CL2011000450A1 - Proceso para preparar una composicion farmaceutica que comprende a) mezclar un agonista del receptor s1p, seleccionado de 2-amino-2-[2-(4-octilfenil)etil]propano-1,3-diol y una sal del mismo, con un alcohol de azucar; b) moler y/o granular la mezcla; y c) mezclar la mezcla con un lubricante (divisional solicitud 745-2004). - Google Patents

Proceso para preparar una composicion farmaceutica que comprende a) mezclar un agonista del receptor s1p, seleccionado de 2-amino-2-[2-(4-octilfenil)etil]propano-1,3-diol y una sal del mismo, con un alcohol de azucar; b) moler y/o granular la mezcla; y c) mezclar la mezcla con un lubricante (divisional solicitud 745-2004).

Info

Publication number
CL2011000450A1
CL2011000450A1 CL2011000450A CL2011000450A CL2011000450A1 CL 2011000450 A1 CL2011000450 A1 CL 2011000450A1 CL 2011000450 A CL2011000450 A CL 2011000450A CL 2011000450 A CL2011000450 A CL 2011000450A CL 2011000450 A1 CL2011000450 A1 CL 2011000450A1
Authority
CL
Chile
Prior art keywords
mixture
octylphenyl
granulate
grind
diol
Prior art date
Application number
CL2011000450A
Other languages
English (en)
Inventor
Colleen Ruegger
Alan Edward Royce
Madhusudhan Pudipeddi
Tomoyuki Oomura
Masaki Sasaki
Tokuhiro Tamura
Original Assignee
Novartis Ag
Mitsubishi Tanabe Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32326722&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2011000450(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag, Mitsubishi Tanabe Pharma Corp filed Critical Novartis Ag
Publication of CL2011000450A1 publication Critical patent/CL2011000450A1/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
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    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
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    • A61K9/2022—Organic macromolecular compounds
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    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Proceso para preparar una composición farmacéutica que comprende A) Mezclar un agonista del receptor s1p, seleccionado de 2-amino-2-[2- (4-octilfenil) etil] propano-1,3-diol y una sal del mismo, con un alcohol de azúcar; B) Moler y/o granularla mezcla; y C) Mezclar la mezcla con un lubricante (Divisional Solicitud 745-2004).
CL2011000450A 2003-04-08 2011-03-01 Proceso para preparar una composicion farmaceutica que comprende a) mezclar un agonista del receptor s1p, seleccionado de 2-amino-2-[2-(4-octilfenil)etil]propano-1,3-diol y una sal del mismo, con un alcohol de azucar; b) moler y/o granular la mezcla; y c) mezclar la mezcla con un lubricante (divisional solicitud 745-2004). CL2011000450A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46121503P 2003-04-08 2003-04-08

Publications (1)

Publication Number Publication Date
CL2011000450A1 true CL2011000450A1 (es) 2011-11-25

Family

ID=32326722

Family Applications (2)

Application Number Title Priority Date Filing Date
CL200400745A CL2004000745A1 (es) 2003-04-08 2004-04-07 Composicion farmaceutica solida para administracion oral que comprende un agonista del receptor s1p y un alcohol de azucar.
CL2011000450A CL2011000450A1 (es) 2003-04-08 2011-03-01 Proceso para preparar una composicion farmaceutica que comprende a) mezclar un agonista del receptor s1p, seleccionado de 2-amino-2-[2-(4-octilfenil)etil]propano-1,3-diol y una sal del mismo, con un alcohol de azucar; b) moler y/o granular la mezcla; y c) mezclar la mezcla con un lubricante (divisional solicitud 745-2004).

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CL200400745A CL2004000745A1 (es) 2003-04-08 2004-04-07 Composicion farmaceutica solida para administracion oral que comprende un agonista del receptor s1p y un alcohol de azucar.

Country Status (41)

Country Link
US (11) US20060275357A1 (es)
EP (5) EP1613288B1 (es)
JP (3) JP5495467B2 (es)
KR (3) KR20110005320A (es)
CN (2) CN1767819B (es)
AR (3) AR043987A1 (es)
AT (3) ATE414508T1 (es)
AU (1) AU2004228929B2 (es)
BE (2) BE1015972A5 (es)
BR (1) BRPI0409250B8 (es)
CA (2) CA2707750A1 (es)
CL (2) CL2004000745A1 (es)
CY (3) CY1110260T1 (es)
DE (4) DE202004021680U1 (es)
DK (2) DK2316431T3 (es)
EC (1) ECSP056090A (es)
ES (3) ES2556947T3 (es)
FR (2) FR2854073B1 (es)
GB (1) GB2400318B (es)
GR (1) GR1005052B (es)
HR (3) HRP20100601B1 (es)
HU (2) HUE028247T2 (es)
IL (3) IL170888A (es)
IS (2) IS2682B (es)
IT (1) ITMI20040682A1 (es)
LU (1) LU91867I2 (es)
MA (1) MA27729A1 (es)
MX (1) MXPA05010860A (es)
MY (1) MY141249A (es)
NO (4) NO329332B1 (es)
NZ (3) NZ586280A (es)
PE (5) PE20131352A1 (es)
PL (2) PL2316431T3 (es)
PT (1) PT1613288E (es)
RU (5) RU2358716C2 (es)
SG (1) SG175449A1 (es)
SI (2) SI2316431T1 (es)
TN (1) TNSN05256A1 (es)
TW (1) TWI332847B (es)
WO (1) WO2004089341A1 (es)
ZA (1) ZA200507394B (es)

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