BRPI0909055A2 - composto derivado de piridin-2-il, composição farmacêutica que o contém e uso desse composto. - Google Patents

composto derivado de piridin-2-il, composição farmacêutica que o contém e uso desse composto.

Info

Publication number
BRPI0909055A2
BRPI0909055A2 BRPI0909055-0A BRPI0909055A BRPI0909055A2 BR PI0909055 A2 BRPI0909055 A2 BR PI0909055A2 BR PI0909055 A BRPI0909055 A BR PI0909055A BR PI0909055 A2 BRPI0909055 A2 BR PI0909055A2
Authority
BR
Brazil
Prior art keywords
compound
pyridin
pharmaceutical composition
composition containing
derived
Prior art date
Application number
BRPI0909055-0A
Other languages
English (en)
Inventor
Bolli Martin
Lescop Cyrille
Mathys Boris
Mueller Claus
Nayler Oliver
Steiner Beat
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40584746&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0909055(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of BRPI0909055A2 publication Critical patent/BRPI0909055A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

composto derivado de piridin-2-il , composição farmacêutica que o contém e uso desse composto refere-se a presente invenção aos deri vados de p i ridina da fórmula (i) fórmul.a (i) beleci dos na descrição , sua preparação e ao seu uso como compostos farmaceut icamente ativos . os d i tos compostos funcionam parti cul armente como agentes de i munomodulação .
BRPI0909055-0A 2008-03-07 2009-02-25 composto derivado de piridin-2-il, composição farmacêutica que o contém e uso desse composto. BRPI0909055A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IB2008050848 2008-03-07
IBPCT/IB08/050848 2008-03-07
PCT/IB2009/050749 WO2009109872A1 (en) 2008-03-07 2009-02-25 Pyridin-2-yl derivatives as immunomodulating agents

Publications (1)

Publication Number Publication Date
BRPI0909055A2 true BRPI0909055A2 (pt) 2019-02-26

Family

ID=40584746

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0909055-0A BRPI0909055A2 (pt) 2008-03-07 2009-02-25 composto derivado de piridin-2-il, composição farmacêutica que o contém e uso desse composto.

Country Status (26)

Country Link
US (1) US8575200B2 (pt)
EP (1) EP2252609B1 (pt)
JP (1) JP5435745B2 (pt)
KR (1) KR101615779B1 (pt)
CN (1) CN102015695B (pt)
AR (1) AR070858A1 (pt)
AU (1) AU2009220861B2 (pt)
BR (1) BRPI0909055A2 (pt)
CA (1) CA2715437C (pt)
CL (1) CL2009000532A1 (pt)
CY (1) CY1114096T1 (pt)
DK (1) DK2252609T3 (pt)
ES (1) ES2414533T3 (pt)
HR (1) HRP20130641T1 (pt)
IL (1) IL207972A (pt)
MA (1) MA32173B1 (pt)
MX (1) MX2010009644A (pt)
MY (1) MY183039A (pt)
NZ (1) NZ588438A (pt)
PL (1) PL2252609T3 (pt)
PT (1) PT2252609E (pt)
RU (1) RU2494099C2 (pt)
SI (1) SI2252609T1 (pt)
TW (1) TWI444377B (pt)
WO (1) WO2009109872A1 (pt)
ZA (1) ZA201007136B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY149853A (en) * 2006-09-07 2013-10-31 Actelion Pharmaceuticals Ltd Pyridin-4-yl derivatives as immunomodulating agents
EP2069335B1 (en) * 2006-09-08 2012-12-26 Actelion Pharmaceuticals Ltd. Pyridin-3-yl derivatives as immunomodulating agents
EP2069318B1 (en) * 2006-09-21 2012-09-12 Actelion Pharmaceuticals Ltd. Phenyl derivatives and their use as immunomodulators
CN101627034B (zh) * 2007-03-16 2013-05-15 埃科特莱茵药品有限公司 氨基-吡啶衍生物作为s1p1/edg1受体激动剂
US8598208B2 (en) * 2007-08-17 2013-12-03 Actelion Pharmaceuticals Ltd. Pyridine derivatives as S1P1/EDG1 receptor modulators
CA2700917A1 (en) * 2007-11-01 2009-05-07 Actelion Pharmaceuticals Ltd Novel pyrimidine derivatives
MX2012000414A (es) 2009-07-16 2012-02-08 Actelion Pharmaceuticals Ltd Derivados piridin-4-ilo.
BR112012025343A2 (pt) * 2010-04-15 2016-06-28 Merck Patent Gmbh processo para a preparação de hidroquinonas
MY163185A (en) 2011-01-19 2017-08-15 Idorsia Pharmaceuticals Ltd 2-methoxy-pyridin-4-yl derivatives
WO2014141171A1 (en) * 2013-03-15 2014-09-18 Actelion Pharmaceuticals Ltd Pyridin-4-yl derivatives
ES2770348T3 (es) 2015-05-20 2020-07-01 Idorsia Pharmaceuticals Ltd Forma cristalina del compuesto (s)-3-{4-[5-(2-ciclopentil-6-metoxi-piridin-4-il)-[1,2,4]oxadiazol-3-il]-2-etil-6-metil-fenoxi}-propano-1,2-diol

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AU653957B2 (en) 1990-09-20 1994-10-20 Merrell Dow Pharmaceuticals Inc. 1-aryl-3-pyridinyl-2-propene-1-ones
DE4429465A1 (de) * 1994-08-19 1996-02-22 Bayer Ag Verfahren zur Herstellung von 2-Halogenpyridinaldehyden und neue 2-Halogenpyridinaldehyde
JP2003034684A (ja) * 2001-06-29 2003-02-07 Biofor Inc 新規な種類の抗真菌剤
JP2005533058A (ja) * 2002-06-17 2005-11-04 メルク　エンド　カムパニー　インコーポレーテッド Ｅｄｇ受容体アゴニストとしての１−（（５−アリール−１，２，４−オキサジアゾール−３−イル）ベンジル）アゼチジン−３−カルボキシラートおよび１−（（５−アリール−１，２，４−オキサジアゾール−３−イル）ベンジル）ピロリジン−３−カルボキシラート
DE10237883A1 (de) 2002-08-19 2004-03-04 Merckle Gmbh Chem.-Pharm. Fabrik Substituierte Isoxazolderivate und ihre Verwendung in der Pharmazie
WO2004035538A1 (en) * 2002-10-15 2004-04-29 Merck & Co., Inc. Process for making azetidine-3-carboxylic acid
AU2004277947A1 (en) * 2003-10-01 2005-04-14 Merck & Co., Inc. 3,5-aryl, heteroaryl or cycloalkyl substituted-1,2,4-oxadiazoles as S1P receptor agonists
AU2004299456B2 (en) * 2003-12-17 2010-10-07 Merck Sharp & Dohme Corp. (3,4-disubstituted)propanoic carboxylates as S1P (Edg) receptor agonists
WO2006001463A1 (ja) * 2004-06-23 2006-01-05 Ono Pharmaceutical Co., Ltd. Ｓ１ｐ受容体結合能を有する化合物およびその用途
WO2006010379A1 (en) * 2004-07-29 2006-02-02 Actelion Pharmaceuticals Ltd. Novel thiophene derivatives as immunosuppressive agents
ES2519346T3 (es) * 2004-12-13 2014-11-06 Ono Pharmaceutical Co., Ltd. Derivado de ácido azetidinacarboxílico y uso medicinal del mismo
JP5047941B2 (ja) * 2005-03-23 2012-10-10 アクテリオン ファーマシューティカルズ リミテッド 免疫調節物質としての水素付加されたベンゾ（ｃ）チオフェン誘導体
BRPI0609665A2 (pt) * 2005-03-23 2010-04-20 Actelion Pharmaceuticals Ltd composto, composição farmacêutica, e, uso de um composto
RU2404178C2 (ru) * 2005-03-23 2010-11-20 Актелион Фармасьютиклз Лтд Новые производные тиофена в качестве агонистов рецептора сфингозин-1-фосфата-1
MX2007012393A (es) * 2005-04-05 2008-02-22 Pharmacopeia Inc Derivados de purina e imidazopiridina para la inmunosupresion.
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WO2006131336A1 (en) * 2005-06-08 2006-12-14 Novartis Ag POLYCYCLIC OXADIAZOLES OR I SOXAZOLES AND THEIR USE AS SlP RECEPTOR LIGANDS
US20070043104A1 (en) * 2005-06-10 2007-02-22 Luthman Ingrid K UII-modulating compounds and their use
KR20080024533A (ko) * 2005-06-24 2008-03-18 액테리온 파마슈티칼 리미티드 신규한 티오펜 유도체
AR057894A1 (es) * 2005-11-23 2007-12-26 Actelion Pharmaceuticals Ltd Derivados de tiofeno
TWI404706B (zh) * 2006-01-11 2013-08-11 Actelion Pharmaceuticals Ltd 新穎噻吩衍生物
DE602007003074D1 (de) * 2006-01-24 2009-12-17 Actelion Pharmaceuticals Ltd Neue pyrinderivate
UA91129C2 (ru) * 2006-05-09 2010-06-25 Пфайзер Продактс Инк. Производные циклоалкиламинокислот и фармацевтическая композиция, которая их содержит
TWI408139B (zh) * 2006-09-07 2013-09-11 Actelion Pharmaceuticals Ltd 新穎噻吩衍生物
MY149853A (en) * 2006-09-07 2013-10-31 Actelion Pharmaceuticals Ltd Pyridin-4-yl derivatives as immunomodulating agents
EP2069335B1 (en) * 2006-09-08 2012-12-26 Actelion Pharmaceuticals Ltd. Pyridin-3-yl derivatives as immunomodulating agents
EP2069318B1 (en) * 2006-09-21 2012-09-12 Actelion Pharmaceuticals Ltd. Phenyl derivatives and their use as immunomodulators
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EP2109364A4 (en) * 2006-12-15 2010-04-14 Abbott Lab NOVEL OXADIAZONE COMPOUNDS
CN101627034B (zh) * 2007-03-16 2013-05-15 埃科特莱茵药品有限公司 氨基-吡啶衍生物作为s1p1/edg1受体激动剂
US8598208B2 (en) * 2007-08-17 2013-12-03 Actelion Pharmaceuticals Ltd. Pyridine derivatives as S1P1/EDG1 receptor modulators
CA2700917A1 (en) * 2007-11-01 2009-05-07 Actelion Pharmaceuticals Ltd Novel pyrimidine derivatives
CN101896482B (zh) * 2007-12-10 2013-01-09 埃科特莱茵药品有限公司 作为s1p1/edg1激动剂的噻吩衍生物
CA2714614A1 (en) * 2008-03-06 2009-09-11 Actelion Pharmaceuticals Ltd Novel pyrimidine-pyridine derivatives
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WO2009109904A1 (en) * 2008-03-07 2009-09-11 Actelion Pharmaceuticals Ltd Novel aminomethyl benzene derivatives
MX2012000414A (es) * 2009-07-16 2012-02-08 Actelion Pharmaceuticals Ltd Derivados piridin-4-ilo.

Also Published As

Publication number Publication date
ES2414533T3 (es) 2013-07-19
EP2252609B1 (en) 2013-04-17
TWI444377B (zh) 2014-07-11
US8575200B2 (en) 2013-11-05
CN102015695B (zh) 2014-08-27
HRP20130641T1 (en) 2013-08-31
IL207972A (en) 2016-03-31
AR070858A1 (es) 2010-05-12
TW200940532A (en) 2009-10-01
CY1114096T1 (el) 2016-07-27
MA32173B1 (fr) 2011-03-01
ZA201007136B (en) 2014-03-26
RU2010140854A (ru) 2012-04-20
KR101615779B1 (ko) 2016-04-26
JP2011513381A (ja) 2011-04-28
NZ588438A (en) 2012-05-25
US20100331372A1 (en) 2010-12-30
EP2252609A1 (en) 2010-11-24
SI2252609T1 (sl) 2013-07-31
JP5435745B2 (ja) 2014-03-05
CA2715437A1 (en) 2009-09-11
CN102015695A (zh) 2011-04-13
PL2252609T3 (pl) 2013-09-30
AU2009220861B2 (en) 2014-05-29
CA2715437C (en) 2016-05-24
MX2010009644A (es) 2010-09-22
KR20100137493A (ko) 2010-12-30
AU2009220861A1 (en) 2009-09-11
MY183039A (en) 2021-02-08
RU2494099C2 (ru) 2013-09-27
IL207972A0 (en) 2010-12-30
DK2252609T3 (da) 2013-06-24
PT2252609E (pt) 2013-06-24
CL2009000532A1 (es) 2010-04-09
HK1150601A1 (en) 2012-01-06
WO2009109872A1 (en) 2009-09-11

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Legal Events

Date Code Title Description
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: IDORSIA PHARMACEUTICALS LTD (CH)

B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11T Dismissal of application maintained [chapter 11.20 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]