BRPI0912541B8 - composto de benzeno sulfonamida tiazol, sua composição farmacêutica e seu uso - Google Patents

composto de benzeno sulfonamida tiazol, sua composição farmacêutica e seu uso

Info

Publication number
BRPI0912541B8
BRPI0912541B8 BRPI0912541A BRPI0912541A BRPI0912541B8 BR PI0912541 B8 BRPI0912541 B8 BR PI0912541B8 BR PI0912541 A BRPI0912541 A BR PI0912541A BR PI0912541 A BRPI0912541 A BR PI0912541A BR PI0912541 B8 BRPI0912541 B8 BR PI0912541B8
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
compound
thiazole compound
benzene sulphonamide
sulphonamide
Prior art date
Application number
BRPI0912541A
Other languages
English (en)
Inventor
Gregory Waterson Alex
Wilson Brian
Edward Uehling David
Adjabeng George
Schaaf Gregory
M Ralph Jeffrey
Leroy Adams Jerry
Stellwagen John
Hornberger Keith
Kuntz Kevin
Petrov Kimberly
W Johnson Neil
Howard Dickerson Scott
Renae Rheault Tara
Tian Xinrong
Original Assignee
Glaxo Group Ltd
Glaxosmithkline Llc
Novartis Ag
Novartis Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41265326&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0912541(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd, Glaxosmithkline Llc, Novartis Ag, Novartis Pharma Ag filed Critical Glaxo Group Ltd
Publication of BRPI0912541A2 publication Critical patent/BRPI0912541A2/pt
Publication of BRPI0912541B1 publication Critical patent/BRPI0912541B1/pt
Publication of BRPI0912541B8 publication Critical patent/BRPI0912541B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

composto, composição farmacêutica, método para tratar um neoplasma suscetível em um mamífero, processo para preparar um composto, e, uso de um composto a presente invenção proporciona compostos de tiazol sulfonamida e oxazol sulfonamida, composições contendo os mesmos, e também processos para a preparação e métodos para uso dos mesmos como agentes farmacêuticos.
BRPI0912541A 2008-05-06 2009-05-04 composto de benzeno sulfonamida tiazol, sua composição farmacêutica e seu uso BRPI0912541B8 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US5074408P 2008-05-06 2008-05-06
US61/050744 2008-05-06
US61/050,744 2008-05-06
PCT/US2009/042682 WO2009137391A2 (en) 2008-05-06 2009-05-04 Benzene sulfonamide thiazole and oxazole compounds

Publications (3)

Publication Number Publication Date
BRPI0912541A2 BRPI0912541A2 (pt) 2020-08-04
BRPI0912541B1 BRPI0912541B1 (pt) 2021-05-11
BRPI0912541B8 true BRPI0912541B8 (pt) 2021-05-25

Family

ID=41265326

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0912541A BRPI0912541B8 (pt) 2008-05-06 2009-05-04 composto de benzeno sulfonamida tiazol, sua composição farmacêutica e seu uso

Country Status (34)

Country Link
US (6) US7994185B2 (pt)
EP (2) EP2282636B1 (pt)
JP (1) JP5426664B2 (pt)
KR (1) KR101628746B1 (pt)
CN (1) CN102083312B (pt)
AR (1) AR071617A1 (pt)
AU (1) AU2009244491B2 (pt)
BR (1) BRPI0912541B8 (pt)
CA (1) CA2723396C (pt)
CL (1) CL2009001065A1 (pt)
CO (1) CO6321189A2 (pt)
CY (1) CY1117615T1 (pt)
DK (1) DK2282636T3 (pt)
DO (1) DOP2010000326A (pt)
EA (1) EA019349B1 (pt)
ES (1) ES2576684T3 (pt)
HR (1) HRP20160447T1 (pt)
HU (1) HUE028820T2 (pt)
IL (1) IL209018A (pt)
JO (1) JO3408B1 (pt)
MA (1) MA32369B1 (pt)
MX (1) MX2010012074A (pt)
MY (1) MY155317A (pt)
NZ (1) NZ588970A (pt)
PE (1) PE20091952A1 (pt)
PL (1) PL2282636T3 (pt)
RS (1) RS54725B1 (pt)
SG (1) SG190624A1 (pt)
SI (1) SI2282636T1 (pt)
TW (1) TWI432430B (pt)
UA (1) UA103319C2 (pt)
UY (1) UY31806A (pt)
WO (1) WO2009137391A2 (pt)
ZA (1) ZA201007960B (pt)

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