DK0414007T3 - Hidtil ukendt arginindeiminase, dens fremstillingsmetode og et anti-cancermiddel indeholdende dette enzym som en effektiv ingrediens - Google Patents

Hidtil ukendt arginindeiminase, dens fremstillingsmetode og et anti-cancermiddel indeholdende dette enzym som en effektiv ingrediens

Info

Publication number: DK0414007T3
Authority: DK; Denmark
Prior art keywords: enzyme; cancer agent; preparation; agent containing; arginine deiminase
Prior art date: 1989-08-02

Application number

DK90114846.0T

Other languages

English (en)

Inventor

Haruo Takaku

Kaoru Miyazaki

Miho Aoshima

Original Assignee

Japan Energy Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-02

Filing date

1990-08-02

Publication date

1995-09-04

1990-08-02 Application filed by Japan Energy Corp filed Critical Japan Energy Corp

1995-09-04 Application granted granted Critical

1995-09-04 Publication of DK0414007T3 publication Critical patent/DK0414007T3/da

Links

108090000790 Enzymes Proteins 0.000 title abstract 3
102000004190 Enzymes Human genes 0.000 title abstract 3
108010082340 Arginine deiminase Proteins 0.000 title abstract 2
239000002246 antineoplastic agent Substances 0.000 title abstract 2
239000004615 ingredient Substances 0.000 title 1
241000204031 Mycoplasma Species 0.000 abstract 2
239000004475 Arginine Substances 0.000 abstract 1
230000001093 anti-cancer Effects 0.000 abstract 1
ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 abstract 1
238000000338 in vitro Methods 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Enzymes And Modification Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK90114846.0T 1989-08-02 1990-08-02 Hidtil ukendt arginindeiminase, dens fremstillingsmetode og et anti-cancermiddel indeholdende dette enzym som en effektiv ingrediens DK0414007T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP20090289		1989-08-02

Publications (1)

Publication Number	Publication Date
DK0414007T3 true DK0414007T3 (da)	1995-09-04

Family

ID=16432163

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90114846.0T DK0414007T3 (da)	1989-08-02	1990-08-02	Hidtil ukendt arginindeiminase, dens fremstillingsmetode og et anti-cancermiddel indeholdende dette enzym som en effektiv ingrediens

Country Status (12)

Country	Link
US (1)	US5474928A (da)
EP (1)	EP0414007B1 (da)
JP (1)	JP2900279B2 (da)
AT (1)	ATE125295T1 (da)
CA (1)	CA2022177C (da)
DE (1)	DE69020979T2 (da)
DK (1)	DK0414007T3 (da)
ES (1)	ES2078277T3 (da)
FI (1)	FI903826A7 (da)
IE (1)	IE62120B1 (da)
NO (1)	NO178734C (da)
PT (1)	PT94882B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998024473A1 (fr) *	1996-12-03	1998-06-11	Kyowa Hakko Kogyo Co., Ltd.	Inhibiteur de fibrose des tissus
US5804183A (en) *	1997-01-31	1998-09-08	Enzon, Inc.	Arginine deminase derived from mycoplasma arthritidis and polymer conjugates containing the same
US6183738B1 (en)	1997-05-12	2001-02-06	Phoenix Pharamacologics, Inc.	Modified arginine deiminase
US6635462B1 (en) *	1997-05-12	2003-10-21	Phoenix Pharmacologies, Inc.	Mutated form of arginine deiminase
US6180387B1 (en) *	1997-08-11	2001-01-30	Smithkline Beecham Corporation	Arginine deiminase
IT1298918B1 (it) *	1998-02-20	2000-02-07	Mendes Srl	Uso di batteri dotati di arginina deiminasi per indurre apoptosi e/o ridurre una reazione infiammatoria e composizioni farmaceutiche
AU2001275810A1 (en) *	2000-07-27	2002-02-13	Angiolab, Inc.	The pharmaceutical composition comprising arginine deiminase for inhibiting angiogenesis
CA2506244C (en) *	2002-11-18	2012-10-30	Phoenix Pharmacologics, Inc.	Methods for inhibiting viral replication in vivo
FR2884717B1 (fr)	2005-04-25	2009-07-03	Erytech Pharma Soc Par Actions	Erythrocytes renfermant de l'arginine deiminase
CN101002945B (zh)	2006-01-20	2012-09-05	清华大学	一种用于肿瘤治疗的新型复合物
FR2919804B1 (fr)	2007-08-08	2010-08-27	Erytech Pharma	Composition et vaccin therapeutique anti-tumoral
EP2295560A1 (en)	2009-09-14	2011-03-16	RWTH Aachen University	Directed evolution of arginine deiminase for increased activity at physiological pH
US9255262B2 (en)	2013-03-06	2016-02-09	Vision Global Holdings Ltd.	Albumin-binding arginine deminase and the use thereof
USRE48805E1 (en)	2013-03-06	2021-11-02	Vision Global Holdings Ltd.	Method for cancer targeting treatment and detection of arginine using albumin-binding arginine deiminase fusion protein
EP3744341A1 (en)	2013-03-15	2020-12-02	TDW Group	Arginine deiminase with reduced cross-reactivity toward adi - peg 20 antibodies for cancer treatment
KR102523031B1 (ko)	2014-03-18	2023-04-19	티디더블유 그룹	조작된 키메라성 페길화된 adi 및 사용 방법
US11613759B2 (en)	2015-09-04	2023-03-28	Sqz Biotechnologies Company	Intracellular delivery of biomolecules to cells comprising a cell wall
JP7602702B2 (ja)	2016-05-03	2024-12-19	ステムセルテクノロジーズカナダインコーポレーテッド	寛容性を誘導するための生体分子の細胞内送達
EP3534963B1 (en)	2016-11-02	2024-04-17	Polaris Group	Formulations of pegylated arginine deiminase
EP3449935A1 (en)	2017-08-31	2019-03-06	Erytech Pharma	Arginine deiminase encapsulated inside erythrocytes and their use in treating cancer and arginase-1 deficiency
WO2019042628A1 (en)	2017-08-31	2019-03-07	Erytech Pharma	ARGININE DEIMINASE ENCAPSULATED WITHIN ERYTHROCYTES AND THEIR USE IN THE TREATMENT OF CANCER AND ARGINASE-1 DEFICIENCY

1990
- 1990-07-25 JP JP2197068A patent/JP2900279B2/ja not_active Expired - Fee Related
- 1990-07-27 CA CA002022177A patent/CA2022177C/en not_active Expired - Fee Related
- 1990-07-31 IE IE277190A patent/IE62120B1/en not_active IP Right Cessation
- 1990-08-01 NO NO903398A patent/NO178734C/no unknown
- 1990-08-01 FI FI903826A patent/FI903826A7/fi not_active Application Discontinuation
- 1990-08-01 PT PT94882A patent/PT94882B/pt not_active IP Right Cessation
- 1990-08-02 AT AT90114846T patent/ATE125295T1/de not_active IP Right Cessation
- 1990-08-02 DK DK90114846.0T patent/DK0414007T3/da active
- 1990-08-02 EP EP90114846A patent/EP0414007B1/en not_active Expired - Lifetime
- 1990-08-02 DE DE69020979T patent/DE69020979T2/de not_active Expired - Lifetime
- 1990-08-02 ES ES90114846T patent/ES2078277T3/es not_active Expired - Lifetime
1994
- 1994-02-25 US US08/201,724 patent/US5474928A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0414007A2 (en)	1991-02-27
EP0414007A3 (en)	1991-03-20
NO903398L (no)	1991-02-04
PT94882B (pt)	1997-07-31
US5474928A (en)	1995-12-12
NO903398D0 (no)	1990-08-01
NO178734B (no)	1996-02-12
FI903826A0 (fi)	1990-08-01
ATE125295T1 (de)	1995-08-15
NO178734C (no)	1996-05-22
IE62120B1 (en)	1994-12-14
DE69020979T2 (de)	1996-01-04
EP0414007B1 (en)	1995-07-19
CA2022177C (en)	2001-02-27
CA2022177A1 (en)	1991-02-03
FI903826A7 (fi)	1991-02-03
IE902771A1 (en)	1991-02-27
JPH03164173A (ja)	1991-07-16
ES2078277T3 (es)	1995-12-16
DE69020979D1 (de)	1995-08-24
JP2900279B2 (ja)	1999-06-02
PT94882A (pt)	1991-05-22

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