CY2143B1 - Sustained release tablets containing bupropion - Google Patents

Sustained release tablets containing bupropion

Info

Publication number
CY2143B1
CY2143B1 CY9900040A CY9900040A CY2143B1 CY 2143 B1 CY2143 B1 CY 2143B1 CY 9900040 A CY9900040 A CY 9900040A CY 9900040 A CY9900040 A CY 9900040A CY 2143 B1 CY2143 B1 CY 2143B1
Authority
CY
Cyprus
Prior art keywords
sustained release
tablets containing
release tablets
hydrochloride
containing bupropion
Prior art date
Application number
CY9900040A
Other languages
English (en)
Inventor
Jennie Sue Galloway Ludwig
Joel Elmore Sutton Jr
William Leroy Bass Jr
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10720358&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2143(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of CY2143B1 publication Critical patent/CY2143B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CY9900040A 1992-08-14 1999-11-29 Sustained release tablets containing bupropion CY2143B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929217295A GB9217295D0 (en) 1992-08-14 1992-08-14 Controlled released tablets

Publications (1)

Publication Number Publication Date
CY2143B1 true CY2143B1 (en) 2002-06-21

Family

ID=10720358

Family Applications (1)

Application Number Title Priority Date Filing Date
CY9900040A CY2143B1 (en) 1992-08-14 1999-11-29 Sustained release tablets containing bupropion

Country Status (20)

Country Link
US (1) US5427798A (fr)
EP (1) EP0656775B1 (fr)
JP (1) JPH08500110A (fr)
KR (1) KR100294154B1 (fr)
AT (1) ATE161422T1 (fr)
AU (1) AU677595B2 (fr)
CA (1) CA2142320C (fr)
CY (1) CY2143B1 (fr)
DE (1) DE69316015T2 (fr)
ES (1) ES2111168T3 (fr)
GB (1) GB9217295D0 (fr)
GR (1) GR3025794T3 (fr)
IL (1) IL106693A (fr)
LU (1) LU90656I2 (fr)
MX (1) MX9304967A (fr)
NZ (1) NZ254947A (fr)
SG (1) SG43911A1 (fr)
TW (1) TW260607B (fr)
WO (1) WO1994004138A1 (fr)
ZA (1) ZA935942B (fr)

Families Citing this family (230)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9315856D0 (en) * 1993-07-30 1993-09-15 Wellcome Found Stabilized pharmaceutical
US5541231A (en) * 1993-07-30 1996-07-30 Glaxo Wellcome Inc. Stabilized Pharmaceutical
US5616344A (en) * 1994-06-14 1997-04-01 Fuisz Technologies Ltd. Apparatus and process for strengthening low density compression dosage units and product therefrom
DK1017392T3 (da) * 1997-09-25 2002-10-21 Bayer Ag Lægemiddel
US5968553A (en) * 1997-12-30 1999-10-19 American Home Products Corporation Pharmaceutical composition containing bupropion hydrochloride and an inorganic acid stabilizer
US6221917B1 (en) 1997-12-30 2001-04-24 American Home Products Corporation Pharmaceutical composition containing bupropion hydrochloride and a stabilizer
US7098206B2 (en) * 1998-01-21 2006-08-29 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6998400B2 (en) * 1998-01-22 2006-02-14 Smithkline Beecham Corporation Pharmaceutically active morpholinol
EP1051167A1 (fr) 1998-01-29 2000-11-15 Sepracor, Inc. Utilisations pharmaceutiques de (-)-bupropion optiquement pur
JP2002501888A (ja) * 1998-01-29 2002-01-22 セプラコア インコーポレーテッド 光学的に純粋な（−）−ビュープロピオンを用いて禁煙を支援するためのまたは疼痛や他の障害を治療するための方法および組成物
JP2002501891A (ja) 1998-01-29 2002-01-22 セプラコア インコーポレーテッド 光学的に純粋な（＋）−ビュープロピオンの医薬用途
EP1051166A1 (fr) * 1998-01-29 2000-11-15 Sepracor, Inc. Utilisations pharmaceutiques de (+)-bupropion optiquement pur
US6150420A (en) * 1998-06-01 2000-11-21 Theramax, Inc. Method for enhanced brain delivery of bupropion
US6153223A (en) * 1998-06-05 2000-11-28 Watson Pharmaceuticals, Inc. Stabilized pharmaceutical compositions
US6033686A (en) * 1998-10-30 2000-03-07 Pharma Pass Llc Controlled release tablet of bupropion hydrochloride
US6096341A (en) * 1998-10-30 2000-08-01 Pharma Pass Llc Delayed release tablet of bupropion hydrochloride
US6238697B1 (en) * 1998-12-21 2001-05-29 Pharmalogix, Inc. Methods and formulations for making bupropion hydrochloride tablets using direct compression
US6855820B2 (en) 1999-01-20 2005-02-15 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6734213B2 (en) 1999-01-20 2004-05-11 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6210716B1 (en) * 1999-02-26 2001-04-03 Andrx Pharmaceuticals, Inc. Controlled release bupropion formulation
US6589553B2 (en) * 2001-02-08 2003-07-08 Andrx Pharmaceuticals, Inc. Controlled release oral dosage form
US8545880B2 (en) * 1999-02-26 2013-10-01 Andrx Pharmaceuticals, Llc Controlled release oral dosage form
US6342496B1 (en) * 1999-03-01 2002-01-29 Sepracor Inc. Bupropion metabolites and methods of use
US6337328B1 (en) 1999-03-01 2002-01-08 Sepracor, Inc. Bupropion metabolites and methods of use
USD430285S (en) * 1999-04-16 2000-08-29 Merck & Co., Inc. Tablet
US6280763B1 (en) 1999-05-10 2001-08-28 Pierce Management, Llc Apparatus and method for transdermal delivery of bupropion
CA2389236A1 (fr) * 1999-11-02 2001-05-10 Depomed, Inc. Declenchement pharmacologique du mode par ingestion pour une administration amelioree de medicaments dans l'estomac
US6306436B1 (en) 2000-04-28 2001-10-23 Teva Pharmaceuticals Usa, Inc. Stabilized, acid-free formulation for sustained release of bupropion hydrochloride
CA2685214C (fr) * 2001-02-08 2013-01-22 Andrx Pharmaceuticals, Inc. Forme posologique orale a liberation regulee amelioree
ITMI20011457A1 (it) * 2001-07-09 2003-01-09 Valpharma Sa Composizione farmaceutica a rilascio modificato contenente bupropionehc1 come sostanza attiva
US20030044462A1 (en) * 2001-08-20 2003-03-06 Kali Laboratories, Inc. Sustained release tablets containing bupropion hydrochloride
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents
JP4545584B2 (ja) * 2002-05-17 2010-09-15 デューク ユニバーシティ 肥満を治療するための方法
US20050215552A1 (en) * 2002-05-17 2005-09-29 Gadde Kishore M Method for treating obesity
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
WO2004041244A2 (fr) * 2002-10-30 2004-05-21 Pharmacia Corporation Comprimes oraux a liberation etendue et procedes de fabrication et d'utilisation associes
US20040096497A1 (en) * 2002-11-19 2004-05-20 Ponder Garratt W. Methods of providing controlled-release pharmaceutical compositions and controlled-release pharmaceutical compositions
US6893660B2 (en) * 2002-11-21 2005-05-17 Andrx Pharmaceuticals, Inc. Stable pharmaceutical compositions without a stabilizer
RU2350327C2 (ru) * 2003-04-29 2009-03-27 Ориксиджен Серапьютикс, Инкорпорэйтд Составы, вызывающие потерю веса
DE102004032051A1 (de) * 2004-07-01 2006-01-19 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US8075872B2 (en) 2003-08-06 2011-12-13 Gruenenthal Gmbh Abuse-proofed dosage form
DE10336400A1 (de) * 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
US20070048228A1 (en) * 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
RS51934B (sr) * 2003-08-08 2012-02-29 Biovail Laboratories International Srl. Tableta bupropion hidrohlorida sa modifikovanim otpuštanjem
US7713959B2 (en) 2004-01-13 2010-05-11 Duke University Compositions of an anticonvulsant and mirtazapine to prevent weight gain
US7429580B2 (en) 2004-01-13 2008-09-30 Orexigen Therapeutics, Inc. Compositions of an anticonvulsant and an antipsychotic drug and methods of using the same for affecting weight loss
US20060160750A1 (en) * 2004-01-13 2006-07-20 Krishnan K R R Compositions of an anticonvulsant and an antipsychotic drug and methods of using the same for affecting weight loss
US20060100205A1 (en) * 2004-04-21 2006-05-11 Eckard Weber Compositions for affecting weight loss
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
USD515202S1 (en) 2004-07-19 2006-02-14 Merck & Co., Inc Tablet
US8586085B2 (en) 2004-11-08 2013-11-19 Biokey, Inc. Methods and formulations for making pharmaceutical compositions containing bupropion
US20060099262A1 (en) * 2004-11-08 2006-05-11 Biokey, Inc. Methods and formulations for making controlled release oral dosage form
GB0425445D0 (en) * 2004-11-18 2004-12-22 Smithkline Beecham Corp Novel compositions
KR100670798B1 (ko) 2004-12-17 2007-01-17 한국전자통신연구원 데이터베이스 캐시 시스템
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US7884136B2 (en) 2005-06-27 2011-02-08 Biovail Laboratories International S.R.L. Modified-release formulations of a bupropion salt
EA200801080A1 (ru) * 2005-10-14 2009-02-27 Х. Лундбекк А/С Стабильные фармацевтические лекарственные формы, содержащие эсциталопрам и бупропион
CA2625835A1 (fr) * 2005-10-14 2007-05-10 Forest Laboratories, Inc. Procedes de traitement de troubles du systeme nerveux central avec une combinaison de faible dose d'escitaloprame et de bupropion
EP1951212A2 (fr) 2005-11-22 2008-08-06 Orexigen Therapeutics, Inc. Compositions et procedes d augmentation de la sensibilite a l insuline
AR057946A1 (es) * 2005-11-28 2007-12-26 Orexigen Therapeutics Inc Formulacion de zonisamida de liberacion sostenidda
CA2638734A1 (fr) * 2006-02-27 2007-09-07 The Board Of Trustees Of The Leland Stanford Junior University Inhibiteurs de la reponse aux proteines non depliees et procedes d'utilisation
EP1996118A4 (fr) 2006-03-07 2013-03-06 Osteoscreen Ip Llc RENFORCEMENT DE L'OS ET DU CARTILAGE PAR UN INHIBITEUR DE LA HMG Co-A RÉDUCTASE
US8916195B2 (en) 2006-06-05 2014-12-23 Orexigen Therapeutics, Inc. Sustained release formulation of naltrexone
KR20090029725A (ko) 2006-06-13 2009-03-23 더 보드 오브 트러스티즈 오프 더 리랜드 스탠포드 쥬니어 유니버시티 시스테인 프로테아제의 에폭시드 저해물질
US8703191B2 (en) * 2006-07-25 2014-04-22 Intelgenx Corp. Controlled-release pharmaceutical tablets
US7674479B2 (en) * 2006-07-25 2010-03-09 Intelgenx Corp. Sustained-release bupropion and bupropion/mecamylamine tablets
US20100008987A1 (en) * 2006-08-21 2010-01-14 Pasula Basavaiah Chowdary Modified Release Pharmaceutical Composition of Bupropion Hydrochloride
TW201811315A (zh) 2006-11-09 2018-04-01 美商歐瑞根治療有限公司 層狀醫藥調配物
CA2668885C (fr) 2006-11-09 2016-08-02 Orexigen Therapeutics, Inc. Procedes d'administration de medications pour la perte de poids
DE102007011485A1 (de) 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
AR065989A1 (es) 2007-04-09 2009-07-15 Sepracor Inc Metodos y composiciones para el tratamiento de trastornos de la respiracion relacionados con el sueno
EP2167065A1 (fr) * 2007-06-18 2010-03-31 The General Hospital Corporation Thérapie par combinaison pour la dépression
US20090162434A1 (en) * 2007-12-21 2009-06-25 Disphar International Bv Mesalazine tablet
JP5774853B2 (ja) 2008-01-25 2015-09-09 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 医薬投薬形
US9339500B2 (en) 2008-03-04 2016-05-17 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms
MX2010012039A (es) 2008-05-09 2010-11-30 Gruenenthal Gmbh Proceso para la preparacion de una formulacion de polvo intermedia y una forma de dosificacion solida final bajo el uso de un paso de congelacion por rocio.
EP2303025A4 (fr) 2008-05-30 2012-07-04 Orexigen Therapeutics Inc Procédés pour traiter des pathologies des graisses viscérales
TW201039815A (en) 2009-04-13 2010-11-16 Resolvyx Pharmaceuticals Inc Compositions and methods for the treatment of inflammation
BR112012001547A2 (pt) * 2009-07-22 2016-03-08 Gruenenthal Gmbh forma de dosagem farmacêutica extrusada por fusão a quente
ES2428938T3 (es) 2009-07-22 2013-11-12 Grünenthal GmbH Forma de dosificación resistente a la manipulación y estabilizada frente a la oxidación
US20110136815A1 (en) * 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
EP3659604A1 (fr) 2010-01-11 2020-06-03 Nalpropion Pharmaceuticals, Inc. Méthodes d'amaigrissementu pour des patients souffrant d'une dépression sévère
CN102821757B (zh) 2010-02-03 2016-01-20 格吕伦塔尔有限公司 通过挤出机制备粉末状药物组合物
CN103179954A (zh) 2010-09-02 2013-06-26 格吕伦塔尔有限公司 包含阴离子聚合物的抗破碎剂型
CA2808219C (fr) 2010-09-02 2019-05-14 Gruenenthal Gmbh Forme pharmaceutique inviolable comportant un sel inorganique
BR112013008898A2 (pt) 2010-10-11 2016-06-28 Auckland Uniservices Limited benzamidas substituídas e seus usos
DK2632927T3 (en) 2010-10-26 2016-04-11 Mars Inc Boronates AS ARGINSASEINHIBITORER
PL2736497T3 (pl) 2011-07-29 2018-01-31 Gruenenthal Gmbh Tabletka odporna na ingerencję, zapewniająca natychmiastowe uwalnianie leku
CA2839123A1 (fr) 2011-07-29 2013-02-07 Grunenthal Gmbh Comprime anti-manipulation permettant une liberation immediate de medicament
HUE047642T2 (hu) 2011-11-21 2020-05-28 Calithera Biosciences Inc A glutamináz heterociklusos gátlói
MX356421B (es) 2012-02-28 2018-05-29 Gruenenthal Gmbh Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico.
JP2015516393A (ja) 2012-04-12 2015-06-11 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 置換ベンズアミドおよびその使用法
PL2838512T3 (pl) 2012-04-18 2018-12-31 Grünenthal GmbH Farmaceutyczna postać dawkowania odporna na niewłaściwe użycie i odporna na uderzeniowe uwalnianie dawki
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
PT3730132T (pt) 2012-06-06 2022-08-16 Nalpropion Pharmaceuticals Llc Composição para utilização num método de tratamento de excesso de peso e obesidade em doentes com alto risco cardiovascular
PT2920168T (pt) 2012-11-16 2021-10-18 Calithera Biosciences Inc Inibidores heterocíclicos de glutaminase
KR102279618B1 (ko) 2013-03-15 2021-07-20 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 활성 기반 프로브 화합물, 조성물, 및 사용 방법
MX371432B (es) 2013-05-29 2020-01-30 Gruenenthal Gmbh Forma de dosificacion resistente al uso indebido que contiene una o mas particulas.
WO2014191396A1 (fr) 2013-05-29 2014-12-04 Grünenthal GmbH Forme dosifiée inviolable à profil de libération bimodale
US10624862B2 (en) 2013-07-12 2020-04-21 Grünenthal GmbH Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
WO2015078891A1 (fr) 2013-11-26 2015-06-04 Farmaceutici Formenti S.P.A. Préparation de composition pharmaceutique en poudre par cryo-broyage
US20150320690A1 (en) 2014-05-12 2015-11-12 Grünenthal GmbH Tamper resistant immediate release capsule formulation comprising tapentadol
EP3148512A1 (fr) 2014-05-26 2017-04-05 Grünenthal GmbH Microparticules protégées contre une libération massive dans l'éthanol
EA036001B1 (ru) 2014-06-13 2020-09-11 Калитера Байосайенсиз, Инк. Комбинация эрлотиниба и ингибитора глутаминазы для лечения рака легких
CA2957225A1 (fr) 2014-08-07 2016-02-11 Calithera Biosciences, Inc. Formes cristallines d'inhibiteurs de glutaminase
EP3180332B1 (fr) 2014-08-13 2021-10-27 Eolas Therapeutics Inc. Difluoropyrrolidines en tant que modulateurs des récepteurs de l'orexine
WO2016070063A1 (fr) 2014-10-31 2016-05-06 The Regents Of The University Of California Compositions et méthodes de traitement d'un dysfonctionnement cognitif associé au vih
MX384444B (es) 2015-03-10 2025-03-14 Aurigene Discovery Tech Ltd Compuestos de 1,2,4-oxadiazol y tiadiazol como inmunomoduladores
BR112017021475A2 (pt) 2015-04-24 2018-07-10 Gruenenthal Gmbh forma de dosagem resistente à adulteração (tamper) com liberação imediata e resistência contra extração de solvente
AU2016281620B2 (en) 2015-06-23 2021-07-22 Calithera Biosciences, Inc. Compositions and methods for inhibiting arginase activity
KR102305932B1 (ko) * 2015-06-29 2021-09-28 플로로놀 인코퍼레이티드 갈조류의 고체 약제학적 조성물
AU2016319203A1 (en) 2015-09-10 2018-02-22 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations
GB2542881B (en) 2015-10-02 2020-01-01 Carr Andrew Crystal forms of ß-nicotinamide mononucleotide
JP6971239B2 (ja) 2015-10-05 2021-11-24 キャリセラ バイオサイエンシーズ， インコーポレイテッド グルタミナーゼ阻害剤とイムノオンコロジー薬剤との併用療法
SG11201802961PA (en) 2015-10-30 2018-05-30 Calithera Biosciences Inc Compositions and methods for inhibiting arginase activity
US10745435B2 (en) 2015-11-16 2020-08-18 Cerecor, Inc. Nucleic acid prodrugs
KR102738491B1 (ko) 2016-02-12 2024-12-03 아스트라제네카 아베 오렉신 수용체 조정제로서의 할로-치환된 피페리딘
JP7093955B2 (ja) 2016-04-14 2022-07-01 スピネカー バイオサイエンシーズ， インコーポレイテッド 治療剤の送達のためのケイ酸金属塩を含むポーラスシリコン物質
US20190134069A1 (en) 2016-04-22 2019-05-09 Viking Therapeutics, Inc. Use of thyroid beta-agonists
WO2017210565A1 (fr) 2016-06-03 2017-12-07 Prisident And Fellows Of Harvard College Composés antifongiques
WO2018039591A1 (fr) 2016-08-25 2018-03-01 California Institute Of Technology Traitement ascaroside de maladies auto-immunes et inflammatoires
WO2018039612A1 (fr) 2016-08-26 2018-03-01 The Regents Of The University Of California Compositions et méthodes favorisant la croissance des cheveux au moyen d'inhibiteurs de mpc1
US11583516B2 (en) 2016-09-07 2023-02-21 Trustees Of Tufts College Dash inhibitors, and uses related thereto
US10472364B2 (en) 2016-09-09 2019-11-12 Calithera Biosciences, Inc. Ectonucleotidase inhibitors and methods of use thereof
WO2018049094A1 (fr) 2016-09-09 2018-03-15 The Regents Of The University Of California Ligands du récepteur des oestrogènes, compositions et méthodes associées
EP3515449B1 (fr) 2016-09-26 2023-07-12 Dana-Farber Cancer Institute, Inc. Dérivés de quinoline en tant qi'inhibiteurs de la protéine chromobox (cbx) pour le traitement du cancer
CN110290835B (zh) 2016-09-28 2023-03-07 麦迪康制药公司 用于治疗眼科病况的组合物和方法
BR112019006160A2 (pt) 2016-09-28 2019-06-18 Medicon Pharmaceuticals Inc composições e métodos para o tratamento das condições oftálmicas
AU2017356942A1 (en) 2016-11-08 2019-05-23 Calithera Biosciences, Inc. Arginase inhibitor combination therapies
AU2017364077A1 (en) 2016-11-22 2019-06-20 Elektrofi, Inc. Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof
NZ754364A (en) 2016-12-22 2023-04-28 Calithera Biosciences Inc Compositions and methods for inhibiting arginase activity
CN110023740B (zh) 2016-12-23 2023-04-14 里兰斯坦福初级大学理事会 基于活性的探针化合物、组合物及其使用方法
JP2020511424A (ja) 2017-01-18 2020-04-16 ヴァンダービルト ユニバーシティーＶａｎｄｅｒｂｉｌｔ Ｕｎｉｖｅｒｓｉｔｙ 選択的ｂｍｐ阻害としての縮合複素環式化合物
WO2018154088A1 (fr) 2017-02-24 2018-08-30 Merck Patent Gmbh Dérivés de 1, 4, 6-trisubstitué-2-alkyl-1h-benzo[d]imidazole en tant qu'inhibiteurs de dihydroorotate oxygénase
AU2018242623B2 (en) 2017-03-31 2024-05-02 Aurigene Oncology Limited Compounds and compositions for treating hematological disorders
US10994025B2 (en) 2017-05-12 2021-05-04 Massachusetts Institute Of Technology Argonaute protein-double stranded RNA complexes and uses related thereto
WO2018223032A1 (fr) 2017-06-02 2018-12-06 Stealth Biotherapeutics Corp. Formes cristallines de sel de sbt-20
KR20250151619A (ko) 2017-06-30 2025-10-21 더 리전트 오브 더 유니버시티 오브 캘리포니아 모발 성장을 조절하기 위한 조성물 및 방법
US10526334B2 (en) 2017-07-19 2020-01-07 California Institute Of Technology Methods for preparing bis-tetrahydroisoquinoline-containing compounds
EP3658612A4 (fr) 2017-07-25 2021-06-02 Elektrofi, Inc. Formation de particules comprenant des agents
JP2020536855A (ja) 2017-09-26 2020-12-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア がんを治療するための組成物及び方法
AU2018346331B2 (en) 2017-10-04 2023-08-24 Dana-Farber Cancer Institute, Inc. Small molecule inhibition of transcription factor SALL4 and uses thereof
BR112020006669A2 (pt) 2017-10-11 2020-09-24 Aurigene Discovery Technologies Limited formas cristalinas de 1,2,4-oxadiazol 3-substituído
KR102697663B1 (ko) 2017-10-31 2024-08-21 쿠리스 인코퍼레이션 혈액학적 장애를 치료하기 위한 화합물 및 조성물
KR20200083503A (ko) 2017-11-03 2020-07-08 오리진 디스커버리 테크놀로지스 리미티드 Tim-3 경로와 pd-1 경로의 이중 저해제
EA202090749A1 (ru) 2017-11-06 2020-08-19 Ориджен Дискавери Текнолоджис Лимитед Способы совместной терапии для иммуномодуляции
RU2020124097A (ru) 2017-12-22 2022-01-24 Медиммьюн Лимитед НИЗКОМОЛЕКУЛЯРНЫЕ МОДУЛЯТОРЫ ДОМЕНА BTB Keap1
EP3749640B1 (fr) 2018-01-30 2025-07-16 The Regents of the University of California Inhibiteurs de la voie wnt/bêta-caténine
MX2020009443A (es) 2018-03-14 2021-01-08 Aurigene Discovery Tech Ltd Método de modulación de las vías de señalización de tigit y pd-1 mediante el uso de compuestos de 1,2,4-oxadiazol.
US10745400B2 (en) 2018-03-14 2020-08-18 Vanderbuilt University Inhibition of BMP signaling, compounds, compositions and uses thereof
US10933084B2 (en) 2018-04-12 2021-03-02 MatRx Therapeutics Corporation Compositions and methods for treating elastic fiber breakdown
US11155638B2 (en) 2018-05-08 2021-10-26 Rhode Island Hospital Anti-CHI3L1 antibodies for the detection and/or treatment of nonalcoholic fattly liver disease/nonalcoholic steatonhepatitis and subsequent complications
JP7402225B2 (ja) 2018-05-11 2023-12-20 ロード アイランド ホスピタル ヌクレオシド系逆転写酵素阻害剤を用いて関節障害を処置するための組成物および方法
WO2019226969A1 (fr) 2018-05-24 2019-11-28 Elektrofi, Inc. Particules comprenant un agent thérapeutique ou diagnostique et suspensions et leurs procédés d'utilisation
WO2020006489A1 (fr) 2018-06-29 2020-01-02 The Regents Of The University Of California Nouvelles pinces moléculaires contre des troubles neurologiques et des infections virales
CA3107750A1 (fr) 2018-07-27 2020-01-30 California Institute Of Technology Inhibiteurs de cdk et leurs utilisations
KR20210071974A (ko) 2018-09-05 2021-06-16 더 제너럴 하스피탈 코포레이션 사이토카인 방출 증후군을 치료하는 방법
EP3849310A4 (fr) 2018-09-12 2022-07-06 The Board of Regents of the University of Oklahoma Polythérapies anticancéreuses
EP3867223B1 (fr) 2018-10-17 2025-12-10 The Regents of the University of California Promédicaments d'alpha-cétoglutarate, d'alpha-cétobutyrate, d'alpha-cétoisovalérate, et d'alpha-cétoisohexanoate, et leurs utilisations
JP7504880B2 (ja) 2018-10-26 2024-06-24 ケロス セラピューティクス インコーポレイテッド Ａｌｋ２阻害剤の結晶形
CA3118026A1 (fr) 2018-10-31 2020-05-07 Intocell, Inc. Derives de benzodiazepine heterocycliques fusionnes et leurs utilisations
RS66416B1 (sr) 2019-01-18 2025-02-28 Astrazeneca Ab 6'-[[(1s,3s)-3-[[5-(difluorometoksi)-2-pirimidinil]amino]ciklopentil]amino][1(2h),3'-bipiridin]-2-on kao inhibitor pcsk9 i metode njegove primene
EP3911640A4 (fr) 2019-01-18 2022-10-26 Astrazeneca AB Inhibiteurs de pcsk9 et leurs procédés d'utilisation
EP3914604B1 (fr) 2019-01-25 2026-03-04 Brown University Compositions comprenant du censavudine ou de l'elvucitabine pour le traitement de l'inflammation et des troubles associés à l'âge
WO2020160323A2 (fr) 2019-01-31 2020-08-06 Elektrofi, Inc. Formation et morphologie de particules
AU2020234033B2 (en) 2019-03-14 2023-07-13 Astrazeneca Ab Lanabecestat for weight loss
EP3978076A4 (fr) 2019-06-03 2023-02-22 Irimajiri Therapeutics Inc. Composés d'amide cyclique pour le traitement de la rage et méthode associée
JP7781743B2 (ja) 2019-09-13 2025-12-08 エレクトロフィ，インコーポレイテッド 疾患の処置のための治療用生物学的作用剤の送達のための組成物及び方法
CA3157798A1 (fr) 2019-11-12 2021-05-20 Zhongli Gao Heteroarylaminosulfonamides a 6 chainons pour le traitement de maladies et d'etats medies par une activite cftr deficiente
WO2021113809A1 (fr) 2019-12-05 2021-06-10 Genzyme Corporation Arylamides et leurs procédés d'utilisation
WO2021113806A1 (fr) 2019-12-05 2021-06-10 Genzyme Corporation Arylamides et leurs procédés d'utilisation
CA3164800A1 (fr) 2019-12-16 2021-06-24 Unist(Ulsan National Institute Of Science And Technology) Compose destine a inhiber le facteur d'angiogenese et son utilisation
US20230113944A1 (en) 2020-01-10 2023-04-13 The Regents Of The University Of California Compositions and methods for the treatment of neurodegenerative diseases
US20230094393A1 (en) 2020-02-07 2023-03-30 Elektrofi, Inc. Peptide particles and methods of formation
US20230065628A1 (en) 2020-02-19 2023-03-02 Elektrofi, Inc. Droplet Formation and Particle Morphology
IL296196A (en) * 2020-03-05 2022-11-01 Abbvie Inc Methods of administering elagolix
US20230158028A1 (en) 2020-04-06 2023-05-25 The Regents Of The University Of California Compounds and methods for inducing ucp1 expression
CN115484934A (zh) 2020-04-17 2022-12-16 伊勒卓菲公司 通过连续液滴形成和脱水形成颗粒的方法
MX2022013657A (es) 2020-05-05 2023-02-01 Nuvalent Inc Quimioterápicos de éter macrocíclico heteroaromático.
EP4146205A4 (fr) 2020-05-05 2024-05-29 Nuvalent, Inc. Agents chimiothérapeutiques à base d'éther macrocyclique hétéroaromatique
WO2021263072A1 (fr) 2020-06-25 2021-12-30 Dana-Farber Cancer Institute, Inc. Méthodes de traitement d'une maladie
CN111830151B (zh) * 2020-07-01 2021-05-04 迪沙药业集团有限公司 盐酸安非他酮组合物质量控制用系统适用性对照品
US20230271918A1 (en) 2020-08-10 2023-08-31 Dana-Farber Cancer Institute, Inc. Substituted 3-amino-4-methylbenzenesulfonamides as small molecule inhibitors of ubiquitin-specific protease 28
CA3191163A1 (fr) 2020-08-10 2022-02-17 Dana-Farber Cancer Institute, Inc. Inhibiteurs a petites molecules pyrimidine-thieno-pyridine tricycliques fusionnees de la protease 28 specifique de l'ubiquitine
CA3191164A1 (fr) 2020-08-10 2022-02-17 Dana-Farber Cancer Institute, Inc. 1,2,4-oxadiazoles substitues utilises en tant qu'inhibiteurs de petites molecules de la protease 28 specifique de l'ubiquitine
CN116323571A (zh) 2020-10-23 2023-06-23 丹娜法伯癌症研究院 肌酸激酶（ck）的共价抑制剂以及其用于治疗和预防癌症的用途
WO2022133237A2 (fr) 2020-12-18 2022-06-23 Cornell University Méthodes de traitement de troubles neurodégénératifs et de cancers liés à stat3 au moyen de suppresseurs de fuite d'électrons
IL303813A (en) 2020-12-21 2023-08-01 Univ Cornell Peptide-linked drug delivery system
WO2022150574A1 (fr) 2021-01-08 2022-07-14 Cornell University Inhibiteurs de la lipoamide déshydrogénase de mycobacterium tuberculosis
US12037346B2 (en) 2021-04-13 2024-07-16 Nuvalent, Inc. Amino-substituted heteroaryls for treating cancers with EGFR mutations
PE20241330A1 (es) 2021-09-03 2024-06-26 Genzyme Corp Compuestos de indol y metodos de uso
WO2023034946A1 (fr) 2021-09-03 2023-03-09 Genzyme Corporation Composés indoles et leurs utilisations dans le traitement de la fibrose kystique
WO2023056431A1 (fr) 2021-10-01 2023-04-06 Nuvalent, Inc. Méthodes de traitement d'une tumeur solide à l'aide de composés éther macrocycliques hétéroaromatiques
CA3231813A1 (fr) 2021-10-01 2023-04-06 Sibao CHEN Formes solides, compositions pharmaceutiques et preparation de composes ether macrocycliques heteroaromatiques
WO2023187422A1 (fr) 2022-03-31 2023-10-05 Revolo Biotherapeutics Limited Compositions et leur utilisation dans des procédés pour traiter une inflammation intestinale
TW202400608A (zh) 2022-04-07 2024-01-01 美商努法倫特公司 雜芳族巨環醚化合物之固體形式、醫藥組合物及製備
CN119212705A (zh) 2022-04-07 2024-12-27 纽威伦特公司 使用(19r)-5-氯-3-乙基-16-氟-10,19-二甲基-20-氧杂-3,4,10,11,23-五氮杂戊环[19.3.1.02,6.08,12.013,18]二十五碳-1(24),2(6),4,8,11,13,15,17,21(25),22-癸烯-22-胺治疗实体肿瘤的方法
CA3248272A1 (fr) 2022-04-29 2023-11-02 Elektrofi, Inc. Suspensions injectables
CN119562822A (zh) 2022-05-16 2025-03-04 雷沃洛生物医疗有限公司 用于预防或治疗食物过敏的方法和组合物
WO2023250157A1 (fr) 2022-06-24 2023-12-28 Cornell University Inhibiteurs de mycobacterium tuberculosis lipoamide déshydrogénase
US12156914B2 (en) 2022-06-30 2024-12-03 Axsome Therapeutics, Inc. Pharmaceutical compositions comprising bupropion and cysteine
CN118785900A (zh) * 2022-06-30 2024-10-15 艾克萨姆治疗公司 包含安非他酮和半胱氨酸的药物组合物
JP2025525415A (ja) 2022-07-13 2025-08-05 アストラゼネカ・アクチエボラーグ Ｐｃｓｋ９阻害剤およびその使用方法
KR20250044905A (ko) 2022-08-04 2025-04-01 다이이치 고교 세이야쿠 가부시키가이샤 고리형 펩티드 유도체와 그 제조 방법 및 조성물
WO2024036098A1 (fr) 2022-08-12 2024-02-15 Nuvalent, Inc. Composés d'éther macrocycliques hétéroaromatiques
WO2024036097A1 (fr) 2022-08-12 2024-02-15 Nuvalent, Inc. Composés d'éther macrocycliques hétéroaromatiques et isotopologues de ceux-ci
EP4593814A1 (fr) 2022-09-26 2025-08-06 Rose Research Center, LLC Combinaison destinée à être utilisée dans un procédé de prévention de gain de poids
JPWO2024071371A1 (fr) 2022-09-30 2024-04-04
IL319591A (en) 2022-09-30 2025-05-01 Dks Co Ltd Cyclic peptide derivative composition for treating or preventing eye diseases
AU2023364043A1 (en) 2022-10-19 2025-04-10 Nuvalent, Inc. Heteroaromatic macrocyclic ether chemotherapeutic agents
CN120152726A (zh) 2022-11-04 2025-06-13 第一工业制药株式会社 用于处置或预防中枢神经系统损伤疾病的环状肽衍生物组合物
EP4613283A1 (fr) 2022-11-04 2025-09-10 DKS Co. Ltd. Composition de dérivé peptidique cyclique pour le traitement ou la prévention de la douleur neuropathique et/ou de la douleur inflammatoire
AU2024258768A1 (en) 2023-04-18 2025-12-04 Revolo Biotherapeutics Limited Methods and compositions for preventing or treating eosinophilic esophagitis
EP4705330A1 (fr) 2023-05-05 2026-03-11 The Board of Regents of the University of Oklahoma Variants d'adrénomédulline (am) et d'adrénomédulline 2/intermédine (am2/imd) et procédés d'utilisation
WO2025037259A1 (fr) 2023-08-15 2025-02-20 Revolo Biotherapeutics Limited Méthodes et compositions pour la prévention ou le traitement de l'asthme sévère
WO2025042868A1 (fr) 2023-08-23 2025-02-27 The Board Of Regents Of The University Of Oklahoma Combinaisons d'hétéroarotinoïdes et d'inhibiteurs glycolytiques destinées à être utilisées en tant que traitements du cancer
TW202525266A (zh) 2023-09-18 2025-07-01 美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 可電離類脂質組成物及其治療用途
WO2025072120A1 (fr) 2023-09-25 2025-04-03 Nuvalent, Inc. Composés d'éther macrocycliques hétéroaromatiques
WO2025072117A1 (fr) 2023-09-25 2025-04-03 Nuvalent, Inc. Composés d'éther macrocycliques hétéroaromatiques et isotopologues de ceux-ci
WO2025085360A1 (fr) 2023-10-16 2025-04-24 The Board Of Regents Of The University Of Oklahoma Hétéroarotinoïdes et/ou inhibiteurs de cdk4/6 pour le traitement des verrues, des dysplasies induites par le papillomavirus humain (vph), et du cancer chez des individus infectés par le vph
WO2025088586A1 (fr) 2023-10-27 2025-05-01 Brown University Compositions, systèmes et méthodes de traitement du cancer à l'aide de champs de traitement de tumeur avec des inhibiteurs de mif, mica et/ou micb
WO2025106670A1 (fr) 2023-11-14 2025-05-22 Flagship Pioneering Innovations Vii, Llc Compositions lipidoïdes ionisables et leurs utilisations thérapeutiques
WO2025212478A1 (fr) 2024-04-01 2025-10-09 Nuvalent, Inc. Méthodes de traitement d'une tumeur solide à l'aide de composés éther macrocycliques hétéroaromatiques
WO2025235872A1 (fr) 2024-05-10 2025-11-13 Schrödinger, Inc. Hétérocycles en tant qu'inhibiteurs d'egfr
WO2025235874A1 (fr) 2024-05-10 2025-11-13 Schrödinger, Inc. Hétérocycles utiliséés en tant qu'inhibiteurs d'egfr
US20250383333A1 (en) 2024-06-12 2025-12-18 Elektrofi, Inc. Determination of particulate contaminants in particles and compositions
WO2026050339A1 (fr) 2024-08-27 2026-03-05 Halozyme Hypercon, Inc. Procédés de préparation d'échantillons pour des tests analytiques

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759838A (fr) * 1969-12-04 1971-06-03 Wellcome Found Cetones a activite biologique
US3885046A (en) * 1969-12-04 1975-05-20 Burroughs Wellcome Co Meta chloro or fluoro substituted alpha-T-butylaminopropionphenones in the treatment of depression
CA948388A (en) * 1970-02-27 1974-06-04 Paul B. Hansen Pattern bonded continuous filament web
US4347257A (en) * 1979-10-09 1982-08-31 Burroughs Wellcome Co. Prolactin suppression in mammals
AU552261B2 (en) * 1980-01-21 1986-05-29 Wellcome Foundation Limited, The Use of propiophenone derivatives as adjuncts to benzo- diazepine tranquillisers
US4356165A (en) * 1980-04-14 1982-10-26 Burroughs Wellcome Co. Bupropion radioimmunoassay, and kit
US4347178A (en) * 1980-04-14 1982-08-31 Burroughs Wellcome Co. Compounds and methods of making
US4347176A (en) * 1980-04-14 1982-08-31 Burroughs Wellcome Co. Compounds and methods of making same
US4355179A (en) * 1980-04-14 1982-10-19 Burroughs Wellcome Co. Radioactive nuclide labeled propiophenone compounds
US4347177A (en) * 1980-04-14 1982-08-31 Burroughs Wellcome Co. Compounds and methods of making them
US4347382A (en) * 1980-04-15 1982-08-31 Burroughs Wellcome Co. 3H Labeled compounds
US4435449A (en) * 1981-05-14 1984-03-06 Burroughs Wellcome Co. Treatment of minimal brain dysfunction (MBD)
US4425363A (en) * 1981-05-14 1984-01-10 Burroughs Wellcome Co. Treatment of tardive dyskinesia in mammals
US4393078A (en) * 1982-03-15 1983-07-12 Burroughs Wellcome Co. Bupropion and ethanol
US4438138A (en) * 1982-12-06 1984-03-20 Burroughs Wellcome Co. Reduction of cholesterol with meta-chloro α-t-butylaminopropiophenone
GB8322007D0 (en) * 1983-08-16 1983-09-21 Wellcome Found Pharmaceutical delivery system
USRE33994E (en) * 1983-08-16 1992-07-14 Burroughs Wellcome Co. Pharmaceutical delivery system
US4507323A (en) * 1984-07-25 1985-03-26 Burroughs Wellcome Co. Treatment of psychosexual dysfunctions
US4769027A (en) * 1984-08-15 1988-09-06 Burroughs Wellcome Co. Delivery system
CA1239034A (fr) * 1984-08-17 1988-07-12 Kelly L. Smith Systeme de dispensation
WO1992019241A1 (fr) * 1991-05-07 1992-11-12 Dynagen, Inc. Systeme d'administration a liberation prolongee regulee utilise pour cesser de fumer

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DE69316015T2 (de) 1998-04-16
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GB9217295D0 (en) 1992-09-30
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SG43911A1 (en) 1997-11-14
MX9304967A (es) 1994-05-31
AU677595B2 (en) 1997-05-01
CA2142320A1 (fr) 1994-03-03
CA2142320C (fr) 2001-10-09
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IL106693A0 (en) 1993-12-08
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ES2111168T3 (es) 1998-03-01
KR100294154B1 (ko) 2001-09-17
EP0656775B1 (fr) 1997-12-29
ATE161422T1 (de) 1998-01-15
AU4725893A (en) 1994-03-15
WO1994004138A1 (fr) 1994-03-03
GR3025794T3 (en) 1998-03-31
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