BRPI0807952A2 - Sistemas de hipermutação somática - Google Patents
Sistemas de hipermutação somáticaInfo
- Publication number
- BRPI0807952A2 BRPI0807952A2 BRPI0807952-8A2A BRPI0807952A BRPI0807952A2 BR PI0807952 A2 BRPI0807952 A2 BR PI0807952A2 BR PI0807952 A BRPI0807952 A BR PI0807952A BR PI0807952 A2 BRPI0807952 A2 BR PI0807952A2
- Authority
- BR
- Brazil
- Prior art keywords
- somatic hypermutation
- systems
- hypermutation systems
- somatic
- hypermutation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90241407P | 2007-02-20 | 2007-02-20 | |
| US90462207P | 2007-03-01 | 2007-03-01 | |
| US99597007P | 2007-09-28 | 2007-09-28 | |
| US2012408P | 2008-01-09 | 2008-01-09 | |
| PCT/US2008/002397 WO2008103475A1 (en) | 2007-02-20 | 2008-02-20 | Somatic hypermutation systems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0807952A2 true BRPI0807952A2 (pt) | 2014-06-10 |
Family
ID=39710412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0807952-8A2A BRPI0807952A2 (pt) | 2007-02-20 | 2008-02-20 | Sistemas de hipermutação somática |
Country Status (8)
| Country | Link |
|---|---|
| US (7) | US20090075378A1 (pt) |
| EP (2) | EP2126105A4 (pt) |
| JP (3) | JP5675109B2 (pt) |
| AU (1) | AU2008218925A1 (pt) |
| BR (1) | BRPI0807952A2 (pt) |
| CA (1) | CA2678451A1 (pt) |
| NZ (1) | NZ579010A (pt) |
| WO (2) | WO2008103474A1 (pt) |
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-
2008
- 2008-02-20 US US12/070,905 patent/US20090075378A1/en not_active Abandoned
- 2008-02-20 EP EP08725985A patent/EP2126105A4/en not_active Withdrawn
- 2008-02-20 JP JP2009550935A patent/JP5675109B2/ja active Active
- 2008-02-20 US US12/070,904 patent/US8603950B2/en active Active
- 2008-02-20 JP JP2009550936A patent/JP2010520748A/ja active Pending
- 2008-02-20 BR BRPI0807952-8A2A patent/BRPI0807952A2/pt not_active Application Discontinuation
- 2008-02-20 WO PCT/US2008/002396 patent/WO2008103474A1/en not_active Ceased
- 2008-02-20 WO PCT/US2008/002397 patent/WO2008103475A1/en not_active Ceased
- 2008-02-20 NZ NZ579010A patent/NZ579010A/en unknown
- 2008-02-20 CA CA002678451A patent/CA2678451A1/en not_active Abandoned
- 2008-02-20 EP EP08725984A patent/EP2126087A4/en not_active Ceased
- 2008-02-20 AU AU2008218925A patent/AU2008218925A1/en not_active Abandoned
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2010
- 2010-12-17 US US12/972,328 patent/US20110183855A1/en not_active Abandoned
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2011
- 2011-05-17 US US13/109,106 patent/US8685897B2/en active Active
- 2011-10-12 US US13/272,065 patent/US20120028301A1/en not_active Abandoned
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2013
- 2013-04-26 JP JP2013094218A patent/JP2013220103A/ja active Pending
- 2013-10-11 US US14/052,451 patent/US9637556B2/en active Active
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2014
- 2014-02-14 US US14/181,096 patent/US9260533B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9637556B2 (en) | 2017-05-02 |
| EP2126105A4 (en) | 2010-11-03 |
| WO2008103475A1 (en) | 2008-08-28 |
| AU2008218925A1 (en) | 2008-08-28 |
| US20140170705A1 (en) | 2014-06-19 |
| US8685897B2 (en) | 2014-04-01 |
| US20110287485A1 (en) | 2011-11-24 |
| JP5675109B2 (ja) | 2015-02-25 |
| WO2008103474A1 (en) | 2008-08-28 |
| CA2678451A1 (en) | 2008-08-28 |
| NZ579010A (en) | 2012-03-30 |
| US8603950B2 (en) | 2013-12-10 |
| US20090093024A1 (en) | 2009-04-09 |
| US20140094392A1 (en) | 2014-04-03 |
| JP2010518859A (ja) | 2010-06-03 |
| EP2126087A1 (en) | 2009-12-02 |
| US20110183855A1 (en) | 2011-07-28 |
| EP2126087A4 (en) | 2010-10-27 |
| JP2013220103A (ja) | 2013-10-28 |
| US20120028301A1 (en) | 2012-02-02 |
| US9260533B2 (en) | 2016-02-16 |
| JP2010520748A (ja) | 2010-06-17 |
| EP2126105A1 (en) | 2009-12-02 |
| US20090075378A1 (en) | 2009-03-19 |
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