DD294265A5 - Substituierte aminoalkylphosphinsaeuren und verfahren zu deren herstellung - Google Patents

Substituierte aminoalkylphosphinsaeuren und verfahren zu deren herstellung Download PDF

Info

Publication number
DD294265A5
DD294265A5 DD90340576A DD34057690A DD294265A5 DD 294265 A5 DD294265 A5 DD 294265A5 DD 90340576 A DD90340576 A DD 90340576A DD 34057690 A DD34057690 A DD 34057690A DD 294265 A5 DD294265 A5 DD 294265A5
Authority
DD
German Democratic Republic
Prior art keywords
acid
hydrogen
amino
formula
salt
Prior art date
Application number
DD90340576A
Other languages
German (de)
English (en)
Inventor
Roger G Hall
Ludwig Maier
Wolfgang Froestl
Original Assignee
����`��@���k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ����`��@���k�� filed Critical ����`��@���k��
Publication of DD294265A5 publication Critical patent/DD294265A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/36Amides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301Acyclic saturated acids which can have further substituents on alkyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Luminescent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
DD90340576A 1989-05-13 1990-05-11 Substituierte aminoalkylphosphinsaeuren und verfahren zu deren herstellung DD294265A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898911017A GB8911017D0 (en) 1989-05-13 1989-05-13 Substituted aminoalkylphosphinic acids

Publications (1)

Publication Number Publication Date
DD294265A5 true DD294265A5 (de) 1991-09-26

Family

ID=10656689

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90340576A DD294265A5 (de) 1989-05-13 1990-05-11 Substituierte aminoalkylphosphinsaeuren und verfahren zu deren herstellung

Country Status (24)

Country Link
EP (1) EP0399949B1 (fr)
JP (1) JP2930366B2 (fr)
KR (1) KR0159501B1 (fr)
AT (1) ATE121095T1 (fr)
AU (1) AU629335B2 (fr)
CA (1) CA2016631C (fr)
DD (1) DD294265A5 (fr)
DE (1) DE69018514T2 (fr)
DK (1) DK0399949T3 (fr)
ES (1) ES2070303T3 (fr)
FI (1) FI94416C (fr)
GB (1) GB8911017D0 (fr)
GR (1) GR3015770T3 (fr)
HR (1) HRP940178A2 (fr)
HU (1) HU206885B (fr)
IE (1) IE66165B1 (fr)
IL (1) IL94317A (fr)
MX (1) MX20639A (fr)
NO (1) NO176761C (fr)
NZ (1) NZ233647A (fr)
PT (1) PT94014B (fr)
SI (1) SI9010917B (fr)
YU (1) YU91790A (fr)
ZA (1) ZA903611B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0543780A3 (en) * 1991-11-21 1993-09-01 Ciba-Geigy Ag Novel aminoalkanephosphinic acids and their salts
PL189872B1 (pl) 1996-07-24 2005-10-31 Warner Lambert Co Zastosowanie izobutylogaby i jej pochodnych do wytwarzania leku do leczenia bólu
BR9912062A (pt) 1998-07-15 2001-04-03 Hassan Jomaa Compostos orgânicos fosforosos e seu uso
GB9906882D0 (en) * 1999-03-25 1999-05-19 Novartis Ag Organic compounds
SE9904508D0 (sv) 1999-12-09 1999-12-09 Astra Ab New compounds
SE9904507D0 (sv) 1999-12-09 1999-12-09 Astra Ab New compounds
US7319095B2 (en) 1999-12-09 2008-01-15 Astrazeneca Ab Use of GABAB receptor agonists
SE0102055D0 (sv) * 2001-06-08 2001-06-08 Astrazeneca Ab New Compounds
AR033779A1 (es) 2001-06-08 2004-01-07 Astrazeneca Ab Compuestos utiles en la enfermedad de reflujo
PL1691811T3 (pl) 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
SE0401653D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab New compounds
CA2632021A1 (fr) 2005-12-23 2007-06-28 Astrazeneca Ab Modulateurs des recepteurs gaba-b
KR20080091452A (ko) 2005-12-23 2008-10-13 아스트라제네카 아베 위장 장애의 치료를 위한 이미다졸 유도체
DE102008056228A1 (de) * 2008-11-06 2010-05-12 Clariant International Limited Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, deren Salze und Ester und ihre Verwendung
DE102008056339A1 (de) * 2008-11-07 2010-05-12 Clariant International Limited Verfahren zur Herstellung von mono-aminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
WO2011113904A1 (fr) 2010-03-17 2011-09-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Médicaments pour la prévention et le traitement d'une maladie associée à la dégénérescence des cellules ganglionnaires rétiniennes
DK2621282T3 (da) 2010-09-28 2020-05-04 Univ California Gaba-agonister i behandlingen af forstyrrelser forbundet med metabolisk syndrom og gaba-kombinationer i behandling eller profylakse af type i diabetes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3311475C1 (de) * 1983-03-29 1984-08-16 Siemens AG, 1000 Berlin und 8000 München Mikroprogramm-Steuereinrichtung
DE3312165A1 (de) * 1983-04-02 1984-10-04 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von phosphinothricin
GB8728483D0 (en) * 1987-12-04 1988-01-13 Ciba Geigy Ag Chemical compounds
GB8820266D0 (en) * 1988-08-26 1988-09-28 Smith Kline French Lab Compounds

Also Published As

Publication number Publication date
NO176761C (no) 1995-05-24
JP2930366B2 (ja) 1999-08-03
NZ233647A (en) 1992-08-26
ZA903611B (en) 1991-02-27
PT94014B (pt) 1996-12-31
GR3015770T3 (en) 1995-07-31
IE66165B1 (en) 1995-12-13
CA2016631A1 (fr) 1990-11-13
IL94317A (en) 1997-07-13
MX20639A (es) 1993-12-01
GB8911017D0 (en) 1989-06-28
HU903012D0 (en) 1990-09-28
EP0399949A1 (fr) 1990-11-28
YU91790A (sh) 1992-07-20
FI902368A0 (fi) 1990-05-11
HUT53656A (en) 1990-11-28
NO902109D0 (no) 1990-05-11
KR0159501B1 (ko) 1999-01-15
NO176761B (no) 1995-02-13
ATE121095T1 (de) 1995-04-15
CA2016631C (fr) 2000-08-29
FI94416C (fi) 1995-09-11
FI94416B (fi) 1995-05-31
DE69018514D1 (de) 1995-05-18
JPH0395195A (ja) 1991-04-19
NO902109L (no) 1990-11-14
AU629335B2 (en) 1992-10-01
PT94014A (pt) 1991-01-08
KR900018124A (ko) 1990-12-20
IE901716L (en) 1990-11-13
HRP940178A2 (en) 1996-08-31
ES2070303T3 (es) 1995-06-01
IL94317A0 (en) 1991-03-10
HU206885B (en) 1993-01-28
SI9010917B (sl) 1999-10-31
DE69018514T2 (de) 1995-09-21
DK0399949T3 (da) 1995-07-03
SI9010917A (en) 1997-06-30
EP0399949B1 (fr) 1995-04-12
AU5480990A (en) 1990-11-15

Similar Documents

Publication Publication Date Title
DE69032020T2 (de) N-Substituierte 4-Pyrimidinamine und -Pyrimidindiamine, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel
DE3889638T2 (de) Substituierte Propanphosphinsäure-Verbindungen.
DD294265A5 (de) Substituierte aminoalkylphosphinsaeuren und verfahren zu deren herstellung
EP0830863B1 (fr) Médicaments améliorateurs de l'irrigation sanguine gastrointestinale
DE2445584C3 (de) L- bzw. DL-2-Methyl-3- (3', 4'-dihydroxyphenyl)-alanin-ester, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE4213919A1 (de) Cyclische iminoderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPH0631275B2 (ja) 置換プロパン‐亜ホスホン酸化合物及びその製造方法並びにそれを含有する医薬
EP2427425B1 (fr) Composés de tétracycline
EP0082364B1 (fr) (+)-2-(1-(2,6-dichlorophénoxy)-éthyl)-1,3-diazacyclopent-2-ène, procédé de préparation et application en compositions pharmaceutiques
DE69426835T2 (de) Derivate von 2-arylalkenyl-azacyclo alkan als sigma rezeptor-liganden, verfahren zu ihrer herstellung und ihrer therapeutischer anwendung
DE60002733T2 (de) Diester prodrugs von decahydroischinoline-3-carbonsäure
DE69614075T2 (de) Inhibitoren von Mehrfachresistenzen
US5281747A (en) Substituted aminoalkylphosphinic acids
US5567840A (en) Substituted aminoalkylphosphinic acids
DE3872213T2 (de) 5-substituierte ornithin-derivate.
DE69016270T2 (de) P-substituierte Propanphosphinsäureverbindungen.
DD279238A5 (de) Verfahren zur herstellung von benzocycloheptenderivaten
DD282016A5 (de) Verfahren zur herstellung neuer ungesaettigter aminosaeureverbindungen
EP0391850B1 (fr) Dérivés amino-dicarboxyliques insaturés
DE2019344A1 (de) 4-Chlor-zimtsaeure-(4'-hydroxypiperidid)
DE2730524A1 (de) Peptidderivate und deren herstellung
EP0478941B1 (fr) Médicament contenant des dérivés cyclohexène-2-1-yl-amine substitués et leur utilisation dans la lutte contre les maladies
EP0576396A1 (fr) Composés d'amidine et nouveaux composés d'amidine et leurs utilisation pour le traîtement des troubles du Métabolisme calcique
LU80671A1 (de) Peptidderivate und deren herstellung
WO1993024461A1 (fr) Derives de la tetrahydro- et de la perhydroisoquinoleine et agents therapeutiques les contenant

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee