CZ297440B6 - Lék pro prevenci nefrotoxicity nebo renální dysfunkce a farmaceutický prostredek - Google Patents

Lék pro prevenci nefrotoxicity nebo renální dysfunkce a farmaceutický prostredek Download PDF

Info

Publication number: CZ297440B6
Authority: CZ; Czechia
Prior art keywords: pps; cyclosporin; pharmaceutically acceptable; composition; pharmaceutical composition
Prior art date: 1997-10-09

Application number

CZ20001274A

Other languages

Czech (cs)

English (en)

Other versions

CZ20001274A3 (cs

Inventor

E. Striker@Gary

Striker@Lilliane

H. Kortright@Kenneth

Original Assignee

Baker Norton Pharmaceuticals, Inc.

The United States Of America, Represented By The Secretary Department Of Health & Human Services

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-10-09

Filing date

1998-10-09

Publication date

2006-12-13

1998-10-09 Application filed by Baker Norton Pharmaceuticals, Inc., The United States Of America, Represented By The Secretary Department Of Health & Human Services filed Critical Baker Norton Pharmaceuticals, Inc.

2001-12-12 Publication of CZ20001274A3 publication Critical patent/CZ20001274A3/cs

2006-12-13 Publication of CZ297440B6 publication Critical patent/CZ297440B6/cs

Links

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SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 1
231100000252 nontoxic Toxicity 0.000 description 1
230000003000 nontoxic effect Effects 0.000 description 1
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239000005426 pharmaceutical component Substances 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Urology & Nephrology (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Transplantation (AREA)
Toxicology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicinal Preparation (AREA)
Saccharide Compounds (AREA)
Cephalosporin Compounds (AREA)

CZ20001274A 1997-10-09 1998-10-09 Lék pro prevenci nefrotoxicity nebo renální dysfunkce a farmaceutický prostredek CZ297440B6 (cs)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US6294797P	1997-10-09	1997-10-09

Publications (2)

Publication Number	Publication Date
CZ20001274A3 CZ20001274A3 (cs)	2001-12-12
CZ297440B6 true CZ297440B6 (cs)	2006-12-13

Family

ID=22045901

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CZ20001274A CZ297440B6 (cs)	1997-10-09	1998-10-09	Lék pro prevenci nefrotoxicity nebo renální dysfunkce a farmaceutický prostredek

Country Status (23)

Country	Link
US (1)	US6187745B1 (fr)
EP (1)	EP1027053B1 (fr)
JP (1)	JP2001519392A (fr)
KR (1)	KR100515196B1 (fr)
CN (1)	CN1154492C (fr)
AT (1)	ATE269098T1 (fr)
AU (1)	AU748495B2 (fr)
BR (1)	BR9813860A (fr)
CA (1)	CA2304374A1 (fr)
CZ (1)	CZ297440B6 (fr)
DE (1)	DE69824619T2 (fr)
DK (1)	DK1027053T3 (fr)
ES (1)	ES2221714T3 (fr)
HU (1)	HUP0003904A3 (fr)
IL (1)	IL135235A0 (fr)
NO (1)	NO20001828L (fr)
NZ (1)	NZ503493A (fr)
PL (1)	PL191993B1 (fr)
PT (1)	PT1027053E (fr)
RU (1)	RU2191020C2 (fr)
SK (1)	SK285332B6 (fr)
UA (1)	UA65587C2 (fr)
WO (1)	WO1999018961A1 (fr)

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WO2001052867A1 (fr)	2000-01-19	2001-07-26	The United States Of America, Represented By The Secretary, Department Of Health And Human Services	Utilisation de polysulfate de pentosan pour le traitement de certains troubles de la prostate
US6613083B2 (en) *	2001-05-02	2003-09-02	Eckhard Alt	Stent device and method
EP1435910B9 (fr) *	2001-10-19	2010-02-03	Isotechnika Inc.	Nouveaux preconcentres en microemulsion d'analogues de cyclosporine
CN1646122A (zh) *	2002-04-16	2005-07-27	藤泽药品工业株式会社	用于预防和/或治疗慢性排斥的药物
EP2165711B1 (fr)	2004-05-27	2014-05-21	Baxter International Inc.	Procédé pour traiter des troubles du saignement à l'aide de polysaccharides sulfatés
JP5896742B2 (ja)	2008-08-22	2016-03-30	バクスター・ヘルスケヤー・ソシエテ・アノニムＢａｘｔｅｒＨｅａｌｔｈｃａｒｅＳＡ	出血性障害を処置するための方法
WO2011088267A1 (fr)	2010-01-14	2011-07-21	Baxter International Inc.	Méthodes et compositions pour traiter l'hémophilie
US8871741B2 (en) *	2010-01-15	2014-10-28	Icahn School Of Medicine At Mount Sinai	Inhibition of TNF-α induced activation of NFKB by pentosan polysulfate
CN102327282A (zh) *	2010-09-01	2012-01-25	吴洪	戊糖多聚硫酸酯用于制备治疗糖尿病肾病的药物中的用途
EP2734213B1 (fr)	2011-07-19	2018-06-06	Baxalta GmbH	Activateurs de résorption comme additifs pour améliorer la formulation orale de polysaccharides sulfatés non anticoagulants
WO2013052380A2 (fr) *	2011-10-05	2013-04-11	Allergan, Inc.	Composition pour améliorer la santé des ongles
CA2881785A1 (fr)	2012-08-14	2014-02-20	Baxter International Inc.	Procedes et systemes de criblage de compositions comprenant des polysaccharides sulfates non coagulants
WO2016099214A1 (fr) *	2014-12-18	2016-06-23	가톨릭대학교 산학협력단	Composition pour atténuer la néphrotoxicité résultant de l'administration de médicament immunosuppresseur, contenant de la metformine, et composition pour la prévention ou le traitement de maladies immunitaires la contenant
KR101760510B1 (ko)	2014-12-18	2017-07-21	가톨릭대학교 산학협력단	메트포민을 포함하는 면역억제제로 인한 신장 독성 완화용 조성물 및 이를 포함하는 면역질환 예방 또는 치료용 조성물
KR20180011840A (ko) *	2015-06-12	2018-02-02	비샬 자조디아 스와티	방광 출구 폐쇄 및/또는 하부 요로 증상의 치료에서 사용하기 위한 펜토산폴리설페이트나트륨을 포함하는 조성물

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DE3843241A1 (de) *	1988-12-22	1990-06-28	Skrezek Christian	Nephroprotektive infusionsloesung
EP0466315A3 (en)	1990-05-30	1992-07-01	Larrian Gillespie	Compositions containing xylan sulphates for affecting growth factor function and for inhibiting fibroblast proliferation
US5204329A (en)	1990-06-11	1993-04-20	Du Pont Merck Pharmaceutical Company	Treatment of organ transplantation rejection
GB9116836D0 (en) *	1991-08-05	1991-09-18	Sandoz Ltd	Organic compounds
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RU2027471C1 (ru) *	1992-04-14	1995-01-27	Северо-Кавказский горно-металлургический институт	Способ очистки суспензий и вибрационный фильтр-сгуститель для его осуществления
IT1277147B1 (it) *	1995-01-20	1997-11-04	Sigma Tau Ind Farmaceuti	Uso della carnitina e i suoi derivati per ridurre gli effetti tossici della ciclosporina-a e di altri farmaci immunosoppressivi.
JPH08208489A (ja) *	1995-02-03	1996-08-13	L T T Kenkyusho:Kk	腎不全治療剤
US5643892A (en) *	1995-06-07	1997-07-01	Baker Norton Pharmaceuticals, Inc.	Method of treating chronic progressive vascular diseases

1998
- 1998-09-10 UA UA2000041980A patent/UA65587C2/uk unknown
- 1998-10-01 US US09/168,974 patent/US6187745B1/en not_active Expired - Fee Related
- 1998-10-09 JP JP2000515596A patent/JP2001519392A/ja active Pending
- 1998-10-09 BR BR9813860-0A patent/BR9813860A/pt not_active Application Discontinuation
- 1998-10-09 AU AU97943/98A patent/AU748495B2/en not_active Ceased
- 1998-10-09 NZ NZ503493A patent/NZ503493A/en unknown
- 1998-10-09 PL PL339774A patent/PL191993B1/pl not_active IP Right Cessation
- 1998-10-09 HU HU0003904A patent/HUP0003904A3/hu unknown
- 1998-10-09 KR KR10-2000-7003305A patent/KR100515196B1/ko not_active Expired - Fee Related
- 1998-10-09 CZ CZ20001274A patent/CZ297440B6/cs not_active IP Right Cessation
- 1998-10-09 CN CNB988100363A patent/CN1154492C/zh not_active Expired - Fee Related
- 1998-10-09 IL IL13523598A patent/IL135235A0/xx not_active IP Right Cessation
- 1998-10-09 CA CA002304374A patent/CA2304374A1/fr not_active Abandoned
- 1998-10-09 ES ES98952186T patent/ES2221714T3/es not_active Expired - Lifetime
- 1998-10-09 RU RU2000111495/14A patent/RU2191020C2/ru not_active IP Right Cessation
- 1998-10-09 AT AT98952186T patent/ATE269098T1/de not_active IP Right Cessation
- 1998-10-09 EP EP98952186A patent/EP1027053B1/fr not_active Expired - Lifetime
- 1998-10-09 DE DE69824619T patent/DE69824619T2/de not_active Expired - Fee Related
- 1998-10-09 WO PCT/US1998/021313 patent/WO1999018961A1/fr not_active Ceased
- 1998-10-09 SK SK467-2000A patent/SK285332B6/sk unknown
- 1998-10-09 PT PT98952186T patent/PT1027053E/pt unknown
- 1998-10-09 DK DK98952186T patent/DK1027053T3/da active
2000
- 2000-04-07 NO NO20001828A patent/NO20001828L/no unknown

Also Published As

Publication number	Publication date
CZ20001274A3 (cs)	2001-12-12
SK285332B6 (sk)	2006-11-03
DE69824619D1 (de)	2004-07-22
AU748495B2 (en)	2002-06-06
KR20010030749A (ko)	2001-04-16
NO20001828D0 (no)	2000-04-07
BR9813860A (pt)	2001-03-20
CN1275080A (zh)	2000-11-29
JP2001519392A (ja)	2001-10-23
DE69824619T2 (de)	2005-06-23
HK1026845A1 (en)	2000-12-29
DK1027053T3 (da)	2004-09-06
CN1154492C (zh)	2004-06-23
RU2191020C2 (ru)	2002-10-20
PL191993B1 (pl)	2006-08-31
PT1027053E (pt)	2004-09-30
NZ503493A (en)	2001-11-30
HUP0003904A1 (hu)	2001-08-28
PL339774A1 (en)	2001-01-02
SK4672000A3 (en)	2001-09-11
IL135235A0 (en)	2001-05-20
ATE269098T1 (de)	2004-07-15
US6187745B1 (en)	2001-02-13
UA65587C2 (en)	2004-04-15
EP1027053A1 (fr)	2000-08-16
EP1027053A4 (fr)	2002-05-22
AU9794398A (en)	1999-05-03
EP1027053B1 (fr)	2004-06-16
CA2304374A1 (fr)	1999-04-22
WO1999018961A1 (fr)	1999-04-22
NO20001828L (no)	2000-05-15
KR100515196B1 (ko)	2005-09-16
HUP0003904A3 (en)	2006-06-28
ES2221714T3 (es)	2005-01-01

Legal Events

Date	Code	Title	Description
2000-06-30	PD00	Pending as of 2000-06-30 in czech republic
2008-04-23	MM4A	Patent lapsed due to non-payment of fee	Effective date: 20071009

Publication	Publication Date	Title
CZ20001274A3 (cs)	2001-12-12	Lék pro prevenci nefrotoxicity nebo renální dysfunkce nebo sníľení jejich rozvoje a farmaceutický prostředek
JP4149905B2 (ja)	2008-09-17	サイクロスポリンａおよび４０−ｏ−（２−ヒドロキシエチル）−ラパマイシンを含む移植拒絶、自己免疫疾患または炎症性状態の処置用医薬組成物
MXPA04010170A (es)	2005-02-03	Medicamento para prevenir y/o tratar el rechazo cronico.
Bennett	1996	Mechanisms of acute and chronic nephrotoxicity from immunosuppressive drugs
Pally et al.	2001	Tolerability profile of sodium mycophenolate (ERL080) and mycophenolate mofetil with and without cyclosporine (Neoral) in the rat
Dias et al.	1998	Oral administration of rapamycin and cyclosporine differentially alter intestinal function in rabbits
US6355639B1 (en)	2002-03-12	Reverse prenyl compounds as immunosuppressants
Tejani et al.	1988	NEPHROTOXICITY OF CYCLOSPORINE A AND CYCLOSPORINE G IN A RAT MODEL1
Aharoni et al.	2005	Combined treatment of glatiramer acetate and low doses of immunosuppressive drugs is effective in the prevention of graft rejection
Nakamura et al.	2018	Replacement of mycophenolate mofetil with a JAK inhibitor, AS2553627, in combination with low-dose tacrolimus, for renal allograft rejection in non-human primates
Nikolova et al.	2001	Efficacy of SDZ RAD compared with CsA monotherapy and combined RAD/FTY720 treatment in a murine cardiac allotransplantation model
ES2261447T3 (es)	2006-11-16	Antagonistas no peptidicos del receptor ccr1 en combinacion con ciclosporina a para el tratamiento del rechazo de los transplantes de corazon.
MXPA00003194A (en)	2002-02-26	Method of preventing nephrotoxicity caused by cyclosporins and tacrolimus
HK1026845B (en)	2004-12-10	Method of preventing nephrotoxicity caused by cyclosporins or tacrolimus
Li et al.	2004	Synergistic effect of triptolide and tacrolimus on rat cardiac allotransplantation
AU2001261248A1 (en)	2001-11-20	Immunosuppressive compositions comprising an immunophilin-binding compound and a gingkolide compound
WO2006033024A2 (fr)	2006-03-30	Procede de maximisation de l'efficacite et de prevision et minimisation de la toxicite de composes inhibiteurs de calcineurine
Kim et al.	2004	Reduction of chronic ciclosporin nephrotoxicity by thromboxane synthase inhibition with OKY-046
EP1641482A1 (fr)	2006-04-05	Methode de traitement de lesions systemiques consecutives a des brulures
CN1236617A (zh)	1999-12-01	一种免疫抑制药物
AU2004241673A1 (en)	2004-12-02	Method of treatment of systemic injury secondary to burns
HK1148665A1 (en)	2011-09-16	Non-immunosuppressive cyclosporin for the treatment of muscular dystrophy
HK1148665B (en)	2013-08-02	Non-immunosuppressive cyclosporin for the treatment of muscular dystrophy