ECSP13013038A - Inhibidores sustituidos de acetil-coa carboxilasa - Google Patents

Inhibidores sustituidos de acetil-coa carboxilasa

Info

Publication number
ECSP13013038A
ECSP13013038A ECSP13013038A ECSP13013038A EC SP13013038 A ECSP13013038 A EC SP13013038A EC SP13013038 A ECSP13013038 A EC SP13013038A EC SP13013038 A ECSP13013038 A EC SP13013038A
Authority
EC
Ecuador
Prior art keywords
coa
carboxilasa
acetil
inhibitors
replaced
Prior art date
Application number
Other languages
English (en)
Inventor
Robert Lee Dow
Jr James Alfred Southers
David Andrew Griffith
David James Edmonds
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ECSP13013038A publication Critical patent/ECSP13013038A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Photographic Processing Devices Using Wet Methods (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

La invención proporciona un compuesto de Fórmula (I)Fórmula (I)o una sal del mismo aceptable desde el punto de vista farmacéutico; donde G esR1, R2 y R3 son como se describe en la presente; composiciones farmacéuticas del mismo; y el uso del mismo en el tratamiento de enfermedades, afecciones o trastornos modulados por la inhibición de una enzima(s) acetil-CoA carboxilasa en un animal.
ECSP13013038 2011-04-22 2013-11-22 Inhibidores sustituidos de acetil-coa carboxilasa ECSP13013038A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161478240P 2011-04-22 2011-04-22

Publications (1)

Publication Number Publication Date
ECSP13013038A true ECSP13013038A (es) 2014-01-31

Family

ID=46025823

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP13013038 ECSP13013038A (es) 2011-04-22 2013-11-22 Inhibidores sustituidos de acetil-coa carboxilasa

Country Status (43)

Country Link
US (4) US8802688B2 (es)
EP (1) EP2699576B1 (es)
JP (1) JP5657174B2 (es)
KR (1) KR101567659B1 (es)
CN (2) CN106117205B (es)
AP (1) AP3499A (es)
AR (1) AR086198A1 (es)
AU (1) AU2012245996B2 (es)
CA (1) CA2831380C (es)
CL (1) CL2013002794A1 (es)
CO (1) CO6801757A2 (es)
CR (1) CR20130464A (es)
CU (1) CU24164B1 (es)
CY (1) CY1117122T1 (es)
DK (1) DK2699576T3 (es)
DO (1) DOP2013000243A (es)
EA (1) EA022375B1 (es)
EC (1) ECSP13013038A (es)
ES (1) ES2561452T3 (es)
GE (1) GEP20166474B (es)
GT (1) GT201300258A (es)
HR (1) HRP20151397T1 (es)
HU (1) HUE028602T2 (es)
IL (1) IL228949A (es)
MA (1) MA35061B1 (es)
ME (1) ME02312B (es)
MX (1) MX348860B (es)
MY (1) MY162167A (es)
NI (1) NI201300111A (es)
NZ (1) NZ616156A (es)
PE (1) PE20141187A1 (es)
PH (1) PH12013501941A1 (es)
PL (1) PL2699576T3 (es)
PT (1) PT2699576E (es)
PY (1) PY1218709A (es)
RS (1) RS54526B1 (es)
SG (1) SG194142A1 (es)
SI (1) SI2699576T1 (es)
TN (1) TN2013000393A1 (es)
TW (1) TWI464171B (es)
UA (1) UA107753C2 (es)
UY (1) UY34027A (es)
WO (1) WO2012143813A1 (es)

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CN120457124A (zh) * 2022-12-30 2025-08-08 苏州浦合医药科技有限公司 Prmt5-mta抑制剂
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Also Published As

Publication number Publication date
AR086198A1 (es) 2013-11-27
EA201391288A1 (ru) 2014-04-30
PL2699576T3 (pl) 2016-05-31
TW201305162A (zh) 2013-02-01
PT2699576E (pt) 2016-03-09
CN103492388A (zh) 2014-01-01
DOP2013000243A (es) 2013-12-31
CN106117205A (zh) 2016-11-16
CA2831380C (en) 2016-04-05
MX2013012313A (es) 2014-01-31
CO6801757A2 (es) 2013-11-29
TN2013000393A1 (fr) 2015-01-20
US8802688B2 (en) 2014-08-12
CL2013002794A1 (es) 2013-12-27
CU20130126A7 (es) 2014-01-29
AP2013007129A0 (en) 2013-09-30
AU2012245996A1 (en) 2013-10-03
KR101567659B1 (ko) 2015-11-09
US20120270893A1 (en) 2012-10-25
NZ616156A (en) 2014-08-29
MX348860B (es) 2017-06-30
SG194142A1 (en) 2013-11-29
US20150112068A1 (en) 2015-04-23
HUE028602T2 (hu) 2016-12-28
EP2699576A1 (en) 2014-02-26
EA022375B1 (ru) 2015-12-30
CY1117122T1 (el) 2017-04-05
AP3499A (en) 2015-12-31
PE20141187A1 (es) 2014-09-18
PH12013501941A1 (en) 2021-06-23
CU24164B1 (es) 2016-03-31
UA107753C2 (xx) 2015-02-10
PY1218709A (es) 2016-01-01
US20150336958A1 (en) 2015-11-26
AU2012245996B2 (en) 2016-09-01
DK2699576T3 (en) 2016-02-15
UY34027A (es) 2013-04-05
JP5657174B2 (ja) 2015-01-21
ES2561452T3 (es) 2016-02-26
HRP20151397T1 (hr) 2016-01-15
MA35061B1 (fr) 2014-04-03
MY162167A (en) 2017-05-31
SI2699576T1 (sl) 2016-02-29
GEP20166474B (en) 2016-05-10
NI201300111A (es) 2014-02-12
US20140323730A1 (en) 2014-10-30
GT201300258A (es) 2015-06-02
WO2012143813A1 (en) 2012-10-26
IL228949A0 (en) 2013-12-31
EP2699576B1 (en) 2015-12-09
RS54526B1 (sr) 2016-06-30
KR20140015511A (ko) 2014-02-06
TWI464171B (zh) 2014-12-11
JP2014515755A (ja) 2014-07-03
CN106117205B (zh) 2018-09-21
ME02312B (me) 2016-06-20
CA2831380A1 (en) 2012-10-26
IL228949A (en) 2016-11-30
CR20130464A (es) 2013-10-16

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