CH617964A5 - Process for the preparation of new aminocyclitol antibiotics - Google Patents

Process for the preparation of new aminocyclitol antibiotics Download PDF

Info

Publication number
CH617964A5
CH617964A5 CH193476A CH193476A CH617964A5 CH 617964 A5 CH617964 A5 CH 617964A5 CH 193476 A CH193476 A CH 193476A CH 193476 A CH193476 A CH 193476A CH 617964 A5 CH617964 A5 CH 617964A5
Authority
CH
Switzerland
Prior art keywords
methyl
amino
methylamino
deoxy
aminocyclitol
Prior art date
Application number
CH193476A
Other languages
English (en)
French (fr)
Inventor
Sol Jacob Daum
Robert Lagrone Clarke
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/550,273 external-priority patent/US3972930A/en
Priority claimed from US05/615,593 external-priority patent/US3982996A/en
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of CH617964A5 publication Critical patent/CH617964A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/497—Saturated compounds containing a keto group being part of a ring containing hydroxy groups a keto group being part of a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CH193476A 1975-02-18 1976-02-17 Process for the preparation of new aminocyclitol antibiotics CH617964A5 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/550,273 US3972930A (en) 1975-02-18 1975-02-18 Aminocyclitol antibiotics
US05/615,593 US3982996A (en) 1975-09-22 1975-09-22 Process for preparing aminocyclitol antibiotics

Publications (1)

Publication Number Publication Date
CH617964A5 true CH617964A5 (en) 1980-06-30

Family

ID=27069389

Family Applications (3)

Application Number Title Priority Date Filing Date
CH193476A CH617964A5 (en) 1975-02-18 1976-02-17 Process for the preparation of new aminocyclitol antibiotics
CH1126678A CH618214A5 (en) 1975-02-18 1978-11-01 Process for the preparation of aminocyclitol antibiotics
CH1126778A CH618215A5 (en) 1975-02-18 1978-11-01 Process for the preparation of aminocyclitol antibiotics

Family Applications After (2)

Application Number Title Priority Date Filing Date
CH1126678A CH618214A5 (en) 1975-02-18 1978-11-01 Process for the preparation of aminocyclitol antibiotics
CH1126778A CH618215A5 (en) 1975-02-18 1978-11-01 Process for the preparation of aminocyclitol antibiotics

Country Status (21)

Country Link
JP (1) JPS51108041A (da)
AR (3) AR221027A1 (da)
AU (1) AU503105B2 (da)
CA (1) CA1061731A (da)
CH (3) CH617964A5 (da)
DE (1) DE2606517A1 (da)
DK (1) DK143111C (da)
EG (1) EG12994A (da)
ES (1) ES445274A1 (da)
FI (1) FI56026C (da)
FR (1) FR2301265A1 (da)
GB (1) GB1529376A (da)
GR (1) GR60050B (da)
IE (1) IE42807B1 (da)
IL (1) IL49053A (da)
IN (2) IN147046B (da)
NL (1) NL7601655A (da)
NO (3) NO147308C (da)
NZ (1) NZ180036A (da)
PT (1) PT64816B (da)
SE (2) SE7601810L (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE476970A (da) * 1946-10-24
JP5160419B2 (ja) 2006-06-02 2013-03-13 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 新規アミノグリコシド系抗生物質

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH606434A5 (da) * 1973-08-06 1978-10-31 Scherico Ltd

Also Published As

Publication number Publication date
PT64816B (en) 1978-07-03
FR2301265A1 (fr) 1976-09-17
DK143111B (da) 1981-03-30
NO146811B (no) 1982-09-06
NO803185L (no) 1976-08-19
NO148298B (no) 1983-06-06
NO760472L (da) 1976-08-19
IE42807B1 (en) 1980-10-22
JPS51108041A (da) 1976-09-25
IN147046B (da) 1979-10-27
NO146811C (no) 1982-12-15
AR221027A1 (es) 1980-12-30
PT64816A (en) 1976-03-01
GB1529376A (en) 1978-10-18
NO820574L (no) 1976-08-19
EG12994A (en) 1980-07-31
IE42807L (en) 1976-08-18
NO147308B (no) 1982-12-06
NL7601655A (nl) 1976-08-20
NZ180036A (en) 1979-10-25
GR60050B (en) 1978-04-04
DE2606517A1 (de) 1976-08-26
SE8007540L (sv) 1980-10-27
DK143111C (da) 1981-11-16
AU1117776A (en) 1977-08-25
IL49053A (en) 1979-11-30
CA1061731A (en) 1979-09-04
SE7601810L (sv) 1976-08-19
FI56026B (fi) 1979-07-31
FI56026C (fi) 1979-11-12
AR217417A1 (es) 1980-03-31
DK63176A (da) 1976-08-19
NO148298C (no) 1983-09-14
ES445274A1 (es) 1977-06-16
AR227266A1 (es) 1982-10-15
IL49053A0 (en) 1976-04-30
CH618215A5 (en) 1980-07-15
FR2301265B1 (da) 1979-05-25
AU503105B2 (en) 1979-08-23
CH618214A5 (en) 1980-07-15
IN149240B (da) 1981-10-10
FI760387A7 (da) 1976-08-19
NO147308C (no) 1983-03-16

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Legal Events

Date Code Title Description
PL Patent ceased
PL Patent ceased