BRPI0819273A2 - Produção de ácido dicarboxílico em eucariontes - Google Patents
Produção de ácido dicarboxílico em eucariontesInfo
- Publication number
- BRPI0819273A2 BRPI0819273A2 BRPI0819273-1A2A BRPI0819273A BRPI0819273A2 BR PI0819273 A2 BRPI0819273 A2 BR PI0819273A2 BR PI0819273 A BRPI0819273 A BR PI0819273A BR PI0819273 A2 BRPI0819273 A2 BR PI0819273A2
- Authority
- BR
- Brazil
- Prior art keywords
- eukariontes
- dicarboxylic acid
- acid production
- eukaryotic cell
- present
- Prior art date
Links
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 title 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 abstract 4
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 2
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 2
- 239000001384 succinic acid Substances 0.000 abstract 2
- 241000233866 Fungi Species 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 102000019259 Succinate Dehydrogenase Human genes 0.000 abstract 1
- 108010012901 Succinate Dehydrogenase Proteins 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 239000001530 fumaric acid Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fuel Cell (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07121113 | 2007-11-20 | ||
| EP07121120 | 2007-11-20 | ||
| EP07121120.5 | 2007-11-20 | ||
| EP07121117.1 | 2007-11-20 | ||
| EP07121117 | 2007-11-20 | ||
| EP07121113.0 | 2007-11-20 | ||
| EP08156960.0 | 2008-05-27 | ||
| EP08156959 | 2008-05-27 | ||
| EP08156960 | 2008-05-27 | ||
| EP08156961 | 2008-05-27 | ||
| PCT/EP2008/065588 WO2009065780A1 (en) | 2007-11-20 | 2008-11-14 | Dicarboxylic acid production in eukaryotes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0819273A2 true BRPI0819273A2 (pt) | 2014-10-14 |
| BRPI0819273B1 BRPI0819273B1 (pt) | 2022-05-17 |
| BRPI0819273B8 BRPI0819273B8 (pt) | 2022-07-19 |
Family
ID=40268299
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0819275A BRPI0819275B8 (pt) | 2007-11-20 | 2008-11-14 | Célula eucariótica recombinante produtora de ácido succínico e processo para a preparação de ácido succínico |
| BRPI0819273A BRPI0819273B8 (pt) | 2007-11-20 | 2008-11-14 | Célula microbiana eucariótica recombinante e processo para a preparação de um ácido dicarboxílico |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0819275A BRPI0819275B8 (pt) | 2007-11-20 | 2008-11-14 | Célula eucariótica recombinante produtora de ácido succínico e processo para a preparação de ácido succínico |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20120165569A1 (pt) |
| EP (3) | EP2687602A1 (pt) |
| JP (2) | JP5641938B2 (pt) |
| CN (3) | CN101903522B (pt) |
| AT (1) | ATE555203T1 (pt) |
| BR (2) | BRPI0819275B8 (pt) |
| CA (2) | CA2875319A1 (pt) |
| EA (1) | EA032726B1 (pt) |
| ES (2) | ES2522622T3 (pt) |
| WO (2) | WO2009065778A1 (pt) |
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|---|---|---|---|---|
| EP2158323A4 (en) * | 2007-05-18 | 2011-06-22 | Microbia Prec Engineering Inc | PRODUCTION OF ORGANIC ACID BY PILZ CELLS |
| WO2009065778A1 (en) * | 2007-11-20 | 2009-05-28 | Dsm Ip Assets B.V. | Succinic acid production in a eukaryotic cell |
| US20110104771A1 (en) * | 2008-02-15 | 2011-05-05 | Rene Verwall | Process for the production of a dicarboxylic acid |
| PL2297297T3 (pl) | 2008-07-08 | 2017-08-31 | Dsm Ip Assets B.V. | Wytwarzanie kwasu bursztynowego przez fermentację w niskim pH |
| RU2422526C2 (ru) * | 2009-01-30 | 2011-06-27 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов (ФГУП ГосНИИгенетика) | СПОСОБ ПОЛУЧЕНИЯ ЯНТАРНОЙ КИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ ДРОЖЖЕЙ, ПРИНАДЛЕЖАЩИХ К РОДУ Yarrowia |
| WO2010118932A1 (en) * | 2009-04-15 | 2010-10-21 | Dsm Ip Assets B.V. | Dicarboxylic acid production process |
| UA108853C2 (uk) | 2009-07-10 | 2015-06-25 | Спосіб ферментації галактози | |
| EP3282017A1 (en) | 2009-08-27 | 2018-02-14 | DSM IP Assets B.V. | Dicarboxylic acid fermentation process |
| BR112012004594A2 (pt) | 2009-09-01 | 2016-06-21 | Novozymes Inc | célula hospedeira fúngica filamentosa, e, método para produzir um ácido dicarboxílico |
| WO2011064151A1 (en) | 2009-11-24 | 2011-06-03 | Dsm Ip Assets B.V. | Process for the crystallization of succinic acid |
| JP2011120508A (ja) * | 2009-12-09 | 2011-06-23 | Oji Paper Co Ltd | コハク酸を製造する方法 |
| JP2013516180A (ja) | 2009-12-31 | 2013-05-13 | ミリアント・コーポレイション | コハク酸アンモニウムを含有する発酵ブロスからのコハク酸の精製 |
| JP5857954B2 (ja) | 2010-03-09 | 2016-02-10 | 三菱化学株式会社 | コハク酸の製造方法 |
| EP2371802A1 (en) | 2010-03-30 | 2011-10-05 | DSM IP Assets B.V. | Process for the crystallization of succinic acid |
| CA2800343A1 (en) | 2010-04-21 | 2011-10-27 | Dsm Ip Assets B.V. | Process for the production of cells which are capable of converting arabinose |
| WO2011153317A1 (en) | 2010-06-04 | 2011-12-08 | Novozymes, Inc. | C4 dicarboxylic acid production in filamentous fungi |
| EP2582716A1 (en) | 2010-06-21 | 2013-04-24 | Novozymes, Inc. | Aspergillus aculeatus derived polypeptides having c4-dicarboxylic acid transporter activity and polynucleotides encoding same |
| IN2013CN00459A (pt) | 2010-06-21 | 2015-07-03 | Novozymes Inc | |
| US9187772B2 (en) * | 2010-09-01 | 2015-11-17 | University Of Florida Research Foundation, Inc. | L-malate production by metabolically engineered escherichia coli |
| US20130171704A1 (en) | 2010-09-24 | 2013-07-04 | Roquette Freres Sa | Dicarboxylic acid production process |
| CN103502429B (zh) | 2010-10-28 | 2018-07-17 | 道达尔研究技术弗吕股份有限公司 | 使用红曲霉来生产聚乳酸的方法 |
| EP2495304A1 (en) | 2010-12-03 | 2012-09-05 | DSM IP Assets B.V. | Dicarboxylic acid production in a yeast cell |
| CA2825525A1 (en) | 2011-01-25 | 2012-08-02 | Jeanette M. HURYTA | Compositions and methods for succinate production |
| WO2012118848A1 (en) | 2011-02-28 | 2012-09-07 | Novozymes, Inc. | Microorganism for c4-dicarboxylic acid production |
| BR112013033760B1 (pt) | 2011-07-01 | 2020-10-27 | Dsm Ip Assets B.V. | processo de produção de ácido dicarboxílico |
| CN103917649A (zh) | 2011-08-19 | 2014-07-09 | 诺维信股份有限公司 | 用于生产c4-二羧酸的重组微生物 |
| CN102559518B (zh) * | 2011-12-20 | 2013-10-16 | 江南大学 | 一种高产延胡索酸米根霉及其应用 |
| EP2807262A4 (en) * | 2012-01-25 | 2015-12-30 | Bioamber Internat S A R L | PROCESS FOR SUCCINATE MANUFACTURE |
| FR2987678B1 (fr) | 2012-03-02 | 2016-04-15 | Roquette Freres | Methode de mesure de la stabilite thermique d'un acide succinique cristallin destine a la fabrication de polymeres |
| FR2988733B1 (fr) | 2012-03-27 | 2016-02-05 | Carbios | Microorganisme recombinant |
| KR101464656B1 (ko) * | 2012-06-15 | 2014-12-02 | 한국생명공학연구원 | 발효산물 고생성능을 가지는 변이 미생물 및 이를 이용한 발효산물의 제조방법 |
| WO2014018755A1 (en) | 2012-07-25 | 2014-01-30 | Cargill Incorporated | Yeast cells having nadp(h)-dependent reductive tca pathway from pyruvate to succinate |
| US9850507B2 (en) | 2012-07-25 | 2017-12-26 | Cargill, Incorporated | Yeast cells having reductive TCA pathway from pyruvate to succinate and overexpressing an exogenous NAD(P)+ transhydrogenase enzyme |
| US20150211024A1 (en) * | 2012-08-28 | 2015-07-30 | Braskem S.A. | Methods for production of a terpene and a co-product |
| CN104812889B (zh) * | 2012-09-14 | 2018-08-28 | 麦兰特公司 | 通过在低ph下发酵产生有机酸 |
| US9809833B2 (en) | 2012-09-20 | 2017-11-07 | Bioamber Inc. | Pathways to adipate semialdehyde and other organic products |
| EP2964687A2 (en) | 2013-03-08 | 2016-01-13 | DSM IP Assets B.V. | Polyester |
| WO2015007902A1 (en) * | 2013-07-18 | 2015-01-22 | Dsm Ip Assets B.V. | Fermentation process |
| CN105814198A (zh) * | 2013-12-12 | 2016-07-27 | 帝斯曼知识产权资产管理有限公司 | 延胡索酸还原酶 |
| JP6620373B2 (ja) * | 2014-06-30 | 2019-12-18 | Ｊｍｔｃエンザイム株式会社 | 形質転換体およびその製造方法、ならびに炭素数４のジカルボン酸の製造方法 |
| US9882151B2 (en) | 2014-11-14 | 2018-01-30 | Universal Display Corporation | Organic electroluminescent materials and devices |
| PL3227256T3 (pl) | 2014-12-02 | 2019-09-30 | Roquette Frères | Sposób wytwarzania kwasu bursztynowego z bulionu fermentacyjnego z zastosowaniem nanoflltracji do oczyszczania zawracanego do obiegu ługu macierzystego |
| EP3067378A1 (en) | 2015-03-11 | 2016-09-14 | DSM IP Assets B.V. | Polyester |
| CA2985231A1 (en) | 2015-06-04 | 2016-12-08 | Bioamber Inc. | Biobased production of functionalized alpha-substituted acrylates and c4-dicarboxylates |
| EP3394251B1 (en) * | 2015-12-23 | 2022-12-21 | DSM IP Assets B.V. | Host cells for dicarboxylic acid production |
| JP2017121184A (ja) * | 2016-01-04 | 2017-07-13 | 花王株式会社 | 変異リゾプス属菌 |
| CN116286420A (zh) | 2016-07-13 | 2023-06-23 | 帝斯曼知识产权资产管理有限公司 | 苹果酸脱氢酶 |
| DE102016115425A1 (de) * | 2016-08-19 | 2018-02-22 | Jacobs University Bremen Ggmbh | Gentechnisch veränderte Hefe zur Fermentation von Glycerol |
| CN110914334A (zh) | 2017-05-18 | 2020-03-24 | 阿凡田知识中心有限公司 | 聚酯共聚物 |
| US11306179B2 (en) | 2017-05-18 | 2022-04-19 | Avantium Knowledge Centre B.V. | Polyester copolymer |
| US11608488B2 (en) * | 2017-07-11 | 2023-03-21 | Adisseo France S.A.S. | Enhanced metabolite-producing yeast |
| WO2019226972A1 (en) * | 2018-05-25 | 2019-11-28 | Danisco Us Inc | Overexpression of fumarate reductase results in an increased fermentation rate in yeast |
| KR102129379B1 (ko) * | 2018-10-10 | 2020-07-02 | 한국과학기술원 | 고활성의 말산 탈수소효소가 도입된 숙신산 생성용 변이 미생물 및 이를 이용한 숙신산 제조방법 |
| EP3883985A1 (en) | 2018-11-22 | 2021-09-29 | Avantium Knowledge Centre B.V. | Process for the production of one or more polyester copolymers, method for the preparation of one or more oligomers, oligomer composition and polyester copolymer |
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| CN104812889B (zh) | 2012-09-14 | 2018-08-28 | 麦兰特公司 | 通过在低ph下发酵产生有机酸 |
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2008
- 2008-11-14 WO PCT/EP2008/065583 patent/WO2009065778A1/en not_active Ceased
- 2008-11-14 US US12/743,106 patent/US20120165569A1/en not_active Abandoned
- 2008-11-14 CA CA2875319A patent/CA2875319A1/en not_active Abandoned
- 2008-11-14 CN CN200880117105.8A patent/CN101903522B/zh active Active
- 2008-11-14 EA EA201000837A patent/EA032726B1/ru not_active IP Right Cessation
- 2008-11-14 ES ES08851178.7T patent/ES2522622T3/es active Active
- 2008-11-14 EP EP13170415.7A patent/EP2687602A1/en not_active Withdrawn
- 2008-11-14 CA CA2704654A patent/CA2704654C/en active Active
- 2008-11-14 BR BRPI0819275A patent/BRPI0819275B8/pt active IP Right Grant
- 2008-11-14 EP EP08851601A patent/EP2220233B1/en active Active
- 2008-11-14 BR BRPI0819273A patent/BRPI0819273B8/pt active IP Right Grant
- 2008-11-14 WO PCT/EP2008/065588 patent/WO2009065780A1/en not_active Ceased
- 2008-11-14 EP EP08851178.7A patent/EP2220232B1/en active Active
- 2008-11-14 JP JP2010533596A patent/JP5641938B2/ja active Active
- 2008-11-14 CN CN201510186003.3A patent/CN104818224A/zh active Pending
- 2008-11-14 ES ES08851601T patent/ES2383473T3/es active Active
- 2008-11-14 US US12/743,927 patent/US9340804B2/en active Active
- 2008-11-14 CN CN200880117129.3A patent/CN101978063B/zh active Active
- 2008-11-14 AT AT08851601T patent/ATE555203T1/de active
-
2013
- 2013-10-02 US US14/044,722 patent/US9689005B2/en active Active
-
2014
- 2014-07-25 JP JP2014151882A patent/JP2014236739A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014236739A (ja) | 2014-12-18 |
| CN101978063B (zh) | 2018-10-16 |
| BRPI0819275B1 (pt) | 2022-05-17 |
| CA2704654C (en) | 2015-02-10 |
| BRPI0819275B8 (pt) | 2022-07-19 |
| US20120165569A1 (en) | 2012-06-28 |
| EP2687602A1 (en) | 2014-01-22 |
| EP2220233A1 (en) | 2010-08-25 |
| ES2383473T3 (es) | 2012-06-21 |
| WO2009065778A1 (en) | 2009-05-28 |
| US9689005B2 (en) | 2017-06-27 |
| JP2011502524A (ja) | 2011-01-27 |
| BRPI0819275A2 (pt) | 2014-10-14 |
| CN101903522A (zh) | 2010-12-01 |
| BRPI0819273B1 (pt) | 2022-05-17 |
| WO2009065780A1 (en) | 2009-05-28 |
| CN101978063A (zh) | 2011-02-16 |
| CA2704654A1 (en) | 2009-05-28 |
| US20110081694A1 (en) | 2011-04-07 |
| EP2220233B1 (en) | 2012-04-25 |
| EA032726B1 (ru) | 2019-07-31 |
| EP2220232A1 (en) | 2010-08-25 |
| EA201000837A1 (ru) | 2010-12-30 |
| US9340804B2 (en) | 2016-05-17 |
| BRPI0819273B8 (pt) | 2022-07-19 |
| ATE555203T1 (de) | 2012-05-15 |
| JP5641938B2 (ja) | 2014-12-17 |
| CA2875319A1 (en) | 2009-05-28 |
| ES2522622T3 (es) | 2014-11-17 |
| US20140031587A1 (en) | 2014-01-30 |
| CN104818224A (zh) | 2015-08-05 |
| CN101903522B (zh) | 2015-08-05 |
| EP2220232B1 (en) | 2014-09-03 |
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