRPI0807907 A2 BR PI0807907A2 BR PI0807907 A BRPI0807907 A BR PI0807907A BR PI0807907 A BRPI0807907 A BR PI0807907A BR PI0807907 A2 BRPI0807907 A2 BR PI0807907A2
Authority
BR
Brazil
Prior art keywords
cocrystals
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Application number
BRPI0807907A
Other languages
English (en)
Inventor
Rao Bhisetti Govinda
Kadiyala Irina
Stavropolus Kathy
Connely Patrick
Rose Peter
Johnston Steve
Jurkauskas Valdas
Zhang Yuegang
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of BRPI0807907A2 publication Critical patent/BRPI0807907A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
BRPI0807907A 2007-02-27 2008-02-27 co-cristais e composições farmacêuticas compreendendo os mesmos. BRPI0807907A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90358707P 2007-02-27 2007-02-27
PCT/US2008/002568 WO2008106151A2 (en) 2007-02-27 2008-02-27 Co-crystals and pharmaceutical compositions comprising the same

Publications (1)

Publication Number Publication Date
BRPI0807907A2 true BRPI0807907A2 (pt) 2017-05-16

Family

ID=39672669

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0807907A BRPI0807907A2 (pt) 2007-02-27 2008-02-27 co-cristais e composições farmacêuticas compreendendo os mesmos.

Country Status (28)

Country Link
US (1) US8759353B2 (pt)
EP (3) EP2463285A1 (pt)
JP (1) JP2010519330A (pt)
KR (1) KR20090115970A (pt)
CN (1) CN101687856A (pt)
AP (1) AP2009004960A0 (pt)
AR (1) AR065498A1 (pt)
AT (1) ATE542815T1 (pt)
AU (1) AU2008219607B2 (pt)
BR (1) BRPI0807907A2 (pt)
CA (1) CA2679312A1 (pt)
CO (1) CO6220963A2 (pt)
CY (1) CY1112865T1 (pt)
DK (1) DK2114924T3 (pt)
EA (1) EA200970806A1 (pt)
EC (1) ECSP099600A (pt)
ES (1) ES2379905T3 (pt)
GE (1) GEP20125645B (pt)
HR (1) HRP20120330T1 (pt)
IL (1) IL200616A0 (pt)
MX (1) MX2009009182A (pt)
NZ (1) NZ579442A (pt)
PL (1) PL2114924T3 (pt)
PT (1) PT2114924E (pt)
RS (1) RS52306B (pt)
SI (1) SI2114924T1 (pt)
TW (1) TW200846343A (pt)
WO (1) WO2008106151A2 (pt)

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US8399615B2 (en) 2005-08-19 2013-03-19 Vertex Pharmaceuticals Incorporated Processes and intermediates
CA2643688A1 (en) * 2006-02-27 2007-08-30 Vertex Pharmaceuticals Incorporated Co-crystals and pharmaceutical compositions comprising the same
AU2009288200A1 (en) * 2008-09-03 2010-03-11 Vertex Pharmaceuticals Incorporated Co-crystals and pharmaceutical formulations comprising the same
EP2396028A2 (en) 2009-02-12 2011-12-21 Vertex Pharmceuticals Incorporated Hcv combination therapies comprising pegylated interferon, ribavirin and telaprevir
WO2011054741A2 (en) * 2009-11-06 2011-05-12 Basf Se Crystalline complexes of 4-hydroxy benzoic acid and selected pesticides
TW201130502A (en) 2010-01-29 2011-09-16 Vertex Pharma Therapies for treating hepatitis C virus infection
WO2011112922A2 (en) * 2010-03-11 2011-09-15 Vertex Pharmaceuticals Incorporated Co-crystals and pharmaceutical formulations comprising the same
WO2011156545A1 (en) 2010-06-09 2011-12-15 Vertex Pharmaceuticals Incorporated Viral dynamic model for hcv combination therapy
WO2012009503A1 (en) 2010-07-14 2012-01-19 Vertex Pharmaceuticals Incorporated Palatable pharmaceutical composition comprising vx-950
US20140308242A1 (en) 2010-10-21 2014-10-16 Vertex Pharmaceuticals Incorporated Biomarkers for hcv infected patients
WO2012109646A1 (en) 2011-02-11 2012-08-16 Vertex Pharmaceuticals Incorporated Treatment of hcv in hiv infection patients
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SE1450130A1 (sv) 2011-10-21 2014-05-07 Abbvie Inc Förfaranden för att behandla hcv innefattande minst två direktverkande antivirala agenser, ribavirin men inte interferon
EP2583680A3 (en) 2011-10-21 2013-06-12 Abbvie Inc. Mono (PSI-7977) or combination treatment of DAAs for use in treating HCV
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WO2013116339A1 (en) 2012-01-31 2013-08-08 Vertex Pharmaceuticals Incorporated High potency formulations of vx-950
WO2014015217A1 (en) 2012-07-19 2014-01-23 Vertex Pharmaceuticals Incorporated Biomarkers for hcv infected patients
WO2014033617A1 (en) * 2012-08-31 2014-03-06 Novartis Ag 2'-ethynyl nucleoside derivatives for treatment of viral infections
ITMI20131839A1 (it) * 2013-11-06 2015-05-07 Dipharma Francis Srl Co-cristallo di un farmaco antidepressivo
CN103819379A (zh) * 2014-02-18 2014-05-28 中国科学院上海药物研究所 维生素d3的胆甾烷醇共结晶及其制备方法和应用
CN105696066B (zh) * 2015-10-26 2018-07-03 西北大学 一种压片法制备共晶的方法
EA201892448A1 (ru) 2016-04-28 2019-06-28 Эмори Юниверсити Алкинсодержащие нуклеотидные и нуклеозидные терапевтические композиции и связанные с ними способы применения
CN113295723B (zh) * 2021-07-27 2021-09-28 西南石油大学 一种岩石中粘土矿物的分子模拟表征方法

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AU2008219607A1 (en) 2008-09-04
KR20090115970A (ko) 2009-11-10
CO6220963A2 (es) 2010-11-19
ATE542815T1 (de) 2012-02-15
NZ579442A (en) 2012-02-24
AR065498A1 (es) 2009-06-10
CY1112865T1 (el) 2016-04-13
AP2009004960A0 (en) 2009-08-31
US20110059987A1 (en) 2011-03-10
DK2114924T3 (da) 2012-04-10
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EA200970806A1 (ru) 2010-08-30
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CA2679312A1 (en) 2008-09-04
EP2463285A1 (en) 2012-06-13
TW200846343A (en) 2008-12-01
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RS52306B (sr) 2012-12-31
MX2009009182A (es) 2009-09-04
AU2008219607B2 (en) 2013-09-12
US8759353B2 (en) 2014-06-24
ECSP099600A (es) 2009-09-29
PT2114924E (pt) 2012-04-03
HRP20120330T1 (hr) 2012-05-31
EP2114924A2 (en) 2009-11-11
GEP20125645B (en) 2012-09-25
EP2463284A1 (en) 2012-06-13
CN101687856A (zh) 2010-03-31
PL2114924T3 (pl) 2012-07-31

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