CH368795A - Verfahren zur Herstellung von in 4-Stellung substituierten Steroiden - Google Patents

Verfahren zur Herstellung von in 4-Stellung substituierten Steroiden

Info

Publication number: CH368795A
Authority: CH; Switzerland
Prior art keywords: epoxy; keto; steroid; dione; melting point
Prior art date: 1956-03-29

Application number

CH3878356A

Other languages

German (de)

English (en)

Inventor

Camerino Bruno

Patelli Bianca

Vercellone Alberto

Original Assignee

Farmaceutici Italia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1956-03-29

Filing date

1956-10-22

Publication date

1963-04-30

1956-10-22 Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia

1963-04-30 Publication of CH368795A publication Critical patent/CH368795A/de

Links

238000000034 method Methods 0.000 title claims description 14
150000003431 steroids Chemical group 0.000 title claims description 4
238000002360 preparation method Methods 0.000 title description 3
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims description 12
WTEOIRVLGSZEPR-UHFFFAOYSA-N boron trifluoride Chemical compound FB(F)F WTEOIRVLGSZEPR-UHFFFAOYSA-N 0.000 claims description 6
239000003960 organic solvent Substances 0.000 claims description 4
229910015900 BF3 Inorganic materials 0.000 claims description 3
239000000203 mixture Substances 0.000 claims description 2
239000004593 Epoxy Substances 0.000 claims 3
229920000647 polyepoxide Polymers 0.000 claims 1
238000002844 melting Methods 0.000 description 10
230000008018 melting Effects 0.000 description 10
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
KZMGYPLQYOPHEL-UHFFFAOYSA-N Boron trifluoride etherate Chemical compound FB(F)F.CCOCC KZMGYPLQYOPHEL-UHFFFAOYSA-N 0.000 description 2
UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
230000000397 acetylating effect Effects 0.000 description 2
239000002253 acid Substances 0.000 description 2
229930194542 Keto Natural products 0.000 description 1
230000002378 acidificating effect Effects 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
150000002085 enols Chemical group 0.000 description 1
229910052500 inorganic mineral Inorganic materials 0.000 description 1
125000000468 ketone group Chemical group 0.000 description 1
239000011707 mineral Substances 0.000 description 1
235000010755 mineral Nutrition 0.000 description 1
238000001953 recrystallisation Methods 0.000 description 1
229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
235000017557 sodium bicarbonate Nutrition 0.000 description 1
239000007858 starting material Substances 0.000 description 1
239000000126 substance Substances 0.000 description 1
QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)

CH3878356A 1956-03-29 1956-10-22 Verfahren zur Herstellung von in 4-Stellung substituierten Steroiden CH368795A (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT479656		1956-03-29

Publications (1)

Publication Number	Publication Date
CH368795A true CH368795A (de)	1963-04-30

Family

ID=11113844

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH3878356A CH368795A (de)	1956-03-29	1956-10-22	Verfahren zur Herstellung von in 4-Stellung substituierten Steroiden

Country Status (2)

Country	Link
CH (1)	CH368795A (es)
ES (1)	ES231618A2 (es)

1956
- 1956-10-22 CH CH3878356A patent/CH368795A/de unknown
- 1956-10-29 ES ES0231618A patent/ES231618A2/es not_active Expired

Also Published As

Publication number	Publication date
ES231618A2 (es)	1957-05-16

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