CL2011000480A1 - Compuestos derivados de amino-1,2,4-triazolo[1,5-a]piridina sustituidos, inhibidores de quinasa; composicion farmaceutica; y su uso para el tratamiento o prevencion de condiciones inflamatorias, inmunologicas, autoinmunes, alergicas, reumaticas, tromboticas, cancer, infecciones, padecimientos neurodegenerativos, entre otras. - Google Patents
Compuestos derivados de amino-1,2,4-triazolo[1,5-a]piridina sustituidos, inhibidores de quinasa; composicion farmaceutica; y su uso para el tratamiento o prevencion de condiciones inflamatorias, inmunologicas, autoinmunes, alergicas, reumaticas, tromboticas, cancer, infecciones, padecimientos neurodegenerativos, entre otras.Info
- Publication number
- CL2011000480A1 CL2011000480A1 CL2011000480A CL2011000480A CL2011000480A1 CL 2011000480 A1 CL2011000480 A1 CL 2011000480A1 CL 2011000480 A CL2011000480 A CL 2011000480A CL 2011000480 A CL2011000480 A CL 2011000480A CL 2011000480 A1 CL2011000480 A1 CL 2011000480A1
- Authority
- CL
- Chile
- Prior art keywords
- thrombotic
- rheumatic
- immunological
- allergic
- infections
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 208000025747 Rheumatic disease Diseases 0.000 title abstract 2
- 230000000172 allergic effect Effects 0.000 title abstract 2
- 208000010668 atopic eczema Diseases 0.000 title abstract 2
- 230000001363 autoimmune Effects 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000001900 immune effect Effects 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 230000002757 inflammatory effect Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Chemical class 0.000 title abstract 2
- 230000000552 rheumatic effect Effects 0.000 title abstract 2
- 230000001732 thrombotic effect Effects 0.000 title abstract 2
- PHTMVIAGTMTVSK-UHFFFAOYSA-N [1,2,4]triazolo[1,5-a]pyridin-2-amine Chemical class C1=CC=CN2N=C(N)N=C21 PHTMVIAGTMTVSK-UHFFFAOYSA-N 0.000 title 1
- 229940043355 kinase inhibitor Drugs 0.000 title 1
- 230000004770 neurodegeneration Effects 0.000 title 1
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
- 239000003757 phosphotransferase inhibitor Chemical class 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- KLSJWNVTNUYHDU-UHFFFAOYSA-N Amitrole Chemical compound NC1=NC=NN1 KLSJWNVTNUYHDU-UHFFFAOYSA-N 0.000 abstract 1
- 230000000626 neurodegenerative effect Effects 0.000 abstract 1
Classifications
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
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Abstract
COMPUESTOS DERIVADOS DE AMINO -1,2,4-TRIAZOL(1,5-A) PIRIDINA SUSTITUIDOS DE FORMULA;<br /> DONDE R1 Y R2 SON COMO SE DEFINE EN LA MEMORIA DESCRIPTIVA Y PLIEGO DE REIVINDICACIONES, COMPOSICION FARMACEUTICA Y SU USO PARA TRATAR O PREVENIR CONDICIONES INFLAMATORIAS, INMUNOLOGICAS, AUTOINMUNES, ALERGICAS, REUMATICAS, TROMBOTICAS, CANCER, INFECCIONES, PADECIMIENTOS NEURODEGENERATIVOS, ENTRE OTRAS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9521708P | 2008-09-08 | 2008-09-08 | |
| US23047909P | 2009-07-31 | 2009-07-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2011000480A1 true CL2011000480A1 (es) | 2011-09-16 |
Family
ID=41228355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2011000480A CL2011000480A1 (es) | 2008-09-08 | 2011-03-07 | Compuestos derivados de amino-1,2,4-triazolo[1,5-a]piridina sustituidos, inhibidores de quinasa; composicion farmaceutica; y su uso para el tratamiento o prevencion de condiciones inflamatorias, inmunologicas, autoinmunes, alergicas, reumaticas, tromboticas, cancer, infecciones, padecimientos neurodegenerativos, entre otras. |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US8299056B2 (es) |
| EP (1) | EP2344494B1 (es) |
| JP (1) | JP5689060B2 (es) |
| KR (1) | KR20110053266A (es) |
| CN (2) | CN102203093B (es) |
| AU (1) | AU2009288618B2 (es) |
| BR (1) | BRPI0918854A2 (es) |
| CA (1) | CA2735806A1 (es) |
| CL (1) | CL2011000480A1 (es) |
| CO (1) | CO6531502A2 (es) |
| CR (1) | CR20110132A (es) |
| EC (1) | ECSP11010945A (es) |
| ES (1) | ES2581565T3 (es) |
| IL (1) | IL211549A (es) |
| MX (1) | MX2011002536A (es) |
| NI (1) | NI201100048A (es) |
| NZ (1) | NZ591551A (es) |
| PE (1) | PE20110387A1 (es) |
| RU (1) | RU2552642C2 (es) |
| TW (1) | TWI453207B (es) |
| WO (1) | WO2010027500A1 (es) |
| ZA (1) | ZA201101586B (es) |
Families Citing this family (151)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60100852A (ja) * | 1984-09-28 | 1985-06-04 | Hitachi Ltd | 情報伝送方法 |
| AU2005274927B2 (en) | 2004-07-15 | 2011-11-03 | Albany Molecular Research, Inc. | Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
| NZ587039A (en) | 2008-02-13 | 2013-01-25 | Gilead Connecticut Inc | 6-aryl-imidazo[1, 2-a]pyrazine derivatives, method of making, and method of use thereof |
| AU2009216851B2 (en) | 2008-02-22 | 2013-11-07 | F. Hoffmann-La Roche Ag | Modulators for amyloid beta |
| US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
| US20100035875A1 (en) * | 2008-06-20 | 2010-02-11 | Bing-Yan Zhu | Triazolopyridine jak inhibitor compounds and methods |
| GB0817207D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | therapeutic apsac compounds and their use |
| WO2010040661A1 (en) | 2008-10-09 | 2010-04-15 | F. Hoffmann-La Roche Ag | Modulators for amyloid beta |
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| CN113583110B (zh) * | 2021-08-19 | 2023-07-21 | 华南农业大学 | 一种苯并三唑半抗原、人工抗原和抗体及其制备方法与应用 |
| CN113801152B (zh) * | 2021-08-30 | 2023-08-11 | 上海日异生物科技有限公司 | 3-羧基-5-羟基苯硼酸的合成方法 |
| CN115819425A (zh) * | 2022-12-22 | 2023-03-21 | 五邑大学 | 一种三唑并六元氮杂环-2-胺类化合物及其制备方法和应用 |
| CN116621764B (zh) * | 2023-03-06 | 2026-03-31 | 南京合巨药业有限公司 | 一种3,3-二甲基-6-硝基-1,3-二氢吲哚-2-酮的制备方法 |
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| KR20260054550A (ko) * | 2024-10-15 | 2026-04-22 | 한국화학연구원 | JAK1를 선택적으로 저해하는 신규한 테트라하이드로이소퀴놀린 또는 이소인돌린 치환 [1,2,4]트리아졸로[1,5-a]피리딘 유도체 및 이의 용도 |
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-
2009
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- 2009-09-08 ES ES09789271.5T patent/ES2581565T3/es active Active
- 2009-09-08 CN CN200980144169.1A patent/CN102203093B/zh not_active Expired - Fee Related
- 2009-09-08 BR BRPI0918854-1A patent/BRPI0918854A2/pt not_active IP Right Cessation
- 2009-09-08 KR KR1020117007996A patent/KR20110053266A/ko not_active Ceased
- 2009-09-08 NZ NZ591551A patent/NZ591551A/en not_active IP Right Cessation
- 2009-09-08 US US12/555,018 patent/US8299056B2/en active Active
- 2009-09-08 AU AU2009288618A patent/AU2009288618B2/en not_active Ceased
- 2009-09-08 PE PE2011000599A patent/PE20110387A1/es not_active Application Discontinuation
- 2009-09-08 CA CA2735806A patent/CA2735806A1/en not_active Abandoned
- 2009-09-08 RU RU2011113540/04A patent/RU2552642C2/ru not_active IP Right Cessation
- 2009-09-08 EP EP09789271.5A patent/EP2344494B1/en active Active
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- 2009-09-08 WO PCT/US2009/005020 patent/WO2010027500A1/en not_active Ceased
- 2009-09-08 JP JP2011526054A patent/JP5689060B2/ja not_active Expired - Fee Related
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2011
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- 2011-03-03 IL IL211549A patent/IL211549A/en not_active IP Right Cessation
- 2011-03-07 CL CL2011000480A patent/CL2011000480A1/es unknown
- 2011-03-07 NI NI201100048A patent/NI201100048A/es unknown
- 2011-03-11 CR CR20110132A patent/CR20110132A/es unknown
- 2011-04-01 EC EC2011010945A patent/ECSP11010945A/es unknown
- 2011-04-05 CO CO11041595A patent/CO6531502A2/es not_active Application Discontinuation
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2012
- 2012-09-11 US US13/609,412 patent/US20130005707A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0918854A2 (pt) | 2019-02-26 |
| ZA201101586B (en) | 2012-05-30 |
| RU2011113540A (ru) | 2012-10-20 |
| AU2009288618B2 (en) | 2014-10-02 |
| US8299056B2 (en) | 2012-10-30 |
| PE20110387A1 (es) | 2011-06-22 |
| CR20110132A (es) | 2011-06-20 |
| JP2012502029A (ja) | 2012-01-26 |
| CN104910148B (zh) | 2017-06-27 |
| KR20110053266A (ko) | 2011-05-19 |
| US20100093698A1 (en) | 2010-04-15 |
| US20130005707A1 (en) | 2013-01-03 |
| AU2009288618A1 (en) | 2010-03-11 |
| CA2735806A1 (en) | 2010-03-11 |
| TWI453207B (zh) | 2014-09-21 |
| CO6531502A2 (es) | 2012-09-28 |
| IL211549A (en) | 2017-04-30 |
| ECSP11010945A (es) | 2011-05-31 |
| RU2552642C2 (ru) | 2015-06-10 |
| ES2581565T3 (es) | 2016-09-06 |
| IL211549A0 (en) | 2011-05-31 |
| NZ591551A (en) | 2011-10-28 |
| CN102203093A (zh) | 2011-09-28 |
| CN104910148A (zh) | 2015-09-16 |
| WO2010027500A1 (en) | 2010-03-11 |
| MX2011002536A (es) | 2011-04-04 |
| JP5689060B2 (ja) | 2015-03-25 |
| NI201100048A (es) | 2011-11-17 |
| TW201024293A (en) | 2010-07-01 |
| CN102203093B (zh) | 2015-05-13 |
| EP2344494A1 (en) | 2011-07-20 |
| EP2344494B1 (en) | 2016-04-20 |
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