BRPI0908756A2 - Uso combinado de derivado do colestanol - Google Patents

Uso combinado de derivado do colestanol

Info

Publication number: BRPI0908756A2
Authority: BR; Brazil
Prior art keywords: combined use; cholestanol derivative; cholestanol; derivative; combined
Prior art date: 2008-03-05

Application number

BRPI0908756-7A

Other languages

English (en)

Inventor

Shin Yazawa

Toyo Nishimura

Takayuki Asao

Original Assignee

Otsuka Pharma Co Ltd

Univ Gunma Nat Univ Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-03-05

Filing date

2009-03-04

Publication date

2015-07-21

2009-03-04 Application filed by Otsuka Pharma Co Ltd, Univ Gunma Nat Univ Corp filed Critical Otsuka Pharma Co Ltd

2015-07-21 Publication of BRPI0908756A2 publication Critical patent/BRPI0908756A2/pt

Links

QYIXCDOBOSTCEI-QCYZZNICSA-N (5alpha)-cholestan-3beta-ol Chemical class C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CCCC(C)C)[C@@]2(C)CC1 QYIXCDOBOSTCEI-QCYZZNICSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/664—Amides of phosphorus acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J17/005—Glycosides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Inorganic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Dispersion Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BRPI0908756-7A 2008-03-05 2009-03-04 Uso combinado de derivado do colestanol BRPI0908756A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2008055284		2008-03-05
PCT/JP2009/000985 WO2009110235A1 (ja)	2008-03-05	2009-03-04	コレスタノール誘導体の併用用途

Publications (1)

Publication Number	Publication Date
BRPI0908756A2 true BRPI0908756A2 (pt)	2015-07-21

Family

ID=41055800

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
BRPI0908756-7A BRPI0908756A2 (pt)	2008-03-05	2009-03-04	Uso combinado de derivado do colestanol
BRPI0924525A BRPI0924525A2 (pt)	2008-03-05	2009-09-03	"derivativos de colestanol para uso combinado"

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
BRPI0924525A BRPI0924525A2 (pt)	2008-03-05	2009-09-03	"derivativos de colestanol para uso combinado"

Country Status (26)

Country	Link
US (6)	US8088744B2 (pt)
EP (1)	EP2251014B8 (pt)
JP (1)	JP5336466B2 (pt)
KR (1)	KR20100120674A (pt)
CN (2)	CN101678037B (pt)
AR (1)	AR070857A1 (pt)
AU (1)	AU2009220699C1 (pt)
BR (2)	BRPI0908756A2 (pt)
CA (1)	CA2717135A1 (pt)
CO (2)	CO6311080A2 (pt)
CY (1)	CY1115217T1 (pt)
DK (1)	DK2251014T3 (pt)
ES (1)	ES2437640T3 (pt)
HR (2)	HRP20140154T1 (pt)
IL (1)	IL207874A (pt)
MX (1)	MX2010009794A (pt)
NZ (2)	NZ587729A (pt)
PL (1)	PL2251014T3 (pt)
PT (1)	PT2251014E (pt)
RU (1)	RU2492865C2 (pt)
SG (2)	SG188805A1 (pt)
SI (1)	SI2251014T1 (pt)
TW (1)	TWI492759B (pt)
UA (2)	UA101831C2 (pt)
WO (1)	WO2009110235A1 (pt)
ZA (1)	ZA201006228B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ589967A (en) *	2004-01-14	2012-07-27	Gilead Sciences Inc	Lipid-based dispersions useful for drug delivery
ES2534800T3 (es) *	2009-03-04	2015-04-29	Otsuka Pharmaceutical Co., Ltd.	Derivado de colestanol para uso combinado
JP5480241B2 (ja) *	2009-03-04	2014-04-23	大塚製薬株式会社	コレスタノール誘導体の併用用途
WO2013179310A1 (en) *	2012-05-31	2013-12-05	Mylan Laboratories Limited	Stable aqueous compositions of pemetrexed
CN119855598A (zh) *	2022-07-20	2025-04-18	约翰内斯堡威特沃特斯兰德大学	作为癌症疗法新辅助剂或辅助剂的2-羟丙基-β-环糊精

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5782310A (en)	1980-11-11	1982-05-22	Tanabe Seiyaku Co Ltd	Production of liposome preparation
JPS6012127A (ja)	1983-06-30	1985-01-22	Dai Ichi Seiyaku Co Ltd	リポソ−ムの製法
JPS6058915A (ja)	1983-09-12	1985-04-05	Fujisawa Pharmaceut Co Ltd	薬物含有脂質小胞体製剤
JPH0610131B2 (ja)	1987-10-30	1994-02-09	テルモ株式会社	リポソームの製法
JPH01167218A (ja)	1987-12-22	1989-06-30	Sumitomo Electric Ind Ltd	超電導薄膜の作製方法
JPH082780B2 (ja)	1990-05-28	1996-01-17	テルモ株式会社	リポソームの製法
JP3831958B2 (ja)	1995-09-20	2006-10-11	日本油脂株式会社	リポソーム用混合脂質及びリポソーム分散液
JP4105258B2 (ja) *	1997-08-19	2008-06-25	大塚製薬株式会社	コレスタノール化合物及びこれを含有する医薬
JP4351314B2 (ja)	1998-12-24	2009-10-28	大塚製薬株式会社	コレスタノール化合物及びこれを含有する医薬
EE200200565A (et) *	2000-03-31	2004-06-15	Angiogene Pharmaceuticals Ltd.	Vaskulaarse kahjustava toimega kombinatsioonravi
EP1647277A4 (en) *	2003-07-17	2011-09-21	Otsuka Pharma Co Ltd	LIPOSOME CONTAINING GLYCOSIDE
ZA200604579B (en) *	2003-12-08	2007-10-31	Univ Arizona	Synergistic anti-cancer compositions
EP1753512B1 (en)	2004-05-28	2008-07-09	Nycomed GmbH	Tetrahydropyridothiophenes
TWI373473B (en) *	2005-09-02	2012-10-01	Otsuka Pharma Co Ltd	Anticancer agent

2009
- 2009-03-03 TW TW098106869A patent/TWI492759B/zh not_active IP Right Cessation
- 2009-03-04 WO PCT/JP2009/000985 patent/WO2009110235A1/ja not_active Ceased
- 2009-03-04 ES ES09718009.5T patent/ES2437640T3/es active Active
- 2009-03-04 HR HRP20140154AT patent/HRP20140154T1/hr unknown
- 2009-03-04 EP EP09718009.5A patent/EP2251014B8/en not_active Not-in-force
- 2009-03-04 CA CA2717135A patent/CA2717135A1/en not_active Abandoned
- 2009-03-04 PL PL09718009T patent/PL2251014T3/pl unknown
- 2009-03-04 RU RU2010140611/15A patent/RU2492865C2/ru not_active IP Right Cessation
- 2009-03-04 SI SI200930808T patent/SI2251014T1/sl unknown
- 2009-03-04 KR KR1020107019395A patent/KR20100120674A/ko not_active Abandoned
- 2009-03-04 NZ NZ587729A patent/NZ587729A/en unknown
- 2009-03-04 JP JP2010501802A patent/JP5336466B2/ja not_active Expired - Fee Related
- 2009-03-04 CN CN2009800001938A patent/CN101678037B/zh not_active Expired - Fee Related
- 2009-03-04 AU AU2009220699A patent/AU2009220699C1/en not_active Ceased
- 2009-03-04 PT PT97180095T patent/PT2251014E/pt unknown
- 2009-03-04 DK DK09718009.5T patent/DK2251014T3/da active
- 2009-03-04 AR ARP090100765A patent/AR070857A1/es unknown
- 2009-03-04 SG SG2013013800A patent/SG188805A1/en unknown
- 2009-03-04 BR BRPI0908756-7A patent/BRPI0908756A2/pt not_active IP Right Cessation
- 2009-03-04 NZ NZ595615A patent/NZ595615A/xx unknown
- 2009-03-04 UA UAA201011673A patent/UA101831C2/uk unknown
- 2009-03-04 MX MX2010009794A patent/MX2010009794A/es active IP Right Grant
- 2009-03-09 UA UAA201111603A patent/UA101884C2/uk unknown
- 2009-09-03 CN CN2009800001957A patent/CN101969961B/zh not_active Expired - Fee Related
- 2009-09-03 SG SG10201400171PA patent/SG10201400171PA/en unknown
- 2009-09-03 HR HRP20150418TT patent/HRP20150418T1/hr unknown
- 2009-09-03 US US12/553,355 patent/US8088744B2/en not_active Expired - Fee Related
- 2009-09-03 BR BRPI0924525A patent/BRPI0924525A2/pt not_active IP Right Cessation
2010
- 2010-08-30 IL IL207874A patent/IL207874A/en not_active IP Right Cessation
- 2010-08-31 ZA ZA2010/06228A patent/ZA201006228B/en unknown
- 2010-10-05 CO CO10123058A patent/CO6311080A2/es not_active Application Discontinuation
2011
- 2011-08-25 CO CO11108511A patent/CO6361931A2/es not_active Application Discontinuation
- 2011-09-19 US US13/235,877 patent/US20120009251A1/en not_active Abandoned
- 2011-09-23 US US13/242,184 patent/US20120015025A1/en not_active Abandoned
2012
- 2012-12-05 US US13/705,304 patent/US20130101679A1/en not_active Abandoned
2014
- 2014-02-18 CY CY20141100126T patent/CY1115217T1/el unknown
- 2014-02-28 US US14/193,512 patent/US20140178464A1/en not_active Abandoned
2015
- 2015-09-03 US US14/844,027 patent/US20150374730A1/en not_active Abandoned

Also Published As

Publication number	Publication date
MX2010009794A (es)	2010-12-21
PT2251014E (pt)	2014-02-14
CO6361931A2 (es)	2012-01-20
CY1115217T1 (el)	2017-01-04
HRP20140154T1 (hr)	2014-03-14
BRPI0924525A2 (pt)	2016-03-01
CN101969961B (zh)	2013-01-16
HRP20150418T1 (hr)	2015-05-08
SG10201400171PA (en)	2014-06-27
AU2009220699B2 (en)	2013-06-20
AU2009220699A1 (en)	2009-09-11
JPWO2009110235A1 (ja)	2011-07-14
IL207874A0 (en)	2010-12-30
HK1145455A1 (en)	2011-04-21
US20130101679A1 (en)	2013-04-25
EP2251014A4 (en)	2012-05-23
NZ595615A (en)	2013-06-28
TW200940097A (en)	2009-10-01
ZA201006228B (en)	2011-11-30
ES2437640T3 (es)	2014-01-13
DK2251014T3 (da)	2013-12-02
SG188805A1 (en)	2013-04-30
US20150374730A1 (en)	2015-12-31
AR070857A1 (es)	2010-05-12
IL207874A (en)	2014-05-28
US20120009251A1 (en)	2012-01-12
US8088744B2 (en)	2012-01-03
CO6311080A2 (es)	2011-08-22
UA101831C2 (uk)	2013-05-13
RU2010140611A (ru)	2012-04-10
CN101969961A (zh)	2011-02-09
US20100062053A1 (en)	2010-03-11
EP2251014B8 (en)	2014-01-08
JP5336466B2 (ja)	2013-11-06
US20140178464A1 (en)	2014-06-26
WO2009110235A1 (ja)	2009-09-11
TWI492759B (zh)	2015-07-21
KR20100120674A (ko)	2010-11-16
EP2251014B1 (en)	2013-11-20
SI2251014T1 (sl)	2014-02-28
EP2251014A1 (en)	2010-11-17
CN101678037B (zh)	2012-07-25
CN101678037A (zh)	2010-03-24
CA2717135A1 (en)	2009-09-11
UA101884C2 (uk)	2013-05-13
RU2492865C2 (ru)	2013-09-20
PL2251014T3 (pl)	2014-04-30
AU2009220699C1 (en)	2014-01-16
US20120015025A1 (en)	2012-01-19
NZ587729A (en)	2012-03-30

Legal Events

Date	Code	Title
2017-10-10	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-01-02	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
2018-04-24	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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