CN114207123A - 脂肪酶变体及其组合物 - Google Patents

脂肪酶变体及其组合物 Download PDF

Info

Publication number
CN114207123A
CN114207123A CN202080045006.4A CN202080045006A CN114207123A CN 114207123 A CN114207123 A CN 114207123A CN 202080045006 A CN202080045006 A CN 202080045006A CN 114207123 A CN114207123 A CN 114207123A
Authority
CN
China
Prior art keywords
lipase
acid
alkyl
variant
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080045006.4A
Other languages
English (en)
Chinese (zh)
Inventor
S.F.克里斯坦森
L.鲍恩斯加德
A.D.富尔顿
A.G.桑德斯特罗姆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes AS
Original Assignee
Novozymes AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes AS filed Critical Novozymes AS
Publication of CN114207123A publication Critical patent/CN114207123A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38627—Preparations containing enzymes, e.g. protease or amylase containing lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01003—Triacylglycerol lipase (3.1.1.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN202080045006.4A 2019-07-02 2020-07-01 脂肪酶变体及其组合物 Pending CN114207123A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19183918.2 2019-07-02
EP19183918 2019-07-02
PCT/EP2020/068459 WO2021001400A1 (en) 2019-07-02 2020-07-01 Lipase variants and compositions thereof

Publications (1)

Publication Number Publication Date
CN114207123A true CN114207123A (zh) 2022-03-18

Family

ID=67145606

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080045006.4A Pending CN114207123A (zh) 2019-07-02 2020-07-01 脂肪酶变体及其组合物

Country Status (3)

Country Link
EP (1) EP3994255A1 (de)
CN (1) CN114207123A (de)
WO (1) WO2021001400A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118871559A (zh) 2021-12-21 2024-10-29 诺维信公司 包含脂肪酶和加强剂的组合物
EP4574943A1 (de) 2023-12-20 2025-06-25 The Procter & Gamble Company Verfahren zum waschen von stoffen bei niedrigen temperaturen
EP4574941A1 (de) 2023-12-20 2025-06-25 The Procter & Gamble Company Verfahren zum waschen von stoffen bei niedrigen temperaturen
EP4574951A1 (de) 2023-12-20 2025-06-25 The Procter & Gamble Company Verfahren zum waschen von stoffen bei niedrigen temperaturen

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170152495A1 (en) * 2014-05-27 2017-06-01 Novozymes A/S Lipase Variants and Polynucleotides Encoding Same
CN107969136A (zh) * 2015-07-06 2018-04-27 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
US20190071620A1 (en) * 2015-07-06 2019-03-07 Novozymes A/S Methods of reducing odor

Family Cites Families (240)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US34584A (en) 1862-03-04 Improvement in rakes for harvesters
US2124526A (en) 1937-04-22 1938-07-26 Timken Roller Bearing Co Diaphragm closure for bearings
US2826551A (en) 1954-01-04 1958-03-11 Simoniz Co Nontangling shampoo
NL114069C (de) 1955-10-27
GB849433A (en) 1957-08-22 1960-09-28 Raymond Woolston Hair washing preparations
NL136759C (de) 1966-02-16
GB1296839A (de) 1969-05-29 1972-11-22
US3646015A (en) 1969-07-31 1972-02-29 Procter & Gamble Optical brightener compounds and detergent and bleach compositions containing same
GB1372034A (en) 1970-12-31 1974-10-30 Unilever Ltd Detergent compositions
US3958581A (en) 1972-05-17 1976-05-25 L'oreal Cosmetic composition containing a cationic polymer and divalent metal salt for strengthening the hair
GB1407997A (en) 1972-08-01 1975-10-01 Procter & Gamble Controlled sudsing detergent compositions
CA1018893A (en) 1972-12-11 1977-10-11 Roger C. Birkofer Mild thickened shampoo compositions with conditioning properties
GB1483591A (en) 1973-07-23 1977-08-24 Novo Industri As Process for coating water soluble or water dispersible particles by means of the fluid bed technique
US3964500A (en) 1973-12-26 1976-06-22 Lever Brothers Company Lusterizing shampoo containing a polysiloxane and a hair-bodying agent
US4422853A (en) 1974-05-16 1983-12-27 L'oreal Hair dyeing compositions containing quaternized polymer
US4217914A (en) 1974-05-16 1980-08-19 L'oreal Quaternized polymer for use as a cosmetic agent in cosmetic compositions for the hair and skin
AT365448B (de) 1975-07-04 1982-01-11 Oreal Kosmetische zubereitung
US4197865A (en) 1975-07-04 1980-04-15 L'oreal Treating hair with quaternized polymers
US4075118A (en) 1975-10-14 1978-02-21 The Procter & Gamble Company Liquid detergent compositions containing a self-emulsified silicone suds controlling agent
GB1590432A (en) 1976-07-07 1981-06-03 Novo Industri As Process for the production of an enzyme granulate and the enzyme granuate thus produced
US4152416A (en) 1976-09-17 1979-05-01 Marra Dorothea C Aerosol antiperspirant compositions delivering astringent salt with low mistiness and dustiness
EP0008830A1 (de) 1978-09-09 1980-03-19 THE PROCTER & GAMBLE COMPANY Schaumunterdrückende Zusammensetzungen und sie enthaltende Reinigungsmittel
US4663158A (en) 1979-07-02 1987-05-05 Clairol Incorporated Hair conditioning composition containing cationic polymer and amphoteric surfactant and method for use
US4507280A (en) 1979-07-02 1985-03-26 Clairol Incorporated Hair conditioning composition and method for use
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
US4529586A (en) 1980-07-11 1985-07-16 Clairol Incorporated Hair conditioning composition and process
GR76237B (de) 1981-08-08 1984-08-04 Procter & Gamble
US4364837A (en) 1981-09-08 1982-12-21 Lever Brothers Company Shampoo compositions comprising saccharides
US4489574A (en) 1981-11-10 1984-12-25 The Procter & Gamble Company Apparatus for highly efficient laundering of textiles
US4489455A (en) 1982-10-28 1984-12-25 The Procter & Gamble Company Method for highly efficient laundering of textiles
GB8401875D0 (en) 1984-01-25 1984-02-29 Procter & Gamble Liquid detergent compositions
DK263584D0 (da) 1984-05-29 1984-05-29 Novo Industri As Enzymholdige granulater anvendt som detergentadditiver
JPS60251906A (ja) 1984-05-30 1985-12-12 Dow Corning Kk シリコ−ン消泡剤組成物の製造方法
US4790856A (en) 1984-10-17 1988-12-13 Colgate-Palmolive Company Softening and anti-static nonionic detergent composition with sulfosuccinamate detergent
JPS61104784A (ja) 1984-10-26 1986-05-23 Suntory Ltd ペルオキシダ−ゼの製造法
US4652392A (en) 1985-07-30 1987-03-24 The Procter & Gamble Company Controlled sudsing detergent compositions
JPH0697997B2 (ja) 1985-08-09 1994-12-07 ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ 新規の酵素的洗浄剤添加物
EG18543A (en) 1986-02-20 1993-07-30 Albright & Wilson Protected enzyme systems
US4762636A (en) 1986-02-28 1988-08-09 Ciba-Geigy Corporation Process for the preparation of granules containing an active substance and to the use thereof as speckles for treating substrates
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
ATE110768T1 (de) 1986-08-29 1994-09-15 Novo Nordisk As Enzymhaltiger reinigungsmittelzusatz.
NZ221627A (en) 1986-09-09 1993-04-28 Genencor Inc Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios
ATE371029T1 (de) 1987-04-06 2007-09-15 Novozymes As Regelung von elektrostatischen interaktionen an metallionen-bindungsstellen zur stabilisierung von proteinen
US4798679A (en) 1987-05-11 1989-01-17 The Procter & Gamble Co. Controlled sudsing stable isotropic liquid detergent compositions
DE3854249T2 (de) 1987-08-28 1996-02-29 Novonordisk As Rekombinante Humicola-Lipase und Verfahren zur Herstellung von rekombinanten Humicola-Lipasen.
JPS6474992A (en) 1987-09-16 1989-03-20 Fuji Oil Co Ltd Dna sequence, plasmid and production of lipase
EP0471265B1 (de) 1988-01-07 1995-10-25 Novo Nordisk A/S Spezifische Protease
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体ｄｎａ、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
GB8806016D0 (en) 1988-03-14 1988-04-13 Danochemo As Encapsulated photoactivator dyes for detergent use
WO1989009259A1 (en) 1988-03-24 1989-10-05 Novo-Nordisk A/S A cellulase preparation
US5776757A (en) 1988-03-24 1998-07-07 Novo Nordisk A/S Fungal cellulase composition containing alkaline CMC-endoglucanase and essentially no cellobiohydrolase and method of making thereof
US4983316A (en) 1988-08-04 1991-01-08 Dow Corning Corporation Dispersible silicone antifoam formulations
US4978471A (en) 1988-08-04 1990-12-18 Dow Corning Corporation Dispersible silicone wash and rinse cycle antifoam formulations
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
JPH02238885A (ja) 1989-03-13 1990-09-21 Oji Paper Co Ltd フェノールオキシダーゼ遺伝子組換えｄｎａ、該組換えｄｎａにより形質転換された微生物、その培養物及びフェノールオキシダーゼの製造方法
GB8915658D0 (en) 1989-07-07 1989-08-23 Unilever Plc Enzymes,their production and use
US5106609A (en) 1990-05-01 1992-04-21 The Procter & Gamble Company Vehicle systems for use in cosmetic compositions
US5104646A (en) 1989-08-07 1992-04-14 The Procter & Gamble Company Vehicle systems for use in cosmetic compositions
JP3220137B2 (ja) 1989-08-25 2001-10-22 ヘンケル・リサーチ・コーポレイション アルカリ性タンパク質分解酵素およびその製造方法
GB8927361D0 (en) 1989-12-04 1990-01-31 Unilever Plc Liquid detergents
EP0528828B2 (de) 1990-04-14 1997-12-03 Genencor International GmbH Alkalische bacillus-lipasen, hierfür codierende dna-sequenzen sowie bacilli, die diese lipasen produzieren
DK115890D0 (da) 1990-05-09 1990-05-09 Novo Nordisk As Enzym
CA2082279C (en) 1990-05-09 2007-09-04 Grethe Rasmussen Cellulase preparation comprising an endoglucanase enzyme
FI903443A7 (fi) 1990-07-06 1992-01-07 Valtion Teknillinen Framstaellning av lackas genom rekombinantorganismer.
DE69129988T2 (de) 1990-09-13 1999-03-18 Novo Nordisk A/S, Bagsvaerd Lipase-varianten
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE69133035T2 (de) 1991-01-16 2003-02-13 The Procter & Gamble Company, Cincinnati Kompakte Waschmittelzusammensetzungen mit hochaktiven Cellulasen
US5292796A (en) 1991-04-02 1994-03-08 Minnesota Mining And Manufacturing Company Urea-aldehyde condensates and melamine derivatives comprising fluorochemical oligomers
EP0511456A1 (de) 1991-04-30 1992-11-04 The Procter & Gamble Company Flüssiges Reinigungsmittel mit einem aromatischen Boratester zur Inhibierung des proteolytischen Enzyms
DK0583420T3 (da) 1991-04-30 1996-07-29 Procter & Gamble Builderholdige flydende detergenter med borsyre-polyol-kompleks til inhibering af proteolytisk enzym
KR100258460B1 (ko) 1991-05-01 2000-06-01 한센 핀 베네드 안정화 효소 및 세제 조성물
US5340735A (en) 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
CA2124787C (en) 1991-12-13 1998-10-27 Frederick E. Hardy Acylated citrate esters as peracid precursors
DK28792D0 (da) 1992-03-04 1992-03-04 Novo Nordisk As Nyt enzym
DK72992D0 (da) 1992-06-01 1992-06-01 Novo Nordisk As Enzym
ES2103477T3 (es) 1992-06-15 1997-09-16 Procter & Gamble Composiciones detergentes liquidas para lavanderia con agente antiespumante de silicona.
DK88892D0 (da) 1992-07-06 1992-07-06 Novo Nordisk As Forbindelse
EP0651794B1 (de) 1992-07-23 2009-09-30 Novozymes A/S MUTIERTE -g(a)-AMYLASE, WASCHMITTEL UND GESCHIRRSPÜLMITTEL
EP1431389A3 (de) 1992-10-06 2004-06-30 Novozymes A/S Zellulase Variante
CZ293163B6 (cs) 1993-02-11 2004-02-18 Genencor International, Inc. Mutanta alfa-amylázy, její použití, kódová DNA pro tuto mutantu, vektor pro expresi, hostitelské buňky, čisticí prostředek a prostředek pro zkapalnění škrobu
ATE287946T1 (de) 1993-04-27 2005-02-15 Genencor Int Neuartige lipasevarianten zur verwendung in reinigungsmitteln
DK52393D0 (de) 1993-05-05 1993-05-05 Novo Nordisk As
FR2704860B1 (fr) 1993-05-05 1995-07-13 Pasteur Institut Sequences de nucleotides du locus cryiiia pour le controle de l'expression de sequences d'adn dans un hote cellulaire.
US5486303A (en) 1993-08-27 1996-01-23 The Procter & Gamble Company Process for making high density detergent agglomerates using an anhydrous powder additive
JP2859520B2 (ja) 1993-08-30 1999-02-17 ノボ ノルディスク アクティーゼルスカブ リパーゼ及びそれを生産する微生物及びリパーゼ製造方法及びリパーゼ含有洗剤組成物
CN1189558C (zh) 1993-10-08 2005-02-16 诺沃奇梅兹有限公司 淀粉酶变体
EP0724631A1 (de) 1993-10-13 1996-08-07 Novo Nordisk A/S H 2?o 2?-stabile peroxidasevarianten
US5360569A (en) 1993-11-12 1994-11-01 Lever Brothers Company, Division Of Conopco, Inc. Activation of bleach precursors with catalytic imine quaternary salts
US5360568A (en) 1993-11-12 1994-11-01 Lever Brothers Company, Division Of Conopco, Inc. Imine quaternary salts as bleach catalysts
JPH07143883A (ja) 1993-11-24 1995-06-06 Showa Denko Kk リパーゼ遺伝子及び変異体リパーゼ
DE4343591A1 (de) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
EP0746618B1 (de) 1994-02-22 2002-08-21 Novozymes A/S Methode zur herstellung einer variante eines lipolytischen enzymes
WO1995023221A1 (en) 1994-02-24 1995-08-31 Cognis, Inc. Improved enzymes and detergents containing them
WO1995024471A1 (en) 1994-03-08 1995-09-14 Novo Nordisk A/S Novel alkaline cellulases
NL9401048A (nl) 1994-03-31 1995-11-01 Stichting Scheikundig Onderzoe Haloperoxidasen.
JP3851656B2 (ja) 1994-05-04 2006-11-29 ジェネンコア インターナショナル インコーポレーテッド 改善された界面活性剤耐性を有するリパーゼ
WO1995033836A1 (en) 1994-06-03 1995-12-14 Novo Nordisk Biotech, Inc. Phosphonyldipeptides useful in the treatment of cardiovascular diseases
WO1995035381A1 (en) 1994-06-20 1995-12-28 Unilever N.V. Modified pseudomonas lipases and their use
WO1996000292A1 (en) 1994-06-23 1996-01-04 Unilever N.V. Modified pseudomonas lipases and their use
ATE294871T1 (de) 1994-06-30 2005-05-15 Novozymes Biotech Inc Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren
US5879584A (en) 1994-09-10 1999-03-09 The Procter & Gamble Company Process for manufacturing aqueous compositions comprising peracids
US5691297A (en) 1994-09-20 1997-11-25 The Procter & Gamble Company Process for making a high density detergent composition by controlling agglomeration within a dispersion index
US5516448A (en) 1994-09-20 1996-05-14 The Procter & Gamble Company Process for making a high density detergent composition which includes selected recycle streams for improved agglomerate
US5489392A (en) 1994-09-20 1996-02-06 The Procter & Gamble Company Process for making a high density detergent composition in a single mixer/densifier with selected recycle streams for improved agglomerate properties
DE69535733T2 (de) 1994-10-06 2009-04-23 Novozymes A/S Ein enzympräparat mit endoglucanase aktivität
BE1008998A3 (fr) 1994-10-14 1996-10-01 Solvay Lipase, microorganisme la produisant, procede de preparation de cette lipase et utilisations de celle-ci.
BR9509525A (pt) 1994-10-26 1995-10-26 Novo Nordisk As Construção de dna vetor de expressão recombinante célula processo para produzir a enzima que exibe atividade lipolítica enzima que exibe atividade lipolítica preparação de enzima aditivo de detergente e composição de detergente
JPH10507639A (ja) 1994-10-26 1998-07-28 ノボ ノルディスク アクティーゼルスカブ 酵素界面活性剤組成物
US5534179A (en) 1995-02-03 1996-07-09 Procter & Gamble Detergent compositions comprising multiperacid-forming bleach activators
AR000862A1 (es) 1995-02-03 1997-08-06 Novozymes As Variantes de una ó-amilasa madre, un metodo para producir la misma, una estructura de adn y un vector de expresion, una celula transformada por dichaestructura de adn y vector, un aditivo para detergente, composicion detergente, una composicion para lavado de ropa y una composicion para la eliminacion del
JPH08228778A (ja) 1995-02-27 1996-09-10 Showa Denko Kk 新規なリパーゼ遺伝子及びそれを用いたリパーゼの製造方法
US5574005A (en) 1995-03-07 1996-11-12 The Procter & Gamble Company Process for producing detergent agglomerates from high active surfactant pastes having non-linear viscoelastic properties
EP0815209B2 (de) 1995-03-17 2015-02-25 Novozymes A/S Neue endoglukanase
US5569645A (en) 1995-04-24 1996-10-29 The Procter & Gamble Company Low dosage detergent composition containing optimum proportions of agglomerates and spray dried granules for improved flow properties
ATE429490T1 (de) 1995-05-05 2009-05-15 Novozymes As Protease-varianten und verbindungen
US5597936A (en) 1995-06-16 1997-01-28 The Procter & Gamble Company Method for manufacturing cobalt catalysts
US5565422A (en) 1995-06-23 1996-10-15 The Procter & Gamble Company Process for preparing a free-flowing particulate detergent composition having improved solubility
WO1997007202A1 (en) 1995-08-11 1997-02-27 Novo Nordisk A/S Novel lipolytic enzymes
AU6414196A (en) 1995-07-14 1997-02-18 Novo Nordisk A/S A modified enzyme with lipolytic activity
JP2002507111A (ja) 1995-07-14 2002-03-05 ノボ ノルディスク アクティーゼルスカブ クルブラリア・ベルルクロサからのハロペルオキシダーゼ及びそれをコードする核酸
DE19528059A1 (de) 1995-07-31 1997-02-06 Bayer Ag Wasch- und Reinigungsmittel mit Iminodisuccinaten
US6008029A (en) 1995-08-25 1999-12-28 Novo Nordisk Biotech Inc. Purified coprinus laccases and nucleic acids encoding the same
US5576282A (en) 1995-09-11 1996-11-19 The Procter & Gamble Company Color-safe bleach boosters, compositions and laundry methods employing same
US5750122A (en) 1996-01-16 1998-05-12 The Procter & Gamble Company Compositions for treating hair or skin
US5674478A (en) 1996-01-12 1997-10-07 The Procter & Gamble Company Hair conditioning compositions
CN1209842A (zh) 1996-01-24 1999-03-03 诺沃诺尔迪斯克生物技术有限公司 编码具有犁头霉属脂酶活性的多肽的核酸
DE69733519T2 (de) 1996-03-04 2005-11-03 General Electric Co. Blockcopolymere auf basis von silikonen und aminopolyalkylenoxiden
MA24137A1 (fr) 1996-04-16 1997-12-31 Procter & Gamble Fabrication d'agents de surface ramifies .
US5763385A (en) 1996-05-14 1998-06-09 Genencor International, Inc. Modified α-amylases having altered calcium binding properties
AU3938997A (en) 1996-08-26 1998-03-19 Novo Nordisk A/S A novel endoglucanase
US5817614A (en) 1996-08-29 1998-10-06 Procter & Gamble Company Color-safe bleach boosters, compositions and laundry methods employing same
BR9711479B1 (pt) 1996-09-17 2009-08-11 variante de celulase tendo uma resistência aumentada a tensìdeo de ánion.
CA2265734A1 (en) 1996-10-08 1998-04-16 Novo Nordisk A/S Diaminobenzoic acid derivatives as dye precursors
BR9712360A (pt) 1996-10-18 2001-06-19 Procter & Gamble Composições detergentes
US6300116B1 (en) 1996-11-04 2001-10-09 Novozymes A/S Modified protease having improved autoproteolytic stability
BR9712473B1 (pt) 1996-11-04 2009-08-11 variantes de subtilase e composições.
US5753599A (en) 1996-12-03 1998-05-19 Lever Brothers Company, Division Of Conopco, Inc. Thiadiazole dioxides as bleach enhancers
WO1998034946A1 (en) 1997-02-12 1998-08-13 Massachusetts Institute Of Technology Daxx, a novel fas-binding protein that activates jnk and apoptosis
AU731577B2 (en) 1997-03-07 2001-04-05 Procter & Gamble Company, The Bleach compositions containing metal bleach catalyst, and bleach activators and/or organic percarboxylic acids
AU732147B2 (en) 1997-03-07 2001-04-12 Procter & Gamble Company, The Bleach compositions
US6218351B1 (en) 1998-03-06 2001-04-17 The Procter & Gamble Compnay Bleach compositions
CN1263759C (zh) 1997-03-07 2006-07-12 宝洁公司 制备交联桥大环化合物的改进方法
EP0884352B1 (de) 1997-06-11 2001-09-05 Kuraray Co., Ltd. Wasserlöslicher Folie
ATE385254T1 (de) 1997-08-29 2008-02-15 Novozymes As Proteasevarianten und zusammensetzungen
AR017331A1 (es) 1997-10-13 2001-09-05 Novozymes As Polipeptidos mutantes de alfa-amilasas, aditivo para detergentes y composiciones detergentes que los comprenden.
WO1999027083A1 (en) 1997-11-24 1999-06-03 Novo Nordisk A/S PECTIN DEGRADING ENZYMES FROM $i(BACILLUS LICHENIFORMIS)
US6124127A (en) 1997-11-24 2000-09-26 Novo Nordisk A/S Pectate lyase
EP1032658B1 (de) 1997-11-24 2012-06-27 Novozymes A/S Pectatlyase
GB9807477D0 (en) 1998-04-07 1998-06-10 Unilever Plc Coloured granular composition for use in particulate detergent compositions
US5955310A (en) 1998-02-26 1999-09-21 Novo Nordisk Biotech, Inc. Methods for producing a polypeptide in a bacillus cell
ATE272104T1 (de) 1998-05-18 2004-08-15 Ciba Sc Holding Ag Wasserlösliche granulate von phthalocyaninverbindungen
US6207782B1 (en) 1998-05-28 2001-03-27 Cromption Corporation Hydrophilic siloxane latex emulsions
EP2261359B1 (de) 1998-06-10 2014-08-20 Novozymes A/S Mannanasen
PH11999002190B1 (en) 1998-09-01 2007-08-06 Unilever Nv Composition and method for bleaching a substrate
DK1124949T3 (da) 1998-10-26 2006-11-06 Novozymes As Konstruktion og screening af et DNA-bibliotek af interesse i trådformede svampeceller
AU2026100A (en) 1998-11-30 2000-06-19 Procter & Gamble Company, The Process for preparing cross-bridged tetraaza macrocycles
CA2355580C (en) 1998-12-18 2011-03-15 Novozymes A/S Subtilase enzymes of the i-s1 and i-s2 sub-groups having an additional amino acid residue in the active site loop region
CN100482801C (zh) 1999-03-22 2009-04-29 诺沃奇梅兹有限公司 用于在真菌细胞中表达基因的启动子
US6939702B1 (en) 1999-03-31 2005-09-06 Novozymes A/S Lipase variant
EP2206786A1 (de) 1999-08-31 2010-07-14 Novozymes A/S Neue Proteasen und Varianten davon
CA2394971C (en) 1999-12-15 2016-01-19 Novozymes A/S Subtilase variants having an improved wash performance on egg stains
PL203212B1 (pl) 2000-02-08 2009-09-30 Dsm Ip Assets Bv Zastosowanie trwałej w kwasie proteazy w karmie zwierzęcej oraz w wytwarzaniu kompozycji do stosowania w karmie zwierzęcej, dodatek do karmy zwierzęcej, kompozycja karmy zwierzęcej i sposób obróbki białek roślinnych
AU2001240473A1 (en) 2000-03-08 2001-09-17 Novozymes A/S Variants with altered properties
WO2001079463A2 (en) 2000-04-14 2001-10-25 Novozymes A/S Nucleic acids encoding polypeptides having haloperoxidase activity
WO2001079465A2 (en) 2000-04-14 2001-10-25 Novozymes A/S Nucleic acids encoding polypeptides having haloperoxidase activity
AU2001246404A1 (en) 2000-04-14 2001-10-30 Novozymes A/S Polypeptides having haloperoxidase activity
WO2001079464A2 (en) 2000-04-14 2001-10-25 Novozymes A/S Nucleic acids encoding polypeptides having haloperoxidase activity
MXPA03000435A (es) 2000-07-19 2004-04-02 Novozymes As Variantes de enzimas que degradan la pared celular.
CA2423285C (en) 2000-07-27 2009-12-22 Ge Bayer Silicones Gmbh & Co. Kg Polyammonium-polysiloxane compounds, methods for the production and use thereof
US7041767B2 (en) 2000-07-27 2006-05-09 Ge Bayer Silicones Gmbh & Co. Kg Polysiloxane polymers, method for their production and the use thereof
DE10036533B4 (de) 2000-07-27 2005-02-03 Ge Bayer Silicones Gmbh & Co. Kg Verwendung von polyquarternären Polysiloxanen als waschbeständige hydrophile Weichmacher
EP1370648A2 (de) 2000-08-01 2003-12-17 Novozymes A/S Alpha-amylase-mutanten mit veränderten eigenschaften
CN1337553A (zh) 2000-08-05 2002-02-27 李海泉 地下观光游乐园
WO2002016547A2 (en) 2000-08-21 2002-02-28 Novozymes A/S Subtilase enzymes
CN100340648C (zh) 2000-10-27 2007-10-03 宝洁公司 稳定的液体组合物
DE10058645A1 (de) 2000-11-25 2002-05-29 Clariant Gmbh Verwendung von cyclischen Zuckerketonen als Katalysatoren für Persauerstoffverbindungen
AU2302002A (en) 2000-11-27 2002-06-03 Novozymes As Automated mechanical stress assay for screening cleaning ingredients
US7611882B2 (en) 2001-05-14 2009-11-03 Novozymes A/S Detergent compositions comprising Bacillus subtilis pectate lyases
US7041488B2 (en) 2001-06-06 2006-05-09 Novozymes A/S Endo-beta-1,4-glucanase from bacillus
DK200101090A (da) 2001-07-12 2001-08-16 Novozymes As Subtilase variants
EP1421187B1 (de) 2001-07-27 2007-10-10 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Systeme zur stellengerichteten in-vivo-mutagenese mit oligonukleotiden
GB0120160D0 (en) 2001-08-20 2001-10-10 Unilever Plc Photobleach speckle and laundry detergent compositions containing it
BRPI0211408B1 (pt) 2001-08-20 2017-01-31 Unilever Nv composição granular, composição detergente de lavagem de roupa particulada, e, processo para a fabricação de uma composição granular
US6482969B1 (en) 2001-10-24 2002-11-19 Dow Corning Corporation Silicon based quaternary ammonium functional compositions and methods for making them
US6607717B1 (en) 2001-10-24 2003-08-19 Dow Corning Corporation Silicon based quaternary ammonium functional compositions and their applications
DE10162728A1 (de) 2001-12-20 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus gibsonii (DSM 14393) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease
WO2003095638A1 (en) 2002-05-14 2003-11-20 Novozymes A/S Pectate lyase variants
WO2004003186A2 (en) 2002-06-26 2004-01-08 Novozymes A/S Subtilases and subtilase variants having altered immunogenicity
EP1534814B1 (de) 2002-09-04 2006-05-24 Ciba SC Holding AG Formulierungen enthaltend wasserlösliche granulate
KR100554479B1 (ko) 2002-09-11 2006-03-03 씨제이라이온 주식회사 염착 얼룩 방지 세탁용 착염
TWI319007B (en) 2002-11-06 2010-01-01 Novozymes As Subtilase variants
GB0300808D0 (en) 2003-01-14 2003-02-12 Unilever Plc Home and personal care compositions with lubricants
US9068234B2 (en) 2003-01-21 2015-06-30 Ptc Therapeutics, Inc. Methods and agents for screening for compounds capable of modulating gene expression
US7022656B2 (en) 2003-03-19 2006-04-04 Monosol, Llc. Water-soluble copolymer film packet
BRPI0409992A (pt) 2003-05-07 2006-05-09 Novozymes As enzima subtilase, polinucleotìdeo isolado, construção de ácido nucleico, vetor de expressão recombinante, célula hospedeira recombinante, método para produzir a subtilase, composição limpadora ou detergente, usos de uma subtilase e de uma composição limpadora ou detergente, e, métodos para limpar ou lavar louças, lavar uma superfìcie dura ou lavar roupas e para remover manchas de ovo de uma superfìcie dura ou de roupas para lavar
WO2005040372A1 (en) 2003-10-23 2005-05-06 Novozymes A/S Protease with improved stability in detergents
GB0325432D0 (en) 2003-10-31 2003-12-03 Unilever Plc Ligand and complex for catalytically bleaching a substrate
US20050113246A1 (en) 2003-11-06 2005-05-26 The Procter & Gamble Company Process of producing an organic catalyst
WO2005052146A2 (en) 2003-11-19 2005-06-09 Genencor International, Inc. Serine proteases, nucleic acids encoding serine enzymes and vectors and host cells incorporating same
EP2292743B1 (de) 2003-12-03 2013-08-21 Danisco US Inc. Perhydrolase
US7754460B2 (en) 2003-12-03 2010-07-13 Danisco Us Inc. Enzyme for the production of long chain peracid
US7208459B2 (en) 2004-06-29 2007-04-24 The Procter & Gamble Company Laundry detergent compositions with efficient hueing dye
CA2575592C (en) 2004-09-23 2013-11-12 Unilever Plc Laundry treatment compositions comprising an anthraquinone hydrophobic dye
MX2007007494A (es) 2004-12-23 2007-08-15 Novozymes As Variantes de alfa-amilasa.
PL1712610T3 (pl) 2005-02-22 2014-04-30 Procter & Gamble Kompozycje deteregentu
EP1712611B1 (de) 2005-02-22 2014-10-22 The Procter and Gamble Company Waschmittelzusammensetzungen
US20070041929A1 (en) 2005-06-16 2007-02-22 Torgerson Peter M Hair conditioning composition comprising silicone polymers containing quaternary groups
JP2009500023A (ja) 2005-07-08 2009-01-08 ノボザイムス アクティーゼルスカブ サブチラーゼ変異体
KR20080066921A (ko) 2005-10-12 2008-07-17 제넨코 인터내셔날 인코포레이티드 저장-안정성 중성 메탈로프로테아제의 용도 및 제조
US9427391B2 (en) 2006-01-09 2016-08-30 The Procter & Gamble Company Personal care compositions containing cationic synthetic copolymer and a detersive surfactant
US8187854B2 (en) 2006-01-23 2012-05-29 Novozymes A/S Lipase variants
AR059154A1 (es) 2006-01-23 2008-03-12 Procter & Gamble Una composicion que comprende una lipasa y un catalizador de blanqueador
US20070191247A1 (en) 2006-01-23 2007-08-16 The Procter & Gamble Company Detergent compositions
CA2635947A1 (en) 2006-01-23 2007-08-02 The Procter & Gamble Company Enzyme and photobleach containing compositions
US8022027B2 (en) 2006-01-23 2011-09-20 The Procter & Gamble Company Composition comprising a lipase and a bleach catalyst
US20070286837A1 (en) 2006-05-17 2007-12-13 Torgerson Peter M Hair care composition comprising an aminosilicone and a high viscosity silicone copolymer emulsion
EP2076591A2 (de) 2006-10-20 2009-07-08 Danisco US, INC., Genencor Division Polyol-oxidasen
EP2192169B1 (de) 2007-01-19 2012-05-09 The Procter & Gamble Company Wäschepflegezusammensetzung mit Bleichmittel für Cellulosesubstrate
CN101617035A (zh) 2007-02-20 2009-12-30 诺维信公司 用于洗衣的酶泡沫处理
CN101675160A (zh) 2007-04-30 2010-03-17 丹尼斯科美国公司 蛋白质水解产物稳定金属蛋白酶洗涤剂制剂的用途
EP2155869A2 (de) 2007-05-30 2010-02-24 Danisco US, INC., Genencor Division Varianten einer alpha-amylase mit verbesserten produktionsniveaus bei fermentationsverfahren
CA2687560C (en) 2007-06-11 2013-05-14 The Procter & Gamble Company Benefit agent containing delivery particle
PL2014756T3 (pl) 2007-07-02 2011-09-30 Procter & Gamble Kompozycja piorąca woreczka wieloprzegródkowego
DE102007038031A1 (de) 2007-08-10 2009-06-04 Henkel Ag & Co. Kgaa Mittel enthaltend Proteasen
GB0719161D0 (en) 2007-10-01 2007-11-07 Unilever Plc Improvements relating to fabrick treatment compositions
KR20100088675A (ko) 2007-11-05 2010-08-10 다니스코 유에스 인크. 변경된 특성을 지닌 바실러스 종 ｔｓ-23 알파-아밀라아제의 변이체
WO2009095425A1 (en) 2008-02-01 2009-08-06 Novozymes A/S Liquid enzyme composition
US20090209447A1 (en) 2008-02-15 2009-08-20 Michelle Meek Cleaning compositions
AR070490A1 (es) 2008-02-29 2010-04-07 Novozymes As Polipeptidos de thermomyces lanuginosus con actividad de lipasa y polinucleotidos que los codifican
CA2715795A1 (en) 2008-03-26 2009-10-01 The Procter & Gamble Company Delivery particle having a shell of water insoluble inorganic meterial
WO2010034736A1 (en) 2008-09-25 2010-04-01 Unilever Plc Liquid detergents
CN102648277B (zh) 2009-09-25 2015-05-20 诺维信公司 蛋白酶变体的用途
WO2011036263A1 (en) 2009-09-25 2011-03-31 Novozymes A/S Subtilase variants
US9896673B2 (en) 2010-02-10 2018-02-20 Novozymes A/S Compositions of high stability alpha amylase variants
GB2477914B (en) 2010-02-12 2012-01-04 Univ Newcastle Compounds and methods for biofilm disruption and prevention
MX2013009178A (es) 2011-02-16 2013-08-29 Novozymes As Composiciones detergentes que comprenden metaloproteasas.
WO2013001087A2 (en) 2011-06-30 2013-01-03 Novozymes A/S Method for screening alpha-amylases
ES2834102T3 (es) 2011-06-30 2021-06-16 Novozymes As Variantes de alfa-amilasa

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170152495A1 (en) * 2014-05-27 2017-06-01 Novozymes A/S Lipase Variants and Polynucleotides Encoding Same
CN107969136A (zh) * 2015-07-06 2018-04-27 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
US20190071620A1 (en) * 2015-07-06 2019-03-07 Novozymes A/S Methods of reducing odor

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GUANLIN LI等: "Enhancing the Thermostability of Rhizomucor miehei Lipase with a Limited Screening Library by Rational-Design Point Mutations and Disulfide Bonds", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 3 November 2017 (2017-11-03), pages 1 - 16 *
张黎;赵鹤云;徐莉;刘云;闫云君;: "解脂耶氏酵母脂肪酶基因lip1的克隆、密码子优化及功能表达", 微生物学报, no. 07, 4 July 2010 (2010-07-04) *

Also Published As

Publication number Publication date
EP3994255A1 (de) 2022-05-11
WO2021001400A1 (en) 2021-01-07

Similar Documents

Publication Publication Date Title
CN107109382B (zh) 洗涤剂组合物、脂肪酶变体以及编码其的多核苷酸
EP2997139B1 (de) Reinigungsmittelzusammensetzung die humicola lanuginosa lipase variante enthalten .
CN107995922B (zh) 在亚硫酸盐的存在下具有改进的稳定性的洗涤剂组合物
EP3201305B1 (de) Lipasevarianten und polynucleotide zur codierung davon
CN107960104A (zh) 减少气味的方法
EP3485008B1 (de) Lipasevarianten, polynukleotide zur codierung davon und verwendung davon
EP3688150B1 (de) Lipasevarianten und mikrokapselzusammensetzungen, die solche lipasevarianten enthalten
CN108431217B (zh) 用于产生脂肪酶的方法
CN107922930A (zh) 减少气味的方法
CN121406607A (zh) 脂肪酶变体以及编码它们的多核苷酸
CN107969136B (zh) 脂肪酶变体以及编码它们的多核苷酸
CN110651038B (zh) 包含脂肪酶和亚硫酸根的组合物
CN114207123A (zh) 脂肪酶变体及其组合物
CN106459936A (zh) 用于修饰脂肪酶的方法
CN111788305A (zh) 脂肪酶变体及其组合物
CN111868239A (zh) 脂肪酶、脂肪酶变体及其组合物
CN108012543B (zh) 具有脂肪酶活性的多肽和编码它们的多核苷酸
CN106715465B (zh) 具有脂肪酶活性的多肽和编码它们的多核苷酸

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20220318

WD01 Invention patent application deemed withdrawn after publication