BRPI0821004A2 - Composto derivado de aminopirazol, composição farmacêutica que o contem e uso deste - Google Patents
Composto derivado de aminopirazol, composição farmacêutica que o contem e uso desteInfo
- Publication number
- BRPI0821004A2 BRPI0821004A2 BRPI0821004-7A BRPI0821004A BRPI0821004A2 BR PI0821004 A2 BRPI0821004 A2 BR PI0821004A2 BR PI0821004 A BRPI0821004 A BR PI0821004A BR PI0821004 A2 BRPI0821004 A2 BR PI0821004A2
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- composition containing
- derivative compound
- aminopyrazole derivative
- aminopyrazole
- Prior art date
Links
- -1 Aminopyrazole derivative compound Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- AIDS & HIV (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2007055111 | 2007-12-14 | ||
| IB2008053648 | 2008-09-10 | ||
| PCT/IB2008/055251 WO2009077954A1 (en) | 2007-12-14 | 2008-12-12 | Aminopyrazole derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0821004A2 true BRPI0821004A2 (pt) | 2015-06-16 |
| BRPI0821004A8 BRPI0821004A8 (pt) | 2017-12-26 |
Family
ID=40456559
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0821004A BRPI0821004A8 (pt) | 2007-12-14 | 2008-12-12 | Composto derivado de aminopirazol, composição farmacêutica que o contem e uso deste |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8288419B2 (pt) |
| EP (1) | EP2242743B1 (pt) |
| JP (1) | JP5435744B2 (pt) |
| KR (1) | KR101622413B1 (pt) |
| CN (1) | CN101903353B (pt) |
| AR (1) | AR069650A1 (pt) |
| BR (1) | BRPI0821004A8 (pt) |
| CA (1) | CA2706836C (pt) |
| CY (1) | CY1114793T1 (pt) |
| DK (1) | DK2242743T3 (pt) |
| ES (1) | ES2432059T3 (pt) |
| HR (1) | HRP20131105T1 (pt) |
| IL (1) | IL206296A (pt) |
| MA (1) | MA31988B1 (pt) |
| MX (1) | MX2010005827A (pt) |
| MY (1) | MY153921A (pt) |
| NZ (1) | NZ586776A (pt) |
| PL (1) | PL2242743T3 (pt) |
| PT (1) | PT2242743E (pt) |
| RU (1) | RU2489426C2 (pt) |
| SI (1) | SI2242743T1 (pt) |
| TW (1) | TWI430795B (pt) |
| WO (1) | WO2009077954A1 (pt) |
| ZA (1) | ZA201004939B (pt) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2225231T3 (da) | 2007-12-18 | 2011-10-17 | Actelion Pharmaceuticals Ltd | Aminotriazolderivater som alx-agonister |
| KR101724765B1 (ko) | 2009-05-18 | 2017-04-07 | 액테리온 파마슈티칼 리미티드 | Ａｌｘ 수용체 및/또는 ｆｐｒｌ2 아고니스트로서의 브릿지 스피로［2.4］헵탄 유도체 |
| JP5095035B2 (ja) | 2009-06-09 | 2012-12-12 | アクテリオン ファーマシューティカルズ リミテッド | フッ素化アミノトリアゾール誘導体 |
| US8674111B2 (en) | 2009-06-12 | 2014-03-18 | Actelion Pharmaceuticals Ltd. | Oxazole and thiazole derivatives as ALX receptor agonists |
| EA201290957A1 (ru) | 2010-04-07 | 2013-04-30 | Ф.Хоффманн-Ля Рош Аг | Пиразол-4-илгетероциклилкарбоксамидные соединения и способы их применения |
| CA2814826C (en) | 2010-11-17 | 2019-02-12 | Actelion Pharmaceuticals Ltd | Bridged spiro[2.4]heptane ester derivatives |
| KR101847672B1 (ko) | 2010-12-07 | 2018-04-10 | 이도르시아 파마슈티컬스 리미티드 | Alx 수용체 작용제로서의 히드록실화 아미노트리아졸 유도체 |
| CA2816376C (en) | 2010-12-07 | 2018-11-20 | Actelion Pharmaceuticals Ltd | Oxazolyl-methylether derivatives as alx receptor agonists |
| WO2012110986A1 (en) | 2011-02-18 | 2012-08-23 | Actelion Pharmaceuticals Ltd | Novel pyrazole and imidazole derivatives useful as orexin antagonists |
| BR112013028895A2 (pt) | 2011-05-10 | 2016-08-09 | Bayer Ip Gmbh | (tio)carbonilamidinas bicíclicas |
| CA2845191A1 (en) | 2011-09-27 | 2013-04-04 | F. Hoffmann-La Roche Ag | Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use |
| DE102011055815A1 (de) | 2011-11-29 | 2013-05-29 | Aicuris Gmbh & Co. Kg | Carboxamid-substituierte Heteroaryl-Pyrazole und ihre Verwendung |
| WO2013171687A1 (en) | 2012-05-16 | 2013-11-21 | Actelion Pharmaceuticals Ltd | 1-(p-tolyl)cyclopropyl substituted bridged spiro[2.4]heptane derivatives as alx receptor agonists |
| MA37618B1 (fr) | 2012-05-16 | 2017-08-31 | Actelion Pharmaceuticals Ltd | Dérivés pontés fluorés de spiro[2.4]heptane en tant qu'agonistes de récepteur alx |
| DE102012016908A1 (de) | 2012-08-17 | 2014-02-20 | Aicuris Gmbh & Co. Kg | Tris-(Hetero)Aryl-Pyrazole und ihre Verwendung |
| AR096686A1 (es) | 2013-06-25 | 2016-01-27 | Actelion Pharmaceuticals Ltd | Derivados de espiro[2.4]heptano puenteados sustituidos con difluoroetil-oxazol como agonistas del receptor de alx |
| ES2639798T3 (es) | 2013-07-18 | 2017-10-30 | Idorsia Pharmaceuticals Ltd | Derivados de espiro[2.4]heptano con puente sustituidos con piperazina como agonistas del receptor ALX |
| AR097279A1 (es) | 2013-08-09 | 2016-03-02 | Actelion Pharmaceuticals Ltd | Derivados de benzimidazolil-metil urea como agonistas del receptor de alx |
| NZ752095A (en) | 2013-11-28 | 2022-07-01 | Kyorin Seiyaku Kk | Urea derivative or pharmacologically acceptable salt thereof |
| US10858314B2 (en) | 2015-05-27 | 2020-12-08 | Kyorin Pharmaceutical Co., Ltd. | Urea derivative or pharmacologically acceptable salt thereof |
| US10525058B2 (en) | 2015-05-27 | 2020-01-07 | Kyorin Pharmaceutical Co., Ltd | Urea derivative or pharmacologically acceptable salt thereof |
| SG11202008504SA (en) | 2018-03-05 | 2020-10-29 | Bristol Myers Squibb Co | Phenylpyrrolidinone formyl peptide 2 receptor agonists |
| EP3774782A2 (en) * | 2018-04-06 | 2021-02-17 | Black Belt TX Ltd | Atf6 inhibitors and uses thereof |
| WO2023118434A1 (en) * | 2021-12-22 | 2023-06-29 | Globachem Nv | Pesticidally active amide compounds |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8531019D0 (en) * | 1985-12-17 | 1986-01-29 | Beecham Group Plc | Compounds |
| JPS62234018A (ja) | 1986-04-02 | 1987-10-14 | Rooto Seiyaku Kk | 糖尿病併発症治療剤 |
| HUP0202248A3 (en) * | 1999-03-12 | 2006-06-28 | Boehringer Ingelheim Pharma | Compounds useful as anti-inflammatory agents |
| US20040043904A1 (en) * | 2000-09-22 | 2004-03-04 | Hiroshi Yamaguchi | N-(4-pyrazolyl) amide derivatives, chemicals for agricultural and horticultural use, and usage of the same |
| EP1368345B1 (en) * | 2001-03-02 | 2006-03-22 | F. Hoffmann-La Roche AG | Alkoxycarbonylamino heteroaryl carboxylic acid derivatives as ip antagonists |
| EP1492552A2 (en) | 2002-04-03 | 2005-01-05 | Bayer Aktiengesellschaft | Diagnostics and therapeutics for diseases associated with n-formyl peptide receptor like 1 (fprl1) |
| US7135575B2 (en) * | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
| EP1692502A2 (en) | 2003-11-07 | 2006-08-23 | Acadia Pharmaceuticals Inc. | Use of the lipoxin receptor, fprl1, as a tool for identifying compounds effective in the treatment of pain and inflammation |
| GB0508472D0 (en) * | 2005-04-26 | 2005-06-01 | Glaxo Group Ltd | Compounds |
| US8026260B2 (en) | 2005-11-03 | 2011-09-27 | Merck Sharp & Dohme Corp. | Histone deacetylase inhibitors with aryl-pyrazolyl-motifs |
| GB0606876D0 (en) * | 2006-04-05 | 2006-05-17 | Glaxo Group Ltd | Compounds |
| ES2545121T3 (es) | 2007-08-21 | 2015-09-08 | Senomyx, Inc. | Compuestos que inhiben (bloquean) el sabor amargo en composiciones, y uso de los mismos |
| DK2225231T3 (da) | 2007-12-18 | 2011-10-17 | Actelion Pharmaceuticals Ltd | Aminotriazolderivater som alx-agonister |
| KR101724765B1 (ko) | 2009-05-18 | 2017-04-07 | 액테리온 파마슈티칼 리미티드 | Ａｌｘ 수용체 및/또는 ｆｐｒｌ2 아고니스트로서의 브릿지 스피로［2.4］헵탄 유도체 |
| JP5095035B2 (ja) | 2009-06-09 | 2012-12-12 | アクテリオン ファーマシューティカルズ リミテッド | フッ素化アミノトリアゾール誘導体 |
| US8674111B2 (en) | 2009-06-12 | 2014-03-18 | Actelion Pharmaceuticals Ltd. | Oxazole and thiazole derivatives as ALX receptor agonists |
-
2008
- 2008-12-11 AR ARP080105380A patent/AR069650A1/es unknown
- 2008-12-12 CA CA2706836A patent/CA2706836C/en not_active Expired - Fee Related
- 2008-12-12 EP EP08862120.6A patent/EP2242743B1/en not_active Not-in-force
- 2008-12-12 ES ES08862120T patent/ES2432059T3/es active Active
- 2008-12-12 US US12/808,137 patent/US8288419B2/en not_active Expired - Fee Related
- 2008-12-12 NZ NZ586776A patent/NZ586776A/en not_active IP Right Cessation
- 2008-12-12 MX MX2010005827A patent/MX2010005827A/es active IP Right Grant
- 2008-12-12 DK DK08862120.6T patent/DK2242743T3/da active
- 2008-12-12 CN CN2008801219752A patent/CN101903353B/zh not_active Expired - Fee Related
- 2008-12-12 PL PL08862120T patent/PL2242743T3/pl unknown
- 2008-12-12 PT PT88621206T patent/PT2242743E/pt unknown
- 2008-12-12 KR KR1020107015524A patent/KR101622413B1/ko not_active Expired - Fee Related
- 2008-12-12 JP JP2010537589A patent/JP5435744B2/ja not_active Expired - Fee Related
- 2008-12-12 RU RU2010128240/04A patent/RU2489426C2/ru not_active IP Right Cessation
- 2008-12-12 BR BRPI0821004A patent/BRPI0821004A8/pt not_active IP Right Cessation
- 2008-12-12 TW TW097148594A patent/TWI430795B/zh not_active IP Right Cessation
- 2008-12-12 SI SI200831072T patent/SI2242743T1/sl unknown
- 2008-12-12 MY MYPI2010002723A patent/MY153921A/en unknown
- 2008-12-12 WO PCT/IB2008/055251 patent/WO2009077954A1/en not_active Ceased
- 2008-12-12 HR HRP20131105AT patent/HRP20131105T1/hr unknown
-
2010
- 2010-06-10 IL IL206296A patent/IL206296A/en not_active IP Right Cessation
- 2010-06-29 MA MA32967A patent/MA31988B1/fr unknown
- 2010-07-13 ZA ZA2010/04939A patent/ZA201004939B/en unknown
-
2013
- 2013-11-20 CY CY20131101025T patent/CY1114793T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: IDORSIA PHARMACEUTICALS LTD (CH) |
|
| B25L | Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled |
Owner name: ACTELION PHARMACEUTICALS LTD (CH) |
|
| B25C | Requirement related to requested transfer of rights |
Owner name: ACTELION PHARMACEUTICALS LTD (CH) |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: IDORSIA PHARMACEUTICALS LTD (CH) |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 11A ANUIDADE. |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
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