BRPI0915073A2 - composições e métodos compreendendo proteases microbianas variantes - Google Patents

composições e métodos compreendendo proteases microbianas variantes

Info

Publication number
BRPI0915073A2
BRPI0915073A2 BRPI0915073A BRPI0915073A BRPI0915073A2 BR PI0915073 A2 BRPI0915073 A2 BR PI0915073A2 BR PI0915073 A BRPI0915073 A BR PI0915073A BR PI0915073 A BRPI0915073 A BR PI0915073A BR PI0915073 A2 BRPI0915073 A2 BR PI0915073A2
Authority
BR
Brazil
Prior art keywords
compositions
methods
microbial proteases
variant microbial
variant
Prior art date
Application number
BRPI0915073A
Other languages
English (en)
Inventor
A Estell David
Goedegebuur Frits
T Kellis James Jr
G Cascao-Pereira Luis
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of BRPI0915073A2 publication Critical patent/BRPI0915073A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/189Enzymes
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38681Chemically modified or immobilised enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D2111/00Cleaning compositions characterised by the objects to be cleaned; Cleaning compositions characterised by non-standard cleaning or washing processes
    • C11D2111/10Objects to be cleaned
    • C11D2111/12Soft surfaces, e.g. textile
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21062Subtilisin (3.4.21.62)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fodder In General (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
BRPI0915073A 2008-06-06 2009-06-03 composições e métodos compreendendo proteases microbianas variantes BRPI0915073A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5969508P 2008-06-06 2008-06-06
PCT/US2009/046156 WO2009149200A2 (en) 2008-06-06 2009-06-03 Compositions and methods comprising variant microbial proteases

Publications (1)

Publication Number Publication Date
BRPI0915073A2 true BRPI0915073A2 (pt) 2019-09-24

Family

ID=41009802

Family Applications (3)

Application Number Title Priority Date Filing Date
BRPI0913623A BRPI0913623A8 (pt) 2008-06-06 2009-06-03 Composições e métodos compreendendo variantes de proteases microbianas
BRPI0915681-0A BRPI0915681A2 (pt) 2008-06-06 2009-06-03 Composições e métodos compreendendo proteases microbianas variantes
BRPI0915073A BRPI0915073A2 (pt) 2008-06-06 2009-06-03 composições e métodos compreendendo proteases microbianas variantes

Family Applications Before (2)

Application Number Title Priority Date Filing Date
BRPI0913623A BRPI0913623A8 (pt) 2008-06-06 2009-06-03 Composições e métodos compreendendo variantes de proteases microbianas
BRPI0915681-0A BRPI0915681A2 (pt) 2008-06-06 2009-06-03 Composições e métodos compreendendo proteases microbianas variantes

Country Status (13)

Country Link
US (12) US20110256610A1 (pt)
EP (10) EP2947147A3 (pt)
JP (8) JP6067221B2 (pt)
KR (3) KR20110015006A (pt)
CN (7) CN104694519B (pt)
AU (3) AU2009256169A1 (pt)
BR (3) BRPI0913623A8 (pt)
CA (3) CA2726370A1 (pt)
DK (2) DK2297314T3 (pt)
MX (6) MX360255B (pt)
RU (2) RU2541786C2 (pt)
WO (3) WO2009149145A2 (pt)
ZA (1) ZA201008169B (pt)

Families Citing this family (134)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2472725C (en) * 2002-01-16 2015-08-11 Genencor International, Inc. Multiply-substituted protease variants
US20090060933A1 (en) * 2004-06-14 2009-03-05 Estell David A Proteases producing an altered immunogenic response and methods of making and using the same
CN104694519B (zh) * 2008-06-06 2023-10-27 丹尼斯科美国公司 包含微生物蛋白酶变体的组合物和方法
MX339402B (es) 2008-11-11 2016-05-25 Danisco Us Inc Composiciones y metodos que comprenden variantes de serina proteasa.
EP2362896A2 (en) 2008-11-11 2011-09-07 Danisco US Inc. Bacillus subtilisin comprising one or more combinable mutations
CN102574914A (zh) * 2009-07-16 2012-07-11 葛兰素集团有限公司 改进的抗血清清蛋白结合性单可变区
RU2639534C2 (ru) * 2009-09-25 2017-12-21 Новозимс А/С Применение вариантов протеазы
BR112012014082B1 (pt) * 2009-12-09 2020-12-15 Danisco Us Inc variante de protease isolada e seu método de produção, ácido nucleico isolado, vetor de expressão, célula hospedeira recombinante, composição e método para limpeza de um item ou de uma superfície em necessidade de limpeza
EP4159833A3 (en) 2009-12-09 2023-07-26 The Procter & Gamble Company Fabric and home care products
US20120067373A1 (en) * 2010-04-15 2012-03-22 Philip Frank Souter Automatic Dishwashing Detergent Composition
CN108410585A (zh) * 2010-05-06 2018-08-17 宝洁公司 具有蛋白酶变体的消费品
CN103764823B (zh) * 2011-05-05 2018-05-11 丹尼斯科美国公司 包含丝氨酸蛋白酶变体的组合物和方法
JP5933688B2 (ja) * 2011-05-05 2016-06-15 ザ プロクター アンド ギャンブル カンパニー セリンプロテアーゼ変異体を含む組成物及び方法
JP2015500006A (ja) * 2011-11-25 2015-01-05 ノボザイムス アクティーゼルスカブ サブチラーゼ変異体およびこれをコードするポリヌクレオチド
JP2015504660A (ja) * 2011-12-20 2015-02-16 ノボザイムス アクティーゼルスカブ サブチラーゼ変異体およびそれをコードするポリヌクレオチド
EP2607468A1 (en) * 2011-12-20 2013-06-26 Henkel AG & Co. KGaA Detergent compositions comprising subtilase variants
US10093911B2 (en) * 2012-02-17 2018-10-09 Novozymes A/S Subtilisin variants and polynucleotides encoding same
EP2628785B1 (en) * 2012-02-17 2016-05-18 Henkel AG & Co. KGaA Detergent compositions comprising subtilase variants
EP3354728B1 (en) 2012-12-21 2020-04-22 Danisco US Inc. Alpha-amylase variants
WO2014099525A1 (en) 2012-12-21 2014-06-26 Danisco Us Inc. Paenibacillus curdlanolyticus amylase, and methods of use, thereof
CN110777132B (zh) 2013-03-11 2024-03-22 丹尼斯科美国公司 α-淀粉酶组合变体
WO2014194054A1 (en) 2013-05-29 2014-12-04 Danisco Us Inc. Novel metalloproteases
WO2014194117A2 (en) 2013-05-29 2014-12-04 Danisco Us Inc. Novel metalloproteases
US20160160202A1 (en) 2013-05-29 2016-06-09 Danisco Us Inc. Novel metalloproteases
EP4159854A1 (en) 2013-05-29 2023-04-05 Danisco US Inc Novel metalloproteases
US20160145596A1 (en) 2013-06-27 2016-05-26 Novozymes A/S Subtilase Variants and Polynucleotides Encoding Same
US10647974B2 (en) 2013-06-27 2020-05-12 Novozymes A/S Subtilase variants and polynucleotides encoding same
JP6678108B2 (ja) * 2013-09-12 2020-04-08 ダニスコ・ユーエス・インク Lg12−系統群プロテアーゼ変異体を含む組成物及び方法
WO2015057619A1 (en) 2013-10-15 2015-04-23 Danisco Us Inc. Clay granule
EP3068879B1 (en) 2013-11-14 2019-12-25 Danisco US Inc. Stable enzymes by glycation reduction
EP3514230B1 (en) 2013-12-13 2021-09-22 Danisco US Inc. Serine proteases of bacillus species
WO2015089447A1 (en) 2013-12-13 2015-06-18 Danisco Us Inc. Serine proteases of the bacillus gibsonii-clade
AU2014366222B2 (en) 2013-12-16 2018-07-19 Nutrition & Biosciences USA 4, Inc. Use of poly alpha-1,3-glucan ethers as viscosity modifiers
JP6559139B2 (ja) 2013-12-18 2019-08-14 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーE.I.Du Pont De Nemours And Company カチオン性ポリα−1,3−グルカンエーテル
WO2015112339A1 (en) 2014-01-22 2015-07-30 The Procter & Gamble Company Fabric treatment composition
WO2015112340A1 (en) 2014-01-22 2015-07-30 The Procter & Gamble Company Method of treating textile fabrics
EP3097172A1 (en) 2014-01-22 2016-11-30 The Procter & Gamble Company Method of treating textile fabrics
EP3097175B1 (en) 2014-01-22 2018-10-17 The Procter and Gamble Company Fabric treatment composition
US20150232785A1 (en) 2014-02-14 2015-08-20 E I Du Pont De Nemours And Company Polysaccharides for viscosity modification
ES2734726T3 (es) 2014-03-11 2019-12-11 Du Pont Poli alfa-1,2-glucano oxidado como reforzante de detergente
JP6585698B2 (ja) 2014-03-21 2019-10-02 ダニスコ・ユーエス・インク バチルス(Bacillus)種のセリンプロテアーゼ
US9714403B2 (en) 2014-06-19 2017-07-25 E I Du Pont De Nemours And Company Compositions containing one or more poly alpha-1,3-glucan ether compounds
EP3158043B1 (en) 2014-06-19 2021-03-10 Nutrition & Biosciences USA 4, Inc. Compositions containing one or more poly alpha-1,3-glucan ether compounds
US10626388B2 (en) 2014-07-04 2020-04-21 Novozymes A/S Subtilase variants and polynucleotides encoding same
EP3207129B1 (en) 2014-10-17 2019-11-20 Danisco US Inc. Serine proteases of bacillus species
BR112017007949A2 (pt) 2014-10-24 2018-01-23 Danisco Us Inc método para produção de álcool pelo uso de uma tripeptidil-peptidase
US20180010074A1 (en) 2014-10-27 2018-01-11 Danisco Us Inc. Serine proteases of bacillus species
EP3212781B1 (en) 2014-10-27 2019-09-18 Danisco US Inc. Serine proteases
WO2016069544A1 (en) 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases
WO2016069552A1 (en) 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases
EP3957729A1 (en) 2014-10-27 2022-02-23 Danisco US Inc. Serine proteases
MX2017006377A (es) 2014-11-17 2017-08-21 Procter & Gamble Composiciones de suministro de agentes beneficos.
EP3690037A1 (en) * 2014-12-04 2020-08-05 Novozymes A/S Subtilase variants and polynucleotides encoding same
CN116286218A (zh) * 2014-12-04 2023-06-23 诺维信公司 包括蛋白酶变体的液体清洁组合物
WO2016096711A2 (en) 2014-12-15 2016-06-23 Novozymes A/S Subtilase variants
DK3234093T3 (da) * 2014-12-19 2020-08-17 Novozymes As Proteasevarianter og polynukleotider, som koder for dem
JP2018512109A (ja) 2014-12-23 2018-05-17 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーE.I.Du Pont De Nemours And Company 酵素により製造されるセルロース
US20180216090A1 (en) * 2015-03-12 2018-08-02 Danisco Us Inc. Compositions and methods comprising lg12-clade protease variants
CN107532116B (zh) 2015-04-29 2021-05-07 宝洁公司 处理织物的方法
US20160319227A1 (en) 2015-04-29 2016-11-03 The Procter & Gamble Company Method of treating a fabric
DK3088505T3 (da) 2015-04-29 2020-08-03 Procter & Gamble Fremgangsmåde til behandling af et tekstilstof
JP2018521149A (ja) 2015-04-29 2018-08-02 ザ プロクター アンド ギャンブル カンパニー 洗剤組成物
WO2016176280A1 (en) 2015-04-29 2016-11-03 The Procter & Gamble Company Method of treating a fabric
EP3294884B1 (en) 2015-05-13 2021-01-27 Danisco US Inc. Aprl-clade protease variants and uses thereof
FI3307427T3 (fi) 2015-06-09 2023-11-09 Danisco Us Inc Osmoottiset puhkeavat kapselit
WO2016201040A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc. Water-triggered enzyme suspension
WO2016201069A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc Low-density enzyme-containing particles
EP4234693A3 (en) 2015-06-17 2023-11-01 Danisco US Inc Bacillus gibsonii-clade serine proteases
WO2017079756A1 (en) 2015-11-05 2017-05-11 Danisco Us Inc Paenibacillus and bacillus spp. mannanases
WO2017079751A1 (en) 2015-11-05 2017-05-11 Danisco Us Inc Paenibacillus sp. mannanases
WO2017083229A1 (en) 2015-11-13 2017-05-18 E. I. Du Pont De Nemours And Company Glucan fiber compositions for use in laundry care and fabric care
JP6997706B2 (ja) 2015-11-13 2022-01-18 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー,インコーポレイテッド 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物
JP7045313B2 (ja) 2015-11-13 2022-03-31 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー,インコーポレイテッド 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物
WO2017089093A1 (en) 2015-11-25 2017-06-01 Unilever N.V. A liquid detergent composition
EP3387124B1 (en) 2015-12-09 2021-05-19 Danisco US Inc. Alpha-amylase combinatorial variants
US20180362946A1 (en) 2015-12-18 2018-12-20 Danisco Us Inc. Polypeptides with endoglucanase activity and uses thereof
DE102016205670A1 (de) * 2016-04-06 2017-10-12 Henkel Ag & Co. Kgaa Neue Protease mit verbesserter Waschleistung
CA3022875A1 (en) * 2016-05-03 2017-11-09 Danisco Us Inc Protease variants and uses thereof
US11661567B2 (en) 2016-05-31 2023-05-30 Danisco Us Inc. Protease variants and uses thereof
MX2018015559A (es) 2016-06-17 2019-06-06 Danisco Us Inc Variantes de proteasa y sus usos.
EP3535365A2 (en) 2016-11-07 2019-09-11 Danisco US Inc. Laundry detergent composition
US10550443B2 (en) 2016-12-02 2020-02-04 The Procter & Gamble Company Cleaning compositions including enzymes
MX2019006422A (es) 2016-12-02 2019-08-01 Procter & Gamble Composiciones de limpieza que incluyen enzimas.
WO2018102478A1 (en) 2016-12-02 2018-06-07 The Procter & Gamble Company Cleaning compositions including enzymes
EP4424805A3 (en) 2016-12-21 2024-11-20 Danisco Us Inc Bacillus gibsonii-clade serine proteases
US20200392477A1 (en) 2016-12-21 2020-12-17 Danisco Us Inc. Protease variants and uses thereof
WO2018169750A1 (en) 2017-03-15 2018-09-20 Danisco Us Inc Trypsin-like serine proteases and uses thereof
US20200040283A1 (en) 2017-03-31 2020-02-06 Danisco Us Inc Delayed release enzyme formulations for bleach-containing detergents
JP7680825B2 (ja) 2017-06-30 2025-05-21 ダニスコ・ユーエス・インク 低凝集の酵素含有粒子
CN109819650A (zh) * 2017-09-25 2019-05-28 春布里泽·格奥尔基·格奥尔基耶维奇 具有抗病毒和抗细菌活性的热稳定组合物及其用途
WO2019108599A1 (en) 2017-11-29 2019-06-06 Danisco Us Inc Subtilisin variants having improved stability
CN111742041B (zh) 2017-12-21 2023-06-06 丹尼斯科美国公司 包含耐热干燥剂的含酶的热熔细粒
MX2020008302A (es) 2018-02-08 2020-10-14 Danisco Us Inc Partículas de matriz de cera térmicamente resistentes para encapsulación de enzimas.
EP3799601A1 (en) 2018-06-19 2021-04-07 Danisco US Inc. Subtilisin variants
WO2019245704A1 (en) 2018-06-19 2019-12-26 Danisco Us Inc Subtilisin variants
US20210189295A1 (en) 2018-08-30 2021-06-24 Danisco Us Inc Enzyme-containing granules
WO2020068486A1 (en) 2018-09-27 2020-04-02 Danisco Us Inc Compositions for medical instrument cleaning
CN111019925B (zh) * 2018-10-10 2022-08-23 上饶市康可得生物科技有限公司 筛选蛋白酶变体的方法以及获得的蛋白酶变体
WO2020073553A1 (zh) * 2018-10-10 2020-04-16 上饶市康可得生物科技有限公司 筛选蛋白酶变体的方法以及获得的蛋白酶变体
US12509672B2 (en) * 2018-11-28 2025-12-30 Danisco Us Inc. Subtilisin variants having improved stability
CN109481336B (zh) * 2018-12-19 2021-10-26 广州立白企业集团有限公司 口腔护理组合物及其应用
CN114174504A (zh) 2019-05-24 2022-03-11 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
CN114174486A (zh) 2019-06-06 2022-03-11 丹尼斯科美国公司 用于清洁的方法和组合物
IT201900023433A1 (it) 2019-12-10 2021-06-10 Lonati Spa Dispositivo prelevatore per operare il prelievo di un manufatto tubolare a maglia da una macchina circolare per maglieria, calzetteria o simile
US20240034960A1 (en) 2020-08-27 2024-02-01 Danisco Us Inc Enzymes and enzyme compositions for cleaning
EP4284906A1 (en) 2021-01-29 2023-12-06 Danisco US Inc. Compositions for cleaning and methods related thereto
WO2022171667A1 (en) * 2021-02-12 2022-08-18 Fresenius Kabi Ipsum S.R.L. Subtilisin variants and their use
CN112877304B (zh) * 2021-03-15 2022-07-26 合肥师范学院 一种细菌漆酶突变体LacAt及其表达菌株的构建和应用
US20240294888A1 (en) 2021-06-30 2024-09-05 Danisco Us Inc. Variant enzymes and uses thereof
EP4396320A2 (en) 2021-09-03 2024-07-10 Danisco US Inc. Laundry compositions for cleaning
CN117957318A (zh) 2021-09-13 2024-04-30 丹尼斯科美国公司 含有生物活性物质的颗粒
EP4448750A2 (en) 2021-12-16 2024-10-23 Danisco US Inc. Subtilisin variants and uses thereof
US20250051748A1 (en) 2021-12-16 2025-02-13 Danisco Us Inc. Subtilisin variants and methods of use
CN118679252A (zh) 2021-12-16 2024-09-20 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
CN118974227A (zh) 2022-03-01 2024-11-15 丹尼斯科美国公司 用于清洁的酶和酶组合物
CN114733656B (zh) * 2022-04-25 2024-01-23 江苏泓润生物质能科技有限公司 一种用于预处理后的餐厨垃圾同步分相除渣及除杂系统
CA3257053A1 (en) 2022-05-14 2023-11-23 Novozymes A/S COMPOSITIONS AND METHODS FOR THE PREVENTION, TREATMENT, SUPPRESSION AND/OR ELIMINATION OF PHYTOPATHOGENIC INFESTATIONS AND INFECTIONS
CN119487167A (zh) 2022-06-21 2025-02-18 丹尼斯科美国公司 用于清洁的包含具有嗜热菌蛋白酶活性的多肽的组合物和方法
EP4581138A1 (en) 2022-09-02 2025-07-09 Danisco US Inc. Subtilisin variants and methods related thereto
CA3265943A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. DETERGENT COMPOSITIONS AND ASSOCIATED PROCESSES
WO2024050339A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Mannanase variants and methods of use
EP4615968A1 (en) 2022-11-09 2025-09-17 Danisco US Inc. Subtilisin variants and methods of use
WO2024163600A1 (en) * 2023-02-01 2024-08-08 Danisco Us Inc. Subtilisin variants and methods of use
EP4658776A1 (en) 2023-02-01 2025-12-10 Danisco US Inc. Subtilisin variants and methods of use
US20240263162A1 (en) * 2023-02-01 2024-08-08 The Procter & Gamble Company Detergent compositions containing enzymes
CN120712348A (zh) 2023-03-06 2025-09-26 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
EP4680013A1 (en) 2023-03-16 2026-01-21 Nutrition & Biosciences USA 4, Inc. Brevibacillus fermentate extracts for cleaning and malodor control and use thereof
WO2025072144A1 (en) * 2023-09-27 2025-04-03 Osprey Biopharmaceuticals, Inc. Polypeptides having human igg cleavage activity
WO2025071996A1 (en) 2023-09-28 2025-04-03 Danisco Us Inc. Variant cutinase enzymes with improved solubility and uses thereof
WO2025085351A1 (en) 2023-10-20 2025-04-24 Danisco Us Inc. Subtilisin variants and methods of use
CN117417922B (zh) * 2023-12-13 2024-03-15 北京科为博生物科技有限公司 一种耐高温碱性蛋白酶及其基因和应用
WO2026024921A1 (en) 2024-07-25 2026-01-29 The Procter & Gamble Company Detergent composition comprising a subtilisin variant and methods of use
WO2026050315A1 (en) 2024-08-29 2026-03-05 Danisco Us Inc. Subtilisin variants and methods of use
CN120197407B (zh) * 2025-05-27 2025-08-12 南京华洲药业有限公司 一种除草剂悬浮剂分散稳定性预估优化方法及系统

Family Cites Families (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1296839A (pt) 1969-05-29 1972-11-22
GB1372034A (en) 1970-12-31 1974-10-30 Unilever Ltd Detergent compositions
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
GR76237B (pt) 1981-08-08 1984-08-04 Procter & Gamble
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
US5411873A (en) * 1984-05-29 1995-05-02 Genencor, Inc. Process for producing heterologous polypeptides
US5801038A (en) * 1984-05-29 1998-09-01 Genencor International Inc. Modified subtilisins having amino acid alterations
US5972682A (en) 1984-05-29 1999-10-26 Genencor International, Inc. Enzymatically active modified subtilisins
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
DK154572C (da) 1985-08-07 1989-04-24 Novo Industri As Enzymatisk detergentadditiv, detergent og fremgangsmaade til vask af tekstiler
JPH0697997B2 (ja) 1985-08-09 1994-12-07 ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ 新規の酵素的洗浄剤添加物
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
IE65767B1 (en) * 1986-04-30 1995-11-15 Genencor Int Non-human carbonyl hydrolase mutants DNA sequences and vectors encoding same and hosts transformed with said vectors
US5322770A (en) 1989-12-22 1994-06-21 Hoffman-Laroche Inc. Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription
US4810414A (en) 1986-08-29 1989-03-07 Novo Industri A/S Enzymatic detergent additive
US4914031A (en) * 1987-04-10 1990-04-03 Amgen, Inc. Subtilisin analogs
EP0322429B1 (en) 1987-05-29 1994-10-19 Genencor International, Inc. Cutinase cleaning composition
EP0305216B1 (en) 1987-08-28 1995-08-02 Novo Nordisk A/S Recombinant Humicola lipase and process for the production of recombinant humicola lipases
JPS6474992A (en) 1987-09-16 1989-03-20 Fuji Oil Co Ltd Dna sequence, plasmid and production of lipase
DE68924654T2 (de) 1988-01-07 1996-04-04 Novonordisk As Spezifische Protease.
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体dna、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
US4977252A (en) 1988-03-11 1990-12-11 National Starch And Chemical Investment Holding Corporation Modified starch emulsifier characterized by shelf stability
WO1990009446A1 (en) 1989-02-17 1990-08-23 Plant Genetic Systems N.V. Cutinase
CA2034486A1 (en) 1989-06-26 1990-12-27 Eric Casteleijn Enzymatic detergent compositions
DK316989D0 (da) * 1989-06-26 1989-06-26 Novo Nordisk As Enzymer
US5665587A (en) * 1989-06-26 1997-09-09 Novo Nordisk A/S Modified subtilisins and detergent compositions containing same
DE59101948D1 (de) 1990-04-14 1994-07-21 Kali Chemie Ag Alkalische bacillus-lipasen, hierfür codierende dna-sequenzen sowie bacilli, die diese lipasen produzieren.
US5354559A (en) 1990-05-29 1994-10-11 Grain Processing Corporation Encapsulation with starch hydrolyzate acid esters
US5766898A (en) * 1990-12-05 1998-06-16 Novo Nordisk A/S Proteins with changed epitopes and methods for the production thereof
ES2174820T3 (es) 1991-01-16 2002-11-16 Procter & Gamble Composiciones detergentes compactas con celulasa de alta actividad.
US5340735A (en) 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
JP4028592B2 (ja) * 1992-07-17 2007-12-26 ジェネンコー インターナショナル インコーポレイテッド 高アルカリ性セリンプロテアーゼ
DE4231726A1 (de) * 1992-09-23 1994-03-24 Cognis Bio Umwelt Mutierte subtilisinartige Serinproteasen
CA2145420C (en) * 1992-09-24 2005-01-04 Stanley E. Mainzer Cleaning compositions containing novel alkaline proteases
BR9307576A (pt) 1992-12-01 1999-06-15 Novo Nordisk As Processo para oxidar um substrato com uma enzima peroxidase ou um composto atuando como peroxidase na presença de uma fonte de peróxido de hidrogênio aditivo detergente e composição detergente
CA2154157C (en) 1993-01-18 1999-08-03 Fiona Susan Macbeath Machine dishwashing detergent compositions
DK77393D0 (da) 1993-06-29 1993-06-29 Novo Nordisk As Aktivering af enzymer
US5698504A (en) 1993-07-01 1997-12-16 The Procter & Gamble Company Machine dishwashing composition containing oxygen bleach and paraffin oil and benzotriazole compound silver tarnishing inhibitors
US5486303A (en) 1993-08-27 1996-01-23 The Procter & Gamble Company Process for making high density detergent agglomerates using an anhydrous powder additive
BR9407502A (pt) * 1993-09-15 1997-01-07 Procter & Gamble Variantes subtilisina bpn com adsorção diminuída e hidrólise aumentada
US6436690B1 (en) * 1993-09-15 2002-08-20 The Procter & Gamble Company BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
ATE245185T1 (de) * 1993-10-14 2003-08-15 Procter & Gamble Proteasen enthaltende bleichmittelzusammensetzungen
MA23346A1 (fr) * 1993-10-14 1995-04-01 Genencor Int Variantes de la subtilisine
ES2287931T3 (es) * 1993-10-14 2007-12-16 THE PROCTER & GAMBLE COMPANY Composiciones limpiadoras que contienen proteasa.
DE4342680A1 (de) 1993-12-15 1995-06-22 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
US5861271A (en) 1993-12-17 1999-01-19 Fowler; Timothy Cellulase enzymes and systems for their expressions
ES2364774T3 (es) 1994-02-24 2011-09-14 HENKEL AG & CO. KGAA Enzimas mejoradas y detergentes que las contienen.
EP1921147B1 (en) 1994-02-24 2011-06-08 Henkel AG & Co. KGaA Improved enzymes and detergents containing them
US5691295A (en) 1995-01-17 1997-11-25 Cognis Gesellschaft Fuer Biotechnologie Mbh Detergent compositions
US5686014A (en) 1994-04-07 1997-11-11 The Procter & Gamble Company Bleach compositions comprising manganese-containing bleach catalysts
WO1995035362A1 (en) 1994-06-17 1995-12-28 Genencor International Inc. Cleaning compositions containing plant cell wall degrading enzymes and their use in cleaning methods
GB2294268A (en) 1994-07-07 1996-04-24 Procter & Gamble Bleaching composition for dishwasher use
GB9416841D0 (en) * 1994-08-19 1994-10-12 Finnfeeds Int Ltd An enzyme feed additive and animal feed including it
US5879584A (en) 1994-09-10 1999-03-09 The Procter & Gamble Company Process for manufacturing aqueous compositions comprising peracids
US5691297A (en) 1994-09-20 1997-11-25 The Procter & Gamble Company Process for making a high density detergent composition by controlling agglomeration within a dispersion index
US5516448A (en) 1994-09-20 1996-05-14 The Procter & Gamble Company Process for making a high density detergent composition which includes selected recycle streams for improved agglomerate
US5489392A (en) 1994-09-20 1996-02-06 The Procter & Gamble Company Process for making a high density detergent composition in a single mixer/densifier with selected recycle streams for improved agglomerate properties
DK0796317T3 (da) 1994-12-09 2000-06-05 Procter & Gamble Diacylperoxidpartikelholdig sammensætning til automatisk opvask
US5534179A (en) 1995-02-03 1996-07-09 Procter & Gamble Detergent compositions comprising multiperacid-forming bleach activators
US5574005A (en) 1995-03-07 1996-11-12 The Procter & Gamble Company Process for producing detergent agglomerates from high active surfactant pastes having non-linear viscoelastic properties
US5569645A (en) 1995-04-24 1996-10-29 The Procter & Gamble Company Low dosage detergent composition containing optimum proportions of agglomerates and spray dried granules for improved flow properties
CN1192774A (zh) 1995-06-16 1998-09-09 普罗格特-甘布尔公司 包含钴催化剂的自动洗餐具用组合物
US5597936A (en) 1995-06-16 1997-01-28 The Procter & Gamble Company Method for manufacturing cobalt catalysts
US5565422A (en) 1995-06-23 1996-10-15 The Procter & Gamble Company Process for preparing a free-flowing particulate detergent composition having improved solubility
DE19530816A1 (de) 1995-08-23 1997-02-27 Cognis Bio Umwelt Verwendung von mutierter Subtilisin-Protease in kosmetischen Produkten
US5576282A (en) 1995-09-11 1996-11-19 The Procter & Gamble Company Color-safe bleach boosters, compositions and laundry methods employing same
DE69635936T2 (de) 1995-09-18 2006-12-28 The Procter & Gamble Company, Cincinnati Riechstofffreisetzungssystem
US5879564A (en) 1995-11-14 1999-03-09 Cytec Technology Corp. High performance polymer flocculating agents
MA24137A1 (fr) 1996-04-16 1997-12-31 Procter & Gamble Fabrication d'agents de surface ramifies .
ATE409743T1 (de) * 1996-11-04 2008-10-15 Novozymes As Subtilase varianten und verbindungen
WO1998020115A1 (en) * 1996-11-04 1998-05-14 Novo Nordisk A/S Subtilase variants and compositions
AU6226198A (en) 1997-03-07 1998-09-22 Procter & Gamble Company, The Improved methods of making cross-bridged macropolycycles
CN1262632C (zh) 1997-03-07 2006-07-05 普罗格特-甘布尔公司 含有金属漂白催化剂和漂白活化剂和/或有机过羧酸的漂白组合物
CN1272881A (zh) * 1997-08-29 2000-11-08 诺沃挪第克公司 蛋白酶变体及组合物
RU2252958C2 (ru) * 1997-10-23 2005-05-27 Джененкор Интернэшнл, Инк. Вариант субтилизина (варианты), кодирующая его днк, экспрессирующий вектор, очищающая композиция, корм для животных, композиция для обработки ткани
MA24811A1 (fr) * 1997-10-23 1999-12-31 Procter & Gamble Compositions de lavage contenant des variantes de proteases multisubstituees
US5935826A (en) 1997-10-31 1999-08-10 National Starch And Chemical Investment Holding Corporation Glucoamylase converted starch derivatives and their use as emulsifying and encapsulating agents
DE69830743T2 (de) 1997-11-21 2006-04-27 Novozymes A/S Protease-varianten und zusammensetzungen
US6773907B2 (en) * 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
CA2313950A1 (en) 1997-12-24 1999-07-08 James T. Kellis, Jr. An improved method of assaying for a preferred enzyme and /or preferred detergent composition
US6936249B1 (en) * 1998-04-15 2005-08-30 Genencor International, Inc. Proteins producing an altered immunogenic response and methods of making and using the same
MXPA00012241A (es) 1998-06-10 2002-06-04 Novozymes As Mananasas novedosas.
US6461849B1 (en) * 1998-10-13 2002-10-08 Novozymes, A/S Modified polypeptide
US6376450B1 (en) 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
EP1135392A2 (en) 1998-11-30 2001-09-26 The Procter & Gamble Company Process for preparing cross-bridged tetraaza macrocycles
DK1141205T3 (da) * 1998-12-18 2007-06-18 Novozymes As Subtilase-enzymer fra I-S1 og I-S2 sub-grupperne, som har en yderligere aminosyrerest i en aktiv site loop region
AU773063B2 (en) * 1998-12-18 2004-05-13 Novozymes A/S Subtilase enzymes of the I-S1 and I-S2 sub-groups having an additional amino acid residue in an active site loop region
JP4768128B2 (ja) * 1998-12-18 2011-09-07 ノボザイムス アクティーゼルスカブ 活性部位ループ領域中に追加のアミノ酸残基を有するサブチラーゼ酵素サブグループi−s1及びi−s2
CN100415880C (zh) * 1999-05-20 2008-09-03 诺沃奇梅兹有限公司 在97与98位之间具有至少一个额外氨基酸残基的i-s1和i-s2亚组枯草杆菌酶
AU6085800A (en) * 1999-07-22 2001-02-13 Procter & Gamble Company, The Subtilisin protease variants having amino acid substitutions in defined epitope regions
CA2396974C (en) * 2000-02-23 2006-06-27 The Procter & Gamble Company Liquid laundry detergent compositions having enhanced clay removal benefits
DE60144145D1 (de) * 2000-04-03 2011-04-14 Maxygen Inc Subtilisin-variante
WO2001083559A2 (en) * 2000-04-28 2001-11-08 Novozymes A/S Production and use of protein variants having modified immunogenecity
ATE400648T1 (de) 2000-08-11 2008-07-15 Genencor Int Transformation von bacillus, transformanten und mutanten-bibliotheken
US6541235B1 (en) * 2000-09-29 2003-04-01 University Of Maryland Biotechnology Institute Calcium free subtilisin mutants
US6440991B1 (en) 2000-10-02 2002-08-27 Wyeth Ethers of 7-desmethlrapamycin
US6582914B1 (en) 2000-10-26 2003-06-24 Genencor International, Inc. Method for generating a library of oligonucleotides comprising a controlled distribution of mutations
DK1373296T3 (da) * 2001-03-23 2012-01-09 Procter & Gamble Proteiner, der frembringer et ændret immunogent respons, og fremgangsmåder til fremstilling og anvendelse deraf
JP2005515180A (ja) * 2001-11-13 2005-05-26 ザ プロクター アンド ギャンブル カンパニー 阻害物質で安定化させた酵素を含有する局所適用組成物
CA2795814A1 (en) * 2001-12-31 2003-07-17 Genencor International, Inc. Proteases producing an altered immunogenic response and methods of making and using the same
WO2003057246A1 (en) * 2001-12-31 2003-07-17 Genencor International, Inc. Proteases producing an altered immunological response and methods of making and using the same
CA2472725C (en) * 2002-01-16 2015-08-11 Genencor International, Inc. Multiply-substituted protease variants
JP4597528B2 (ja) * 2002-02-26 2010-12-15 ジェネンコー・インターナショナル・インク 免疫原性が減少したズブチリシン・カールスバーグタンパク質
TWI319007B (en) * 2002-11-06 2010-01-01 Novozymes As Subtilase variants
US7888093B2 (en) * 2002-11-06 2011-02-15 Novozymes A/S Subtilase variants
US20040214737A1 (en) * 2003-04-25 2004-10-28 John Billman Foamy composition for pretreatment of stains on fabrics
EP1627885B8 (en) * 2003-04-30 2015-02-18 Innovative Medicine and Any Peptide Pharmaceuticals Corp Polypeptide capable of assisting digestive organ absorption
JP5244317B2 (ja) 2003-11-19 2013-07-24 ジェネンコー・インターナショナル・インク セリンプロテアーゼ、セリン酵素をコードする核酸、およびこれらを取り込んだベクターおよび宿主細胞
ES2361838T3 (es) 2003-12-03 2011-06-22 Danisco Us Inc. Perhidrolasa.
CN1938422A (zh) 2004-04-08 2007-03-28 金克克国际有限公司 突变体α-淀粉酶
DE102004027091A1 (de) * 2004-06-02 2005-12-29 Henkel Kgaa Leistungsverbesserte Alkalische Protease-Varianten und Wasch- und Reinigungsmittel, enthaltend diese leistungsverbesserten Alkalische Protease-Varianten
EP2385112B1 (en) * 2005-07-08 2016-11-30 Novozymes A/S Subtilase variants
AR055444A1 (es) 2005-10-12 2007-08-22 Procter & Gamble Uso y produccion de metalopretasa neutra estable al almacenamiento
JP2009534022A (ja) * 2006-04-20 2009-09-24 ノボザイムス アクティーゼルスカブ 卵のシミに対する洗浄能力が向上したサビナーゼ変異体
WO2007145963A2 (en) * 2006-06-05 2007-12-21 The Procter & Gamble Company Enzyme stabilization
KR20150115023A (ko) * 2006-07-18 2015-10-13 다니스코 유에스 인크. 광범위한 온도에 걸쳐 활성인 프로테아제 변이형
CN104694519B (zh) * 2008-06-06 2023-10-27 丹尼斯科美国公司 包含微生物蛋白酶变体的组合物和方法
MX339402B (es) * 2008-11-11 2016-05-25 Danisco Us Inc Composiciones y metodos que comprenden variantes de serina proteasa.
BR112012014082B1 (pt) * 2009-12-09 2020-12-15 Danisco Us Inc variante de protease isolada e seu método de produção, ácido nucleico isolado, vetor de expressão, célula hospedeira recombinante, composição e método para limpeza de um item ou de uma superfície em necessidade de limpeza
EP4159833A3 (en) * 2009-12-09 2023-07-26 The Procter & Gamble Company Fabric and home care products
EP2551335A1 (en) * 2011-07-25 2013-01-30 The Procter & Gamble Company Enzyme stabilized liquid detergent composition
US20130123162A1 (en) * 2011-11-10 2013-05-16 The Procter & Gamble Company Consumer products

Also Published As

Publication number Publication date
CN102112607B (zh) 2014-08-20
CN102057043A (zh) 2011-05-11
EP2297314A2 (en) 2011-03-23
US20220025350A1 (en) 2022-01-27
ZA201008169B (en) 2012-02-29
EP2947147A2 (en) 2015-11-25
DK2297314T3 (en) 2015-07-13
JP2013240327A (ja) 2013-12-05
US20240309352A1 (en) 2024-09-19
US20180051269A1 (en) 2018-02-22
CN104694519B (zh) 2023-10-27
AU2009256169A1 (en) 2009-12-10
BRPI0913623A8 (pt) 2017-10-03
MX360255B (es) 2018-10-26
EP2647701A2 (en) 2013-10-09
CN103382421B (zh) 2016-01-20
US20150064767A1 (en) 2015-03-05
US12448616B2 (en) 2025-10-21
WO2009149200A3 (en) 2010-07-29
EP2947147A3 (en) 2015-12-23
EP2297316A2 (en) 2011-03-23
CN104694519A (zh) 2015-06-10
CN103382420A (zh) 2013-11-06
US20110256610A1 (en) 2011-10-20
MX383345B (es) 2025-03-13
WO2009149144A2 (en) 2009-12-10
CN102057043B (zh) 2015-03-04
JP2018050618A (ja) 2018-04-05
AU2009256294A1 (en) 2009-12-10
EP2297315A2 (en) 2011-03-23
EP2578680B1 (en) 2016-04-27
US10563189B2 (en) 2020-02-18
US20150247140A1 (en) 2015-09-03
CN103382420B (zh) 2015-10-28
EP2647702A2 (en) 2013-10-09
BRPI0915681A2 (pt) 2015-08-04
RU2010153866A (ru) 2012-07-20
CN102046783A (zh) 2011-05-04
US20150159147A1 (en) 2015-06-11
KR20110015006A (ko) 2011-02-14
JP2015211671A (ja) 2015-11-26
CA2726451A1 (en) 2009-12-10
KR20110020245A (ko) 2011-03-02
US20180223269A1 (en) 2018-08-09
EP3095859A1 (en) 2016-11-23
KR20110015004A (ko) 2011-02-14
US20110251073A1 (en) 2011-10-13
EP2647702A3 (en) 2013-12-25
MX2010013100A (es) 2010-12-21
CN104130993B (zh) 2018-10-23
JP2011522537A (ja) 2011-08-04
EP2647701A3 (en) 2013-12-25
CN103382421A (zh) 2013-11-06
JP2011522539A (ja) 2011-08-04
BRPI0913623A2 (pt) 2015-08-04
CA2726450A1 (en) 2009-12-10
US20110256609A1 (en) 2011-10-20
EP3173479A1 (en) 2017-05-31
RU2010153864A (ru) 2012-07-20
CN104130993A (zh) 2014-11-05
CA2726370A1 (en) 2009-12-10
JP5647976B2 (ja) 2015-01-07
MX350188B (es) 2017-08-30
RU2541786C2 (ru) 2015-02-20
JP2011524166A (ja) 2011-09-01
AU2009256295A1 (en) 2009-12-10
WO2009149145A2 (en) 2009-12-10
JP6067221B2 (ja) 2017-01-25
DK2578680T3 (en) 2016-08-15
EP2297314B1 (en) 2015-04-15
JP2015012864A (ja) 2015-01-22
JP6426391B2 (ja) 2018-11-21
JP2013223499A (ja) 2013-10-31
WO2009149144A3 (en) 2010-04-15
MX2010013121A (es) 2011-01-21
WO2009149145A3 (en) 2010-01-28
RU2010154103A (ru) 2012-07-20
US20150056682A1 (en) 2015-02-26
CN102112607A (zh) 2011-06-29
MX2010013101A (es) 2010-12-21
EP2578679A1 (en) 2013-04-10
WO2009149200A2 (en) 2009-12-10
US20200190497A1 (en) 2020-06-18
EP2578680A1 (en) 2013-04-10
US12410420B2 (en) 2025-09-09

Similar Documents

Publication Publication Date Title
BRPI0915681A2 (pt) Composições e métodos compreendendo proteases microbianas variantes
BRPI0922084A2 (pt) Composições e métodos compreendendo variantes de serina protease
PT2356462T (pt) Composições e métodos anti-cxcr1
BRPI0920284A2 (pt) composição e método
BRPI0921822A2 (pt) composição compreendendo polímero e enzima
BRPI0907231A2 (pt) pirrolpirimidinas e pirrolpiridinas
BRPI0912046A2 (pt) composições de hibridização e métodos
BRPI0716325A2 (pt) Composição antimicrobianas
EP2510094A4 (en) COMPOSITIONS AND METHODS WITH PROTEASE VARIANTS
BRPI0906749A2 (pt) Composição
BRPI0913808A2 (pt) composição
IT1392101B1 (it) Composizione comprendente isoflavoni
BRPI0905715A2 (pt) Composição farmacêutica e kit de componentes
BRPI0917231A2 (pt) composição
EP2374452A4 (en) NUTRIENT COMPOSITION
BRPI0918328B8 (pt) composição e artigo
EP2043136A4 (en) FILMING COMPOSITION
BRPI0917172A2 (pt) Composição bacteriana
FR2899479B1 (fr) Composition cicatrisante
BRPI0913807A2 (pt) composição e artigo
PL2240018T3 (pl) Kompozycja zawierająca środek przeciwbólowy i przeciwhistaminowy
BRPI0717073A2 (pt) Composição detergente e método
BRPI0909218A2 (pt) composição tensoativas
DK2334596T3 (da) Ferriphosphatbaseret sammensætning og anvendelse heraf
BRPI0918579A2 (pt) composição de gel tensoativa

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.