DK0448930T3 - Stabile præparater til parenteral administration og fremgangsmåde til fremstilling deraf - Google Patents

Stabile præparater til parenteral administration og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0448930T3
DK0448930T3 DK91100650.0T DK91100650T DK0448930T3 DK 0448930 T3 DK0448930 T3 DK 0448930T3 DK 91100650 T DK91100650 T DK 91100650T DK 0448930 T3 DK0448930 T3 DK 0448930T3
Authority
DK
Denmark
Prior art keywords
preparation
methods
parenteral administration
stable preparations
preparations
Prior art date
Application number
DK91100650.0T
Other languages
Danish (da)
English (en)
Inventor
William Steber
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of DK0448930T3 publication Critical patent/DK0448930T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DK91100650.0T 1990-03-30 1991-01-21 Stabile præparater til parenteral administration og fremgangsmåde til fremstilling deraf DK0448930T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/502,382 US5213810A (en) 1990-03-30 1990-03-30 Stable compositions for parenteral administration and method of making same

Publications (1)

Publication Number Publication Date
DK0448930T3 true DK0448930T3 (da) 1994-06-20

Family

ID=23997559

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91100650.0T DK0448930T3 (da) 1990-03-30 1991-01-21 Stabile præparater til parenteral administration og fremgangsmåde til fremstilling deraf

Country Status (28)

Country Link
US (1) US5213810A (es)
EP (1) EP0448930B1 (es)
JP (1) JP2966564B2 (es)
KR (1) KR0159778B1 (es)
CN (1) CN1063941C (es)
AR (1) AR248085A1 (es)
AT (1) ATE106240T1 (es)
AU (1) AU641994B2 (es)
BG (1) BG60850B1 (es)
CA (1) CA2039491C (es)
CZ (1) CZ283053B6 (es)
DE (1) DE69102176T2 (es)
DK (1) DK0448930T3 (es)
ES (1) ES2054380T3 (es)
FI (1) FI101676B1 (es)
HU (1) HU219584B (es)
IE (1) IE65970B1 (es)
IL (1) IL97145A (es)
MX (1) MX172602B (es)
NO (1) NO300717B1 (es)
NZ (1) NZ237509A (es)
PL (1) PL167692B1 (es)
PT (1) PT97160B (es)
RO (1) RO106191B1 (es)
RU (1) RU2011377C1 (es)
SK (1) SK279461B6 (es)
YU (1) YU47650B (es)
ZA (1) ZA912398B (es)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69208765T2 (de) * 1991-07-23 1996-09-26 American Cyanamid Co Stabile Zusammensetzungen für parenterale Verabrechung und ihre Verwendung
US5599660A (en) * 1993-01-19 1997-02-04 Pharmacia Biotech Inc. Method and preparation for sequential delivery of wax-embedded, inactivated biological and chemical reagents
AU6029694A (en) * 1993-01-19 1994-08-15 Pharmacia P-L Biochemicals, Inc. Storage and delivery of purified protein reagents with carrier wax
US5683720A (en) * 1994-10-28 1997-11-04 Fuisz Technologies Ltd. Liquiflash particles and method of making same
US6083430A (en) * 1994-10-28 2000-07-04 Fuisz Technologies Ltd. Method of preparing a dosage unit by direct tableting and product therefrom
DE69616167T2 (de) * 1995-06-29 2002-06-20 Societe Des Produits Nestle S.A., Vevey Verfahren zur Verkapselung eines Kernmaterials mit einem Polymer durch Hochdruckbehandlung
ES2236943T3 (es) 1997-09-19 2005-07-16 Shire Laboratories Inc. Perlas de disolucion solida.
AU2002300572B2 (en) * 1997-09-19 2004-11-25 Shire Laboratories, Inc. Solid Solution Beadlet
US6117452A (en) * 1998-08-12 2000-09-12 Fuisz Technologies Ltd. Fatty ester combinations
US8663692B1 (en) * 1999-05-07 2014-03-04 Pharmasol Gmbh Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same
TR200103188T2 (tr) * 1999-05-07 2002-04-22 Pharmasol Gmbh Sıvı ve katı lipit karışımları temelli lipid parçacıklar.
JP4980527B2 (ja) * 1999-06-07 2012-07-18 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 酸に不安定な活性化合物を含有する新規の製剤および投与形
IES990700A2 (en) * 1999-08-18 2001-08-22 Kinerton Ltd Process to make a sustained release formulation
ES2209948T3 (es) * 1999-08-18 2004-07-01 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Formulacion de un peptico de liberacion sostenida.
AU2001257359A1 (en) 2000-04-27 2001-11-07 Verion Inc. Zero order release and temperature-controlled microcapsules and process for the preparation thereof
EP1299003B2 (en) * 2000-06-26 2015-02-25 DSM IP Assets B.V. Improved methods of incorporating polyunsaturated fatty acids in milk
JP2004509739A (ja) 2000-09-27 2004-04-02 ベリオン　インコーポレイテッド 即時水溶解性カプセルおよびその製法
DE60133706T2 (de) * 2000-10-10 2009-07-02 Wyeth Holdings Corp. Stabilisierte Arzneizusammensetzungen zur parenteralen Vearbreichung
FR2852843B1 (fr) 2003-03-24 2008-05-23 Karim Ioualalen Systeme galenique permettant le masquage du gout
CA2547239A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Azithromycin multiparticulate dosage forms by liquid-based processes
JP2007513145A (ja) * 2003-12-04 2007-05-24 ファイザー・プロダクツ・インク 医薬用多微粒子の製造方法
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
JP2007513139A (ja) * 2003-12-04 2007-05-24 ファイザー・プロダクツ・インク 安定性の改善した多粒子組成物
CA2549225A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Spray-congeal process using an extruder for preparing multiparticulate crystalline drug compositions containing preferably a poloxamer and a glyceride
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
JP2007513143A (ja) * 2003-12-04 2007-05-24 ファイザー・プロダクツ・インク 押出機を使用して好ましくはポロクサマーおよびグリセリドを含む多粒子アジスロマイシン組成物を製造するための噴霧凝固法
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US8221809B2 (en) * 2006-06-22 2012-07-17 Martek Biosciences Corporation Encapsulated labile compound compositions and methods of making the same
CA2670821C (en) 2006-08-09 2012-05-15 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies
CA2683610C (en) 2007-04-23 2013-01-08 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
WO2009102467A2 (en) 2008-02-13 2009-08-20 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
SMT202000405T1 (it) 2008-09-04 2020-09-10 Amylin Pharmaceuticals Llc Formulazioni a rilascio prolungato usando veicolanti non acquosi
JP5494957B2 (ja) 2009-06-11 2014-05-21 株式会社リコー 静電荷像現像用トナー、現像剤、画像形成方法及び画像形成装置
MX378797B (es) 2009-09-28 2025-03-10 Intarcia Therapeutics Inc Establecimiento y/o terminacion rapidos de suministro de estado estable sustancial de farmaco.
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9364549B2 (en) * 2011-11-30 2016-06-14 Andreas Voigt Hydrophobic drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
EP3003266A2 (en) * 2013-05-29 2016-04-13 Therakine Biodelivery GmbH Hydrophilic microparticles, drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
CN113598842A (zh) 2015-06-03 2021-11-05 因塔西亚制药公司 植入物放置和移除系统
KR102574993B1 (ko) 2016-05-16 2023-09-06 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
WO2018129058A1 (en) 2017-01-03 2018-07-12 Intarcia Therapeutics, Inc. Methods comprising continuous administration of a glp-1 receptor agonist and co-adminstration of a drug
BR112021016432A2 (pt) 2019-02-21 2021-11-09 Chromadex Inc Composição que compreende prills de cera, processo para produzir prills de cera, composição nutricional, alimento, bebida ou suplemento alimentar que compreende prills de cera, e composição que compreende microesferas encapsuladas

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3147187A (en) * 1962-09-10 1964-09-01 Don Hall Lab Sustained release pharmaceutical
CH637297A5 (fr) * 1978-12-05 1983-07-29 Nestle Sa Microbille comprenant un microorganisme et son procede de fabrication.
JPS56140915A (en) * 1980-04-07 1981-11-04 Yamanouchi Pharmaceut Co Ltd Pharmaceutical preparation for solid drug
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
DE3024416C2 (de) * 1980-06-28 1982-04-15 Gödecke AG, 1000 Berlin Verfahren zur Herstellung von Arzneimitteln mit retardierter Wirkstoff-Freisetzung
US4666839A (en) * 1982-12-01 1987-05-19 Amgen Methods and materials for obtaining microbial expression of polypeptides including bovine prolactin
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
US4603044A (en) * 1983-01-06 1986-07-29 Technology Unlimited, Inc. Hepatocyte Directed Vesicle delivery system
US4568559A (en) * 1984-02-06 1986-02-04 Biotek, Inc. Composite core coated microparticles and process of preparing same
US4568536A (en) * 1985-02-08 1986-02-04 Ethicon, Inc. Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition
US4755387A (en) * 1985-03-21 1988-07-05 The Procter & Gamble Company Therapeutic particles
DE3527356A1 (de) * 1985-07-31 1987-02-05 Degussa Verfahren zur verbesserung der fruchtbarkeit von haustieren
SE462894B (sv) * 1985-10-28 1990-09-17 Biogram Ab Mikrokapslar, foerfarande foer framstaellning daerav samt anvaendning
US4837381A (en) * 1986-08-11 1989-06-06 American Cyanamid Company Compositions for parenteral administration and their use
US4911928A (en) * 1987-03-13 1990-03-27 Micro-Pak, Inc. Paucilamellar lipid vesicles

Also Published As

Publication number Publication date
DE69102176T2 (de) 1995-01-05
CZ283053B6 (cs) 1997-12-17
NO911228D0 (no) 1991-03-26
AU7397291A (en) 1991-10-03
AU641994B2 (en) 1993-10-07
HK1000004A1 (en) 1997-10-03
FI911531L (fi) 1991-10-01
FI911531A0 (fi) 1991-03-28
NO911228L (no) 1991-10-01
IE911041A1 (en) 1991-10-09
MX172602B (es) 1993-01-03
HUT59834A (en) 1992-07-28
IL97145A0 (en) 1992-05-25
ATE106240T1 (de) 1994-06-15
IL97145A (en) 1996-06-18
KR0159778B1 (ko) 1998-12-01
FI101676B (fi) 1998-08-14
YU57091A (sh) 1994-01-20
ES2054380T3 (es) 1994-08-01
RO106191B1 (ro) 1993-03-31
BG93923A (bg) 1993-12-24
PL289657A1 (en) 1992-01-13
EP0448930A1 (en) 1991-10-02
PT97160A (pt) 1991-11-29
NO300717B1 (no) 1997-07-14
CA2039491A1 (en) 1991-10-01
KR910016322A (ko) 1991-11-05
RU2011377C1 (ru) 1994-04-30
CN1063941C (zh) 2001-04-04
YU47650B (sh) 1995-12-04
FI101676B1 (fi) 1998-08-14
CA2039491C (en) 2001-09-04
JPH04221319A (ja) 1992-08-11
JP2966564B2 (ja) 1999-10-25
PL167692B1 (en) 1995-10-31
PT97160B (pt) 1998-07-31
IE65970B1 (en) 1995-11-29
SK279461B6 (sk) 1998-11-04
NZ237509A (en) 1993-04-28
EP0448930B1 (en) 1994-06-01
US5213810A (en) 1993-05-25
HU911054D0 (en) 1991-10-28
AR248085A1 (es) 1995-06-30
ZA912398B (en) 1992-01-29
CN1055293A (zh) 1991-10-16
DE69102176D1 (de) 1994-07-07
BG60850B1 (bg) 1996-05-31
HU219584B (hu) 2001-05-28

Similar Documents

Publication Publication Date Title
DK93992D0 (da) Depotpraeparat og fremgangsmaade til fremstilling deraf
NO20000369L (no) Fremstilling av ribozymer og preparater omfattende slike
DK170187A (da) Pharmaceutisk fordelagtigt salt af amlodipin og farmaceutiske praeparater indeholdende dette
DK297089A (da) Pyrimidinderivater og fremgangsmaade til fremstilling deraf
DK10289A (da) Fremgangsmaade og praeparater til forebyggelse af ulcus
DK149988D0 (da) Stabile farmaceutiske praeparater
NO875232L (no) Stabile preparater av ricin-toksin-a-kjede og av rta-immunokonjugater og stabilisator-utsorteringsmetoder derav.
DK210690A (da) Metoder og praeparater til inhibering af blodpladeaggregation
DK130389D0 (da) Catecholderivater og farmaceutiske praeparater omfatende samme
DK0480052T3 (da) Quinolinderivat, antiulcus-lægemiddel indeholdende derivatet og fremstilling af derivatet
DK522688D0 (da) Tricykliske amidinderivater og farmaceutiske praeparater med indhold af saadanne forbindelser
DK430189A (da) Fremgangsmaade til fremstilling af et aromatiseringsmiddel og det fremstillede middel
DK132790A (da) Antiinflammatoriske og analgetiske forbindelser, praeparater deraf og metoder til fremstilling og anvendelse deraf
DK287188D0 (da) Cephalosporinforbindelser og farmaceutisk praeparat deraf
DK522788A (da) Amidinoderivater og farmaceutiske praeparater med indhold af saadanne forbindelser
DK650089A (da) Furanalkylketoner og farmaceutiske praeparater deraf
DK635988D0 (da) 1,3-butandiolacetoacetat-derivater og anvendelse af 1,3-butandiolacetoacetat-forbindelser til fremstilling af farmaceutiske praeparater
DK522888D0 (da) Heterocykliske derivater og farmaceutiske praeparater med indhold af saadanne
DK0512547T3 (da) Smertekontrollerende præparat og fremgangsmåde til fremstilling deraf
DK397788A (da) Polyarylalkan-oligomer-praeparater og fremgangsmaade til fremstilling deraf
DK269289A (da) Cyklopentanderivater og farmaceutiske praeparater indeholdende saadanne forbindelser
DK449188D0 (da) 2'-deoxy-5-fluoruridinderivater og farmaceutiske praeparater med indhold af saadanne forbindelser
DK701588A (da) N-hydroxy-5-phenyl-2-furancarboximidamider og anvendelse heraf til fremstilling af farmceutiske praeparater
NO940250D0 (no) Fluorerte kinoloner, fremgangsmaate for fremstilling og farmasoeytiske preparater inneholdende slike
DK369088D0 (da) Fremgangsmaade til fremstilling af nukleinsyrederivater og fremgangsmaade til fremstilling af farmaceutiske praeparater indeholdende disse