CR10263A - Induccion y estabilizacion de actividad enzimatica en microorganismos - Google Patents

Induccion y estabilizacion de actividad enzimatica en microorganismos

Info

Publication number
CR10263A
CR10263A CR10263A CR10263A CR10263A CR 10263 A CR10263 A CR 10263A CR 10263 A CR10263 A CR 10263A CR 10263 A CR10263 A CR 10263A CR 10263 A CR10263 A CR 10263A
Authority
CR
Costa Rica
Prior art keywords
activity
microorganisms
stabilization
induction
enzymatic activity
Prior art date
Application number
CR10263A
Other languages
English (en)
Inventor
George E Pierce
Gene Drago
Sangeeta Ganguly
Original Assignee
Georgia State Univ Res Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Georgia State Univ Res Foundation filed Critical Georgia State Univ Res Foundation
Publication of CR10263A publication Critical patent/CR10263A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención trata sobre métodos para inducir una actividad deseada en enzimas o en los microorganismos capaces de producir las enzimas. Adicionalmente la invención trata sobre métodos para estabilizar la actividad en los microorganismos. En las incorporaciones específicas, la invención provee métodos para inducir y estabilizar la actividad de la nitrilo hidratasa, la actividad de la amidasa y la actividad de la asparaginasa. Adicionalmente la invención provee composiciones que inlcuyen enzimas o microorganismos que poseen una actividad inducida y/o estabilizada.
CR10263A 2006-01-30 2008-08-29 Induccion y estabilizacion de actividad enzimatica en microorganismos CR10263A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76330106P 2006-01-30 2006-01-30
US82257006P 2006-08-16 2006-08-16

Publications (1)

Publication Number Publication Date
CR10263A true CR10263A (es) 2009-01-19

Family

ID=38198134

Family Applications (1)

Application Number Title Priority Date Filing Date
CR10263A CR10263A (es) 2006-01-30 2008-08-29 Induccion y estabilizacion de actividad enzimatica en microorganismos

Country Status (12)

Country Link
US (4) US7531344B2 (es)
EP (2) EP3399022A1 (es)
CN (1) CN102634504B (es)
AU (1) AU2007211036B2 (es)
BR (1) BRPI0708008A2 (es)
CA (2) CA2676926C (es)
CR (1) CR10263A (es)
MX (1) MX283562B (es)
NZ (3) NZ599631A (es)
PH (1) PH12012500300A1 (es)
WO (1) WO2007090122A2 (es)
ZA (1) ZA200807391B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7531344B2 (en) 2006-01-30 2009-05-12 Georgia State University Research Foundation, Inc. Induction and stabilization of enzymatic activity in microorganisms
US7943549B2 (en) * 2007-04-02 2011-05-17 Georgia State University Research Foundation, Inc. Biological-based catalyst to delay plant development processes
AU2010282976A1 (en) 2009-08-13 2012-04-05 Geosynfuels, Llc Apparatus and process for fermentation of biomass hydrolysate
WO2011020082A1 (en) * 2009-08-13 2011-02-17 Geosynfuels, Llc Process for producing high value products from biomass
US20130035232A1 (en) * 2010-01-25 2013-02-07 Georgia State University Research Foundation, Inc. Induction and stabilization of enzymatic activity in microorganisms
US9334507B2 (en) 2012-06-15 2016-05-10 Microvi Biotech, Inc. Bioprocesses for making butanol
US9255281B2 (en) 2012-06-15 2016-02-09 Microvi Biotech Inc. Bioconversion processes using water-insoluble liquids
US9752164B2 (en) 2012-06-15 2017-09-05 Microvi Biotech, Inc. Enhanced efficiency ethanol and sugar conversion processes
CN104619652B (zh) 2012-06-15 2017-06-13 微视生物技术有限公司 生物催化剂组合物和使用的方法
US9993005B2 (en) 2013-03-14 2018-06-12 Georgia State University Research Foundation, Inc. Preventing or delaying chill injury response in plants
MX361278B (es) 2013-03-14 2018-12-03 Univ Georgia State Res Found Inhibición o reducción del crecimiento de hongos.
CA2951900A1 (en) 2014-06-10 2015-12-17 Georgia State University And Research Foundation, Inc. Inhibiting or reducing fungal infections
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11504418B2 (en) 2016-11-04 2022-11-22 Crowpierce Technologies, Llc Endotoxin free asparaginase
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
JP6670786B2 (ja) * 2017-03-23 2020-03-25 キオクシア株式会社 ダイシング方法及びレーザー加工装置
EA032896B1 (ru) * 2017-06-15 2019-07-31 Акционерное Общество "Биоамид" Способ культивирования штамма rhodococcus rhodochrous m33
CN109652474A (zh) * 2018-12-26 2019-04-19 安徽巨成精细化工有限公司 生物催化丙烯腈水合反应的方法、产腈菌株的灭活方法
CN119285110A (zh) * 2024-06-28 2025-01-10 北京衍微科技有限公司 一种含红球菌的生物修复菌剂及其应用

Family Cites Families (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2245585B1 (es) 1973-09-19 1976-05-14 Anvar
FR2294999A1 (fr) * 1974-12-18 1976-07-16 Anvar Procede de preparation d'amides par hydrolyse biologique
JPS54129190A (en) 1978-03-29 1979-10-06 Nitto Chem Ind Co Ltd Microbial preparation of acrylamide or methacrylamide
SU829484A1 (ru) 1979-02-06 1981-05-15 Специальное Конструкторско-Техноло-Гическое Бюро C Опытным Производствомминистерства Торговли Белорусскойсср Упаковка дл свежих сельскохоз й-СТВЕННыХ пРОдуКТОВ
DE3037009A1 (de) 1979-10-04 1981-04-23 Nitto Chemical Industry Co., Ltd., Tokyo Verfahren zur herstellung von acrylamid aus acrylnitril unter verwendung von mikroorganismen
JPS5991879A (ja) 1982-11-16 1984-05-26 Hideaki Yamada シユ−ドモナス属細菌の培養法
JPS62257386A (ja) 1986-05-02 1987-11-09 Nitto Chem Ind Co Ltd ニトリル水和活性の保持方法
JPS62259586A (ja) 1986-05-02 1987-11-11 Nitto Chem Ind Co Ltd ニトリル水和活性の保持方法
DD274631A5 (de) 1987-09-18 1989-12-27 Kk Verfahren zur biologischen herstellung von amiden
CZ280901B6 (cs) 1988-10-06 1996-05-15 Hideaki Yamada Způsob kultivace bakterií
US6207881B1 (en) 1990-09-10 2001-03-27 The United States Of America As Represented By The Department Of Agriculture Control of fruit ripening through genetic control of ACC synthase synthesis
AU9113791A (en) 1990-12-26 1992-08-17 Monsanto Company Control of fruit ripening and senescence in plants
JPH0530983A (ja) 1991-08-05 1993-02-09 Mitsubishi Kasei Corp アミド類の製造法
JPH0530982A (ja) 1991-08-05 1993-02-09 Mitsubishi Kasei Corp アミド類の製造法
JPH05236977A (ja) 1991-09-12 1993-09-17 Mitsubishi Kasei Corp アミド類の製造法
US5545815A (en) 1991-10-08 1996-08-13 The Regents Of The University Of California Control of fruit ripening in plants
HU9201218D0 (en) 1992-04-10 1992-06-29 Eotvos Lorand Tudomanyegyetem Process for the entering of non-auxotrophic bacteries -belonging to the azotobacteraceae family - into the intercellular spaces of plant tissues, for their cultivation in vitro, with the aim to create new nitrogenfixing plant-bacterium symbiosis
JPH0856684A (ja) 1994-08-16 1996-03-05 Mitsui Toatsu Chem Inc 微生物によるアミド化合物の製造法
JPH08154691A (ja) 1994-12-02 1996-06-18 Sumitomo Chem Co Ltd アミド化合物の製造方法
IT1275697B1 (it) * 1994-12-20 1997-10-17 Olmo Giancarlo Dell Metodo per stampare direttamente su carta microincisioni di ologrammi,chinogrammi,reticoli di diffrazione o microincisioni
JPH08187092A (ja) 1995-01-10 1996-07-23 Sumitomo Chem Co Ltd 好熱性微生物が有するニトリル化合物をアミド化合物に変換させる水和活性を向上させる方法
JP2711647B2 (ja) 1995-01-20 1998-02-10 信一 沢田 青果物等の鮮度保持方法
AU7514896A (en) 1995-10-06 1997-04-28 E.I. Du Pont De Nemours And Company Nucleic acid fragments encoding stereospecific nitrile hydratase and amidase enzymes and recombinant microorganisms expressing those enzymes useful for the production of chiral amides and acides
CN1260363C (zh) 1996-02-14 2006-06-21 三井化学株式会社 由腈化合物生产酰胺的方法
US7966767B2 (en) 2001-10-31 2011-06-28 Global Biosciences, Inc. Enhanced plant growth using alkane biostimulation
US6060265A (en) * 1996-12-18 2000-05-09 Cytec Technology Corporation Methods for the detoxification of nitrile and/or amide compounds
US5863750A (en) * 1996-12-18 1999-01-26 Cytec Tech Corp Methods for the detoxification of nitrile and/or amide compounds
ATE265226T1 (de) 1997-06-09 2004-05-15 Los Angeles Childrens Hospital Verwendung von wolinella succinogenes asparaginase zur behandlung von asparagin- abhängiger krankheiten
TR200002113T2 (tr) 1997-11-10 2001-01-22 Wisconsin Alumni Research Foundation Lisofosfatidiletanolamin (18:1) ve lisofosfatidilinositolün yaşlanmayı geçiktirmek ve meyve olgunlaşmasını artırmak için kullanımı.
US5945324A (en) * 1997-12-23 1999-08-31 Eli Lilly And Company Multiple drug resistance gene ATRC of aspergillus nidulans
EP1073714A1 (en) 1998-02-06 2001-02-07 Danmarks Jordbrugsforskning Ethylene oxidizing microorganism and use thereof
JP3408737B2 (ja) 1998-03-16 2003-05-19 三井化学株式会社 ニトリルヒドラターゼの活性化に関与するタンパク質及びそれをコードする遺伝子
US6153415A (en) * 1998-04-29 2000-11-28 Board Of Trustees Operating Michigan State University Method for producing amide compounds using a nitrile hydratase from a thermophilic bacillus
EP1077252A1 (en) 1998-05-06 2001-02-21 Keijiro Nakamura Microbial culture liquors containing microorganisms differing in characteristics and living in symbiosis and metabolites thereof, carriers and adsorbents containing the active components of the culture liquors and utilization of the same
DK173418B1 (da) 1998-06-29 2000-10-02 Bentle Products Ag Bånd med spiringselementer og pakning heraf, samt fremgangsmåde og anlæg til deres fremstilling
DK173999B1 (da) 1998-06-29 2002-04-02 Bentle Products Ag Blanding af et bæremiddel og tilsætningsstoffer til brug i spiringselementer indeholdende frø eller lignende vækstegnede plantedele samt fremgangsmåde til fremstilling af blandingen
JP2000050866A (ja) 1998-08-06 2000-02-22 Rikagaku Kenkyusho ニトリルヒドラターゼの生産方法
US6194193B1 (en) 1998-12-11 2001-02-27 David J. Drahos Nutrient plant formulation with microbial strains
US6524998B1 (en) 1999-03-01 2003-02-25 Auburn University Biological compositions and methods for enhancing plant growth and health and producing disease-suppressive plants
US6551804B2 (en) 1999-07-12 2003-04-22 E. I. Du Pont De Nemours And Company Process for preparing 4-cyanopentanoic acid
US6677149B2 (en) * 1999-07-12 2004-01-13 E. I. Du Pont De Nemours And Company Method for stabilizing nitrilase activity and preserving microbial cells with carbamate salts
EP1283256B1 (en) * 2000-03-21 2007-07-25 Mitsubishi Rayon Co., Ltd. Method of culturing microorganisms
AR025644A1 (es) 2000-09-12 2002-12-04 Sintesis Quimica S A I C Una composicion inoculante en base acuosa para semillas, y un metodo para conservar la composicion.
US6949362B2 (en) 2000-12-12 2005-09-27 E. I. Du Pont De Nemours And Company Rhodococcus cloning and expression vectors
DE10102555B4 (de) 2001-01-19 2014-04-10 Suet Saat- Und Erntetechnik Gmbh Saatgut mit einer Stickstoff-Dünger enthaltenden Umhüllung
US6735905B1 (en) * 2001-03-14 2004-05-18 Chi Overhead Doors, Inc. Ratcheting winding cone
AU2002307321B2 (en) 2001-04-11 2006-08-17 Cornell Research Foundation, Inc. Nucleic acid molecules relating to papaya ripening
ITMI20011826A1 (it) * 2001-08-30 2003-03-02 Istituto Biochimico Italiano Microorganismo dotato di attivita' nitrile-idratasica/amidasica enantioselettiva e regioselettiva
US20050000154A1 (en) 2001-10-31 2005-01-06 Global Biosciences, Inc. Apparatus and methods for enhanced plant and lawn growth using alkane injection
WO2003041491A2 (en) 2001-11-13 2003-05-22 Agricore United Doubled haploid production and genetic transformation
US20030093946A1 (en) 2001-11-20 2003-05-22 Gutierrez Pavez Victor Hugo Species-specific biomass eclosor (EBES)
GEP20063920B (en) 2001-12-20 2006-09-11 Bristol Myers Squibb Co Alpha-(n-sulphonamido) acetamide derivatives as beta-amyloid inhibitors
US20040072694A1 (en) 2002-02-25 2004-04-15 Jacobson Richard Martin Method to inhibit ethylene responses in plants
AT412157B (de) 2002-07-15 2004-10-25 Dsm Fine Chem Austria Gmbh Screeningmethode zum nachweis von amidase- und nitrilhydrataseaktivitäten und deren verwendung
US20040225116A1 (en) * 2003-05-08 2004-11-11 Payne Mark S. Nucleic acid fragments encoding nitrile hydratase and amidase enzymes from comamonas testosteroni 5-MGAM-4D and recombinant organisms expressing those enzymes useful for the production of amides and acids
JP4389064B2 (ja) 2003-05-28 2009-12-24 三井化学株式会社 ニトリルヒドラターゼ活性を維持または向上させる方法
US7504557B2 (en) 2003-06-23 2009-03-17 The Regents Of The University Of California Genes which produce staygreen characteristics in maize and their uses
US8569037B2 (en) 2003-10-29 2013-10-29 Kureha Corporation Fungus having activity of controlling disease of gramineous plant, controlling agent using the same, method of controlling and biological material
KR101106943B1 (ko) * 2003-12-02 2012-01-19 시바 스페셜티 케미칼스 워터 트리트먼츠 리미티드 로도코커스 로도크로스 ncimb 41164의 균주 및 니트릴하이드라타제의 생산자로서의 이의 용도
US20050227356A1 (en) 2004-04-07 2005-10-13 Lessard Philip A Novel compositions and methods for genetic manipulation of Rhodococcus bacteria
US8592343B2 (en) 2005-09-09 2013-11-26 Embrapa And Universidade Federal Rural Do Rio De Janeiro Polymeric compositions containing rhizobium and/or plant growth-promoting rhizobacteria inoculant, use thereof and seeds treated with the compositions
US20070090122A1 (en) 2005-10-26 2007-04-26 Caplugs Llp Textured vinyl pull cap
US7531344B2 (en) * 2006-01-30 2009-05-12 Georgia State University Research Foundation, Inc. Induction and stabilization of enzymatic activity in microorganisms
US7943549B2 (en) 2007-04-02 2011-05-17 Georgia State University Research Foundation, Inc. Biological-based catalyst to delay plant development processes
JP5236977B2 (ja) 2008-03-28 2013-07-17 三井造船株式会社 ガスハイドレート生成プラントにおける脱水装置
JP5030983B2 (ja) 2009-02-10 2012-09-19 株式会社日立製作所 列車の停止検知システム並びに列車の移動速度及び位置検出システム
US20130035232A1 (en) 2010-01-25 2013-02-07 Georgia State University Research Foundation, Inc. Induction and stabilization of enzymatic activity in microorganisms

Also Published As

Publication number Publication date
US9605241B2 (en) 2017-03-28
US20070184528A1 (en) 2007-08-09
EP3399022A1 (en) 2018-11-07
MX283562B (es) 2011-02-01
PH12012500300A1 (en) 2007-08-09
CN102634504A (zh) 2012-08-15
CA2976962A1 (en) 2007-08-09
AU2007211036B2 (en) 2012-03-01
CA2676926A1 (en) 2007-08-09
EP1991659A2 (en) 2008-11-19
EP1991659B1 (en) 2018-04-04
AU2007211036A1 (en) 2007-08-09
US20070184543A1 (en) 2007-08-09
NZ599631A (en) 2013-08-30
US20090203103A1 (en) 2009-08-13
US20130122565A1 (en) 2013-05-16
HK1173747A1 (en) 2013-05-24
US7531343B2 (en) 2009-05-12
NZ612756A (en) 2015-01-30
BRPI0708008A2 (pt) 2011-05-17
US8323942B2 (en) 2012-12-04
US7531344B2 (en) 2009-05-12
ZA200807391B (en) 2009-12-30
WO2007090122A2 (en) 2007-08-09
NZ570825A (en) 2012-05-25
WO2007090122A3 (en) 2008-01-17
MX2008009784A (es) 2008-10-21
CN102634504B (zh) 2015-05-13
CA2676926C (en) 2017-10-10

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