CH646950A5 - Carbamatderivate von n-mercaptoacyl-hydroxyprolinen und deren salze und ihre verwendung in arzneimitteln gegen hypertonie. - Google Patents

Carbamatderivate von n-mercaptoacyl-hydroxyprolinen und deren salze und ihre verwendung in arzneimitteln gegen hypertonie. Download PDF

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Publication number
CH646950A5
CH646950A5 CH24080A CH24080A CH646950A5 CH 646950 A5 CH646950 A5 CH 646950A5 CH 24080 A CH24080 A CH 24080A CH 24080 A CH24080 A CH 24080A CH 646950 A5 CH646950 A5 CH 646950A5
Authority
CH
Switzerland
Prior art keywords
methyl
proline
carbonyl
lower alkyl
oxy
Prior art date
Application number
CH24080A
Other languages
German (de)
English (en)
Inventor
John Krapcho
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of CH646950A5 publication Critical patent/CH646950A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CH24080A 1979-01-15 1980-01-11 Carbamatderivate von n-mercaptoacyl-hydroxyprolinen und deren salze und ihre verwendung in arzneimitteln gegen hypertonie. CH646950A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US317879A 1979-01-15 1979-01-15

Publications (1)

Publication Number Publication Date
CH646950A5 true CH646950A5 (de) 1984-12-28

Family

ID=21704564

Family Applications (2)

Application Number Title Priority Date Filing Date
CH24080A CH646950A5 (de) 1979-01-15 1980-01-11 Carbamatderivate von n-mercaptoacyl-hydroxyprolinen und deren salze und ihre verwendung in arzneimitteln gegen hypertonie.
CH619383A CH646690A5 (de) 1979-01-15 1983-11-17 Carbamatderivate von hydroxyprolinen.

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH619383A CH646690A5 (de) 1979-01-15 1983-11-17 Carbamatderivate von hydroxyprolinen.

Country Status (21)

Country Link
JP (2) JPS5598161A (fr)
AT (1) AT364377B (fr)
AU (1) AU526767B2 (fr)
BE (1) BE881153A (fr)
CA (1) CA1138452A (fr)
CH (2) CH646950A5 (fr)
DE (1) DE3001113A1 (fr)
DK (1) DK14980A (fr)
FR (1) FR2446281A1 (fr)
GB (2) GB2040937B (fr)
GR (1) GR73002B (fr)
HU (2) HU182778B (fr)
IE (1) IE49357B1 (fr)
IT (1) IT1140505B (fr)
LU (1) LU82082A1 (fr)
NL (1) NL8000206A (fr)
NO (1) NO800077L (fr)
NZ (1) NZ192522A (fr)
PH (2) PH14946A (fr)
SE (1) SE8000298L (fr)
ZA (1) ZA8035B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316905A (en) * 1980-07-01 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of various 4-substituted prolines
CA1258853A (fr) * 1982-04-30 1989-08-29 Rudiger D. Haugwitz Derives de substitution de 4-phenoxy-prolines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4052511A (en) * 1976-02-13 1977-10-04 E. R. Squibb & Sons, Inc. Carboxyacylproline derivatives

Also Published As

Publication number Publication date
ZA8035B (en) 1980-12-31
PH14946A (en) 1982-02-02
JPS5598161A (en) 1980-07-25
JPH0378378B2 (fr) 1991-12-13
SE8000298L (sv) 1980-07-16
GB2040937B (en) 1982-11-24
NO800077L (no) 1980-07-16
IE800048L (en) 1980-07-15
HU179621B (en) 1982-11-29
AT364377B (de) 1981-10-12
JPH0125744B2 (fr) 1989-05-19
HU182778B (en) 1984-03-28
LU82082A1 (fr) 1980-04-23
FR2446281B1 (fr) 1984-01-20
ATA19080A (de) 1981-03-15
IT8019209A0 (it) 1980-01-14
BE881153A (fr) 1980-07-15
GR73002B (fr) 1984-01-24
DE3001113A1 (de) 1980-07-24
IT1140505B (it) 1986-10-01
GB2040937A (en) 1980-09-03
GB2088875B (en) 1983-06-08
JPH01301656A (ja) 1989-12-05
CA1138452A (fr) 1982-12-28
DK14980A (da) 1980-07-16
GB2088875A (en) 1982-06-16
IE49357B1 (en) 1985-09-18
FR2446281A1 (fr) 1980-08-08
PH15318A (en) 1982-11-18
NL8000206A (nl) 1980-07-17
NZ192522A (en) 1982-06-29
AU526767B2 (en) 1983-01-27
AU5432780A (en) 1980-07-24
CH646690A5 (de) 1984-12-14

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