DD299427A5 - Neue 1-oxa-2-oxo-8-aza-spiro(4,5)dekan-derivate und verfahren zu ihrer herstellung - Google Patents

Neue 1-oxa-2-oxo-8-aza-spiro(4,5)dekan-derivate und verfahren zu ihrer herstellung Download PDF

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Publication number: DD299427A5
Authority: DD; German Democratic Republic
Prior art keywords: general formula; group; oxo; above meaning; oxa
Prior art date: 1989-08-10

Application number

DD90343353A

Other languages

German (de)

English (en)

Inventor

Edit Toth

Jozsef Toerley

Bela Hegedues

Laszlo Szporny

Bela Kiss

Eva Palosi

Dora Groo

Istvan Laszlovszky

Erzsebet Lapis

Adam Sarkadi

Andras Ambrus

Judit Laszy

Original Assignee

��@��@��@��@��Kk��

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-10

Filing date

1990-08-09

Publication date

1992-04-16

1990-08-09 Application filed by ��@��@��@��@��Kk�� filed Critical ��@��@��@��@��Kk��

1992-04-16 Publication of DD299427A5 publication Critical patent/DD299427A5/de

Links

238000000034 method Methods 0.000 title claims abstract description 35
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238000004809 thin layer chromatography Methods 0.000 description 1
150000003626 triacylglycerols Chemical class 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
YFTHZRPMJXBUME-UHFFFAOYSA-N tripropylamine Chemical compound CCCN(CCC)CCC YFTHZRPMJXBUME-UHFFFAOYSA-N 0.000 description 1
235000019871 vegetable fat Nutrition 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DD90343353A 1989-08-10 1990-08-09 Neue 1-oxa-2-oxo-8-aza-spiro(4,5)dekan-derivate und verfahren zu ihrer herstellung DD299427A5 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU894093A HU204529B (en)	1989-08-10	1989-08-10	Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
DD299427A5 true DD299427A5 (de)	1992-04-16

Family

ID=10966862

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DD90343353A DD299427A5 (de)	1989-08-10	1990-08-09	Neue 1-oxa-2-oxo-8-aza-spiro(4,5)dekan-derivate und verfahren zu ihrer herstellung

Country Status (13)

Country	Link
EP (1)	EP0414422B1 (fr)
JP (1)	JPH0377885A (fr)
KR (1)	KR950001022B1 (fr)
AT (1)	ATE103921T1 (fr)
AU (1)	AU623545B2 (fr)
DD (1)	DD299427A5 (fr)
DE (1)	DE69007905T2 (fr)
DK (1)	DK0414422T3 (fr)
ES (1)	ES2052181T3 (fr)
HU (1)	HU204529B (fr)
IL (1)	IL95321A (fr)
NZ (1)	NZ234845A (fr)
ZA (1)	ZA906301B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU204530B (en) *	1989-08-10	1992-01-28	Richter Gedeon Vegyeszet	Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
KR940003491B1 (ko) *	1989-08-10	1994-04-23	리히터 게데온 베기에스제티 기아르 알.티	4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물
HU204054B (en) *	1989-08-10	1991-11-28	Richter Gedeon Vegyeszet	Process for producing new 1-oxa-2-oxo-8-azaspiro(4,5)decane derivatives and pharmaceutical compositions comprising same
YU150489A (sh) *	1989-08-10	1992-12-21	W.L. Gore & Co. Gmbh.	Uređaj za ispitivanje odevnih predmeta na nepromočivost
FR2691459B1 (fr) *	1992-05-25	1995-06-09	Adir	Nouveaux derives de la phenothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US7364752B1 (en)	1999-11-12	2008-04-29	Abbott Laboratories	Solid dispersion pharamaceutical formulations
EP1175205B1 (fr)	1999-11-12	2006-06-14	Abbott Laboratories	Dispersion solide comrpenant ritonavir, fenofibrate ou griseofulvin
DE10026698A1 (de)	2000-05-30	2001-12-06	Basf Ag	Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US8377952B2 (en)	2003-08-28	2013-02-19	Abbott Laboratories	Solid pharmaceutical dosage formulation
US8025899B2 (en)	2003-08-28	2011-09-27	Abbott Laboratories	Solid pharmaceutical dosage form
WO2005032228A1 (fr)	2003-09-26	2005-04-07	Sony Computer Entertainment Inc.	Dispositif electronique portable
RU2006132465A (ru) *	2004-02-10	2008-03-20	Ф.Хоффманн-Ля Рош Аг (Ch)	Модуляторы хемокинового рецептора ccr5
WO2008119663A1 (fr)	2007-03-29	2008-10-09	F. Hoffmann-La Roche Ag	Composés hétérocycliques antiviraux
CA3094481A1 (fr)	2018-04-06	2019-10-10	Camp4 Therapeutics Corporation	Derives de phenothiazine et leurs utilisations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1256404A (en) *	1968-06-07	1971-12-08	Dainippon Pharmaceutical Co	0-oxa-3,8-diazaspiro(4,5)decan-2,4-diones
DE2118339A1 (de) *	1971-04-15	1972-10-26	Yoshitomi Pharmaceutical Industries Ltd, Osaka (Japan)	Pipendinspiroverbindungen
US4255432A (en) *	1979-09-06	1981-03-10	Syntex (U.S.A.) Inc.	8-[2-3-Indolyl)ethyl]-1-oxa-3-,8-diazaspiro[4.5]decan-2-ones, pharmaceutical compositions thereof and methods of use thereof
FR2615515B1 (fr) *	1987-05-22	1989-06-30	Adir	Nouveaux derives du spiro 4, 5 decane, leur procede de preparation et les compositions pharmaceutiques les renfermant
YU150489A (sh) *	1989-08-10	1992-12-21	W.L. Gore & Co. Gmbh.	Uređaj za ispitivanje odevnih predmeta na nepromočivost

1989
- 1989-08-10 HU HU894093A patent/HU204529B/hu not_active IP Right Cessation
1990
- 1990-08-09 JP JP2209359A patent/JPH0377885A/ja active Pending
- 1990-08-09 DK DK90308785.6T patent/DK0414422T3/da active
- 1990-08-09 AT AT90308785T patent/ATE103921T1/de not_active IP Right Cessation
- 1990-08-09 ZA ZA906301A patent/ZA906301B/xx unknown
- 1990-08-09 IL IL9532190A patent/IL95321A/en not_active IP Right Cessation
- 1990-08-09 KR KR1019900012255A patent/KR950001022B1/ko not_active Expired - Lifetime
- 1990-08-09 EP EP90308785A patent/EP0414422B1/fr not_active Expired - Lifetime
- 1990-08-09 DE DE69007905T patent/DE69007905T2/de not_active Expired - Fee Related
- 1990-08-09 DD DD90343353A patent/DD299427A5/de not_active IP Right Cessation
- 1990-08-09 NZ NZ234845A patent/NZ234845A/en unknown
- 1990-08-09 ES ES90308785T patent/ES2052181T3/es not_active Expired - Lifetime
- 1990-08-09 AU AU60802/90A patent/AU623545B2/en not_active Ceased

Also Published As

Publication number	Publication date
HU204529B (en)	1992-01-28
DE69007905D1 (de)	1994-05-11
EP0414422B1 (fr)	1994-04-06
AU6080290A (en)	1991-02-14
ES2052181T3 (es)	1994-07-01
ATE103921T1 (de)	1994-04-15
EP0414422A3 (en)	1991-07-24
KR950001022B1 (ko)	1995-02-07
DE69007905T2 (de)	1994-07-21
IL95321A0 (en)	1991-06-30
HUT55784A (en)	1991-06-28
JPH0377885A (ja)	1991-04-03
IL95321A (en)	1994-02-27
DK0414422T3 (da)	1994-05-16
ZA906301B (en)	1991-06-26
KR910004633A (ko)	1991-03-29
AU623545B2 (en)	1992-05-14
EP0414422A2 (fr)	1991-02-27
NZ234845A (en)	1992-03-26

Legal Events

Date	Code	Title	Description
1998-08-27	ENJ	Ceased due to non-payment of renewal fee

Publication	Publication Date	Title
DE69106365T2 (de)	1995-05-04	Chinuclidinderivate.
DD299431A5 (de)	1992-04-16	Neue 2-oxo-3,8-diaza-spiro[4,5]dekan-derivate und verfahren zur herstellung dieser verbindungen
DE3342164C2 (fr)	1989-03-02
DE3736664A1 (de)	1989-05-11	Tetrahydro-furo- und -thieno(2,3-c)pyridine, ihre verwendung als arzneimittel und verfahren zu ihrer herstellung
EP0528922B1 (fr)	1999-06-16	Nouveaux composes de sulfonyle
DD299427A5 (de)	1992-04-16	Neue 1-oxa-2-oxo-8-aza-spiro(4,5)dekan-derivate und verfahren zu ihrer herstellung
DE3008944A1 (de)	1981-09-24	Dibenzimidazoazepine, ihre herstellung und verwendung
DE1470157A1 (de)	1969-05-14	Verfahren zur Herstellung substituierter Thioxanthensulfonamide und ihrer Saeureanlagerungssalze
DD149071A5 (de)	1981-06-24	Herstellung 2-substituierter trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido eckige klammer auf 4,3-b eckige klammer zu indole
DD300105A5 (de)	1992-05-21	Neue R(-)3-Quinuliclidinol - Derivate
DE69007900T2 (de)	1994-07-21	4,4-Disubstituierte Piperidinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen.
EP0288048A2 (fr)	1988-10-26	Dérivés de benzo- et thiéno-3,4-dihydropyridine, procédés pour leur préparation et médicaments les contenant
EP0461574B1 (fr)	1997-09-24	Médicaments contenant des 3,7-diazabicyclo(3,3,1)nonanes
EP0519291A1 (fr)	1992-12-23	2,3-Dihydropyrano (2,3-b) pyridines amino-méthyl-substituées, procédé pour leur préparation et leur utilisation en tant que médicaments
DE68905363T2 (de)	1993-08-05	Heterotetracyclische laktamderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen, die sie enthalten.
DE2749584A1 (de)	1978-05-18	Ueberbrueckte geminale diphenylpiperidine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DD257430A5 (de)	1988-06-15	Verfahren zur herstellung von pyrrolo(1,2-a)(4,1)benzoxarepinen
DE69617001T2 (de)	2002-07-11	(2-morpholinylmethyl)benzamid-derivate
WO1982002891A1 (fr)	1982-09-02	Amino-2, 1, 3-benzothiadiazol et derives benzoxadiazol, leur preparation et medicaments les renfermant
DE69007904T2 (de)	1994-07-21	1-Oxa-2-oxo-8-azaspiro[4,5]decan-Derivate, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen daraus.
CH666031A5 (de)	1988-06-30	Naphthoxazine, ihre herstellung und pharmazeutische zusammensetzungen.
AT395852B (de)	1993-03-25	Imidazolyl-methyl-tetrahydrothiophenderivate
DD299430A5 (de)	1992-04-16	Neue 1-oxa-2-oxo-8-aza-spiro[4,5]dekan-derivate und verfahren zu ihrer herstellung
DE3103080A1 (de)	1981-12-17	"spiro (dihydrobenzofuran-piperidine und -pyrrolidine)"
DD139581A5 (de)	1980-01-09	Verfahren zur herstellung neuer 4-phenyl-thieno-eckige klammer auf 2,3-c eckige klammer zu-piperidine