CR9540A - Formas solidas cristalinas de tigeciclina y metodos para preparar las mismas - Google Patents

Formas solidas cristalinas de tigeciclina y metodos para preparar las mismas

Info

Publication number
CR9540A
CR9540A CR9540A CR9540A CR9540A CR 9540 A CR9540 A CR 9540A CR 9540 A CR9540 A CR 9540A CR 9540 A CR9540 A CR 9540A CR 9540 A CR9540 A CR 9540A
Authority
CR
Costa Rica
Prior art keywords
forms
solid
tigecicline
crystaline
prepare
Prior art date
Application number
CR9540A
Other languages
English (en)
Inventor
Krishnan Lalitha
S Deshmukh Subodh
Hadfield Anthony
W Huang James
Sherry Ku Mannching
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37026996&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR9540(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of CR9540A publication Critical patent/CR9540A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • C07C231/24—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

Se describen en la presente las formas solidas cristalinas de tigeciclina, Forma I, Forma II, Forma III, Forma IV, Forma V, composiciones que comprenden estas formas solidas cristalinas, y procesos para preparar estas formas solidas cristalinas.
CR9540A 2005-05-27 2007-11-22 Formas solidas cristalinas de tigeciclina y metodos para preparar las mismas CR9540A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68495505P 2005-05-27 2005-05-27

Publications (1)

Publication Number Publication Date
CR9540A true CR9540A (es) 2008-02-21

Family

ID=37026996

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9540A CR9540A (es) 2005-05-27 2007-11-22 Formas solidas cristalinas de tigeciclina y metodos para preparar las mismas

Country Status (27)

Country Link
US (1) US8372995B2 (es)
EP (1) EP1890996B1 (es)
JP (2) JP2008545717A (es)
KR (1) KR20080016890A (es)
CN (1) CN101248038B (es)
AR (1) AR057649A1 (es)
AU (1) AU2006251954A1 (es)
BR (1) BRPI0610653A2 (es)
CA (1) CA2609875C (es)
CL (1) CL2006001266A1 (es)
CR (1) CR9540A (es)
DK (1) DK1890996T3 (es)
EC (1) ECSP078055A (es)
ES (1) ES2415518T3 (es)
GT (1) GT200600227A (es)
IL (1) IL187359A (es)
MX (1) MX2007014735A (es)
NO (1) NO20076005L (es)
PE (1) PE20070024A1 (es)
PL (1) PL1890996T3 (es)
PT (1) PT1890996E (es)
RU (1) RU2478612C2 (es)
SI (1) SI1890996T1 (es)
SV (1) SV2008002542A (es)
TW (1) TWI421232B (es)
WO (1) WO2006128150A2 (es)
ZA (1) ZA200710151B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2007713A2 (en) * 2006-04-17 2008-12-31 Teva Pharmaceutical Industries Ltd Isolation of tetracycline derivatives
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
ES2622356T3 (es) 2006-04-24 2017-07-06 Teva Pharmaceutical Industries, Ltd. Formas cristalinas de tigeciclina y procesos para su preparación
EP2086926A2 (en) 2006-11-29 2009-08-12 Teva Pharmaceutical Industries Ltd. Crystalline forms of tigecycline and processes for preparation thereof
EP2084126A1 (en) * 2006-11-30 2009-08-05 Teva Pharmaceutical Industries Ltd. Processes for preparation of 9-haloacetamidominocyclines
PT103661B (pt) * 2007-02-23 2010-09-07 Hovione Farmaciencia S A Processo de preparação de minociclina base cristalina
EP2114865A1 (en) * 2007-03-01 2009-11-11 Teva Pharmaceutical Industries Ltd. Processes for purification of tigecycline
AT13157U1 (de) * 2007-04-24 2013-07-15 Teva Pharma Tigecyclin, kristalline Formen und Herstellungsverfahren dafür
EP2178827A1 (en) 2007-06-21 2010-04-28 Sandoz AG Crystalline solid forms
WO2009062964A1 (en) * 2007-11-14 2009-05-22 Sandoz Ag Novel solvate
WO2009062963A1 (en) * 2007-11-14 2009-05-22 Sandoz Ag Crystalline forms of tigecycline hydrochloride
WO2009070799A1 (en) * 2007-11-29 2009-06-04 Teva Pharmaceutical Industries Ltd. Processes for preparation of crystalline tigecycline form ii
WO2009092680A2 (en) * 2008-01-23 2009-07-30 Sandoz Ag Antibiotic compounds
ITMI20080807A1 (it) 2008-05-05 2009-11-06 Antibioticos Spa Procedimento per la preparazione di tigeciclina in forma amorfa
TW202332671A (zh) * 2008-05-19 2023-08-16 美商Ｐｒｔｋ Ｓｐｖ２公司 四環素化合物之甲苯磺酸鹽及同素異形體
CA2746585C (en) 2008-12-18 2017-08-29 Sandoz Ag Crystalline form c of tigecycline dihydrochloride and methods for its preparation
PT104350A (pt) 2009-01-23 2010-07-23 Hovione Farmaci Ncia S A Processo de isolamento de tigeciclina
CN102746183B (zh) * 2011-04-20 2014-12-17 胡梨芳 替加环素结晶水合物及其制备方法和用途
CN102295576A (zh) * 2011-06-29 2011-12-28 赵军旭 替加环素的晶型及其制备方法
CN102898325B (zh) * 2011-07-29 2015-07-08 江苏奥赛康药业股份有限公司 替加环素晶体及其制备方法
CN102924322B (zh) * 2012-11-05 2014-09-17 赵军旭 一种替加环素的新晶型及其制备方法
CN103833590A (zh) * 2012-11-26 2014-06-04 石药集团中奇制药技术（石家庄）有限公司 替加环素晶型及其制备方法
RU2764723C2 (ru) * 2016-06-22 2022-01-19 Кбп Байосайенсиз Ко., Лтд. Кристаллические формы 9-аминометил-замещенного соединения тетрациклина и способ их получения
CA3196954A1 (en) 2020-11-03 2022-05-12 Josep Bassaganya-Riera Crystalline forms of piperazine-1,4-diylbis((6-(1h-benzoi[d]imidazo-2-yl)pyridin-2yl)methanone) as lancl2 modulators
CN116917009A (zh) 2021-02-19 2023-10-20 美国迈胜医疗系统有限公司 用于粒子治疗系统的机架

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2168254T3 (es) 1991-10-04 2002-06-16 American Cyanamid Co Nuevas 7-sustituidas-9-(amino sustituido)-6-desmetil-6-desoxitetraciclinas.
SG47520A1 (en) 1992-08-13 1998-04-17 American Cyanamid Co New method for the production of 9-amino-6-demethyl-6-deoxytetracycline
US5420272A (en) 1992-08-13 1995-05-30 American Cyanamid Company 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
US5284963A (en) 1992-08-13 1994-02-08 American Cyanamid Company Method of producing 7-(substituted)-9-[(substituted glycyl)-amidol]-6-demethyl-6-deoxytetra-cyclines
US5328902A (en) 1992-08-13 1994-07-12 American Cyanamid Co. 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
US5675030A (en) * 1994-11-16 1997-10-07 American Cyanamid Company Method for selective extracting a 7-(hydrogen or substituted amino)-9- (substituted glycyl) amido!-6-demethyl-6-deoxytetracycline compound
NZ519984A (en) * 2000-01-07 2004-03-26 Transform Pharmaceuticals Inc High-throughput formation, identification, and analysis of diverse solid-forms
CN102512429A (zh) * 2005-03-14 2012-06-27 惠氏公司 替加环素组合物及制备方法
AR057033A1 (es) * 2005-05-27 2007-11-14 Wyeth Corp Tigeciclina y metodos para preparar 9-nitrominociclina
AR057034A1 (es) * 2005-05-27 2007-11-14 Wyeth Corp Metodos para purificar tigeciclina
AR057032A1 (es) * 2005-05-27 2007-11-14 Wyeth Corp Tigeciclina y metodos de preparacion
AR057324A1 (es) * 2005-05-27 2007-11-28 Wyeth Corp Tigeciclina y metodos para preparar 9-aminominociclina

Also Published As

Publication number Publication date
AR057649A1 (es) 2007-12-12
EP1890996A2 (en) 2008-02-27
NO20076005L (no) 2008-02-22
JP2008545717A (ja) 2008-12-18
PL1890996T3 (pl) 2013-08-30
WO2006128150A3 (en) 2007-03-08
SV2008002542A (es) 2008-02-22
ES2415518T3 (es) 2013-07-25
TWI421232B (zh) 2014-01-01
HK1113786A1 (en) 2008-10-17
RU2007143160A (ru) 2009-07-10
CN101248038B (zh) 2014-03-05
IL187359A0 (en) 2008-04-13
GT200600227A (es) 2007-01-12
IL187359A (en) 2013-04-30
AU2006251954A1 (en) 2006-11-30
EP1890996B1 (en) 2013-04-24
DK1890996T3 (da) 2013-05-13
TW200720232A (en) 2007-06-01
RU2478612C2 (ru) 2013-04-10
MX2007014735A (es) 2008-02-15
CA2609875A1 (en) 2006-11-30
BRPI0610653A2 (pt) 2010-07-13
CL2006001266A1 (es) 2008-05-16
CN101248038A (zh) 2008-08-20
PE20070024A1 (es) 2007-02-06
KR20080016890A (ko) 2008-02-22
US20070123497A1 (en) 2007-05-31
JP2013100354A (ja) 2013-05-23
CA2609875C (en) 2014-01-07
ECSP078055A (es) 2008-01-23
WO2006128150A2 (en) 2006-11-30
ZA200710151B (en) 2010-05-26
SI1890996T1 (sl) 2013-06-28
PT1890996E (pt) 2013-06-24
US8372995B2 (en) 2013-02-12

Similar Documents

Publication Publication Date Title
CR9540A (es) Formas solidas cristalinas de tigeciclina y metodos para preparar las mismas
HN2006011218A (es) Composiciones de tigeciclina y métodos de preparación
ECSP078042A (es) Tigeciclina y métodos para preparar 9-nitrominociclina
ECSP078056A (es) Tigeciclina y métodos para preparar 9-aminominociclina
NI200700302A (es) Métodos para purificar tigeciclina
CR9541A (es) Tigeciclina y metodos de preparacion
CR9569A (es) Modificaciones cristalinas de la piraclostrobina
AR061311A1 (es) Procesos para preparar clorhidrato de cinacalcet y formas polimorficas del mismo
MX355428B (es) Formas cristalinas del acido [ (4-hidroxi-1-metil-7-fenoxi-isoquin olin-3-carbonil) -amino] -acetico inhibidor de prolil hidroxilasa.
DOP2010000351A (es) Activadores de glucoquinasa
CU23614B7 (es) Forma cristalina beta del clorhidrato de la ivabradina, su procedimiento de preparación y las composiciones farmacéuticas que la contienen
UY32704A (es) Compuestos de 2,3-dihidro-1h-indeno
GT200600346A (es) Nueva fórmula cristalina v de la agomelatina, un proceso para su preparación y composiciones farmacéuticas que la contienen
CR10388A (es) Composiciones antibioticas de libracion modificada y procesos para la produccion de las mismas.
CO6551754A2 (es) 7-[3.5-dihidroxi-2-(3-hidrixi-5-fenil-pent-1-enil)- ciclopentil] -n-etil-hept-5-enamida(bimatoprost) en forma cristalina ii, mètodos para la preparaciòn y mètodo para su uso
BRPI0606132A2 (pt) formas cristalinas de docetaxel e processos para seu preparo
ECSP077306A (es) Derivados de alquiliden-tetrahidronaftaleno, procedimiento para su preparación y su uso como antiinflamatorios
CR7876A (es) Forma cristalina alfa del ranelato de estroncio, procedimiento para su preparacion y composiciones farmaceuticas que la contienen
UY29434A1 (es) Derivados de tetrahidronaftalina, procedimientos para su preparación y su uso como inhibidores de la inflamacinn
ECSP109874A (es) Nuevos compuestos 892
UY29481A1 (es) Derivados de tetrahidronaftalina, procedimientos para su preparación y su uso como antiinflamatorios.
CR9988A (es) Procedimiento para la preparación del inhibidor del ciclo celular-779 cristalino y purificado
BRPI0605917A2 (pt) intermediário cristalino de rosuvastatina
UY29482A1 (es) Derivados de tetrahidronaftalina, procedimientos para su preparación y su uso como antiinflamatorios.
DOP2005000275A (es) Aminoalcoholes triciclicos, procedimeintos para su preparacion y su uso como inhibidores de inflamacion

Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)