CR10219A - Piperidinoil pirrolidinas agonistas del receptor de melanocrotina tipo 4. - Google Patents

Piperidinoil pirrolidinas agonistas del receptor de melanocrotina tipo 4.

Info

Publication number
CR10219A
CR10219A CR10219A CR10219A CR10219A CR 10219 A CR10219 A CR 10219A CR 10219 A CR10219 A CR 10219A CR 10219 A CR10219 A CR 10219A CR 10219 A CR10219 A CR 10219A
Authority
CR
Costa Rica
Prior art keywords
pirrolidines
piprolidinoil
melanocrotine
agonistas
receptor type
Prior art date
Application number
CR10219A
Other languages
English (en)
Inventor
Mark David Andrews
Alan Daniel Brown
Mark Ian Lansdell
Nicholas William Summerhill
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of CR10219A publication Critical patent/CR10219A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a una clase de agonistas de MCR4 de melanocortina de fórmula general (I) en la que las variables y sustituyentes son como se definen en este documento y especialmente a compuestos agonistas de MCR4 selectiva, a su uso en medicina, particularmente en el tratamiento de disfunción sexual y obesidad, a productos intermedios útiles en su síntesis y a composiciones que los contienen.
CR10219A 2006-02-23 2008-08-19 Piperidinoil pirrolidinas agonistas del receptor de melanocrotina tipo 4. CR10219A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77629506P 2006-02-23 2006-02-23
US88784007P 2007-02-02 2007-02-02

Publications (1)

Publication Number Publication Date
CR10219A true CR10219A (es) 2008-09-23

Family

ID=38169450

Family Applications (1)

Application Number Title Priority Date Filing Date
CR10219A CR10219A (es) 2006-02-23 2008-08-19 Piperidinoil pirrolidinas agonistas del receptor de melanocrotina tipo 4.

Country Status (21)

Country Link
US (1) US8138188B2 (es)
EP (1) EP1989196B1 (es)
KR (1) KR101036981B1 (es)
AP (1) AP2008004602A0 (es)
AU (1) AU2007219236B2 (es)
BR (1) BRPI0708264A2 (es)
CA (1) CA2642922C (es)
CR (1) CR10219A (es)
DK (1) DK1989196T3 (es)
EA (1) EA200801738A1 (es)
EC (1) ECSP088688A (es)
ES (1) ES2402581T3 (es)
IL (1) IL193279A (es)
MA (1) MA30228B1 (es)
ME (1) MEP6808A (es)
MX (1) MX2008010899A (es)
NO (1) NO20083480L (es)
RS (1) RS20080371A (es)
SG (1) SG185849A1 (es)
TN (1) TNSN08337A1 (es)
WO (1) WO2007096763A2 (es)

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US8588773B2 (en) 2008-08-04 2013-11-19 Qualcomm Incorporated System and method for cell search and selection in a wireless communication system
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PT2722045T (pt) 2009-11-18 2016-10-18 Helsinn Healthcare Sa Composições para o tratamento de náuseas e vómitos mediadas centralmente
EP2722045B1 (en) 2009-11-18 2016-07-06 Helsinn Healthcare SA Compositions for treating centrally mediated nausea and vomiting
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
WO2012120052A1 (de) 2011-03-08 2012-09-13 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
PL3333165T3 (pl) 2015-08-04 2019-12-31 Astellas Pharma Inc. Pochodne piperazyny
US20210393621A1 (en) 2018-10-26 2021-12-23 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
MX2022015706A (es) 2020-06-09 2023-01-24 Pfizer Antagonistas del receptor de melanocortina 4 y usos de estos.
ES3039638T3 (en) 2021-12-06 2025-10-23 Pfizer Melanocortin 4 receptor antagonists and uses thereof
WO2025228902A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Heterocyclic acids as sting antagonists and the use thereof as medicament
WO2025228900A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Arylamide substituted indazoles and the use thereof as medicament
WO2025228899A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Further heterocyclic compounds as sting antagonists and the use thereof as medicament
US20250333398A1 (en) 2024-04-30 2025-10-30 Boehringer Ingelheim International Gmbh Monoaryl and hetaryl substituted indazoles and benzimidazoles as sting antagonists and the use thereof as medicament
WO2025228895A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Hetaryl substituted indazoles and benzimidazoles as sting antagonists and the use thereof as medicament
WO2025228889A1 (en) 2024-04-30 2025-11-06 Boehringer Ingelheim International Gmbh Monoarylic heterocyclic compounds as sting antagonists and the use thereof as medicament
US12605394B2 (en) 2024-07-25 2026-04-21 Visionary Assets, Llc Compositions containing cannabinoid nanoparticles

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Also Published As

Publication number Publication date
AU2007219236B2 (en) 2012-06-21
KR101036981B1 (ko) 2011-05-25
ES2402581T3 (es) 2013-05-06
AU2007219236A1 (en) 2007-08-30
US20090036459A1 (en) 2009-02-05
DK1989196T3 (da) 2013-04-15
IL193279A (en) 2012-12-31
MEP6808A (xx) 2010-02-10
BRPI0708264A2 (pt) 2011-05-24
EP1989196A2 (en) 2008-11-12
SG185849A1 (en) 2012-12-28
EP1989196B1 (en) 2013-02-13
HK1126489A1 (en) 2009-09-04
IL193279A0 (en) 2009-02-11
CA2642922A1 (en) 2007-08-30
ECSP088688A (es) 2008-10-31
WO2007096763A2 (en) 2007-08-30
EA200801738A1 (ru) 2008-12-30
MX2008010899A (es) 2008-11-27
CA2642922C (en) 2011-08-02
TNSN08337A1 (fr) 2009-12-29
MA30228B1 (fr) 2009-02-02
WO2007096763A3 (en) 2007-10-18
US8138188B2 (en) 2012-03-20
KR20080095918A (ko) 2008-10-29
NO20083480L (no) 2008-09-10
RS20080371A (sr) 2009-07-15
AP2008004602A0 (en) 2008-10-31

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