BRPI0914902A2 - composição farmacêutica e método para tratamento de mal de parkinson - Google Patents
composição farmacêutica e método para tratamento de mal de parkinsonInfo
- Publication number
- BRPI0914902A2 BRPI0914902A2 BRPI0914902A BRPI0914902A BRPI0914902A2 BR PI0914902 A2 BRPI0914902 A2 BR PI0914902A2 BR PI0914902 A BRPI0914902 A BR PI0914902A BR PI0914902 A BRPI0914902 A BR PI0914902A BR PI0914902 A2 BRPI0914902 A2 BR PI0914902A2
- Authority
- BR
- Brazil
- Prior art keywords
- disease
- pharmaceutical composition
- treating parkinson
- parkinson
- treating
- Prior art date
Links
- 208000018737 Parkinson disease Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5932608P | 2008-06-06 | 2008-06-06 | |
| US61/059,326 | 2008-06-06 | ||
| PCT/IL2009/000567 WO2009147681A1 (en) | 2008-06-06 | 2009-06-07 | Pharmaceutical compositions for treatment of parkinson's disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0914902A2 true BRPI0914902A2 (pt) | 2017-06-20 |
| BRPI0914902B1 BRPI0914902B1 (pt) | 2022-02-22 |
| BRPI0914902B8 BRPI0914902B8 (pt) | 2022-04-12 |
Family
ID=41051156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0914902A BRPI0914902B8 (pt) | 2008-06-06 | 2009-06-07 | Composição farmacêutica para uso no tratamento de mal de parkinson |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US8969417B2 (pt) |
| EP (1) | EP2303330B2 (pt) |
| JP (1) | JP5648216B2 (pt) |
| KR (1) | KR101613749B1 (pt) |
| CN (1) | CN102105169B (pt) |
| AU (1) | AU2009254730B2 (pt) |
| BR (1) | BRPI0914902B8 (pt) |
| CA (1) | CA2726833C (pt) |
| CL (1) | CL2010001358A1 (pt) |
| CY (1) | CY1119865T1 (pt) |
| DK (1) | DK2303330T4 (pt) |
| ES (1) | ES2659394T5 (pt) |
| HU (1) | HUE037974T2 (pt) |
| LT (1) | LT2303330T (pt) |
| MX (1) | MX2010013393A (pt) |
| NO (1) | NO2303330T3 (pt) |
| NZ (1) | NZ590291A (pt) |
| PL (1) | PL2303330T5 (pt) |
| PT (1) | PT2303330T (pt) |
| RU (1) | RU2540470C9 (pt) |
| WO (1) | WO2009147681A1 (pt) |
| ZA (1) | ZA201100034B (pt) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102791258B (zh) | 2010-02-03 | 2018-05-08 | 图必制药公司 | 雷沙吉兰的延长释放制剂及其用途 |
| TW201304822A (zh) * | 2010-11-15 | 2013-02-01 | Vectura Ltd | 組成物及用途 |
| US20150079187A1 (en) * | 2012-01-12 | 2015-03-19 | Pharma Two B Ltd. | Fixed dose combination therapy of parkinson's disease |
| US9504657B2 (en) * | 2012-01-12 | 2016-11-29 | Pharmatwob Ltd. | Fixed dose combination therapy of Parkinson's disease |
| WO2013168032A1 (en) * | 2012-05-07 | 2013-11-14 | Micro Labs Limited | Pharmaceutical compositions comprising rasagiline |
| KR101320945B1 (ko) * | 2012-07-03 | 2013-10-23 | 주식회사파마킹 | 에스-알릴-엘-시스테인을 유효성분으로 포함하는 대장염 예방 또는 치료용 조성물 및 이를 포함하는 의약제제 |
| US20140088145A1 (en) * | 2012-09-27 | 2014-03-27 | Teva Pharmaceutical Industries, Ltd. | Combination of rasagiline and pridopidine for treating neurodegenerative disorders, in particular huntington's disease |
| BR112015022896B1 (pt) | 2013-03-15 | 2022-08-23 | Chongxi Yu | Composto de fármacos de alta penetração, composição farmacêutica e seus usos para o tratamento de doenças de parkinson |
| EP2808023A1 (en) * | 2013-05-30 | 2014-12-03 | Université Pierre et Marie Curie (Paris 6) | New drug for the treatment and/or prevention of depressive disorders |
| CN104473942A (zh) * | 2014-12-12 | 2015-04-01 | 青岛大学 | 一种抗帕金森氏病的药物组合物 |
| CN107660147B (zh) | 2015-05-26 | 2021-04-30 | 抗菌技术生物技术研究与发展股份有限公司 | 用于治疗帕金森病和相关障碍的组合物 |
| WO2017070293A1 (en) * | 2015-10-20 | 2017-04-27 | Ironwood Pharmaceuticals, Inc. | Phosphodiesterase 9 inhibitor and levodopa therapy |
| US20170143681A1 (en) * | 2015-11-02 | 2017-05-25 | Apkarian Technologies Llc | Methods and compositions for treating pain |
| EP3558378A4 (en) * | 2016-12-22 | 2020-09-16 | Synnerva Ltd. | LOW DOSE COMBINATION OF MEDICINAL PRODUCTS FOR THE PREVENTION AND TREATMENT OF NEURAL DAMAGE |
| WO2019010491A1 (en) * | 2017-07-07 | 2019-01-10 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | COMBINATIONS OF MEDICINES FOR THE PROTECTION AGAINST THE DEATH OF NEURONAL CELLS |
| US20190153102A1 (en) | 2017-09-28 | 2019-05-23 | Prothena Biosciences Limited | Dosing regimes for treatment of synucleinopathies |
| JP6596483B2 (ja) * | 2017-12-28 | 2019-10-23 | テックフィールズ ファーマ カンパニー リミテッド | パ−キンソン病治療用の新規高透過薬物及びその組成物 |
| WO2020084168A1 (en) * | 2018-10-26 | 2020-04-30 | Icm (Institut Du Cerveau Et De La Moelle Épinière) | Tetracycline compound for treating drug-induced dyskinesia |
| CN113924086A (zh) * | 2019-04-17 | 2022-01-11 | 维奇健康科学有限责任公司 | 液体药物组合物 |
| CA3139559A1 (en) * | 2019-05-09 | 2020-11-12 | Apkarian Technologies Llc | Methods and compositions for treating pain |
| JP2023504876A (ja) * | 2019-12-06 | 2023-02-07 | シャンハイ ファーマシューティカルズ ホールディング カンパニー,リミティド | 薬物組成物、キット及びその応用 |
| EP4167971A1 (en) | 2020-06-18 | 2023-04-26 | XWPharma Ltd. | Controlled release granulations of water-soluble active pharmaceutical ingredients |
| WO2022020621A1 (en) | 2020-07-24 | 2022-01-27 | XWPharma Ltd. | Pharmaceutical compositions and pharmacokinetics of a gamma-hydroxybutyric acid derivative |
| KR20230086674A (ko) * | 2020-09-10 | 2023-06-15 | 프로테나 바이오사이언시즈 리미티드 | 파킨슨 질환의 치료 |
| CN119970650A (zh) | 2020-10-05 | 2025-05-13 | 凯瑞康宁生物工程有限公司 | γ-羟基丁酸衍生物的修饰释放组合物 |
| CN114762684B (zh) * | 2021-01-14 | 2023-11-21 | 华益泰康药业股份有限公司 | 一种治疗帕金森的缓释胶囊及其制备方法 |
| EP4308086B1 (en) | 2021-03-19 | 2025-10-15 | XWPharma Ltd. | Pharmacokinetics of combined release formulations of a gamma-hydroxybutyric acid derivative |
| KR102903389B1 (ko) * | 2022-11-30 | 2025-12-23 | 주식회사한국파마 | 신경퇴행성 질환 예방 또는 치료용 필름코팅정제 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE55245T1 (de) * | 1986-04-16 | 1990-08-15 | Asta Pharma Ag | Synergistische kombination von amantadin und selegilin. |
| US5190763A (en) | 1990-05-07 | 1993-03-02 | Alza Corporation | Dosage form indicated for the management of abnormal posture, tremor and involuntary movement |
| US5221536A (en) | 1990-05-07 | 1993-06-22 | Alza Corporation | Dosage form indicated for the management of abnormal posture, tremor and involuntary movement |
| ES2211904T3 (es) * | 1995-05-26 | 2004-07-16 | Pfizer Inc. | Combinaciones para el tratamiento del parkinsonismo que contienen antagonistas selectivos de nmda. |
| CA2407031A1 (en) | 2000-04-19 | 2001-10-25 | Lilly Icos Llc | Use of cyclic gmp-specific phosphodiesterase inhibitors for treatment of parkinson's disease |
| US20070225379A1 (en) * | 2001-08-03 | 2007-09-27 | Carrara Dario Norberto R | Transdermal delivery of systemically active central nervous system drugs |
| AR044007A1 (es) * | 2003-04-11 | 2005-08-24 | Newron Pharmaceuticals Inc | Metodos para el tratamiento de la enfermedad de parkinson |
| FR2857594B1 (fr) * | 2003-07-17 | 2005-09-16 | Servier Lab | Composition pharmaceutique pour l'administration par voie nasale de piribedil |
| JP2007523122A (ja) | 2004-02-20 | 2007-08-16 | ノバルティス アクチエンゲゼルシャフト | 神経変性障害および認知障害の処置のためのdpp−iv阻害剤 |
| WO2007002518A1 (en) | 2005-06-23 | 2007-01-04 | Spherics, Inc. | Delayed release or extended-delayed release dosage forms of pramipexole |
| WO2007048034A2 (en) | 2005-10-21 | 2007-04-26 | Caritas St. Elizabeth Medical Center Of Boston, Inc. | Use of androgens for the treatment of parkinson' s disease |
| EP1970055B1 (en) | 2005-12-29 | 2010-11-24 | Osmotica Kereskedelmi És Szolgáltató Kft | Multi-layered tablet with triple release combination |
| BRPI0708071A8 (pt) | 2006-02-17 | 2017-12-26 | Birds Pharma Gmbh Berolina Innovative Res & Development Services | Derivados de catecolamina deuterada e medicamentos compreendendo os ditos compostos |
| EP2007369A4 (en) | 2006-04-03 | 2009-07-01 | Teva Pharma | USE OF RASAGILINE FOR THE TREATMENT OF LEG SYNDROME WITHOUT REST |
| KR20090021169A (ko) | 2006-05-16 | 2009-02-27 | 크놉 뉴로사이언시스 인코포레이티드 | R(+) 및 s(-) 프라미펙솔을 포함하는 조성물 및 이의 사용 방법 |
| WO2008008398A2 (en) | 2006-07-14 | 2008-01-17 | Shionogi & Co., Ltd. | Oxime compounds and the use thereof |
| US7531572B2 (en) | 2006-07-28 | 2009-05-12 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs of α-amino acids, methods of synthesis and use |
| EP2056818B1 (en) | 2006-08-11 | 2011-05-25 | The Johns Hopkins University | Compositions and methods for neuroprotection |
| US20100093706A1 (en) | 2006-08-21 | 2010-04-15 | Prexa Pharmaceuticals, Inc. | Multimediator transporter inhibitors for use in treatment of central nervous system disorders |
| US7622495B2 (en) | 2006-10-03 | 2009-11-24 | Neurim Pharmaceuticals (1991) Ltd. | Substituted aryl-indole compounds and their kynurenine/kynuramine-like metabolites as therapeutic agents |
| PT2079485E (pt) | 2006-11-01 | 2012-08-13 | Purdue Pharma Lp | Compostos fenilpropionamida e a sua utilização |
| WO2008129043A1 (en) * | 2007-04-24 | 2008-10-30 | Boehringer Ingelheim International Gmbh | Combination with an extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof |
-
2009
- 2009-06-07 MX MX2010013393A patent/MX2010013393A/es active IP Right Grant
- 2009-06-07 HU HUE09758025A patent/HUE037974T2/hu unknown
- 2009-06-07 NO NO09758025A patent/NO2303330T3/no unknown
- 2009-06-07 CA CA2726833A patent/CA2726833C/en active Active
- 2009-06-07 CN CN200980129250.2A patent/CN102105169B/zh active Active
- 2009-06-07 RU RU2010154716/15A patent/RU2540470C9/ru active
- 2009-06-07 KR KR1020117000189A patent/KR101613749B1/ko active Active
- 2009-06-07 WO PCT/IL2009/000567 patent/WO2009147681A1/en not_active Ceased
- 2009-06-07 US US12/996,455 patent/US8969417B2/en active Active
- 2009-06-07 AU AU2009254730A patent/AU2009254730B2/en active Active
- 2009-06-07 LT LTEP09758025.2T patent/LT2303330T/lt unknown
- 2009-06-07 DK DK09758025.2T patent/DK2303330T4/da active
- 2009-06-07 ES ES09758025T patent/ES2659394T5/es active Active
- 2009-06-07 PT PT97580252T patent/PT2303330T/pt unknown
- 2009-06-07 NZ NZ590291A patent/NZ590291A/xx not_active IP Right Cessation
- 2009-06-07 EP EP09758025.2A patent/EP2303330B2/en active Active
- 2009-06-07 PL PL09758025T patent/PL2303330T5/pl unknown
- 2009-06-07 BR BRPI0914902A patent/BRPI0914902B8/pt active IP Right Grant
- 2009-06-07 JP JP2011512269A patent/JP5648216B2/ja active Active
-
2010
- 2010-12-06 CL CL2010001358A patent/CL2010001358A1/es unknown
-
2011
- 2011-01-03 ZA ZA2011/00034A patent/ZA201100034B/en unknown
-
2015
- 2015-01-22 US US14/602,518 patent/US9259418B2/en active Active - Reinstated
-
2018
- 2018-01-31 CY CY20181100112T patent/CY1119865T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO EM FUNCAO DA REVOGACAO DO ART. 229-C DA LEI NO 9.279, DE 1996, POR FORCA DA LEI NO 14.195, DE 2021 |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 07/06/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: REF. RPI 2668 DE 22/02/2022 QUANTO AO ENDERECO. |