CR10207A - "derivados de acido acético benzo (f) isoindol-2-ilfenil como receptores agonistas de ep4" - Google Patents

"derivados de acido acético benzo (f) isoindol-2-ilfenil como receptores agonistas de ep4"

Info

Publication number
CR10207A
CR10207A CR10207A CR10207A CR10207A CR 10207 A CR10207 A CR 10207A CR 10207 A CR10207 A CR 10207A CR 10207 A CR10207 A CR 10207A CR 10207 A CR10207 A CR 10207A
Authority
CR
Costa Rica
Prior art keywords
ilfenil
isoindol
derivatives
acetic acid
acid benzo
Prior art date
Application number
CR10207A
Other languages
English (en)
Inventor
Andrew Billinton
Nicholas Maughan Clayton
Gerard Martin Paul Giblin
Mark Patrick Healy
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37944208&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR10207(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0602237A external-priority patent/GB0602237D0/en
Priority claimed from GB0608976A external-priority patent/GB0608976D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CR10207A publication Critical patent/CR10207A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
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  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)

Abstract

Un compuesto de la fórmula (I) o uno de sus derivados farmacéuticamente aceptables, en la que, R1, R2, R3, R4, R5, R6 , x e Y son como se definen en la memoria descriptiva; un procedimiento para preparar dichos compeustos; una composición farmacéutica que comprende dichos compuestos, y el uso de dichos compuestos en medicina.
CR10207A 2006-02-03 2008-08-14 "derivados de acido acético benzo (f) isoindol-2-ilfenil como receptores agonistas de ep4" CR10207A (es)

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GB0602237A GB0602237D0 (en) 2006-02-03 2006-02-03 Novel compounds
GB0608976A GB0608976D0 (en) 2006-05-05 2006-05-05 Novel compounds

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KR (1) KR20080097417A (es)
AR (1) AR059282A1 (es)
AU (1) AU2007211484A1 (es)
BR (1) BRPI0708024A2 (es)
CA (1) CA2640277A1 (es)
CR (1) CR10207A (es)
EA (1) EA200870224A1 (es)
ES (1) ES2390491T3 (es)
IL (1) IL192934A0 (es)
MA (1) MA30209B1 (es)
NO (1) NO20083448L (es)
PE (1) PE20070949A1 (es)
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GB0623203D0 (en) * 2006-11-21 2007-01-03 Glaxo Group Ltd Novel compounds
CN101686985A (zh) 2007-05-08 2010-03-31 国立大学法人浜松医科大学 含有ep4激动剂的细胞毒性t细胞的活化剂
GB0721611D0 (en) 2007-11-02 2007-12-12 Glaxo Group Ltd Novel compounds
CN103012111B (zh) * 2012-09-12 2016-01-13 衢州学院 一种2,4,5-三氟苯乙酸的制备方法
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AR059282A1 (es) 2008-03-19
US20110201663A1 (en) 2011-08-18
WO2007088190A1 (en) 2007-08-09
CA2640277A1 (en) 2007-08-09
AU2007211484A1 (en) 2007-08-09
EP1979316B1 (en) 2012-07-11
JP2013082734A (ja) 2013-05-09
KR20080097417A (ko) 2008-11-05
TW200808722A (en) 2008-02-16
MA30209B1 (fr) 2009-02-02
EP1979316A1 (en) 2008-10-15
EP2457897A1 (en) 2012-05-30
PE20070949A1 (es) 2007-11-22
NO20083448L (no) 2008-10-23
EA200870224A1 (ru) 2009-02-27
SG169380A1 (en) 2011-03-30
IL192934A0 (en) 2009-02-11
UY30121A1 (es) 2007-08-31
BRPI0708024A2 (pt) 2011-05-17
ES2390491T3 (es) 2012-11-13
JP2009525309A (ja) 2009-07-09
JP5250427B2 (ja) 2013-07-31
US8252833B2 (en) 2012-08-28

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