CL2007002733A1 - Compuestos derivados de 2-aril-6-fenil-imidazo[1,2-a]piridinas; procedimiento de obtencion de los compuestos; composicion farmaceutica; y uso para el tratamiento y prevencion de enfermedades neurodegenerativas, osteoporosis y cancer. - Google Patents

Compuestos derivados de 2-aril-6-fenil-imidazo[1,2-a]piridinas; procedimiento de obtencion de los compuestos; composicion farmaceutica; y uso para el tratamiento y prevencion de enfermedades neurodegenerativas, osteoporosis y cancer.

Info

Publication number: CL2007002733A1
Authority: CL; Chile
Prior art keywords: compounds; piridines; aril; imidazo; osteoporosis
Prior art date: 2006-09-22

Application number

CL200702733A

Other languages

English (en)

Inventor

Garcia Antonio Lardeno Almario

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-09-22

Filing date

2007-09-21

Publication date

2008-04-11

2007-09-21 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2008-04-11 Publication of CL2007002733A1 publication Critical patent/CL2007002733A1/es

Links

150000001875 compounds Chemical class 0.000 title 2
206010028980 Neoplasm Diseases 0.000 title 1
208000001132 Osteoporosis Diseases 0.000 title 1
201000011510 cancer Diseases 0.000 title 1
208000015122 neurodegenerative disease Diseases 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
230000002265 prevention Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Psychology (AREA)
Addiction (AREA)
Transplantation (AREA)
Hospice & Palliative Care (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

CL200702733A 2006-09-22 2007-09-21 Compuestos derivados de 2-aril-6-fenil-imidazo[1,2-a]piridinas; procedimiento de obtencion de los compuestos; composicion farmaceutica; y uso para el tratamiento y prevencion de enfermedades neurodegenerativas, osteoporosis y cancer. CL2007002733A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0608350A FR2906250B1 (fr)	2006-09-22	2006-09-22	Derives de 2-aryl-6phenyl-imidazo(1,2-a) pyridines, leur preparation et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
CL2007002733A1 true CL2007002733A1 (es)	2008-04-11

Family

ID=37841968

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CL200702733A CL2007002733A1 (es)	2006-09-22	2007-09-21	Compuestos derivados de 2-aril-6-fenil-imidazo[1,2-a]piridinas; procedimiento de obtencion de los compuestos; composicion farmaceutica; y uso para el tratamiento y prevencion de enfermedades neurodegenerativas, osteoporosis y cancer.

Country Status (43)

Country	Link
US (1)	US7915284B2 (es)
EP (1)	EP2069342B1 (es)
JP (1)	JP5336378B2 (es)
KR (1)	KR101470039B1 (es)
CN (1)	CN101516881B (es)
AR (1)	AR062897A1 (es)
AT (1)	ATE467633T1 (es)
AU (1)	AU2007298856B2 (es)
BR (1)	BRPI0718517A2 (es)
CA (1)	CA2662848C (es)
CL (1)	CL2007002733A1 (es)
CO (1)	CO6160308A2 (es)
CR (1)	CR10643A (es)
CY (1)	CY1110232T1 (es)
DE (1)	DE602007006525D1 (es)
DK (1)	DK2069342T3 (es)
EA (1)	EA017442B1 (es)
ES (1)	ES2345016T3 (es)
FR (1)	FR2906250B1 (es)
GT (1)	GT200900049A (es)
HN (1)	HN2009000502A (es)
HR (1)	HRP20100408T1 (es)
IL (1)	IL197352A (es)
JO (1)	JO2643B1 (es)
MA (1)	MA30792B1 (es)
ME (1)	ME00615B (es)
MX (1)	MX2009002802A (es)
MY (1)	MY145603A (es)
NI (1)	NI200900037A (es)
NO (1)	NO20091562L (es)
NZ (1)	NZ575337A (es)
PE (1)	PE20080671A1 (es)
PL (1)	PL2069342T3 (es)
PT (1)	PT2069342E (es)
RS (1)	RS51412B (es)
SI (1)	SI2069342T1 (es)
SV (1)	SV2009003193A (es)
TN (1)	TN2009000081A1 (es)
TW (1)	TWI381837B (es)
UA (1)	UA95976C2 (es)
UY (1)	UY30603A1 (es)
WO (1)	WO2008034974A1 (es)
ZA (1)	ZA200901551B (es)

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FR2928921B1 (fr) *	2008-03-21	2010-04-23	Sanofi Aventis	Derives polysubstitues de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines, leur preparation et leur application en therapeutique
FR2928923B1 (fr) *	2008-03-21	2010-04-23	Sanofi Aventis	Derives polysubstitues de 2-heteroaryl-6-phenyl-imidazo °1,2-a!pyridines, leur preparation et leur application en therapeutiques
FR2928922B1 (fr) *	2008-03-21	2010-04-23	Sanofi Aventis	Derives de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines polysubstitues, leur preparation et leur application en therapeutique
FR2928924B1 (fr)	2008-03-21	2010-04-23	Sanofi Aventis	Derives polysubstitues de 6-heteroaryle-imidazo°1,2-a! pyridines, leur preparation et leur application en therapeutique
FR2933609B1 (fr) *	2008-07-10	2010-08-27	Fournier Lab Sa	Utilisation de derives d'indole comme activateurs de nurr-1, pour le traitement de la maladie de parkinson.
FR2950344B1 (fr) *	2009-09-18	2011-11-25	Sanofi Aventis	Derives de 5-phenyl-pyrazolopyridine, leur preparation et leur aplication en therapeutique.
FR2950345B1 (fr) *	2009-09-18	2011-09-23	Sanofi Aventis	Derives acetyleniques de 5-phenyl-pyrazolopyridine, leur preparation et leur application en therapeutique
FR2953520B1 (fr)	2009-12-04	2011-11-25	Sanofi Aventis	Derives de diphenyl-pyrazolopyridines, leur preparation et leur application en therapeutique
KR101735975B1 (ko) *	2012-11-29	2017-05-15	에프. 호프만-라 로슈 아게	이미다조피리딘 유도체
TWI644899B (zh)	2013-02-04	2018-12-21	健生藥品公司	Ｆｌａｐ調節劑
US9079866B2 (en)	2013-02-04	2015-07-14	Janssen Pharmaceutica Nv	Flap modulators
DK3027615T3 (da) *	2013-08-02	2021-10-25	Pasteur Institut Korea	Antiinfektionsforbindelser
TWI698435B (zh)	2015-04-10	2020-07-11	英屬開曼群島商百濟神州有限公司	作為吲哚胺２,３-二加氧酶和/或色氨酸２,３-二加氧酶抑制劑之新穎之５或８-取代之咪唑並［１，５－ａ］吡啶
WO2017070089A1 (en)	2015-10-19	2017-04-27	Incyte Corporation	Heterocyclic compounds as immunomodulators
SG10202004618TA (en)	2015-11-19	2020-06-29	Incyte Corp	Heterocyclic compounds as immunomodulators
MA44075A (fr)	2015-12-17	2021-05-19	Incyte Corp	Dérivés de n-phényl-pyridine-2-carboxamide et leur utilisation en tant que modulateurs des interactions protéine/protéine pd-1/pd-l1
AU2016379372A1 (en)	2015-12-22	2018-08-02	Incyte Corporation	Heterocyclic compounds as immunomodulators
AR108396A1 (es)	2016-05-06	2018-08-15	Incyte Corp	Compuestos heterocíclicos como inmunomoduladores
WO2017205464A1 (en)	2016-05-26	2017-11-30	Incyte Corporation	Heterocyclic compounds as immunomodulators
HUE060256T2 (hu)	2016-06-20	2023-02-28	Incyte Corp	Heterociklusos vegyületek mint immunmodulátorok
EP3484866B1 (en)	2016-07-14	2022-09-07	Incyte Corporation	Heterocyclic compounds as immunomodulators
WO2018044783A1 (en)	2016-08-29	2018-03-08	Incyte Corporation	Heterocyclic compounds as immunomodulators
US10882856B2 (en)	2016-09-24	2021-01-05	Beigene, Ltd.	5 or 8-substituted imidazo [1,5-a] pyridines as selective inhibitors of indoleamine and/or tryptophane 2,3-dioxygenases
LT3558990T (lt)	2016-12-22	2022-12-27	Incyte Corporation	Tetrahidroimidazo[4,5-c]piridino dariniai kaip pd-l1 internalizavimo induktoriai
WO2018119221A1 (en)	2016-12-22	2018-06-28	Incyte Corporation	Pyridine derivatives as immunomodulators
ES2874756T3 (es)	2016-12-22	2021-11-05	Incyte Corp	Derivados de triazolo[1,5-A]piridina como inmunomoduladores
US20180179202A1 (en)	2016-12-22	2018-06-28	Incyte Corporation	Heterocyclic compounds as immunomodulators
JP7101678B2 (ja)	2016-12-22	2022-07-15	インサイト・コーポレイション	免疫調節剤としての複素環式化合物
CN111386114A (zh)	2017-11-25	2020-07-07	百济神州有限公司	作为吲哚胺2,3-双加氧酶的选择性抑制剂的新颖苯并咪唑
SMT202500157T1 (it)	2018-03-30	2025-05-12	Incyte Corp	Composti eterociclici come immunomodulatori
HUE061503T2 (hu)	2018-05-11	2023-07-28	Incyte Corp	Tetrahidro-imidazo[4,5-C]piridin-származékok mint PD-L1 immunmodulátorok
JP7665593B2 (ja)	2019-08-09	2025-04-21	インサイト・コーポレイション	Ｐｄ－１／ｐｄ－ｌ１阻害剤の塩
PE20221038A1 (es)	2019-09-30	2022-06-17	Incyte Corp	Compuestos de pirido[3,2-d] pirimidina como inmunomoduladores
CA3160131A1 (en)	2019-11-11	2021-05-20	Incyte Corporation	Salts and crystalline forms of a pd-1/pd-l1 inhibitor
CN114728071B (zh) *	2019-11-13	2024-12-06	新旭生技股份有限公司	用于降解tau蛋白聚集体的化合物及其用途
TW202233615A (zh)	2020-11-06	2022-09-01	美商英塞特公司	Ｐｄ—１／ｐｄ—ｌ１抑制劑之結晶形式
WO2022099018A1 (en)	2020-11-06	2022-05-12	Incyte Corporation	Process of preparing a pd-1/pd-l1 inhibitor
CR20230230A (es)	2020-11-06	2023-07-27	Incyte Corp	Proceso para hacer un inhibidor de pd-1/pdl1 y sales y formas cristalinas del mismo

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WO2001074813A2 (en) *	2000-03-31	2001-10-11	Ortho Mcneil Pharmaceutical, Inc.	METHOD FOR USING 2- OR 3-ARYL SUBSTITUTED IMIDAZO[1,2-a] PYRIDINES AS H3 ANTAGONISTS
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MY133311A (en) *	2002-09-19	2007-11-30	Schering Corp	Novel imidazopyridines as cyclin dependent kinase inhibitors
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WO2005086808A2 (en) *	2004-03-08	2005-09-22	The University Of North Carolina At Chapel Hill	NOVEL DICATIONIC IMIDAZO[1,2-a]PYRIDINES AND 5,6,7,8-TETRAHYDRO-IMIDAZO[1,2a]PYRIDINES AS ANTIPROTOZOAL AGENTS

2006
- 2006-09-22 FR FR0608350A patent/FR2906250B1/fr active Active
2007
- 2007-09-13 TW TW096134253A patent/TWI381837B/zh not_active IP Right Cessation
- 2007-09-19 WO PCT/FR2007/001517 patent/WO2008034974A1/fr not_active Ceased
- 2007-09-19 RS RSP-2010/0356A patent/RS51412B/sr unknown
- 2007-09-19 AU AU2007298856A patent/AU2007298856B2/en not_active Ceased
- 2007-09-19 EA EA200970311A patent/EA017442B1/ru not_active IP Right Cessation
- 2007-09-19 HR HR20100408T patent/HRP20100408T1/hr unknown
- 2007-09-19 BR BRPI0718517-0A patent/BRPI0718517A2/pt active Search and Examination
- 2007-09-19 CA CA2662848A patent/CA2662848C/fr not_active Expired - Fee Related
- 2007-09-19 DE DE602007006525T patent/DE602007006525D1/de active Active
- 2007-09-19 CN CN2007800352403A patent/CN101516881B/zh not_active Expired - Fee Related
- 2007-09-19 MX MX2009002802A patent/MX2009002802A/es active IP Right Grant
- 2007-09-19 KR KR1020097005741A patent/KR101470039B1/ko not_active Expired - Fee Related
- 2007-09-19 DK DK07848251.0T patent/DK2069342T3/da active
- 2007-09-19 UA UAA200903928A patent/UA95976C2/ru unknown
- 2007-09-19 JP JP2009528752A patent/JP5336378B2/ja not_active Expired - Fee Related
- 2007-09-19 AT AT07848251T patent/ATE467633T1/de active
- 2007-09-19 ES ES07848251T patent/ES2345016T3/es active Active
- 2007-09-19 MY MYPI20091157A patent/MY145603A/en unknown
- 2007-09-19 SI SI200730316T patent/SI2069342T1/sl unknown
- 2007-09-19 EP EP07848251A patent/EP2069342B1/fr active Active
- 2007-09-19 PL PL07848251T patent/PL2069342T3/pl unknown
- 2007-09-19 PT PT07848251T patent/PT2069342E/pt unknown
- 2007-09-19 AR ARP070104136A patent/AR062897A1/es not_active Application Discontinuation
- 2007-09-19 ZA ZA200901551A patent/ZA200901551B/xx unknown
- 2007-09-19 ME MEP-2009-107A patent/ME00615B/me unknown
- 2007-09-19 NZ NZ575337A patent/NZ575337A/en not_active IP Right Cessation
- 2007-09-20 JO JO2007401A patent/JO2643B1/en active
- 2007-09-20 PE PE2007001266A patent/PE20080671A1/es not_active Application Discontinuation
- 2007-09-21 CL CL200702733A patent/CL2007002733A1/es unknown
- 2007-09-21 UY UY30603A patent/UY30603A1/es not_active Application Discontinuation
2009
- 2009-02-26 CR CR10643A patent/CR10643A/es unknown
- 2009-03-02 IL IL197352A patent/IL197352A/en not_active IP Right Cessation
- 2009-03-05 GT GT200900049A patent/GT200900049A/es unknown
- 2009-03-10 TN TN2009000081A patent/TN2009000081A1/fr unknown
- 2009-03-18 HN HN2009000502A patent/HN2009000502A/es unknown
- 2009-03-19 US US12/407,449 patent/US7915284B2/en not_active Expired - Fee Related
- 2009-03-19 CO CO09028759A patent/CO6160308A2/es unknown
- 2009-03-19 SV SV2009003193A patent/SV2009003193A/es active IP Right Grant
- 2009-03-19 NI NI200900037A patent/NI200900037A/es unknown
- 2009-04-16 MA MA31788A patent/MA30792B1/fr unknown
- 2009-04-20 NO NO20091562A patent/NO20091562L/no not_active Application Discontinuation
2010
- 2010-07-20 CY CY20101100678T patent/CY1110232T1/el unknown

Also Published As

Publication number	Publication date
CA2662848A1 (fr)	2008-03-27
PE20080671A1 (es)	2008-07-14
SI2069342T1 (sl)	2010-09-30
TWI381837B (zh)	2013-01-11
RS51412B (sr)	2011-02-28
ZA200901551B (en)	2010-06-30
JP5336378B2 (ja)	2013-11-06
US20090253735A1 (en)	2009-10-08
EP2069342B1 (fr)	2010-05-12
CR10643A (es)	2009-04-29
KR101470039B1 (ko)	2014-12-05
CA2662848C (fr)	2014-12-23
IL197352A0 (en)	2009-12-24
MEP10709A (en)	2011-12-20
NO20091562L (no)	2009-04-20
AU2007298856A1 (en)	2008-03-27
EP2069342A1 (fr)	2009-06-17
SV2009003193A (es)	2010-02-01
CN101516881A (zh)	2009-08-26
HN2009000502A (es)	2011-07-11
ME00615B (me)	2011-12-20
JO2643B1 (en)	2012-06-17
UA95976C2 (en)	2011-09-26
HRP20100408T1 (hr)	2010-09-30
US7915284B2 (en)	2011-03-29
ATE467633T1 (de)	2010-05-15
PT2069342E (pt)	2010-07-19
UY30603A1 (es)	2008-05-02
AU2007298856B2 (en)	2012-08-09
ES2345016T3 (es)	2010-09-13
DK2069342T3 (da)	2010-08-23
EA200970311A1 (ru)	2009-08-28
FR2906250A1 (fr)	2008-03-28
KR20090054449A (ko)	2009-05-29
PL2069342T3 (pl)	2010-10-29
CN101516881B (zh)	2012-07-18
CY1110232T1 (el)	2015-01-14
GT200900049A (es)	2010-03-04
FR2906250B1 (fr)	2008-10-31
IL197352A (en)	2014-11-30
DE602007006525D1 (de)	2010-06-24
MY145603A (en)	2012-03-15
WO2008034974A1 (fr)	2008-03-27
MA30792B1 (fr)	2009-10-01
JP2010504309A (ja)	2010-02-12
MX2009002802A (es)	2009-04-01
TW200833329A (en)	2008-08-16
EA017442B1 (ru)	2012-12-28
HK1135388A1 (en)	2010-06-04
NZ575337A (en)	2011-12-22
NI200900037A (es)	2014-02-20
BRPI0718517A2 (pt)	2013-11-19
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TN2009000081A1 (en)	2010-08-19
CO6160308A2 (es)	2010-05-20

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