NO20083448L - Benzo(f)isoindol-2-ylfenyleddiksyrederivater som EP4 receptoragonister - Google Patents

Benzo(f)isoindol-2-ylfenyleddiksyrederivater som EP4 receptoragonister

Info

Publication number: NO20083448L
Authority: NO; Norway
Prior art keywords: isoindol; benzo; acid derivatives; receptor agonists; ylphenylacetic
Prior art date: 2006-02-03

Application number

NO20083448A

Other languages

English (en)

Norwegian (no)

Inventor

Gerard Martin Paul Giblin

Mark Patrick Healy

Andrew Billinton

Nicholas Maughan Clayton

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-02-03

Filing date

2008-08-07

Publication date

2008-10-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37944208&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20083448(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-02-03 Priority claimed from GB0602237A external-priority patent/GB0602237D0/en

2006-05-05 Priority claimed from GB0608976A external-priority patent/GB0608976D0/en

2008-08-07 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2008-10-23 Publication of NO20083448L publication Critical patent/NO20083448L/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
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NO20083448A 2006-02-03 2008-08-07 Benzo(f)isoindol-2-ylfenyleddiksyrederivater som EP4 receptoragonister NO20083448L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0602237A GB0602237D0 (en)	2006-02-03	2006-02-03	Novel compounds
GB0608976A GB0608976D0 (en)	2006-05-05	2006-05-05	Novel compounds
PCT/EP2007/050992 WO2007088190A1 (en)	2006-02-03	2007-02-01	Benzo (f) isoindol-2-ylphenyl acetic acid derivatives as ep4 receptor agonists

Publications (1)

Publication Number	Publication Date
NO20083448L true NO20083448L (no)	2008-10-23

Family

ID=37944208

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20083448A NO20083448L (no)	2006-02-03	2008-08-07	Benzo(f)isoindol-2-ylfenyleddiksyrederivater som EP4 receptoragonister

Country Status (19)

Country	Link
US (1)	US8252833B2 (es)
EP (2)	EP2457897A1 (es)
JP (2)	JP5250427B2 (es)
KR (1)	KR20080097417A (es)
AR (1)	AR059282A1 (es)
AU (1)	AU2007211484A1 (es)
BR (1)	BRPI0708024A2 (es)
CA (1)	CA2640277A1 (es)
CR (1)	CR10207A (es)
EA (1)	EA200870224A1 (es)
ES (1)	ES2390491T3 (es)
IL (1)	IL192934A0 (es)
MA (1)	MA30209B1 (es)
NO (1)	NO20083448L (es)
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SG (1)	SG169380A1 (es)
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Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2007136790A2 (en) *	2006-05-18	2007-11-29	Mannkind Corporation	Intracellular kinase inhibitors
GB0615111D0 (en) *	2006-07-28	2006-09-06	Glaxo Group Ltd	Novel compounds
GB0620619D0 (en) *	2006-10-17	2006-11-29	Glaxo Group Ltd	Novel compounds
GB0623203D0 (en) *	2006-11-21	2007-01-03	Glaxo Group Ltd	Novel compounds
AU2008246579A1 (en)	2007-05-08	2008-11-13	National University Corporation, Hamamatsu University School Of Medicine	Cytotoxic T cell activator comprising EP4 agonist
GB0721611D0 (en)	2007-11-02	2007-12-12	Glaxo Group Ltd	Novel compounds
CN103012111B (zh) *	2012-09-12	2016-01-13	衢州学院	一种2,4,5-三氟苯乙酸的制备方法
CN110003129B (zh) *	2019-04-18	2021-04-06	济南立德医药技术有限公司	一种佐米曲普坦中间体的制备方法
WO2021082705A1 (zh)	2019-10-29	2021-05-06	宁波舜宇光电信息有限公司	摄像模组及其光学镜头、光学镜片和制造方法以及大广角摄像模组的组装方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT947165B (it)	1971-05-17	1973-05-21	Grefco	Composizioni e processo per la eliminazione selettiva di prodot ti oleosi dall acqua
JPH10265454A (ja)	1997-01-27	1998-10-06	Ono Pharmaceut Co Ltd	３，７−ジチアプロスタン酸誘導体、それらの製造方法およびそれらを有効成分として含有する薬剤
AUPO713297A0 (en)	1997-06-02	1997-06-26	Fujisawa Pharmaceutical Co., Ltd.	Oxazole compound
US6043275A (en)	1998-04-16	2000-03-28	Ono Pharmaceutical Co., Ltd.	3,7-dithiaprostanoic acid derivative
TWI249520B (en)	1998-07-15	2006-02-21	Ono Pharmaceutical Co	5-Thia-omega-substituted phenyl prostaglandin E derivatives, method for producing the same and medicines containing the same as the active ingredient
US6586468B1 (en)	1998-09-14	2003-07-01	Ono Pharmaceutical Co., Ltd.	ω-substituted phenyl-prostaglandin E derivatives and drugs containing the same as the active ingredient
AUPP608898A0 (en)	1998-09-23	1998-10-15	Fujisawa Pharmaceutical Co., Ltd.	New use of prostaglandin E2 antagonists
US6437146B1 (en)	1998-09-25	2002-08-20	Fujisawa Pharmaceutical Co., Ltd.	Oxazole compounds as prostaglandin e2 agonists or antagonists
JP2002527393A (ja)	1998-10-15	2002-08-27	メルクエンドカムパニーインコーポレーテッド	骨吸収阻害方法
AU6836200A (en)	1999-08-10	2001-03-05	Glaxo Group Limited	Use of ep4 receptor ligands in the treatment of, inter alia, neuropathic pain and colon cancer
GB0030541D0 (en)	2000-12-14	2001-01-31	Glaxo Group Ltd	Medical uses
GB0031315D0 (en)	2000-12-21	2001-02-07	Glaxo Group Ltd	Indole derivatives
GB0031295D0 (en)	2000-12-21	2001-01-31	Glaxo Group Ltd	Naphthalene derivatives
GB0031302D0 (en)	2000-12-21	2001-01-31	Glaxo Group Ltd	Napthalene derivatives
GB0103269D0 (en)	2001-02-09	2001-03-28	Glaxo Group Ltd	Napthalene derivatives
CA2478653A1 (en)	2002-03-18	2003-09-25	Pfizer Products Inc.	Methods of treatment with selective ep4 receptor agonists
CN100579518C (zh)	2002-04-12	2010-01-13	美国辉瑞有限公司	Ep4受体配体在制备治疗il-6相关疾病的药物中的应用
US7419999B2 (en)	2002-06-10	2008-09-02	Applied Research Systems Ars Holding N.V.	Gamma lactams as prostaglandin agonists and use thereof
JP2005531638A (ja)	2002-07-01	2005-10-20	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	Ｈｃｖｎｓ５ｂポリメラーゼ阻害剤
AU2003275838A1 (en)	2002-10-25	2004-05-13	Beunard, Jean-Luc	Pyrrolidin-2-on derivatives as ep4 receptor agonists
US7053085B2 (en)	2003-03-26	2006-05-30	Merck & Co. Inc.	EP4 receptor agonist, compositions and methods thereof
DE602004013938D1 (de)	2003-01-29	2008-07-03	Asterand Uk Ltd	Hemmstoffe des ep4-rezeptors
KR100747401B1 (ko)	2003-09-03	2007-08-08	화이자 인코포레이티드	프로스타글란딘 ｅ2 길항제로서의 페닐 또는 피리딜 아미드 화합물
GB0324269D0 (en)	2003-10-16	2003-11-19	Pharmagene Lab Ltd	EP4 receptor antagonists
WO2005080367A1 (en)	2004-02-12	2005-09-01	Pharmagene Laboratories Limited	Ep2 receptor agonists
JP4054369B2 (ja)	2004-05-04	2008-02-27	ファイザー株式会社	オルト置換アリールまたはヘテロアリールアミド化合物
MXPA06011555A (es)	2004-05-04	2006-12-15	Pfizer	Compuestos de metil-aril o heteroaril-amida sustituida.
WO2005116010A1 (en)	2004-05-26	2005-12-08	Merck Frosst Canada Ltd.	Ep4 receptor agonist, compositions and methods thereof
WO2006122403A1 (en)	2005-05-19	2006-11-23	Merck Frosst Canada Ltd.	Quinoline derivatives as ep4 antagonists
GB0602900D0 (en) *	2006-02-13	2006-03-22	Glaxo Group Ltd	Novel Compounds

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Publication number	Publication date
EA200870224A1 (ru)	2009-02-27
JP5250427B2 (ja)	2013-07-31
WO2007088190A1 (en)	2007-08-09
AR059282A1 (es)	2008-03-19
JP2009525309A (ja)	2009-07-09
CA2640277A1 (en)	2007-08-09
EP2457897A1 (en)	2012-05-30
EP1979316A1 (en)	2008-10-15
CR10207A (es)	2008-09-22
MA30209B1 (fr)	2009-02-02
AU2007211484A1 (en)	2007-08-09
TW200808722A (en)	2008-02-16
JP2013082734A (ja)	2013-05-09
US20110201663A1 (en)	2011-08-18
BRPI0708024A2 (pt)	2011-05-17
US8252833B2 (en)	2012-08-28
EP1979316B1 (en)	2012-07-11
IL192934A0 (en)	2009-02-11
UY30121A1 (es)	2007-08-31
ES2390491T3 (es)	2012-11-13
KR20080097417A (ko)	2008-11-05
PE20070949A1 (es)	2007-11-22
SG169380A1 (en)	2011-03-30

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Publication	Publication Date	Title
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