CL2015003111A1 - Composición sólida hemostática que comprende un vehículo de colágeno con al menos 2 características entre un módulo de elasticidad de 10 a 50 n/cm2, densidad de 1 a 10 mg/cm2 y un diámetro de cámara de 0,75 a 4 mn. (divisional solicitud 163-2002) - Google Patents

Composición sólida hemostática que comprende un vehículo de colágeno con al menos 2 características entre un módulo de elasticidad de 10 a 50 n/cm2, densidad de 1 a 10 mg/cm2 y un diámetro de cámara de 0,75 a 4 mn. (divisional solicitud 163-2002)

Info

Publication number
CL2015003111A1
CL2015003111A1 CL2015003111A CL2015003111A CL2015003111A1 CL 2015003111 A1 CL2015003111 A1 CL 2015003111A1 CL 2015003111 A CL2015003111 A CL 2015003111A CL 2015003111 A CL2015003111 A CL 2015003111A CL 2015003111 A1 CL2015003111 A1 CL 2015003111A1
Authority
CL
Chile
Prior art keywords
vehicle
chamber diameter
covered
solid composition
elasticity
Prior art date
Application number
CL2015003111A
Other languages
English (en)
Inventor
Dagmar Stimmeder
Original Assignee
Takeda Nycomed As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Nycomed As filed Critical Takeda Nycomed As
Publication of CL2015003111A1 publication Critical patent/CL2015003111A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/36—Surgical swabs, e.g. for absorbency or packing body cavities during surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/425—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/044—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/046—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/00463—Plasters use haemostatic
    • A61F2013/00472—Plasters use haemostatic with chemical means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Medicinal Preparation (AREA)

Abstract

UNA COMPOSICION SOLIDA PARA HEMOSTASIS, SELLAR TEJIDOS Y PEGAR TEJIDOS, QUE CONSISTE ESENCIALMENTE EN UN VEHICULO DE COLAGENO FLEXIBLE, EL QUE AL MENOS TIENE DOS DE LAS SIGUIENTES PROPIEDADES FISICAS: MODULO DE ELASTICIDAD EN EL INTERVALO DE 10-50 N/cm2 , DENSIDAD DE 1-10 mg/cm3 , DIAMETRO DE CAMARA MAYOR QUE 0,75 mm Y MENOR QUE 4 mm Y/O QUE TIENE UN DIAMETRO DE CAMARA MEDIO INFERIOR A 3 mm, Y QUE ADEMAS COMPRENDE UNA MEZCLA DE: FIBRINOGENO SOLIDO Y TROMBINA SOLIDA Y NO COMPRENDE NINGUN AGENTE ANTIFIBRINOLITICO TAL COMO APROTININA, ACIDO E-AMINOCAPROICO O A2-ANTIPLASMINA, SIENDO DICHO MATERIAL SUSTANCIALMENTE ESTANCO AL AIRE Y ESTANCO A LOS LIQUIDOS, Y CON UN FACTOR DE ELASTICIDAD DE AL MENOS 1,25, DETERMINADO POR UN ENSAYO QUE COMPRENDE FIJAR EL VEHICULO REVESTIDO EN UNA LAMINA DE LATEX, EXPANSION DEL LATEX POR PRESION TRES VECES, Y LA TERCERA VEZ MEDICION DE LA SUPERFICIE DEL VEHICULO REVESTIDO EN EL PUNTO MAS ALTO DE LA EXPANSION DE LA LAMINA DE LATEX, Y COMPARACION DE LA SUPERFICIE EXPANDIDA DEL VEHICULO REVESTIDO CON LA SUPERFICIE INICIAL DE LA SUPERFICIE REVESTIDA.
CL2015003111A 2001-01-25 2015-10-21 Composición sólida hemostática que comprende un vehículo de colágeno con al menos 2 características entre un módulo de elasticidad de 10 a 50 n/cm2, densidad de 1 a 10 mg/cm2 y un diámetro de cámara de 0,75 a 4 mn. (divisional solicitud 163-2002) CL2015003111A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200100135 2001-01-25
DKPA200100235 2001-02-13

Publications (1)

Publication Number Publication Date
CL2015003111A1 true CL2015003111A1 (es) 2016-07-08

Family

ID=26068956

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015003111A CL2015003111A1 (es) 2001-01-25 2015-10-21 Composición sólida hemostática que comprende un vehículo de colágeno con al menos 2 características entre un módulo de elasticidad de 10 a 50 n/cm2, densidad de 1 a 10 mg/cm2 y un diámetro de cámara de 0,75 a 4 mn. (divisional solicitud 163-2002)

Country Status (36)

Country Link
EP (4) EP1368419B1 (es)
JP (4) JP4104462B2 (es)
KR (2) KR100830294B1 (es)
CN (3) CN1290907C (es)
AR (3) AR032517A1 (es)
AT (2) ATE310044T1 (es)
AU (3) AU2002249528B2 (es)
BG (3) BG66420B1 (es)
BR (3) BRPI0206705B8 (es)
CA (3) CA2435425C (es)
CL (1) CL2015003111A1 (es)
CR (1) CR7034A (es)
CZ (3) CZ305120B6 (es)
DE (2) DE60203364T2 (es)
DK (2) DK1343542T3 (es)
EA (4) EA006540B1 (es)
EE (3) EE05587B1 (es)
EG (2) EG26417A (es)
ES (2) ES2238569T3 (es)
HR (1) HRP20030648B1 (es)
HU (3) HU228810B1 (es)
IL (6) IL157096A0 (es)
IS (1) IS6885A (es)
ME (1) ME00587A (es)
MX (3) MXPA03006687A (es)
NO (3) NO332462B1 (es)
NZ (3) NZ527167A (es)
PL (3) PL206194B1 (es)
PT (1) PT1343542E (es)
RS (1) RS50866B (es)
SI (2) SI1343542T1 (es)
SK (3) SK288120B6 (es)
TW (2) TWI237573B (es)
UA (1) UA73028C2 (es)
UY (1) UY27136A1 (es)
WO (3) WO2002058750A2 (es)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020131933A1 (en) * 1996-01-16 2002-09-19 Yves Delmotte Biopolymer membrane and methods for its preparation
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
US7279177B2 (en) 2002-06-28 2007-10-09 Ethicon, Inc. Hemostatic wound dressings and methods of making same
US7252837B2 (en) 2002-06-28 2007-08-07 Ethicon, Inc. Hemostatic wound dressing and method of making same
CA2504706A1 (en) * 2002-11-04 2004-05-21 Nycomed Danmark Aps Coating of a particulate material with an organic solvent-based coating composition
US20060051340A1 (en) * 2003-01-20 2006-03-09 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Hemostatic materials
MXPA05010692A (es) 2003-04-04 2006-04-18 Tissuemed Ltd Formulaciones que se adhieren a tejido.
US8834864B2 (en) * 2003-06-05 2014-09-16 Baxter International Inc. Methods for repairing and regenerating human dura mater
US20040265371A1 (en) 2003-06-25 2004-12-30 Looney Dwayne Lee Hemostatic devices and methods of making same
US7927626B2 (en) 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
US7186684B2 (en) * 2003-08-07 2007-03-06 Ethicon, Inc. Hemostatic device containing a protein precipitate
BRPI0514106A (pt) 2004-08-03 2008-05-27 Tissuemed Ltd materiais adesivos a tecidos
ES2537088T3 (es) 2004-10-20 2015-06-02 Ethicon, Inc. Tejido multicapa absorbible reforzado para su uso en dispositivos médicos y método de fabricación
US9358318B2 (en) 2004-10-20 2016-06-07 Ethicon, Inc. Method of making a reinforced absorbable multilayered hemostatic wound dressing
ES2530989T3 (es) 2004-10-20 2015-03-09 Ethicon Inc Hemostático absorbible
KR20060040329A (ko) * 2004-11-05 2006-05-10 나건 내시경을 통하여 도포 가능한 체내 지혈제 및 그 도포 방법
KR20100102750A (ko) 2005-04-25 2010-09-24 메사추세츠 인스티튜트 오브 테크놀로지 지혈 및 다른 생리학적 활성을 촉진하기 위한 조성물 및 방법
JP4864348B2 (ja) * 2005-05-27 2012-02-01 川澄化学工業株式会社 神経再生チューブ
CA2640629A1 (en) 2006-02-03 2007-08-09 Tissuemed Limited Tissue-adhesive materials
CA2640560C (en) * 2006-02-14 2017-07-11 Commonwealth Scientific And Industrial Research Organisation Joining and/or sealing tissues through photo-activated cross-linking of matrix proteins
HUE037994T2 (hu) 2006-04-25 2018-09-28 Massachusetts Inst Technology Készítmények és eljárások szennyezõ anyagok, testfolyadékok vagy más anyagok mozgásának befolyásolására és/vagy más fiziológiai állapotok befolyásolására
KR20090017654A (ko) 2006-05-31 2009-02-18 백스터 인터내셔널 인코포레이티드 척수 수술에서 세포 내성장을 통제하고 조직 재생을 조절하는 방법
TWI436793B (zh) 2006-08-02 2014-05-11 巴克斯特國際公司 快速作用之乾密封膠及其使用和製造方法
US8445009B2 (en) * 2006-08-04 2013-05-21 Stb, Ltd Processes for the production of solid dressings for treating wounded tissue
GB0623607D0 (en) 2006-11-27 2007-01-03 Haemostatix Ltd Tissue adhesive
KR101215136B1 (ko) * 2007-02-05 2012-12-24 더 재팬 스틸 워크스 엘티디 수소흡장합금과 수지를 포함하는 조성물
CN101053679B (zh) * 2007-04-17 2010-05-26 浙江大学 一种纤维蛋白凝胶填充的聚合物多孔支架的制备方法
DE102007037056A1 (de) 2007-07-24 2009-01-29 Aesculap Ag Hämostyptikum
DE102007037053A1 (de) 2007-07-24 2009-01-29 Aesculap Ag Hämostyptikum für die minimal-invasive Operation
DE102007045066A1 (de) 2007-09-20 2009-04-02 Mike Ehrlich Material zur Blutstillung enthaltend synthetische Peptide oder Polysaccharide
DE102007000574A1 (de) 2007-10-25 2009-04-30 FILK Forschungsinstitut für Leder- und Kunstbahnen gGmbH Biologisch resorbierbares Schwammmaterial und Verfahren zu dessen Herstellung
US8790698B2 (en) 2007-10-30 2014-07-29 Baxter International Inc. Use of a regenerative biofunctional collagen biomatrix for treating visceral or parietal defects
CN101214391B (zh) * 2007-12-27 2010-05-19 广州倍绣生物技术有限公司 一种高效生物胶封闭剂及其应用
CN102014973A (zh) 2008-02-29 2011-04-13 弗罗桑医疗设备公司 用于促进止血和/或伤口愈合的装置
WO2010002435A2 (en) * 2008-07-03 2010-01-07 Kulinets Irina B Hemostatic pouch and method to stabilize hemostatic components
CN105435211A (zh) 2008-10-06 2016-03-30 三维肽胶株式会社 组织闭塞剂
US9039783B2 (en) 2009-05-18 2015-05-26 Baxter International, Inc. Method for the improvement of mesh implant biocompatibility
US9162006B2 (en) 2009-06-16 2015-10-20 Baxter International Inc. Hemostatic sponge
EP2477617B1 (en) 2009-09-18 2018-01-31 Bioinspire Technologies Inc. Free-standing biodegradable patch
US9271925B2 (en) 2013-03-11 2016-03-01 Bioinspire Technologies, Inc. Multi-layer biodegradable device having adjustable drug release profile
WO2011072482A1 (en) 2009-12-14 2011-06-23 The University Of Hong Kong Nano cancer barrier device(ncbd) to immobilize and inhibit the division of metastic cancer stem cells
WO2011079336A1 (en) 2009-12-16 2011-07-07 Baxter International Inc. Hemostatic sponge
ES2513516T3 (es) 2010-01-28 2014-10-27 Omrix Biopharmaceuticals Ltd. Método para un sellado con fibrina mejorado
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
ES2682302T3 (es) 2010-06-01 2018-09-19 Baxter International Inc Proceso para la producción de composiciones hemostáticas secas y estables
MX344402B (es) 2010-06-01 2016-12-14 Baxter Int Inc * Proceso para elaborar composiciones hemostaticas secas y estables.
AU2011260260B2 (en) 2010-06-01 2015-09-03 Baxter Healthcare S.A. Process for making dry and stable hemostatic compositions
JP5889188B2 (ja) * 2010-07-20 2016-03-22 一般財団法人化学及血清療法研究所 組織接着用シート製剤
HUE032689T4 (en) * 2011-05-24 2017-11-28 Takeda As Collagen carrier that has grown up
RU2013155713A (ru) * 2011-07-06 2015-08-20 Профибрикс Бв Составы для лечения ран
CN102357259A (zh) 2011-07-28 2012-02-22 王珊珊 一种生物蛋白海绵及其制备方法
US20130041406A1 (en) * 2011-08-10 2013-02-14 Brian W. Bear Surgical staple with localized adjunct coating
EP2556842A1 (en) 2011-08-11 2013-02-13 Bioftalmik, S.L. Composition in the form of film comprising fibrinogen and a fibrinogen activator and the applications thereof
HK1201212A1 (en) 2011-10-11 2015-08-28 Baxter International Inc Hemostatic compositions
ES2938568T3 (es) 2011-10-11 2023-04-12 Baxter Int Composiciones hemostaticas
SG11201401878SA (en) 2011-10-27 2014-09-26 Baxter Int Hemostatic compositions
WO2013131520A2 (en) 2012-03-06 2013-09-12 Ferrosan Medical Devices A/S Pressurized container containing haemostatic paste
AR091031A1 (es) * 2012-05-14 2014-12-30 Teijin Ltd Producto en planchas y material hemostatico
CN104470475B (zh) 2012-05-24 2017-04-19 武田有限公司 用于提供卷绕的胶原蛋白载体的设备和工艺
US10485715B2 (en) 2012-05-24 2019-11-26 Takeda As Packaging for form-stable coiled collagen carrier
RU2636240C2 (ru) 2012-06-12 2017-11-21 Ферросан Медикал Дивайсиз А/С Сухая гемостатическая композиция
EP2869903B1 (en) 2012-07-06 2018-11-28 3-D Matrix Ltd. Fill-finish process for peptide solutions
DE102013004420A1 (de) 2012-08-20 2014-02-20 Alexander Kopp Stützkörper und Verfahren zu seiner Herstellung
EP2928511B1 (en) * 2012-12-07 2020-04-22 Baxter International Inc. Hemostatic foam
KR101401944B1 (ko) * 2012-12-11 2014-05-30 세원셀론텍(주) 콜라겐과 피브린이 혼합된 조직 실란트 및 그 제조방법
EP3010419B1 (en) 2013-06-21 2020-05-20 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
US10765774B2 (en) 2013-07-09 2020-09-08 Ethicon, Inc. Hemostatic pad assembly kit and method
JP6489485B2 (ja) 2013-12-11 2019-03-27 フェロサン メディカル デバイシーズ エイ／エス 押し出し増強因子を含んでいる乾燥組成物
ES2712608T3 (es) 2014-03-10 2019-05-14 3 D Matrix Ltd Péptidos autoensamblantes para el tratamiento de las bullas pulmonares
DK3116896T3 (en) 2014-03-10 2019-03-18 3 D Matrix Ltd SELF-PREPARING PEPTIME COMPOSITIONS
ES3037364T3 (en) 2014-03-10 2025-10-01 3 D Matrix Ltd Sterilization and filtration of peptide compositions
CA2960309A1 (en) 2014-10-13 2016-04-21 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
RU2705905C2 (ru) 2014-12-24 2019-11-12 Ферросан Медикал Дивайсиз А/С Шприц для удерживания и смешивания первого и второго веществ
AU2016290433B2 (en) 2015-07-03 2018-05-24 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
WO2017120092A1 (en) 2016-01-06 2017-07-13 3-D Matrix, Ltd. Combination compositions
CN106267328B (zh) * 2016-09-20 2019-04-12 安徽思维特生物科技有限公司 一种聚己内酯-胎牛皮胶原纤维复合止血凝胶的制备方法
CN106730031A (zh) * 2016-12-30 2017-05-31 清华大学 一种用于脊髓损伤修复的仿生纤维蛋白水凝胶束及其制备方法
CN117085140A (zh) 2017-12-15 2023-11-21 立美基股份有限公司 表面活性剂肽纳米结构及在药物递送中的用途
ES2968412T3 (es) 2018-05-09 2024-05-09 Ferrosan Medical Devices As Método para preparar una composición hemostática
RU2679616C1 (ru) * 2018-07-02 2019-02-12 Государственное бюджетное учреждение здравоохранения города Москвы Научно-исследовательский институт скорой помощи имени Н.В. Склифосовского Департамента здравоохранения г. Москвы Способ приготовления тромбофибринового сгустка, обладающего ростстимулирующими свойствами
WO2020122007A1 (ja) * 2018-12-14 2020-06-18 株式会社ビーエムジー ２反応剤型のシート状組織接着補強材
MX2021011420A (es) 2019-03-20 2021-10-13 Astellas Pharma Inc Lamina hemostatica portadora de trombina.
US20210228765A1 (en) * 2020-01-28 2021-07-29 Becton, Dickinson And Company Self-activating catheter insertion site dressing
CN112225937B (zh) * 2020-10-14 2022-11-01 中山大学 一种温敏型大孔生物水凝胶及其制备方法和应用
CN113117158B (zh) * 2021-03-10 2022-07-26 复旦大学 表面变性蛋白生物功能化修饰的材料及其制备方法和应用
CN114246974B (zh) * 2021-12-24 2023-11-03 中国人民解放军军事科学院军事医学研究院 一种止血贴的制备方法
CN114177346B (zh) * 2021-12-24 2023-05-26 中国人民解放军军事科学院军事医学研究院 一种止血组合物及止血贴与其应用
WO2025023336A1 (ko) * 2023-07-21 2025-01-30 주식회사 덴하우스 지혈용 스펀지
PL248607B1 (pl) * 2023-12-18 2026-01-05 Politechnika Lodzka Sposób wytwarzania wielowarstwowej kompozytowej pianki

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1596789A (es) * 1968-11-27 1970-06-22
DE3105624A1 (de) * 1981-02-16 1982-09-02 Hormon-Chemie München GmbH, 8000 München Material zum abdichten und heilen von wunden
BR8102435A (pt) * 1981-04-15 1982-11-30 Campos Vidal Benedicto Colageno i microfibrilar e microcristalino para aplicacao em medicina e farmacia
DE3214337C2 (de) * 1982-04-19 1984-04-26 Serapharm - Michael Stroetmann, 4400 Münster Resorbierbares Flachmaterial zum Abdichten und Heilen von Wunden und Verfahren zu dessen Herstellung
US4626286A (en) * 1983-10-31 1986-12-02 Schmid Laboratories, Inc. Collagen gel and the process of making said gel
US5318524A (en) * 1990-01-03 1994-06-07 Cryolife, Inc. Fibrin sealant delivery kit
FR2668936B1 (fr) * 1990-11-09 1993-01-15 Eberlin Jean Luc Greffon a base de collagene et de colle de fibrine pour la reconstruction osteo-cartilagineuse et son procede de preparation.
CA2107473A1 (en) * 1991-04-08 1992-10-09 Keiji Fujioka Porous solid formulations containing proteinaceous physiologically active substances
US6177126B1 (en) * 1993-03-31 2001-01-23 Nycomed Arzneimittel Gmbh Process for the production of a material for sealing and healing wounds
AT410754B (de) * 1993-03-31 2003-07-25 Nycomed Austria Gmbh Vorrichtung zum gleichmässigen auftragen einer suspension auf einen kollagenträger
JPH0759812A (ja) * 1993-08-27 1995-03-07 Koken Co Ltd 創傷カバ−材及びその製造方法
EP0778884A1 (en) * 1994-09-02 1997-06-18 New York Blood Center, Inc. Production and secretion of recombinant fibrinogen by yeast
WO1997028832A1 (en) * 1996-02-06 1997-08-14 New Generation Medical Corporation Composition for sealing wounds
HUP9903586A3 (en) * 1996-04-04 2003-02-28 Baxter Ag Hemostatic sponge based on collagen
DE69906047T2 (de) * 1998-05-01 2003-10-16 Zymogenetics, Inc. Vollständig rekombinanter gewebekleber
JP4480270B2 (ja) * 1998-05-19 2010-06-16 ジ・アメリカン・ナショナル・レッド・クロス 止血サンドウィッチ包帯
MXPA01001510A (es) * 1998-08-10 2003-08-20 Fibrogen Inc Composiciones hemostaticas de colageno tipo i y tipo iii para usarse como sellador vascular y vendaje para heridas.
KR100804434B1 (ko) * 1998-12-23 2008-02-20 체에스엘 베링 게엠베하 피브린계 접착제 과립 및 이의 제조방법
DE19922078A1 (de) * 1999-05-15 2000-11-23 Weitzel Kage Doris Gewebekonstrukt für die Transplantationschirurgie

Also Published As

Publication number Publication date
MXPA03006689A (es) 2004-03-12
NO20033296D0 (no) 2003-07-22
NO20033296L (no) 2003-09-25
HK1058371A1 (en) 2004-05-14
EE200300341A (et) 2003-10-15
EA200300823A1 (ru) 2004-04-29
SK287874B6 (sk) 2012-02-03
CA2435425C (en) 2010-07-27
EG26417A (en) 2013-10-22
EP1343542B1 (en) 2005-03-23
EE05685B1 (et) 2013-12-16
BR0206709A (pt) 2004-02-17
AU2002307809B2 (en) 2007-10-04
KR100830294B1 (ko) 2008-05-16
IL157096A0 (en) 2004-02-08
HU227987B1 (hu) 2012-07-30
DE60203364D1 (de) 2005-04-28
PL206197B1 (pl) 2010-07-30
SI1368419T1 (sl) 2006-06-30
CZ20032197A3 (cs) 2003-11-12
WO2002070594A8 (en) 2004-03-11
KR20030086254A (ko) 2003-11-07
CA2435159A1 (en) 2002-09-12
CA2434964C (en) 2009-04-21
CZ304357B6 (cs) 2014-03-26
EA005697B1 (ru) 2005-04-28
IS6885A (is) 2003-07-24
EA200401463A1 (ru) 2005-08-25
ATE310044T1 (de) 2005-12-15
PL363274A1 (en) 2004-11-15
SK10362003A3 (sk) 2004-03-02
HUP0303893A3 (en) 2012-02-28
HK1058319A1 (en) 2004-05-14
DK1343542T3 (da) 2005-07-25
NO20033295D0 (no) 2003-07-22
RS50866B (sr) 2010-08-31
UA73028C2 (uk) 2005-05-16
AR032517A1 (es) 2003-11-12
IL157097A (en) 2009-12-24
ME00587B (me) 2011-12-20
MXPA03006687A (es) 2004-03-12
EP1343542A2 (en) 2003-09-17
WO2002058750A8 (en) 2004-03-11
EE05587B1 (et) 2012-10-15
CA2435159C (en) 2009-07-28
NZ527165A (en) 2005-02-25
DK1368419T3 (da) 2006-04-03
WO2002070594A3 (en) 2003-01-03
CR7034A (es) 2004-03-05
BR0206705B1 (pt) 2012-08-07
BG66439B1 (bg) 2014-08-29
WO2002058750A3 (en) 2002-10-31
NO20033295L (no) 2003-09-25
KR100847417B1 (ko) 2008-07-18
BG108123A (bg) 2004-09-30
JP2004520124A (ja) 2004-07-08
TWI255726B (en) 2006-06-01
HUP0303893A2 (hu) 2004-03-01
CA2435425A1 (en) 2002-08-01
BRPI0206709B8 (pt) 2021-06-22
EE200300349A (et) 2003-10-15
TWI237573B (en) 2005-08-11
CN1264578C (zh) 2006-07-19
EA200300822A1 (ru) 2004-02-26
ES2253523T3 (es) 2006-06-01
HUP0400768A3 (en) 2006-01-30
NZ527166A (en) 2005-03-24
CN1507358A (zh) 2004-06-23
HRP20030648A2 (en) 2005-06-30
SI1343542T1 (en) 2005-10-31
EE200300348A (et) 2003-10-15
PT1343542E (pt) 2005-08-31
HRP20030648B1 (en) 2011-10-31
IL157095A0 (en) 2004-02-08
ES2238569T3 (es) 2005-09-01
EP1368419A2 (en) 2003-12-10
NO20033297D0 (no) 2003-07-22
BRPI0206705B8 (pt) 2021-07-27
BRPI0206709B1 (pt) 2015-09-08
EA006540B1 (ru) 2006-02-24
BG108121A (bg) 2004-08-31
JP2004521115A (ja) 2004-07-15
EP1547626A2 (en) 2005-06-29
EP1368419B1 (en) 2005-11-16
BG66420B1 (bg) 2014-03-31
BR0206705A (pt) 2004-02-25
CN1487843A (zh) 2004-04-07
AR032800A1 (es) 2003-11-26
BRPI0206708B8 (pt) 2021-06-22
EP1547626A3 (en) 2009-07-29
CZ20032198A3 (cs) 2003-12-17
SK10352003A3 (sk) 2004-02-03
MXPA03006688A (es) 2004-03-12
NZ527167A (en) 2005-02-25
PL206194B1 (pl) 2010-07-30
HUP0400768A2 (hu) 2004-07-28
EP1359947A2 (en) 2003-11-12
BG108122A (bg) 2004-09-30
CZ305120B6 (cs) 2015-05-13
BG66343B1 (bg) 2013-07-31
IL157096A (en) 2007-08-19
EE05678B1 (et) 2013-10-15
PL363275A1 (en) 2004-11-15
HUP0303896A2 (hu) 2004-03-01
HUP0303896A3 (en) 2005-12-28
PL366932A1 (en) 2005-02-07
DE60203364T2 (de) 2005-09-01
WO2002058749A8 (en) 2004-03-11
CN1246047C (zh) 2006-03-22
EA200300821A1 (ru) 2004-04-29
JP2007190399A (ja) 2007-08-02
ME00587A (en) 2011-12-20
KR20030085522A (ko) 2003-11-05
BRPI0206708B1 (pt) 2015-07-14
EA006700B1 (ru) 2006-02-24
PL205181B1 (pl) 2010-03-31
NO332462B1 (no) 2012-09-24
WO2002058749A2 (en) 2002-08-01
NO20033297L (no) 2003-09-25
EG24589A (en) 2009-12-01
CZ20032199A3 (cs) 2003-12-17
IL157097A0 (en) 2004-02-08
SK288120B6 (sk) 2013-09-03
WO2002058750A2 (en) 2002-08-01
YU67003A (sh) 2006-05-25
AR032400A1 (es) 2003-11-05
IL157095A (en) 2009-06-15
JP2005502733A (ja) 2005-01-27
CA2434964A1 (en) 2002-08-01
CN1290907C (zh) 2006-12-20
JP4104462B2 (ja) 2008-06-18
EA006686B1 (ru) 2006-02-24
AU2002249528B2 (en) 2007-03-29
WO2002058749A3 (en) 2002-10-10
JP4535678B2 (ja) 2010-09-01
HU228810B1 (hu) 2013-05-28
DE60207389T2 (de) 2006-08-03
UY27136A1 (es) 2002-09-30
DE60207389D1 (de) 2005-12-22
ATE291445T1 (de) 2005-04-15
AU2002255220B2 (en) 2007-05-31
CN1487967A (zh) 2004-04-07
NO327386B1 (no) 2009-06-22
SK10342003A3 (sk) 2004-02-03
BR0206708A (pt) 2004-02-25
WO2002070594A2 (en) 2002-09-12

Similar Documents

Publication Publication Date Title
CR7034A (es) Portador con fibrinogeno solido y trombina solida
TW200609197A (en) Azeotrope-like trifluoroiodomethane compositions
EP2264117A3 (en) Azeotrope-like compositions of tetrafluoropropene and hydrofluorocarbons
TW200630125A (en) Hemostat
WO2005103191A3 (en) Azeotrope-like trifluoroiodomethane compositions
DE60231419D1 (de) Biologisch abbaubare materialkomponenten
ES2192833T3 (es) Composiciones piezoelectricas ceramica-polimero mejoradas.
WO2001097826A3 (en) Hemostatic compositions, devices and methods
AU2002239402A1 (en) Blowing agent composition and polymeric foam containing a normally-liquid hydrofluorocarbon and carbon dioxide
DE602004032514D1 (de) Biomedizinische schäume
CA2616919A1 (en) Highly porous self-cohered web materials
EP1430911A3 (en) Hemostatic wound dressing and fabric containing aldehyde-modified polysaccharide
TW200503791A (en) Absorbent polymer compositions, medical articles, and methods
BR0102066A (pt) Suporte para fixação de um esfregão de limpeza naextremidade de um cabo
TW200606245A (en) Azeotrope-like compositions of difluoromethane and trifluoroiodomethane
ATE373733T1 (de) Fibrin enthaltende langgestreckte biopolymerstruktur
AR042693A1 (es) Mezclas de agentes de soplado
ES2157742B1 (es) Dispositivo frigorifico en condiciones de funcionamiento variables.
ATE332324T1 (de) Blockcopolymere für chirurgische artikel
ATE388192T1 (de) Treibmittel auf basis von hfc-134a und cyclopentan
BR0105160A (pt) Folha composta hidrofìlica estimável elasticamente
AU7666300A (en) Plastic material and a method for making the same
BR0011948A (pt) Dispositivos absorventes para a evaporação de cálcio
UA74046C2 (en) Solid composition containing solid fibrinogen and solid thrombin which is useful for tissue gluing, tissue sealing and bleeding arrest, method for gluing and sealing tissues, method for bleeding arrest
CO4870783A1 (es) Composicion de poliester