CR7769A - 4-(indazol-3-il) fenoles sustituidos como ligandos del receptor de estrogeno (re) y su uso en el tratamiento de enfermedades inflamatorias - Google Patents

4-(indazol-3-il) fenoles sustituidos como ligandos del receptor de estrogeno (re) y su uso en el tratamiento de enfermedades inflamatorias

Info

Publication number
CR7769A
CR7769A CR7769A CR7769A CR7769A CR 7769 A CR7769 A CR 7769A CR 7769 A CR7769 A CR 7769A CR 7769 A CR7769 A CR 7769A CR 7769 A CR7769 A CR 7769A
Authority
CR
Costa Rica
Prior art keywords
treatment
legands
strogen
indazol
receiver
Prior art date
Application number
CR7769A
Other languages
English (en)
Inventor
John Steffan Robert
Martin Matelan Edward
Anthony Ashwell Mark
Ronald Solvibile William
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of CR7769A publication Critical patent/CR7769A/es

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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
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  • Engineering & Computer Science (AREA)
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  • Diabetes (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)

Abstract

La invencion proporciona un compuesto de las formulas I o II que tienen la estructura en donde R1, R2,R3,R4, R5, R6,R7,R8,R9 y R10 son como definieron en la memoria descriptiva o una de sus sales farmaceuticamente aceptables que son utiles para el tratamiento del componente inflamatorio de enfermedades y son particularmente utiles para tratar arteriosclerosis, infarto de miocardio, insuficiencia cardiaca congestiva, enfermedad de intestino inflamado, artritis, diabetes de tipo II y enfermedades autoinmunes tales como esclerosis multiple y artritis reumatoidea.
CR7769A 2002-09-25 2005-03-28 4-(indazol-3-il) fenoles sustituidos como ligandos del receptor de estrogeno (re) y su uso en el tratamiento de enfermedades inflamatorias CR7769A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41393102P 2002-09-25 2002-09-25

Publications (1)

Publication Number Publication Date
CR7769A true CR7769A (es) 2005-08-12

Family

ID=32069719

Family Applications (1)

Application Number Title Priority Date Filing Date
CR7769A CR7769A (es) 2002-09-25 2005-03-28 4-(indazol-3-il) fenoles sustituidos como ligandos del receptor de estrogeno (re) y su uso en el tratamiento de enfermedades inflamatorias

Country Status (21)

Country Link
US (2) US7241791B2 (es)
EP (1) EP1542976B1 (es)
JP (1) JP4459813B2 (es)
KR (1) KR20050053702A (es)
CN (2) CN1321984C (es)
AR (1) AR041378A1 (es)
AT (1) ATE422202T1 (es)
AU (1) AU2003276940A1 (es)
BR (1) BR0314475A (es)
CA (1) CA2499736A1 (es)
CR (1) CR7769A (es)
DE (1) DE60326077D1 (es)
DK (1) DK1542976T3 (es)
EC (1) ECSP055704A (es)
ES (1) ES2319519T3 (es)
MX (1) MXPA05003275A (es)
NO (1) NO20051942L (es)
RU (1) RU2005109387A (es)
TW (1) TW200409759A (es)
WO (1) WO2004031159A1 (es)
ZA (1) ZA200502462B (es)

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