BRPI1008949A8 - Cetoenóis haloalquilmetilenóxi-fenil-substituídos e seu uso, composição, seu uso e seu método de produção, métodos para combate de pestes animais e/ou crescimento de plantas indesejadas - Google Patents
Cetoenóis haloalquilmetilenóxi-fenil-substituídos e seu uso, composição, seu uso e seu método de produção, métodos para combate de pestes animais e/ou crescimento de plantas indesejadasInfo
- Publication number
- BRPI1008949A8 BRPI1008949A8 BRPI1008949A BRPI1008949A BRPI1008949A8 BR PI1008949 A8 BRPI1008949 A8 BR PI1008949A8 BR PI1008949 A BRPI1008949 A BR PI1008949A BR PI1008949 A BRPI1008949 A BR PI1008949A BR PI1008949 A8 BRPI1008949 A8 BR PI1008949A8
- Authority
- BR
- Brazil
- Prior art keywords
- haloalkylmethyleneoxy
- phenyl
- methods
- growth
- unwanted plants
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 230000012010 growth Effects 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 241001465754 Metazoa Species 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 230000000895 acaricidal effect Effects 0.000 abstract 1
- 239000000642 acaricide Substances 0.000 abstract 1
- 244000038559 crop plants Species 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000002363 herbicidal effect Effects 0.000 abstract 1
- 239000004009 herbicide Substances 0.000 abstract 1
- 239000002917 insecticide Substances 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 239000000575 pesticide Substances 0.000 abstract 1
- 150000004714 phosphonium salts Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/76—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C235/78—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
- A01N43/38—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
- A01N47/06—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing —O—CO—O— groups; Thio analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/54—Spiro-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrane Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
CETOENÓIS HALOALQUILMETILENÓXI-FENIL-SUBSTITUÍDOS E SEU USO, COMPOSIÇÃO, SEU USO E SEU MÉTODO DE PRODUÇÃO, MÉTODOS PARA COMBATE DE PESTES ANIMAIS E/OU CRESCIMENTO DE PLANTAS INDESEJADAS. A presente invenção refere-se a compostos novos da fórmula(l), onde W, X, Y, Z e CKE apresentam respectivamente o significado acima citado, a diversos métodos e produtos intermediários para fabricação destes e ao uso destes como pesticidas e/ou herbicidas. A invenção também refere-se a composições herbicidas seletivas que compreendem primeiramente cetoenóis haloalquilmetilenóxi-fenil-substituídos e em segundo lugar um composto que melhora a compatibilidade de planta de cultura. A presente invençao além disso refere-se ao aumento da ação de composições de proteção de culturas compreendendo especialmente cetoenóis haloalquilmetilenóxi-fenil-substituídos mediante adição de sais de amônio ou de fosfônio e opcionalmente melhoradores de penetração, às composições correspondentes, a métodos para a produção destas e ao uso destas na proteção de cultura como inseticidas e/ou acaricidas e/ou para impedir o crescimento de plantas indesejadas.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09154888 | 2009-03-11 | ||
| EP09154888.3 | 2009-03-11 | ||
| PCT/EP2010/001392 WO2010102758A2 (de) | 2009-03-11 | 2010-03-05 | Halogenalkylmethylenoxy-phenyl-substituierte ketoenole |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI1008949A2 BRPI1008949A2 (pt) | 2015-09-01 |
| BRPI1008949A8 true BRPI1008949A8 (pt) | 2016-05-03 |
| BRPI1008949B1 BRPI1008949B1 (pt) | 2018-07-10 |
Family
ID=41228842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1008949-7A BRPI1008949B1 (pt) | 2009-03-11 | 2010-03-05 | Cetoenóis haloalquilmetilenóxi-fenil-substituídos e seu uso, composição, seu uso e seu método de produção, métodos para combate de pestes animais e/ou crescimento de plantas indesejadas |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8518985B2 (pt) |
| EP (2) | EP3153503A1 (pt) |
| JP (1) | JP5840955B2 (pt) |
| KR (1) | KR101703633B1 (pt) |
| CN (2) | CN102348684B (pt) |
| AR (1) | AR075848A1 (pt) |
| AU (1) | AU2010223535B2 (pt) |
| BR (1) | BRPI1008949B1 (pt) |
| CA (1) | CA2754847C (pt) |
| EA (1) | EA024266B1 (pt) |
| ES (1) | ES2632567T3 (pt) |
| HU (1) | HUE035166T2 (pt) |
| MX (2) | MX338802B (pt) |
| PL (1) | PL2406216T3 (pt) |
| WO (1) | WO2010102758A2 (pt) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI1008949B1 (pt) | 2009-03-11 | 2018-07-10 | Bayer Intellectual Property Gmbh | Cetoenóis haloalquilmetilenóxi-fenil-substituídos e seu uso, composição, seu uso e seu método de produção, métodos para combate de pestes animais e/ou crescimento de plantas indesejadas |
| KR20120099396A (ko) * | 2009-09-09 | 2012-09-10 | 바이엘 크롭사이언스 아게 | 식물병원성 박테리아를 구제하기 위한 사이클릭 케토에놀의 용도 |
| JP5892949B2 (ja) | 2010-02-10 | 2016-03-23 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH | ビフェニル置換環状ケトエノール類 |
| ES2545113T3 (es) | 2010-02-10 | 2015-09-08 | Bayer Intellectual Property Gmbh | Derivados de ácido tetrámico sustituidos de manera espiroheterocíclica |
| DE102010008644A1 (de) | 2010-02-15 | 2011-08-18 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Zyklische Ketoenole zur Therapie |
| WO2011131623A1 (de) | 2010-04-20 | 2011-10-27 | Bayer Cropscience Ag | Insektizide und/oder herbizide zusammensetzung mit verbesserter wirkung auf basis von spiroheterocyclisch-substituierten tetramsäure-derivaten |
| EP2719680A1 (de) * | 2010-11-02 | 2014-04-16 | Bayer Intellectual Property GmbH | Phenylsubstituierte Bicyclooktan-1,3-dion-Derivate |
| JP5951642B2 (ja) | 2011-01-25 | 2016-07-13 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH | 1−h−ピロリジン−2,4−ジオン誘導体を製造する方法 |
| DE102011011040A1 (de) | 2011-02-08 | 2012-08-09 | Bayer Pharma Aktiengesellschaft | (5s,8s)-3-(4'-Chlor-3'-fluor-4-methylbiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-on (Verbindung A) zur Therapie |
| EP2675788A1 (de) | 2011-02-17 | 2013-12-25 | Bayer Intellectual Property GmbH | Substituierte 3-(biphenyl-3-yl)-8,8-difluor-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-one zur therapie |
| DE102011080405A1 (de) | 2011-08-04 | 2013-02-07 | Bayer Pharma AG | Substituierte 3-(Biphenyl-3-yl)-8,8-difluor-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-one zur Therapie |
| US9204640B2 (en) | 2011-03-01 | 2015-12-08 | Bayer Intellectual Property Gmbh | 2-acyloxy-pyrrolin-4-ones |
| EP2683695B1 (de) | 2011-03-11 | 2015-08-05 | Bayer Intellectual Property GmbH | Cis-alkoxysubstituierte spirocyclische 1-h-pyrrolidin-2,4-dion-derivate |
| JP5878816B2 (ja) * | 2011-05-12 | 2016-03-08 | 住友化学株式会社 | 粒子の製造方法 |
| DE102011080406A1 (de) | 2011-08-04 | 2013-02-07 | Bayer Pharma AG | Substituierte 3-(Biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro8[4.5]dec-3-en-2-one |
| UA116804C2 (uk) | 2013-04-19 | 2018-05-10 | Сінгента Лімітед | Гербіцидно активні сполуки 2-(заміщений феніл)-циклопентан-1,3-діону та їх похідні |
| GB201310047D0 (en) | 2013-06-05 | 2013-07-17 | Syngenta Ltd | Compounds |
| RU2608369C2 (ru) * | 2014-03-31 | 2017-01-18 | Кей Эм Ю Ко., Лтд. | Стыковочная конструкция внешних стеновых материалов |
| TWI735416B (zh) | 2014-10-06 | 2021-08-11 | 美商維泰克斯製藥公司 | 囊腫纖維化症跨膜傳導調節蛋白之調節劑 |
| PL3310759T3 (pl) * | 2015-06-22 | 2019-09-30 | Bayer Cropscience Aktiengesellschaft | Nowe podstawione alkinylowo 3-fenylopirrolidyno-2,4-diony i ich zastosowanie jako herbicydy |
| ES2886953T3 (es) | 2016-01-15 | 2021-12-21 | Bayer Cropscience Ag | Procedimiento para la preparación de 2-(4-cloro-2,6-dimetilfenil)etanol |
| ES2946970T3 (es) | 2016-03-31 | 2023-07-28 | Vertex Pharma | Regulador de conductancia transmembrana de moduladores de fibrosis quística |
| WO2017178314A1 (de) * | 2016-04-14 | 2017-10-19 | Bayer Cropscience Aktiengesellschaft | Anellierte 3-phenyltetramsäure-derivate mit herbizider wirkung |
| SI3519401T1 (sl) | 2016-09-30 | 2022-01-31 | Vertex Pharmaceuticals Incorporated | Modulator regulatorja transmembranske prevodnosti pri cistični fibrozi, farmacevtski sestavki, postopki zdravljenja in proces za izdelavo modulatorja |
| CN110267948B (zh) | 2016-12-09 | 2023-12-08 | 弗特克斯药品有限公司 | 囊性纤维化跨膜传导调控剂的调节剂、药物组合物、治疗方法和制备所述调节剂的方法 |
| AU2018279646B2 (en) | 2017-06-08 | 2023-04-06 | Vertex Pharmaceuticals Incorporated | Methods of treatment for cystic fibrosis |
| MA49631A (fr) | 2017-07-17 | 2020-05-27 | Vertex Pharma | Méthodes de traitement de la fibrose kystique |
| TWI799435B (zh) | 2017-08-02 | 2023-04-21 | 美商維泰克斯製藥公司 | 製備化合物之製程 |
| US10654829B2 (en) | 2017-10-19 | 2020-05-19 | Vertex Pharmaceuticals Incorporated | Crystalline forms and compositions of CFTR modulators |
| KR102716244B1 (ko) | 2017-12-08 | 2024-10-14 | 버텍스 파마슈티칼스 인코포레이티드 | 낭포성 섬유증 막횡단 전도 조절자의 조정제의 제조 방법 |
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-
2010
- 2010-03-05 BR BRPI1008949-7A patent/BRPI1008949B1/pt not_active IP Right Cessation
- 2010-03-05 WO PCT/EP2010/001392 patent/WO2010102758A2/de not_active Ceased
- 2010-03-05 MX MX2013011965A patent/MX338802B/es unknown
- 2010-03-05 CA CA2754847A patent/CA2754847C/en not_active Expired - Fee Related
- 2010-03-05 KR KR1020117023789A patent/KR101703633B1/ko not_active Expired - Fee Related
- 2010-03-05 PL PL10708924T patent/PL2406216T3/pl unknown
- 2010-03-05 CN CN201080011864.3A patent/CN102348684B/zh not_active Expired - Fee Related
- 2010-03-05 EP EP16193742.0A patent/EP3153503A1/de not_active Withdrawn
- 2010-03-05 AU AU2010223535A patent/AU2010223535B2/en not_active Ceased
- 2010-03-05 MX MX2011009188A patent/MX2011009188A/es active IP Right Grant
- 2010-03-05 HU HUE10708924A patent/HUE035166T2/en unknown
- 2010-03-05 JP JP2011553331A patent/JP5840955B2/ja not_active Expired - Fee Related
- 2010-03-05 EP EP10708924.5A patent/EP2406216B1/de not_active Not-in-force
- 2010-03-05 CN CN201310556920.7A patent/CN103641709B/zh not_active Expired - Fee Related
- 2010-03-05 EA EA201190190A patent/EA024266B1/ru not_active IP Right Cessation
- 2010-03-05 ES ES10708924.5T patent/ES2632567T3/es active Active
- 2010-03-08 AR ARP100100694A patent/AR075848A1/es active IP Right Grant
- 2010-03-11 US US12/659,536 patent/US8518985B2/en not_active Expired - Fee Related
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2013
- 2013-07-22 US US13/947,447 patent/US9045390B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010102758A2 (de) | 2010-09-16 |
| AU2010223535A1 (en) | 2011-09-22 |
| US20140031577A1 (en) | 2014-01-30 |
| BRPI1008949A2 (pt) | 2015-09-01 |
| AR075848A1 (es) | 2011-05-04 |
| MX338802B (es) | 2016-05-02 |
| US20100311593A1 (en) | 2010-12-09 |
| KR20110132591A (ko) | 2011-12-08 |
| HUE035166T2 (en) | 2018-05-02 |
| AU2010223535B2 (en) | 2015-09-10 |
| CN103641709B (zh) | 2017-08-25 |
| JP5840955B2 (ja) | 2016-01-06 |
| WO2010102758A3 (de) | 2011-01-20 |
| CN102348684A (zh) | 2012-02-08 |
| CN103641709A (zh) | 2014-03-19 |
| EP2406216B1 (de) | 2017-04-19 |
| EP3153503A1 (de) | 2017-04-12 |
| KR101703633B1 (ko) | 2017-02-07 |
| US8518985B2 (en) | 2013-08-27 |
| EA201190190A1 (ru) | 2012-02-28 |
| CA2754847A1 (en) | 2010-09-16 |
| EP2406216A2 (de) | 2012-01-18 |
| JP2012520242A (ja) | 2012-09-06 |
| PL2406216T3 (pl) | 2017-09-29 |
| CA2754847C (en) | 2017-07-11 |
| MX2011009188A (es) | 2011-09-26 |
| EA024266B1 (ru) | 2016-09-30 |
| ES2632567T3 (es) | 2017-09-14 |
| US9045390B2 (en) | 2015-06-02 |
| US20140213813A9 (en) | 2014-07-31 |
| CN102348684B (zh) | 2014-11-12 |
| BRPI1008949B1 (pt) | 2018-07-10 |
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| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2764 DE 26-12-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |