BRPI0913644A2 - processo para a prepração de derivados de pirimidina substituída. - Google Patents

processo para a prepração de derivados de pirimidina substituída.

Info

Publication number: BRPI0913644A2
Authority: BR; Brazil
Prior art keywords: preparation; pyrimidine derivatives; substituted pyrimidine; substituted; derivatives
Prior art date: 2008-06-30

Application number

BRPI0913644A

Other languages

English (en)

Inventor

Christopher M Mapes

Daniel J Pippel

David C Palmer

Hongfeng Chen

Jeffrey S Grimm

Kirk L Sorgi

Neelakandha S Mani

Sergio Cesco-Cancian

Tong Xiao

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-06-30

Filing date

2009-06-29

Publication date

2015-11-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41464882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0913644(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-06-29 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2015-11-24 Publication of BRPI0913644A2 publication Critical patent/BRPI0913644A2/pt

Links

229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
150000003230 pyrimidines Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/20—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
- C07C211/22—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton containing at least two amino groups bound to the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

BRPI0913644A 2008-06-30 2009-06-29 processo para a prepração de derivados de pirimidina substituída. BRPI0913644A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7675208P	2008-06-30	2008-06-30
PCT/US2009/049027 WO2010002774A1 (en)	2008-06-30	2009-06-29	Process for the preparation of substituted pyrimidine derivatives

Publications (1)

Publication Number	Publication Date
BRPI0913644A2 true BRPI0913644A2 (pt)	2015-11-24

Family

ID=41464882

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0913644A BRPI0913644A2 (pt)	2008-06-30	2009-06-29	processo para a prepração de derivados de pirimidina substituída.

Country Status (36)

Country	Link
US (6)	US8309720B2 (pt)
EP (5)	EP2924023A1 (pt)
JP (1)	JP5416768B2 (pt)
KR (1)	KR101675354B1 (pt)
CN (1)	CN102137672B (pt)
AR (1)	AR072396A1 (pt)
AU (1)	AU2009267156B2 (pt)
BR (1)	BRPI0913644A2 (pt)
CA (1)	CA2729733C (pt)
CO (1)	CO6341560A2 (pt)
CY (1)	CY1116134T1 (pt)
DK (1)	DK2310012T3 (pt)
EA (1)	EA019361B1 (pt)
EC (1)	ECSP11010745A (pt)
ES (1)	ES2538135T3 (pt)
HK (3)	HK1201441A1 (pt)
HR (1)	HRP20150576T1 (pt)
HU (1)	HUE024949T2 (pt)
IL (4)	IL210214A (pt)
JO (1)	JO3043B1 (pt)
ME (1)	ME02154B (pt)
MX (1)	MX2011000080A (pt)
MY (1)	MY150601A (pt)
NI (1)	NI201000232A (pt)
NZ (1)	NZ590170A (pt)
PE (1)	PE20110163A1 (pt)
PL (1)	PL2310012T3 (pt)
PT (1)	PT2310012E (pt)
RS (1)	RS53985B1 (pt)
SI (1)	SI2310012T1 (pt)
SV (1)	SV2011003788A (pt)
TW (3)	TW201433568A (pt)
UA (1)	UA106724C2 (pt)
UY (1)	UY31949A (pt)
WO (1)	WO2010002774A1 (pt)
ZA (1)	ZA201100759B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101460483B (zh)	2006-03-31	2013-05-08	詹森药业有限公司	作为组胺h4受体调节剂的苯并咪唑-2-基嘧啶和吡嗪
US9371311B2 (en)	2008-06-30	2016-06-21	Janssen Pharmaceutica Nv	Benzoimidazol-2-yl pyrimidine derivatives
EP2924023A1 (en)	2008-06-30	2015-09-30	Janssen Pharmaceutica NV	piperidine und piperazine derivativs
JP5574294B2 (ja) *	2010-11-04	2014-08-20	独立行政法人科学技術振興機構	光磁気記録媒体及び光磁気記録方法
NZ710640A (en)	2013-03-06	2019-03-29	Janssen Pharmaceutica Nv	Benzoimidazol-2-yl pyrimidine modulators of the histamine h4 receptor
SG11201608114QA (en)	2014-03-28	2016-11-29	Kaneka Corp	Method for producing tri-carbobenzoxy-arginine
MX382290B (es)	2016-11-03	2025-03-13	Bristol Myers Squibb Co	Derivados biciclo hetorocíclicos sustituidos, útiles como inhibidores del canal de potasio medular externo renal (romk).

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RU2276142C2 (ru)	2000-07-21	2006-05-10	Зингента Партисипейшнс Аг	Способ получения 4,6-диметокси-2-метилсульфонилпиримидина (варианты) и применение
PE20020506A1 (es) *	2000-08-22	2002-07-09	Glaxo Group Ltd	Derivados de pirazol fusionados como inhibidores de la proteina cinasa
AU2002258400A1 (en)	2001-02-16	2002-08-28	Tularik Inc.	Methods of using pyrimidine-based antiviral agents
JP2004525150A (ja) *	2001-03-30	2004-08-19	スミスクラインビーチャムコーポレーション	治療用化合物としてのピラゾロピリジン類の使用
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RU2411081C2 (ru) *	2005-07-06	2011-02-10	Джи-И Хелткер Байо-Сайенсиз АБ	Способ изготовления разделяющей матрицы
TW200800201A (en) *	2005-11-18	2008-01-01	Lilly Co Eli	Pyrimidinyl benzothiophene compounds
CN101032483B (zh) *	2006-03-09	2011-05-04	陈德桂	调节雄激素受体活性的乙内酰脲衍生物及其应用
WO2007117400A2 (en) *	2006-03-31	2007-10-18	Janssen Pharmaceutica N.V.	Benzoimidazol-2-yl pyridines as modulators of the histamine h4 receptor
CN101460483B (zh) *	2006-03-31	2013-05-08	詹森药业有限公司	作为组胺h4受体调节剂的苯并咪唑-2-基嘧啶和吡嗪
CN103319459A (zh) *	2008-06-30	2013-09-25	詹森药业有限公司	用于制备苯并咪唑-2-基嘧啶衍生物的方法
EP2924023A1 (en)	2008-06-30	2015-09-30	Janssen Pharmaceutica NV	piperidine und piperazine derivativs

2009
- 2009-06-29 EP EP15157453.0A patent/EP2924023A1/en not_active Withdrawn
- 2009-06-29 EP EP20140161564 patent/EP2769721A3/en not_active Withdrawn
- 2009-06-29 DK DK09774225T patent/DK2310012T3/da active
- 2009-06-29 CN CN200980134933.7A patent/CN102137672B/zh not_active Expired - Fee Related
- 2009-06-29 ES ES09774225.8T patent/ES2538135T3/es active Active
- 2009-06-29 ME MEP-2015-79A patent/ME02154B/me unknown
- 2009-06-29 WO PCT/US2009/049027 patent/WO2010002774A1/en not_active Ceased
- 2009-06-29 UA UAA201100983A patent/UA106724C2/uk unknown
- 2009-06-29 CA CA2729733A patent/CA2729733C/en not_active Expired - Fee Related
- 2009-06-29 HR HRP20150576TT patent/HRP20150576T1/hr unknown
- 2009-06-29 US US12/459,229 patent/US8309720B2/en not_active Expired - Fee Related
- 2009-06-29 PT PT97742258T patent/PT2310012E/pt unknown
- 2009-06-29 AU AU2009267156A patent/AU2009267156B2/en not_active Ceased
- 2009-06-29 MY MYPI2010006258A patent/MY150601A/en unknown
- 2009-06-29 HU HUE09774225A patent/HUE024949T2/en unknown
- 2009-06-29 PL PL09774225T patent/PL2310012T3/pl unknown
- 2009-06-29 NZ NZ590170A patent/NZ590170A/en not_active IP Right Cessation
- 2009-06-29 RS RS20150287A patent/RS53985B1/sr unknown
- 2009-06-29 AR ARP090102405 patent/AR072396A1/es not_active Application Discontinuation
- 2009-06-29 TW TW103118001A patent/TW201433568A/zh unknown
- 2009-06-29 EP EP15157445.6A patent/EP2924035A1/en not_active Withdrawn
- 2009-06-29 MX MX2011000080A patent/MX2011000080A/es active IP Right Grant
- 2009-06-29 EA EA201170113A patent/EA019361B1/ru not_active IP Right Cessation
- 2009-06-29 TW TW103104509A patent/TWI481603B/zh not_active IP Right Cessation
- 2009-06-29 KR KR1020117001991A patent/KR101675354B1/ko not_active Expired - Fee Related
- 2009-06-29 SI SI200931188T patent/SI2310012T1/sl unknown
- 2009-06-29 JO JOP/2009/0240A patent/JO3043B1/ar active
- 2009-06-29 BR BRPI0913644A patent/BRPI0913644A2/pt not_active Application Discontinuation
- 2009-06-29 JP JP2011516757A patent/JP5416768B2/ja not_active Expired - Fee Related
- 2009-06-29 EP EP20090774225 patent/EP2310012B1/en active Active
- 2009-06-29 TW TW098121755A patent/TWI498326B/zh not_active IP Right Cessation
- 2009-06-29 EP EP15157463.9A patent/EP2924025A1/en not_active Withdrawn
- 2009-06-29 PE PE2010001216A patent/PE20110163A1/es not_active Application Discontinuation
- 2009-06-30 UY UY31949A patent/UY31949A/es unknown
2010
- 2010-12-23 NI NI201000232A patent/NI201000232A/es unknown
- 2010-12-23 IL IL210214A patent/IL210214A/en active IP Right Grant
2011
- 2011-01-03 SV SV2011003788A patent/SV2011003788A/es unknown
- 2011-01-04 CO CO11000461A patent/CO6341560A2/es not_active Application Discontinuation
- 2011-01-05 EC ECSP11010745 patent/ECSP11010745A/es unknown
- 2011-01-28 ZA ZA2011/00759A patent/ZA201100759B/en unknown
2012
- 2012-10-29 US US13/663,233 patent/US9079882B2/en not_active Expired - Fee Related
2013
- 2013-03-15 US US13/844,227 patent/US9079883B2/en not_active Expired - Fee Related
- 2013-11-11 US US14/076,955 patent/US9079884B2/en not_active Expired - Fee Related
- 2013-11-12 US US14/078,153 patent/US9006432B2/en not_active Expired - Fee Related
- 2013-11-13 US US14/079,358 patent/US9359327B2/en not_active Expired - Fee Related
2014
- 2014-11-09 IL IL235572A patent/IL235572A/en active IP Right Grant
- 2014-11-09 IL IL235570A patent/IL235570A/en active IP Right Grant
- 2014-11-09 IL IL235571A patent/IL235571A/en active IP Right Grant
2015
- 2015-02-26 HK HK15101911.7A patent/HK1201441A1/en unknown
- 2015-03-23 CY CY20151100293T patent/CY1116134T1/el unknown
2016
- 2016-03-03 HK HK16102449.5A patent/HK1214590A1/en unknown
- 2016-03-23 HK HK16103405.5A patent/HK1215434A1/en unknown

Also Published As

Publication number	Publication date
ECSP11010745A (es)	2011-02-28
ZA201100759B (en)	2012-07-25
EP2924025A1 (en)	2015-09-30
US9079884B2 (en)	2015-07-14
EA201170113A1 (ru)	2011-08-30
IL235572A (en)	2016-09-29
EP2310012A1 (en)	2011-04-20
KR20110023901A (ko)	2011-03-08
US20140073795A1 (en)	2014-03-13
IL210214A0 (en)	2011-03-31
NI201000232A (es)	2011-09-07
DK2310012T3 (da)	2015-03-30
RS53985B1 (sr)	2015-10-30
EP2310012B1 (en)	2015-03-04
UY31949A (es)	2010-01-29
US20140066624A1 (en)	2014-03-06
US20100004450A1 (en)	2010-01-07
US20130225816A1 (en)	2013-08-29
ES2538135T3 (es)	2015-06-17
ME02154B (me)	2015-10-20
AU2009267156A1 (en)	2010-01-07
AR072396A1 (es)	2010-08-25
US8309720B2 (en)	2012-11-13
TW201420583A (zh)	2014-06-01
US9006432B2 (en)	2015-04-14
TW201433568A (zh)	2014-09-01
PL2310012T3 (pl)	2015-08-31
CO6341560A2 (es)	2011-11-21
US20140121374A1 (en)	2014-05-01
JP2011526910A (ja)	2011-10-20
EP2769721A2 (en)	2014-08-27
HK1214590A1 (en)	2016-07-29
HRP20150576T1 (hr)	2015-09-11
US20130053561A1 (en)	2013-02-28
HK1156857A1 (en)	2012-06-22
PE20110163A1 (es)	2011-03-28
HK1215434A1 (en)	2016-08-26
CA2729733C (en)	2016-10-25
MX2011000080A (es)	2011-03-02
US9079883B2 (en)	2015-07-14
TWI498326B (zh)	2015-09-01
SI2310012T1 (sl)	2015-06-30
SV2011003788A (es)	2011-02-08
CY1116134T1 (el)	2017-02-08
CA2729733A1 (en)	2010-01-07
EP2924035A1 (en)	2015-09-30
JP5416768B2 (ja)	2014-02-12
IL235571A (en)	2016-09-29
EP2769721A3 (en)	2015-04-01
KR101675354B1 (ko)	2016-11-11
CN102137672A (zh)	2011-07-27
WO2010002774A1 (en)	2010-01-07
US9079882B2 (en)	2015-07-14
TW201012810A (en)	2010-04-01
EA019361B1 (ru)	2014-03-31
IL210214A (en)	2016-07-31
EP2924023A1 (en)	2015-09-30
HK1201441A1 (en)	2015-09-04
NZ590170A (en)	2012-04-27
IL235570A (en)	2016-08-31
PT2310012E (pt)	2015-04-02
TWI481603B (zh)	2015-04-21
HUE024949T2 (en)	2016-02-29
JO3043B1 (ar)	2016-09-05
CN102137672B (zh)	2014-03-26
EP2310012A4 (en)	2012-06-20
MY150601A (en)	2014-01-30
AU2009267156B2 (en)	2015-05-28
UA106724C2 (uk)	2014-10-10
US9359327B2 (en)	2016-06-07

Legal Events

Date	Code	Title
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2018-11-21	B06T	Formal requirements before examination [chapter 6.20 patent gazette]
2019-04-09	B11E	Dismissal acc. art. 34 of ipl - requirements for examination incomplete
2020-09-24	B11T	Dismissal of application maintained [chapter 11.20 patent gazette]

Publication	Publication Date	Title
BRPI0911254A2 (pt)	2015-10-06	processo para a preparação de um composto
BRPI0916609A2 (pt)	2015-08-04	Processo para a preparação de um macrociclo
BRPI0816258A2 (pt)	2017-05-02	processo para a preparação de compostos úteis como inibidores de sglt
BRPI0910916A2 (pt)	2015-07-28	Processo para a produção de um dianidroaçúcar
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BRPI0817747A2 (pt)	2015-03-31	Processo para a preparação de derivados de ácido 2-di-halogenoacil-3-amino-acrílico
BR112012014490A2 (pt)	2015-09-15	processo para a preparação substituída de 1-o-acil-2-desóxi-2-fluoro-4-tio-beta-d-arabinofuranoses
BRPI0810067A2 (pt)	2014-10-21	Processo para a preparação de capecitabina
BRPI0815784A2 (pt)	2015-02-24	Processo para a preparação de 1,2-propanodiol
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BRPI0911897A2 (pt)	2015-07-28	Processo para a preparação de compostos, e, composto
BRPI1014691A2 (pt)	2015-08-25	Composto, e, processo para a preparação de um composto.
BRPI0813960A2 (pt)	2015-01-06	Processo para produção de biarilas
BRPI0815971A2 (pt)	2015-02-18	Processo para a preparação de 1,2-propanodiol
BRPI0921420A2 (pt)	2016-01-05	processo para preparar compostos
BRPI1013871A2 (pt)	2015-08-25	Processo para a preparação de derivados de ácido propiônico.
BRPI0913644A2 (pt)	2015-11-24	processo para a prepração de derivados de pirimidina substituída.
BRPI0913989A2 (pt)	2015-10-20	processo para preparação de derivados de benzoimidazol-2-il pirirmidina
BRPI0911992A2 (pt)	2015-10-20	processo para preparação de bifenilanilidas substituídas
BRPI0915177A2 (pt)	2016-04-26	processo para fazer 2-amino-tiazolonas substituídas
BRPI0821837A2 (pt)	2015-06-16	Processo para a preparação de 6-substituídas-1-(2h)-isoquinolinonas
BRPI0821471A2 (pt)	2014-12-23	Processo para a preparação de isomalto-oligossacarídeo hidrogenado, e, xarope de isomalto-oligossacarídeo hidrogenado
BR112012002130A2 (pt)	2015-09-15	processo para a preparação de composto,e, composto intermediário
BRPI1010571A2 (pt)	2019-09-24	processo para a preparação de um composto útil como um inibidor de tafla.
BRPI0821752A2 (pt)	2015-06-16	Processo para preparar derivados de ácido 22-fluoracil-3-amino-acrílico