CU24164B1 - Inhibidores sustituidos de acetil-coa carboxilasa - Google Patents

Inhibidores sustituidos de acetil-coa carboxilasa

Info

Publication number
CU24164B1
CU24164B1 CU20130126A CU20130126A CU24164B1 CU 24164 B1 CU24164 B1 CU 24164B1 CU 20130126 A CU20130126 A CU 20130126A CU 20130126 A CU20130126 A CU 20130126A CU 24164 B1 CU24164 B1 CU 24164B1
Authority
CU
Cuba
Prior art keywords
carboxilasa
acetil
coa
inhibitors
replaced
Prior art date
Application number
CU20130126A
Other languages
English (en)
Other versions
CU20130126A7 (es
Inventor
Robert Lee Dow
David Andrew Griffith
Jr James Alfred Southers
David James Edmonds
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CU20130126A7 publication Critical patent/CU20130126A7/es
Publication of CU24164B1 publication Critical patent/CU24164B1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Photographic Processing Devices Using Wet Methods (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CU20130126A 2011-04-22 2012-04-09 Inhibidores sustituidos de acetil-coa carboxilasa CU24164B1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161478240P 2011-04-22 2011-04-22
PCT/IB2012/051732 WO2012143813A1 (en) 2011-04-22 2012-04-09 Pyrazolospiroketone derivatives for use as acetyl - coa carboxylase inhibitors

Publications (2)

Publication Number Publication Date
CU20130126A7 CU20130126A7 (es) 2014-01-29
CU24164B1 true CU24164B1 (es) 2016-03-31

Family

ID=46025823

Family Applications (1)

Application Number Title Priority Date Filing Date
CU20130126A CU24164B1 (es) 2011-04-22 2012-04-09 Inhibidores sustituidos de acetil-coa carboxilasa

Country Status (43)

Country Link
US (4) US8802688B2 (es)
EP (1) EP2699576B1 (es)
JP (1) JP5657174B2 (es)
KR (1) KR101567659B1 (es)
CN (2) CN106117205B (es)
AP (1) AP3499A (es)
AR (1) AR086198A1 (es)
AU (1) AU2012245996B2 (es)
CA (1) CA2831380C (es)
CL (1) CL2013002794A1 (es)
CO (1) CO6801757A2 (es)
CR (1) CR20130464A (es)
CU (1) CU24164B1 (es)
CY (1) CY1117122T1 (es)
DK (1) DK2699576T3 (es)
DO (1) DOP2013000243A (es)
EA (1) EA022375B1 (es)
EC (1) ECSP13013038A (es)
ES (1) ES2561452T3 (es)
GE (1) GEP20166474B (es)
GT (1) GT201300258A (es)
HR (1) HRP20151397T1 (es)
HU (1) HUE028602T2 (es)
IL (1) IL228949A (es)
MA (1) MA35061B1 (es)
ME (1) ME02312B (es)
MX (1) MX348860B (es)
MY (1) MY162167A (es)
NI (1) NI201300111A (es)
NZ (1) NZ616156A (es)
PE (1) PE20141187A1 (es)
PH (1) PH12013501941A1 (es)
PL (1) PL2699576T3 (es)
PT (1) PT2699576E (es)
PY (1) PY1218709A (es)
RS (1) RS54526B1 (es)
SG (1) SG194142A1 (es)
SI (1) SI2699576T1 (es)
TN (1) TN2013000393A1 (es)
TW (1) TWI464171B (es)
UA (1) UA107753C2 (es)
UY (1) UY34027A (es)
WO (1) WO2012143813A1 (es)

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JPWO2015056782A1 (ja) 2013-10-17 2017-03-09 塩野義製薬株式会社 新規アルキレン誘導体
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CN106999451B (zh) 2014-09-17 2021-04-02 里科瑞尔姆Ip控股有限责任公司 双环化合物
KR102676056B1 (ko) * 2015-12-31 2024-06-19 베이징 구쉔 라이프 헬스 테크놀로지 컴퍼니 리미티드 비알코올성 지방간 질환의 치료 또는 예방용 의약의 제조에서의 트리아세틸-3-하이드록시페닐아데노신의 용도
CN106580986B (zh) * 2016-11-28 2017-09-15 王保亮 一种治疗少弱精子症的药物组合物
KR20200018440A (ko) 2017-05-15 2020-02-19 리커리엄 아이피 홀딩스, 엘엘씨 진통제 화합물
IL313710A (en) 2017-11-21 2024-08-01 Pfizer Crystalline 2-amino-2-(hydroxymethyl)propane-1,3-diol salt of 4-(4-(1-isopropyl-7-oxo-1,4,6,7-tetrahydrospiro[indazole-5,4'-piperidine]-1'-carbonyl)-6-methoxypyridin-2-yl)benzoic acid
CN118791407A (zh) 2018-05-22 2024-10-18 奥索生物公司 亚磺酰基氨基苯甲酰胺以及磺酰基氨基苯甲酰胺衍生物
CN111574530B (zh) * 2020-04-21 2022-07-26 徐州医科大学 一种acc抑制剂及其医药用途
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Also Published As

Publication number Publication date
PY1218709A (es) 2016-01-01
MX2013012313A (es) 2014-01-31
CL2013002794A1 (es) 2013-12-27
CN106117205A (zh) 2016-11-16
PT2699576E (pt) 2016-03-09
SG194142A1 (en) 2013-11-29
KR20140015511A (ko) 2014-02-06
PE20141187A1 (es) 2014-09-18
WO2012143813A1 (en) 2012-10-26
MY162167A (en) 2017-05-31
DOP2013000243A (es) 2013-12-31
AP2013007129A0 (en) 2013-09-30
CR20130464A (es) 2013-10-16
US20150336958A1 (en) 2015-11-26
TN2013000393A1 (fr) 2015-01-20
PH12013501941A1 (en) 2021-06-23
US20120270893A1 (en) 2012-10-25
GT201300258A (es) 2015-06-02
RS54526B1 (sr) 2016-06-30
UY34027A (es) 2013-04-05
IL228949A0 (en) 2013-12-31
NZ616156A (en) 2014-08-29
CN103492388A (zh) 2014-01-01
EA201391288A1 (ru) 2014-04-30
CA2831380A1 (en) 2012-10-26
US20150112068A1 (en) 2015-04-23
ME02312B (me) 2016-06-20
CA2831380C (en) 2016-04-05
US8802688B2 (en) 2014-08-12
CU20130126A7 (es) 2014-01-29
PL2699576T3 (pl) 2016-05-31
TWI464171B (zh) 2014-12-11
AR086198A1 (es) 2013-11-27
CO6801757A2 (es) 2013-11-29
GEP20166474B (en) 2016-05-10
TW201305162A (zh) 2013-02-01
AU2012245996A1 (en) 2013-10-03
IL228949A (en) 2016-11-30
AP3499A (en) 2015-12-31
JP2014515755A (ja) 2014-07-03
ES2561452T3 (es) 2016-02-26
AU2012245996B2 (en) 2016-09-01
MA35061B1 (fr) 2014-04-03
MX348860B (es) 2017-06-30
DK2699576T3 (en) 2016-02-15
HRP20151397T1 (hr) 2016-01-15
NI201300111A (es) 2014-02-12
US20140323730A1 (en) 2014-10-30
ECSP13013038A (es) 2014-01-31
EA022375B1 (ru) 2015-12-30
EP2699576A1 (en) 2014-02-26
KR101567659B1 (ko) 2015-11-09
HUE028602T2 (hu) 2016-12-28
JP5657174B2 (ja) 2015-01-21
SI2699576T1 (sl) 2016-02-29
EP2699576B1 (en) 2015-12-09
CN106117205B (zh) 2018-09-21
UA107753C2 (xx) 2015-02-10
CY1117122T1 (el) 2017-04-05

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