BRPI1015079A2 - Hidroxitienoquinolonas e compostos relacionados como agentes anti-infecciosos - Google Patents
Hidroxitienoquinolonas e compostos relacionados como agentes anti-infecciososInfo
- Publication number
- BRPI1015079A2 BRPI1015079A2 BRPI1015079-0A BRPI1015079A BRPI1015079A2 BR PI1015079 A2 BRPI1015079 A2 BR PI1015079A2 BR PI1015079 A BRPI1015079 A BR PI1015079A BR PI1015079 A2 BRPI1015079 A2 BR PI1015079A2
- Authority
- BR
- Brazil
- Prior art keywords
- hydroxythienoquinolones
- antiinfectives
- related compounds
- compounds
- Prior art date
Links
- SBMPLNOQELVUTP-UHFFFAOYSA-N 7-oxo-1h-thieno[2,3-h]quinolin-2-one Chemical class C12=NC(O)=CC=C2C=CC2=C1C=CS2=O SBMPLNOQELVUTP-UHFFFAOYSA-N 0.000 title 1
- 230000002924 anti-infective effect Effects 0.000 title 1
- 229960005475 antiinfective agent Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4743—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/16—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16637109P | 2009-04-03 | 2009-04-03 | |
| PCT/US2010/029938 WO2010115184A2 (en) | 2009-04-03 | 2010-04-05 | Hydroxythienoquinolones and related compounds as anti-infective agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1015079A2 true BRPI1015079A2 (pt) | 2015-09-01 |
Family
ID=42826698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1015079-0A BRPI1015079A2 (pt) | 2009-04-03 | 2010-04-05 | Hidroxitienoquinolonas e compostos relacionados como agentes anti-infecciosos |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8173636B2 (pt) |
| EP (1) | EP2414368B1 (pt) |
| JP (1) | JP2012522807A (pt) |
| KR (1) | KR20120004510A (pt) |
| CN (1) | CN102388053A (pt) |
| AU (1) | AU2010232388A1 (pt) |
| BR (1) | BRPI1015079A2 (pt) |
| CA (1) | CA2756701A1 (pt) |
| EA (1) | EA201101451A1 (pt) |
| IL (1) | IL215120A0 (pt) |
| MX (1) | MX2011010434A (pt) |
| NZ (1) | NZ595448A (pt) |
| SG (1) | SG174498A1 (pt) |
| WO (1) | WO2010115184A2 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101263146B (zh) | 2005-07-27 | 2012-12-05 | 艾其林医药公司 | 抗感染试剂8-甲氧基-9h-异噻唑并[5,4-b]喹啉-3,4-二酮及相关化合物 |
| US20130165471A1 (en) * | 2011-12-21 | 2013-06-27 | Achillion Pharmaceuticals Inc. | 2-substituted-thienoquinolones and related compounds as anti-infective agents |
| GB201406486D0 (en) | 2014-04-10 | 2014-05-28 | Redx Pharma Ltd | Antibacterial compounds |
| CN104513238A (zh) * | 2014-12-08 | 2015-04-15 | 深圳华润九新药业有限公司 | 抗菌有机化合物及其制备方法和抗菌药物 |
| EP4483875A3 (en) | 2016-05-10 | 2025-04-02 | C4 Therapeutics, Inc. | Spirocyclic degronimers for target protein degradation |
| CN109641874A (zh) | 2016-05-10 | 2019-04-16 | C4医药公司 | 用于靶蛋白降解的c3-碳连接的戊二酰亚胺降解决定子体 |
| CN109562107A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的杂环降解决定子体 |
| EP3455219A4 (en) | 2016-05-10 | 2019-12-18 | C4 Therapeutics, Inc. | AMINE-RELATED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION |
| WO2018165612A1 (en) | 2017-03-10 | 2018-09-13 | Rutgers, The State University Of New Jersey | Bacterial efflux pump inhibitors |
| CN110770224B (zh) | 2017-03-10 | 2022-11-18 | 罗格斯新泽西州立大学 | 作为外排泵抑制剂的吲哚衍生物 |
| WO2018165614A1 (en) * | 2017-03-10 | 2018-09-13 | Rutgers, The State University Of New Jersey | Bacterial efflux pump inhibitors |
| US11826357B2 (en) | 2017-05-26 | 2023-11-28 | Rutgers, The State University Of New Jersey | Bacterial efflux pump inhibitors |
| EP3641762B1 (en) | 2017-06-20 | 2026-02-18 | C4 Therapeutics, Inc. | N/o-linked degrons and degronimers for protein degradation |
| WO2019005841A1 (en) | 2017-06-26 | 2019-01-03 | Rutgers, The State University Of New Jersey | THERAPEUTIC COMPOUNDS AND METHODS FOR TREATING INFECTION |
| WO2021188586A1 (en) * | 2020-03-16 | 2021-09-23 | Board Of Regents, The University Of Texas System | Method of treating viral infections with hexose type monosaccharides and analogs thereof |
| KR20230093858A (ko) | 2021-12-20 | 2023-06-27 | 삼성전자주식회사 | 화합물, 센서, 센서 내장형 표시 패널 및 전자 장치 |
| US11731970B1 (en) | 2023-03-23 | 2023-08-22 | King Faisal University | Pyrrolo[2,3-b]quinoline compounds as antibacterial agents |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4767762A (en) * | 1985-12-23 | 1988-08-30 | Abbott Laboratories | Tricyclic quinoline and naphthyride antibacterials |
| JPH01160985A (ja) | 1987-12-17 | 1989-06-23 | Otsuka Pharmaceut Co Ltd | ベンゾヘテロ環化合物 |
| JPH01193275A (ja) | 1988-01-28 | 1989-08-03 | Otsuka Pharmaceut Co Ltd | ベンゾヘテロ環化合物 |
| JP2681190B2 (ja) | 1988-04-13 | 1997-11-26 | 塩野義製薬株式会社 | ピリドン系抗菌剤 |
| CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
| US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
| JPH02174784A (ja) | 1988-12-27 | 1990-07-06 | Hokuriku Seiyaku Co Ltd | イソチアゾロキノリン誘導体 |
| JPH02243692A (ja) | 1989-03-16 | 1990-09-27 | Dainippon Pharmaceut Co Ltd | 三環式化合物 |
| JPH02255687A (ja) | 1989-03-27 | 1990-10-16 | Dainippon Pharmaceut Co Ltd | 三環式化合物 |
| FR2645862B1 (fr) * | 1989-04-18 | 1991-07-12 | Esteve Labor Dr | Derives d'isothiazolo-pyrydone azetidinyl substitues, leur preparation et leur application en tant que medicaments |
| JP2787713B2 (ja) | 1989-07-28 | 1998-08-20 | 富山化学工業株式会社 | 新規なイソチアゾローナフチリジンおよびイソチアゾローキノリン誘導体並びにそれらの塩 |
| US5071848A (en) * | 1989-10-23 | 1991-12-10 | Abbott Laboratories | Tricyclic quinoline antineoplastic agents |
| JP3012684B2 (ja) * | 1989-12-08 | 2000-02-28 | 大日本製薬株式会社 | チエノキノリン誘導体、チエノナフチリジン誘導体およびそれらの塩 |
| JP2939280B2 (ja) | 1990-01-10 | 1999-08-25 | 三共株式会社 | フッ素置換メトキシキノロンカルボン酸誘導体 |
| CN1076697A (zh) * | 1992-01-11 | 1993-09-29 | 先灵农业化学品公司 | 二杂环杀菌化合物 |
| NO304832B1 (no) * | 1992-05-27 | 1999-02-22 | Ube Industries | Aminokinolonderivater samt middel mot HIV |
| US5646163A (en) | 1992-10-30 | 1997-07-08 | The Procter & Gamble Company | Quinolone 5-(N-heterosubstituted amino) antimicrobials |
| HUP9901642A3 (en) | 1996-01-31 | 2000-07-28 | Ube Ind Ltd Ube Shi | Remedies or preventives for aids |
| JP3616454B2 (ja) | 1996-04-19 | 2005-02-02 | 栄研化学株式会社 | 生体成分測定用試薬 |
| JPH10130149A (ja) | 1996-07-12 | 1998-05-19 | Sankyo Co Ltd | Ｔｎｆ産生抑制剤 |
| NZ525571A (en) | 2000-12-14 | 2004-09-24 | Procter & Gamble | Antimicrobial quinolones |
| AU2004267052B2 (en) * | 2003-08-12 | 2009-02-05 | Achillion Pharmaceuticals, Inc. | Isothiazoloquinolones and related compounds as anti-infective agents |
| EP1848723B1 (en) * | 2005-02-16 | 2010-12-15 | Achillion Pharmaceuticals, Inc. | New isothiazoloquinolones and related compounds as anti-infective agents |
| CN101263146B (zh) * | 2005-07-27 | 2012-12-05 | 艾其林医药公司 | 抗感染试剂8-甲氧基-9h-异噻唑并[5,4-b]喹啉-3,4-二酮及相关化合物 |
-
2010
- 2010-04-05 WO PCT/US2010/029938 patent/WO2010115184A2/en not_active Ceased
- 2010-04-05 MX MX2011010434A patent/MX2011010434A/es unknown
- 2010-04-05 EA EA201101451A patent/EA201101451A1/ru unknown
- 2010-04-05 CA CA2756701A patent/CA2756701A1/en not_active Abandoned
- 2010-04-05 BR BRPI1015079-0A patent/BRPI1015079A2/pt not_active IP Right Cessation
- 2010-04-05 EP EP10759532.4A patent/EP2414368B1/en not_active Not-in-force
- 2010-04-05 JP JP2012503766A patent/JP2012522807A/ja not_active Withdrawn
- 2010-04-05 SG SG2011068236A patent/SG174498A1/en unknown
- 2010-04-05 US US12/754,057 patent/US8173636B2/en not_active Expired - Fee Related
- 2010-04-05 AU AU2010232388A patent/AU2010232388A1/en not_active Abandoned
- 2010-04-05 CN CN2010800151548A patent/CN102388053A/zh active Pending
- 2010-04-05 NZ NZ595448A patent/NZ595448A/xx not_active IP Right Cessation
- 2010-04-05 KR KR1020117026288A patent/KR20120004510A/ko not_active Abandoned
-
2011
- 2011-09-13 IL IL215120A patent/IL215120A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20120004510A (ko) | 2012-01-12 |
| EP2414368A4 (en) | 2012-09-19 |
| NZ595448A (en) | 2013-01-25 |
| CA2756701A1 (en) | 2010-10-07 |
| AU2010232388A1 (en) | 2011-10-27 |
| US20100256112A1 (en) | 2010-10-07 |
| MX2011010434A (es) | 2012-01-20 |
| CN102388053A (zh) | 2012-03-21 |
| EA201101451A1 (ru) | 2012-03-30 |
| WO2010115184A3 (en) | 2011-03-24 |
| HK1160855A1 (en) | 2012-08-17 |
| EP2414368A2 (en) | 2012-02-08 |
| WO2010115184A2 (en) | 2010-10-07 |
| JP2012522807A (ja) | 2012-09-27 |
| SG174498A1 (en) | 2011-10-28 |
| IL215120A0 (en) | 2011-12-29 |
| US8173636B2 (en) | 2012-05-08 |
| EP2414368B1 (en) | 2013-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |