CA1109076A - Biologically active amides - Google Patents

Biologically active amides

Info

Publication number
CA1109076A
CA1109076A CA270,904A CA270904A CA1109076A CA 1109076 A CA1109076 A CA 1109076A CA 270904 A CA270904 A CA 270904A CA 1109076 A CA1109076 A CA 1109076A
Authority
CA
Canada
Prior art keywords
formula
acid
compound
fluoro
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA270,904A
Other languages
English (en)
French (fr)
Inventor
Eugene Grivsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Application granted granted Critical
Publication of CA1109076A publication Critical patent/CA1109076A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/11—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/09—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an acyclic unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/618—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
CA270,904A 1976-02-03 1977-02-02 Biologically active amides Expired CA1109076A (en)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
GB416976 1976-02-03
GB4170/76 1976-02-03
GB417076 1976-02-03
GB4169/76 1976-02-03
GB4168/76A GB1568401A (en) 1976-02-03 1976-02-03 Biologically active amides
GB4168/76 1976-02-03
US71231876A 1976-08-06 1976-08-06
US71213576A 1976-08-06 1976-08-06
US71213476A 1976-08-06 1976-08-06
US712,135 1976-08-06
US712,134 1976-08-06
US712,318 1976-08-06

Publications (1)

Publication Number Publication Date
CA1109076A true CA1109076A (en) 1981-09-15

Family

ID=27546490

Family Applications (1)

Application Number Title Priority Date Filing Date
CA270,904A Expired CA1109076A (en) 1976-02-03 1977-02-02 Biologically active amides

Country Status (20)

Country Link
JP (1) JPS6056700B2 (de)
AR (1) AR218865A1 (de)
AT (1) AT363926B (de)
BE (1) BE851020A (de)
CA (1) CA1109076A (de)
CH (1) CH634551A5 (de)
CS (2) CS245756B2 (de)
DD (1) DD130349A5 (de)
DE (1) DE2704365C2 (de)
DK (1) DK43177A (de)
FI (1) FI69625C (de)
FR (1) FR2340303A1 (de)
GB (1) GB1568401A (de)
GR (1) GR66474B (de)
HU (1) HU175435B (de)
IE (1) IE44862B1 (de)
IL (1) IL51373A (de)
NL (1) NL7701088A (de)
PL (2) PL119314B1 (de)
SE (2) SE436870B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116877A (en) * 1989-02-02 1992-05-26 Taisho Pharmaceutical Co., Ltd. Pharmaceutical use for cinnamamide derivatives
DE19931116A1 (de) * 1999-07-06 2001-01-11 Bayer Ag Verfahren zur Herstellung von Phenethylaminen und neue chemische Verbindungen
CN104513172B (zh) * 2013-09-30 2018-02-02 天士力医药集团股份有限公司 含有三氟甲基的酰胺生物碱、制备方法及其药物用途
CN104432097B (zh) * 2014-12-16 2016-08-17 广州渔夫堡医药科技有限公司 一种缓解体力疲劳的天然增补剂

Also Published As

Publication number Publication date
SE8300432L (sv) 1983-01-28
CS245758B2 (en) 1986-10-16
IE44862B1 (en) 1982-04-21
PL119716B1 (en) 1982-01-30
SE436870B (sv) 1985-01-28
FI770365A7 (de) 1977-08-04
PL119314B1 (en) 1981-12-31
PL195740A1 (pl) 1979-05-07
SE8300432D0 (sv) 1983-01-28
JPS6056700B2 (ja) 1985-12-11
CH634551A5 (en) 1983-02-15
IL51373A (en) 1981-12-31
DD130349A5 (de) 1978-03-22
GR66474B (de) 1981-03-23
JPS52116437A (en) 1977-09-29
NL7701088A (nl) 1977-08-05
IL51373A0 (en) 1977-04-29
IE44862L (en) 1977-08-03
DE2704365A1 (de) 1977-08-04
CS245756B2 (en) 1986-10-16
FI69625C (fi) 1986-03-10
ATA65277A (de) 1981-02-15
FR2340303A1 (fr) 1977-09-02
FI69625B (fi) 1985-11-29
AT363926B (de) 1981-09-10
BE851020A (fr) 1977-08-02
FR2340303B1 (de) 1979-04-13
DE2704365C2 (de) 1986-03-20
DK43177A (da) 1977-08-04
GB1568401A (en) 1980-05-29
AR218865A1 (es) 1980-07-15
SE7701107L (sv) 1977-08-04
HU175435B (hu) 1980-07-28

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Legal Events

Date Code Title Description
MKEX Expiry