DK0573576T4 - Midler til topisk administration af farmaceutisk aktive stoffer - Google Patents

Midler til topisk administration af farmaceutisk aktive stoffer

Info

Publication number
DK0573576T4
DK0573576T4 DK92907818T DK92907818T DK0573576T4 DK 0573576 T4 DK0573576 T4 DK 0573576T4 DK 92907818 T DK92907818 T DK 92907818T DK 92907818 T DK92907818 T DK 92907818T DK 0573576 T4 DK0573576 T4 DK 0573576T4
Authority
DK
Denmark
Prior art keywords
agents
active substances
pharmaceutically active
topical administration
pharmaceutical agent
Prior art date
Application number
DK92907818T
Other languages
Danish (da)
English (en)
Other versions
DK0573576T3 (da
Inventor
Juan A Mantelle
Original Assignee
Noven Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27098393&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0573576(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Noven Pharma filed Critical Noven Pharma
Publication of DK0573576T3 publication Critical patent/DK0573576T3/da
Application granted granted Critical
Publication of DK0573576T4 publication Critical patent/DK0573576T4/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK92907818T 1991-02-27 1992-02-27 Midler til topisk administration af farmaceutisk aktive stoffer DK0573576T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66182791A 1991-02-27 1991-02-27
US07/813,196 US5234957A (en) 1991-02-27 1991-12-23 Compositions and methods for topical administration of pharmaceutically active agents
PCT/US1992/001730 WO1992015289A1 (fr) 1991-02-27 1992-02-27 Compositions et procedes d'administration locale d'agents pharmaceutiquement actifs

Publications (2)

Publication Number Publication Date
DK0573576T3 DK0573576T3 (da) 1997-04-01
DK0573576T4 true DK0573576T4 (da) 2003-10-27

Family

ID=27098393

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92907818T DK0573576T4 (da) 1991-02-27 1992-02-27 Midler til topisk administration af farmaceutisk aktive stoffer

Country Status (14)

Country Link
US (1) US5234957A (fr)
EP (2) EP0573576B2 (fr)
JP (1) JPH06508820A (fr)
AT (1) ATE144704T1 (fr)
AU (2) AU658870B2 (fr)
CA (1) CA2104474C (fr)
DE (1) DE69214938T3 (fr)
DK (1) DK0573576T4 (fr)
ES (1) ES2094906T5 (fr)
FI (1) FI110161B (fr)
GR (1) GR3022708T3 (fr)
NO (1) NO307363B1 (fr)
SG (2) SG49158A1 (fr)
WO (1) WO1992015289A1 (fr)

Families Citing this family (203)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5549924A (en) 1987-07-17 1996-08-27 Robin Renee Thill Shlenker Method of forming a membrane, especially a latex or polymer membrane, including a deactivating barrier and indicating layer
US5679399A (en) 1987-07-17 1997-10-21 Bio Barrier, Inc. Method of forming a membrane, especially a latex or polymer membrane, including multiple discrete layers
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
GB9101986D0 (en) * 1991-01-30 1991-03-13 Smith & Nephew Pharmaceutical compositions
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6024975A (en) * 1992-04-08 2000-02-15 Americare International Diagnostics, Inc. Method of transdermally administering high molecular weight drugs with a polymer skin enhancer
DE4223004A1 (de) * 1992-07-13 1994-01-20 Liedtke Pharmed Gmbh Einzeldosierte halbfeste topische Arzneiform zur Transdermaltherapie
ES2160623T3 (es) * 1992-12-31 2001-11-16 Sunkyong Ind Ltd Composiciones farmaceuticas mejoradas para la penetracion en la piel de piroxicam.
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
GB9305282D0 (en) * 1993-03-15 1993-05-05 Ucb Sa Enantiomers of 1-(4-chlorophenyl)phenylmethyl)-4-(4-methylphenyl)sulphonyl)piperazine
US5578315A (en) * 1993-12-01 1996-11-26 Rutgers, The State University Of New Jersey Mucosal adhesive device for long-acting delivery of pharmaceutical combinations in oral cavity
US5552153A (en) * 1994-04-28 1996-09-03 Hoffman-La Roche Inc. Pharmaceutical composition for transdermal delivery
US5580574A (en) * 1994-04-28 1996-12-03 Hoffmann-La Roche Inc. Pharmaceutical composition for transdermal delivery
KR0121127B1 (ko) * 1994-05-09 1997-11-13 강박광 이온성 고분자 네트웍을 갖는 피부약물전달체계
ES2137528T3 (es) * 1994-07-05 1999-12-16 Lohmann Therapie Syst Lts Hidrogel para la aplicacion de substancias activas terapeuticas y/o cosmeticas en la piel.
US5585398A (en) * 1994-07-15 1996-12-17 Ernst; Amy A. Topical anesthetic comprising lidocaine, adrenaline, and tetracaine, and its method of use
US6319954B1 (en) 1995-01-13 2001-11-20 Somerset Pharmaceuticals, Inc. S-(+)-desmethylselegiline and its use in the therapeutic methods and pharmaceutical compositions
US6348208B1 (en) * 1995-01-13 2002-02-19 Somerset Pharmaceuticals, Inc. Methods and pharmaceutical compositions employing desmethylselegiline
US6033682A (en) 1995-01-13 2000-03-07 Somerset Pharmaceuticals, Inc. S(+) desmethylselegiline and its use in therapeutic methods and pharmaceutical compositions
US6299901B1 (en) 1995-01-13 2001-10-09 Somerset Pharmaceuticals, Inc. Methods and pharmaceutical compositions employing desmethylselegiline
US5560913A (en) * 1995-01-27 1996-10-01 The Procter & Gamble Company Pharmaceutical compositions
US5567733B1 (en) * 1995-04-27 1999-08-24 Jon G Dishler Irritation relief using nonsteroidal anti-inflammatory compounds
CA2223588C (fr) * 1995-06-07 2004-01-06 Noven Pharmaceuticals, Inc. Compositions transdermiques contenant des medicaments de faible poids moleculaire liquides a temperature ambiante
US6316022B1 (en) 1995-06-07 2001-11-13 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
AU744913B2 (en) * 1995-07-06 2002-03-07 Smith & Nephew Plc Water activable adhesive matrix containing amethocaine
DE19524691A1 (de) * 1995-07-06 1997-01-09 Liedtke Pharmed Gmbh Methode und Zusammensetzung einer topischen Therapie von Innenohr und Labyrinth-Symptomen
GB9513742D0 (en) * 1995-07-06 1995-09-06 Smith & Nephew Compositions
DE19526031A1 (de) * 1995-07-17 1997-01-23 Liedtke Pharmed Gmbh Methode und Zusammensetzung einer topischen Therapie von Rückenschmerz und Muskelverspannung
GB9517062D0 (en) * 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
DE19546159A1 (de) * 1995-12-11 1997-06-12 Liedtke Pharmed Gmbh Methode und Zusammensetzung einer topisch wirksamen Therapie postoperativer und posttraumatischer Wundschmerzen
US5760102A (en) * 1996-02-20 1998-06-02 Carrington Laboratories, Inc. Uses of denture adhesive containing aloe extract
DE19646392A1 (de) 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht
US5942243A (en) * 1996-11-12 1999-08-24 Polytherapeutics, Inc. Mucoadhesive compositions for administration of biologically active agents to animal tissue
DE19701949A1 (de) * 1997-01-13 1998-07-16 Jenapharm Gmbh Transdermales therapeutisches System
US6117911A (en) 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
US6024981A (en) 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
US6312450B1 (en) 1997-05-20 2001-11-06 Natural Vision Center, Inc. System and method for improving the appearance of skin
US7150881B2 (en) 1997-06-26 2006-12-19 Mylan Technologies, Inc. Adhesive mixture for transdermal delivery of highly plasticizing drugs
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
US20040018241A1 (en) * 1997-09-26 2004-01-29 Noven Pharmaceuticals, Inc. Bioadhesive compositions and methods for topical administration of active agents
EP1021204B1 (fr) 1997-09-26 2005-12-28 Noven Pharmaceuticals, Inc. Compositions bioadhesives et methodes d'administration locale d'agents actifs
US6974590B2 (en) * 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
US20030091629A1 (en) * 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
US6174524B1 (en) 1999-03-26 2001-01-16 Alcon Laboratories, Inc. Gelling ophthalmic compositions containing xanthan gum
US6261547B1 (en) 1998-04-07 2001-07-17 Alcon Manufacturing, Ltd. Gelling ophthalmic compositions containing xanthan gum
EP1123696B1 (fr) * 1998-09-25 2006-05-24 Kao Corporation Compositions pour cavite buccale
ES2601855T3 (es) 1998-11-25 2017-02-16 Cima Labs Inc. Comprimido de liberación rápida con núcleo recubierto que contiene el fármaco y capa circundante de enmascaramiento del sabor
US6740341B1 (en) 1998-11-25 2004-05-25 Cima Labs Inc. Taste masking rapid release coating system
US6337086B1 (en) 1999-02-06 2002-01-08 Dow Corning Corporation Pressure sensitive adhesive compositions for transdermal drug delivery devices
US7063859B1 (en) 1999-04-28 2006-06-20 Noven Pharmaceuticals, Inc. Barrier film lined backing layer composition and method for topical administration of active agents
US6231957B1 (en) 1999-05-06 2001-05-15 Horst G. Zerbe Rapidly disintegrating flavor wafer for flavor enrichment
WO2000074661A2 (fr) * 1999-06-05 2000-12-14 Noven Pharmaceuticals, Inc. Amelioration de la solubilite de medicaments dans des systemes d'administration transdermique de medicaments et procedes d'utilisation
US6254594B1 (en) 1999-07-30 2001-07-03 Quadrivium, Llc Disposable light source for photothermal treatment of human tissue
US6264973B1 (en) 1999-08-26 2001-07-24 Fei Enterprises, Ltd. Apparatus and method for anesthetizing the cervical region of a female
US6648872B1 (en) * 1999-09-07 2003-11-18 Stephen M. Zappala Circumferential compression device for intracavernosal anesthesia and method for using same
PT1225898E (pt) 1999-11-01 2003-10-31 Alcon Inc Composicoes farmaceuticas contendo um farmaco antibiotico de fluoroquinolona e goma xantana
KR100403699B1 (ko) 2000-03-17 2003-11-01 주식회사 엘지생활건강 치아 미백용 패취
US7785572B2 (en) * 2000-03-17 2010-08-31 Lg Household And Health Care Ltd. Method and device for teeth whitening using a dry type adhesive
US8652446B2 (en) 2000-03-17 2014-02-18 Lg Household & Healthcare Ltd. Apparatus and method for whitening teeth
US6689344B2 (en) 2000-03-17 2004-02-10 Lg Household & Healthcare Ltd. Patches for teeth whitening
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
BR0112787B1 (pt) 2000-07-28 2013-03-05 composiÇço de soluÇço topicamente administrÁvel.
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US9056060B2 (en) * 2000-09-19 2015-06-16 Henkel Ag & Co. Kgaa Non-reactive adhesive useful in transdermal drug delivery system
EP1390084B1 (fr) 2001-05-01 2011-03-23 A.V. Topchiev Institute of Petrochemical Synthesis Composition bioadhesive biphase absorbant l'eau
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
ES2331302T3 (es) 2001-05-01 2009-12-29 A.V. Topchiev Institute Of Petrochemical Synthesis Composiciones de hidrogel.
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
CA2446060A1 (fr) * 2001-05-07 2002-11-14 Corium International Compositions et systemes d'administration d'un anesthesique local
US20030035839A1 (en) * 2001-05-15 2003-02-20 Peirce Management, Llc Pharmaceutical composition for both intraoral and oral administration
AU2011244985B2 (en) * 2001-06-18 2014-06-12 Jaleva, Llc Gum resin as a carrier for topical application of pharmacologically active agents
US6899897B2 (en) * 2001-06-18 2005-05-31 Jaleva, Inc. Gum resin as a carrier for topical application of pharmacologically active agents
US6660292B2 (en) 2001-06-19 2003-12-09 Hf Flavoring Technology Llp Rapidly disintegrating flavored film for precooked foods
US6946142B2 (en) 2001-06-23 2005-09-20 Lg Household & Healthcare Ltd. Multi-layer patches for teeth whitening
US8663687B2 (en) 2001-10-12 2014-03-04 Monosol Rx, Llc Film compositions for delivery of actives
US7357891B2 (en) * 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US7666337B2 (en) * 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US20100021526A1 (en) * 2001-10-12 2010-01-28 Monosol Rx, Llc Ph modulated films for delivery of actives
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US7425292B2 (en) * 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US20070154527A1 (en) * 2001-10-12 2007-07-05 Monosoirx, Llc Topical film compositions for delivery of actives
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US20060039958A1 (en) * 2003-05-28 2006-02-23 Monosolrx, Llc. Multi-layer films having uniform content
US20070281003A1 (en) * 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US8765167B2 (en) * 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US7910641B2 (en) * 2001-10-12 2011-03-22 Monosol Rx, Llc PH modulated films for delivery of actives
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US8425892B2 (en) * 2001-10-29 2013-04-23 Columbia Laboratories, Inc. Extended, controlled-release pharmaceutical compositions using charged polymers
US20030114394A1 (en) * 2001-10-29 2003-06-19 Levine Howard L. Vaginally administered anti-dysrhythmic agents for treating pelvic pain
US20080182841A1 (en) * 2001-10-29 2008-07-31 Levine Howard L Vaginally administered anti-dysrhythmic agents for treating pelvic pain
ATE487456T1 (de) * 2001-12-13 2010-11-15 Vital Health Sciences Pty Ltd Transdermaler transport von verbindungen
US8017150B2 (en) * 2002-04-11 2011-09-13 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
EP1542903B1 (fr) * 2002-07-22 2015-05-20 MonoSolRX, LLC Emballage et distribution d'une forme posologique a dissolution rapide
AU2002950713A0 (en) 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
ES2319764T3 (es) * 2002-11-26 2009-05-12 Endo Pharmaceuticals Inc. Composicion y su uso en el tratamiento de la perdida sensorial neuropatica.
BRPI0408454A (pt) 2003-03-21 2006-04-04 Nexmed Holdings Inc composição tópica, método de tratar a ejaculação precoce, e, uso da composição
CN1826099B (zh) * 2003-07-25 2010-06-09 凡林有限公司 固体剂型药物组合物及其制造方法
US20050074489A1 (en) * 2003-10-01 2005-04-07 Pediamed Pharmaceuticals, Inc. Effervescent and effervescent-dispersion compositions for medicaments and methods of use thereof
US9554984B2 (en) 2003-11-03 2017-01-31 Jaleva Pharmaceuticals, Llc Oral care compositions for topical application
US20050136112A1 (en) * 2003-12-19 2005-06-23 Pediamed Pharmaceuticals, Inc. Oral medicament delivery system
CN102078310B (zh) * 2003-12-31 2013-01-23 奇马实验室公司 大体线性的泡腾口服芬太尼剂型和施用方法
US7862833B2 (en) * 2003-12-31 2011-01-04 Cima Labs, Inc. Effervescent oral opiate dosage forms and methods of administering opiates
WO2005065317A2 (fr) * 2003-12-31 2005-07-21 Cima Labs Inc. Forme posologique orale effervescente a base de fentanyl et procedes permettant d'administrer du fentanyl
RU2380092C2 (ru) 2004-01-30 2010-01-27 Кориум Интернэшнл, Инк. Быстро растворяющаяся пленка для доставки активного агента
DK1758557T3 (da) 2004-05-11 2011-10-24 Egalet Ltd Kvældbar doseringsform omfattende gellangummi
US7666914B2 (en) * 2004-06-03 2010-02-23 Richlin David M Topical preparation and method for transdermal delivery and localization of therapeutic agents
CA2578709C (fr) * 2004-06-17 2010-06-15 Virun, Inc. Compositions comprenant une proteine adherant aux muqueuses et principe actif pour la delivrance d'agents dans des muqueuses
US20060004094A1 (en) * 2004-07-02 2006-01-05 Agisim Gary R Composition and method for treating hemorrhoids and/or anorectal disorders
EP1791575B1 (fr) 2004-08-05 2014-10-08 Corium International, Inc. Composition d'adhesif
US7718674B2 (en) * 2004-09-27 2010-05-18 Bridge Pharma, Inc. Methods of relieving neuropathic pain with the S-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine
WO2006037047A2 (fr) * 2004-09-27 2006-04-06 Bridge Pharma, Inc. R-isomere de 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine et autres agents anesthesiques dermiques
US8551979B2 (en) * 2004-11-05 2013-10-08 Lead Chemical Co., Ltd. Nonaqueous preparation for percutaneous absorption containing nonsteroidal anti-inflammatory analgesic
US20060147516A1 (en) * 2005-01-06 2006-07-06 Cima Labs Inc. Taste masking system for alprazolam
WO2006076553A2 (fr) * 2005-01-14 2006-07-20 Cima Labs Inc. Emballage de comprimé pelable et pliable
EP1836103B1 (fr) * 2005-01-14 2010-03-03 Cima Labs Inc. Conditionnement de medicament presentant une securite pour les enfants
US20060278558A1 (en) * 2005-01-14 2006-12-14 Michelle Nivala Non-tearable child resistant blister package
DE102005005573B4 (de) * 2005-02-07 2007-03-08 Lts Lohmann Therapie-Systeme Ag Hydrophiles Gelsystem zur Hautpflege auf Basis von Karaya-Gummi
US9168216B2 (en) 2005-06-17 2015-10-27 Vital Health Sciences Pty. Ltd. Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
US20070048373A1 (en) 2005-08-30 2007-03-01 Cima Labs Inc. Dried milled granulate and methods
US8623334B1 (en) 2005-09-29 2014-01-07 Alan J. Wickenhauser Topical anesthetic
US8263047B2 (en) * 2005-09-29 2012-09-11 Wickenhauser Alan J Topical anesthetic for dental procedures
EP1947934A4 (fr) 2005-11-07 2012-04-25 Jaleva Llc Résines de formation de film comme porteuses pour application locale d'agents pharmacologiquement actifs
EP1986601A2 (fr) * 2006-01-20 2008-11-05 MonoSol Rx LLC Sac revêtu d'un film ainsi que le procédé pour fabriquer ce sac
WO2007127158A2 (fr) * 2006-04-25 2007-11-08 Croda, Inc Modification d'absorption percutanée de matériaux topiquement actifs
WO2007130748A1 (fr) * 2006-05-03 2007-11-15 Discus Dental Impressions, Inc. instruments dentaires ayant un revetement anti-microbien
US8637076B2 (en) * 2006-06-01 2014-01-28 Cima Labs Inc. Prednisolone salt formulations
US20070281014A1 (en) * 2006-06-01 2007-12-06 Cima Labs, Inc. Prednisolone salt formulations
US20080069891A1 (en) 2006-09-15 2008-03-20 Cima Labs, Inc. Abuse resistant drug formulation
CA2655809C (fr) * 2006-07-21 2013-10-01 Bridge Pharma, Inc. Composes anesthesiques dermiques
US20080031944A1 (en) * 2006-08-04 2008-02-07 Cima Labs Inc. Stabilization of lorazepam
WO2008036299A2 (fr) * 2006-09-20 2008-03-27 Monosol Rx Llc Film hydrosoluble comestible contenant un agent aromatisant réduisant la mousse
EP2077824A4 (fr) * 2006-09-29 2012-07-18 Monosol Rx Llc Conditionnement dans lequel un film est incorporé et son procédé de fabrication
US8337883B2 (en) 2006-11-03 2012-12-25 Durect Corporation Transdermal delivery systems
BRPI0719428A2 (pt) * 2006-12-01 2014-02-25 Cima Labs Inc Forma de dosagem transmucosal oral sólida, método para tratar dependência de nicotina em um receptor que deseja tal tratamento, sistema de distribuição de nicotina transmucosal oral, e, método de substituíção de nicotina.
US20090214442A1 (en) * 2006-12-01 2009-08-27 Cephalon, Inc. Oral Transmucosal Nicotine Dosage Form
WO2008080146A1 (fr) * 2006-12-26 2008-07-03 Discus Dental, Llc Gratte langue jetable
WO2009035474A1 (fr) 2007-09-13 2009-03-19 Cima Labs Inc. Formulation médicamenteuse contre l'abus
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8119694B2 (en) 2008-08-15 2012-02-21 Arcion Therapeutics, Inc. High concentration local anesthetic formulations
ES2400210T3 (es) 2008-10-02 2013-04-08 Mylan Inc. Método para preparar un laminado de adhesivo multicapa
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
WO2010083035A2 (fr) 2009-01-14 2010-07-22 Corium International, Inc. Administration transdermique de tamsulosine
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
SI2440199T1 (sl) * 2009-06-11 2016-05-31 Photocure Asa Poltrdni sestavki in farmacevtski proizvodi
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
EP2506838A1 (fr) * 2009-12-01 2012-10-10 Noven Pharmaceuticals, INC. Dispositif d'administration transdermique de testostérone
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
US20110136815A1 (en) * 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
EP2531047B1 (fr) 2010-02-05 2024-11-13 Phosphagenics Limited Vecteur comprenant du phosphate de tocophéryle non neutralisé
ES2829386T3 (es) 2010-03-30 2021-05-31 Phosphagenics Ltd Parche de administración transdérmica
WO2011130455A1 (fr) * 2010-04-13 2011-10-20 Najib Babul Compositions pharmaceutiques dermiques de 1-méthyl-2',6'-pipécoloxylidide et méthode d'utilisation
ES2871021T3 (es) 2010-05-12 2021-10-28 Spectrum Pharmaceuticals Inc Hidróxido de carbonato de lantano, oxicarbonato de lantano y procedimientos de fabricación y uso
JP5819949B2 (ja) 2010-06-10 2015-11-24 ミダテック リミテッド ナノ粒子フィルム送達システム
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
WO2012064766A2 (fr) * 2010-11-09 2012-05-18 Jie Zhang Systèmes de combinaison d'un feuillet et d'un liquide destinés à administrer des médicaments par voie percutanée
WO2012122586A1 (fr) 2011-03-15 2012-09-20 Phosphagenics Limited Nouvelle composition
JP5856153B2 (ja) * 2011-05-10 2016-02-09 伊藤忠ケミカルフロンティア株式会社 非水性貼付剤
US11786455B2 (en) 2011-05-10 2023-10-17 Itochu Chemical Frontier Corporation Non-aqueous patch
ES3034911T3 (en) 2011-05-10 2025-08-26 Itochu Chemical Frontier Corp Non-aqueous patch
SI2823815T1 (sl) * 2011-09-27 2018-09-28 Itochu Chemical Frontier Corporation Ne-vodni obliž
AR092999A1 (es) 2012-10-15 2015-05-13 Noven Pharma Composiciones y metodos para la administracion transdermica de metilfenidato
WO2014106014A1 (fr) 2012-12-28 2014-07-03 Noven Pharmaceuticals, Inc Systèmes d'administration de médicament transdermique pour lévonorgestrel et éthinyl estradiol
AU2013370297A1 (en) 2012-12-28 2015-07-16 Noven Pharmaceuticals, Inc. Multi-polymer compositions for transdermal drug delivery
US11337936B2 (en) 2013-03-14 2022-05-24 Noven Pharmaceuticals, Inc. Amphetamine transdermal compositions with acrylic block copolymer
CA2903828A1 (fr) 2013-03-14 2014-10-02 Cephalon, Inc. Couvercle a l'epreuve des enfants pour formes dosifiees orales
AR095259A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones y métodos para la administración transdérmica de fármacos de amina terciaria
AR095260A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones de anfetaminas transdérmicas estables y métodos de fabricación
US9140513B2 (en) 2013-12-02 2015-09-22 PT Archery Compact compound bow
WO2015137872A1 (fr) * 2014-03-13 2015-09-17 Innovator Skåne Ab Système d'administration de médicament en forme de feuille ou tubulaire
US10406116B2 (en) 2015-02-06 2019-09-10 Noven Pharmaceuticals, Inc. Pressure-sensitive adhesives for transdermal drug delivery
EP3253840B1 (fr) 2015-02-06 2019-07-31 Noven Pharmaceuticals, INC. Adhésifs sensibles à la pression pour la livraison transdermique de médicaments
USD774154S1 (en) 2015-03-20 2016-12-13 P.T. Archery Llc Archery bow riser
JP6770339B2 (ja) * 2015-08-11 2020-10-14 株式会社コーセー ミコナゾール硝酸塩含有組成物
MX383940B (es) 2015-12-09 2025-03-14 Phosphagenics Ltd Formulación farmacéutica que contiene tocol fosfato.
US12427121B2 (en) 2016-05-05 2025-09-30 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
WO2017192921A1 (fr) 2016-05-05 2017-11-09 Monosol Rx, Llc Compositions d'épinéphrine à administration améliorée
US12433850B2 (en) 2016-05-05 2025-10-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine and prodrug compositions
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
IL267006B2 (en) 2016-12-21 2024-11-01 Phosphagenics Ltd Process for phosphorylation of a complex alcohol with p4o10 at high temperatures, and products thereof
US10527382B2 (en) 2017-04-19 2020-01-07 P.T. Archery Llc Non-planar riser plates
EP3703668A1 (fr) * 2017-11-01 2020-09-09 Clexio Biosciences Ltd. Structures fibreuses finies et leur procédés d'utilisation et de préparation
US11389844B2 (en) 2018-03-20 2022-07-19 Verde Environmental Technologies, Inc. Blister pack disposal system
GB2575625A (en) 2018-06-22 2020-01-22 Church & Dwight Co Inc Oral care compositions comprising benzocaine and mucoadhesive thin films formed therefrom
CN112789013A (zh) 2018-07-31 2021-05-11 斯尔替克美学股份有限公司 改善肤质的方法、装置和系统
US10966924B2 (en) 2018-09-04 2021-04-06 Babak Ghalili Veterinary cannabinoid, menthol and anesthetic compositions and methods
US20200069604A1 (en) * 2018-09-04 2020-03-05 Babak Ghalili Cannabinoid and anesthetic compositions and methods
US11185526B2 (en) 2018-09-04 2021-11-30 Babak Ghalili Cannabinoid, menthol and caffeine dissolvable film compositions, devices and methods
US10751299B2 (en) 2018-09-04 2020-08-25 Babak Ghalili Cannabinoid and menthol compositions and methods
US11147775B2 (en) 2018-09-04 2021-10-19 Babak Ghalili Cannabinoid and menthol gel compositions, patches and methods
ES2777899A1 (es) * 2019-02-06 2020-08-06 Hector Alfredo Duilio Polizzi Apósito oral con efecto anestésico
US12465564B2 (en) 2021-10-25 2025-11-11 Aquestive Therapeutics, Inc. Oral and nasal compositions and methods of treatment
WO2023230181A1 (fr) 2022-05-24 2023-11-30 Verde Environmental Technologies, Inc. Système d'élimination de formulation pharmaceutique indésirable

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2142537A (en) * 1936-07-22 1939-01-03 Rare Chemicals Inc Anesthetic ointment
US2277038A (en) * 1937-10-30 1942-03-24 Curtis David Anesthetic preparation
US2352691A (en) * 1941-07-25 1944-07-04 Curtis David Anesthetic compound and preparation
US2501544A (en) * 1946-10-23 1950-03-21 Shellmar Products Corp Therapeutic product
US3249109A (en) * 1963-11-01 1966-05-03 Maeth Harry Topical dressing
DE1617282A1 (de) * 1965-11-30 1975-02-06 Astra Pharma Prod Vorrichtung zur lokalanaesthetisierung durch oertliche aufbringung und verfahren zur herstellung dieser vorrichtung
SE352239B (fr) * 1966-11-30 1972-12-27 Astra Pharma Prod
US3632740A (en) * 1968-06-13 1972-01-04 Johnson & Johnson Topical device for the therapeutic management of dermatological lesions with steroids
US3640741A (en) * 1970-02-24 1972-02-08 Hollister Inc Composition containing gel
DE2057174A1 (de) * 1970-11-20 1972-05-25 Espe Pharm Praep Pharmazeutisches Produkt,insbesondere injizierbares Lokalanaesthetikum
US3814095A (en) * 1972-03-24 1974-06-04 H Lubens Occlusively applied anesthetic patch
US3972995A (en) * 1975-04-14 1976-08-03 American Home Products Corporation Dosage form
US4675009A (en) * 1977-11-07 1987-06-23 Lec Tec Corporation Drug dispensing device for transdermal delivery of medicaments
SE7713618L (sv) * 1977-12-01 1979-06-02 Astra Laekemedel Ab Lokalanestetisk blandning
SE431092B (sv) * 1979-07-10 1984-01-16 Thuresson Af Ekenstam Bo Terapeutiskt aktiva, substituerade piperidinkarboxianilider
US4307075A (en) * 1979-09-13 1981-12-22 American Home Products Corporation Topical treatment of aphthous stomatitis
CA1208558A (fr) * 1982-10-07 1986-07-29 Kazuo Kigasawa Medicament oral
US4608249A (en) * 1982-11-02 1986-08-26 Nitto Electric Industrial Co., Ltd. Hydrophilic therapeutic material
US4466973A (en) * 1983-02-01 1984-08-21 Thomas Rennie Method of treating nasal and sinus congestion
DD217989A1 (de) * 1983-08-09 1985-01-30 Univ Ernst Moritz Arndt Verfahren zur herstellung einer pharmazeutischen zubereitung
EP0139127A1 (fr) * 1983-08-22 1985-05-02 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Dispositif pour la délivrance transdermale de médicaments et sa fabrication
EP0163696B1 (fr) * 1983-11-14 1992-11-25 Columbia Laboratories, Inc. Application d'une bioadhesive
US4659714A (en) * 1984-03-27 1987-04-21 Dentsply, Ltd. Anesthetic methods for mammals
CA1248450A (fr) * 1984-04-05 1989-01-10 Kazuo Kigasawa Piece molle
JPS6160620A (ja) * 1984-09-03 1986-03-28 Teijin Ltd ピログルタミン酸エステル類を含有する医薬品組成物
JPS6164570A (ja) * 1984-09-04 1986-04-02 Akebono Brake Ind Co Ltd アンチスキツド制御方法
US4748022A (en) * 1985-03-25 1988-05-31 Busciglio John A Topical composition
JPS61280423A (ja) * 1985-06-05 1986-12-11 Kiyuukiyuu Yakuhin Kogyo Kk 口腔内粘膜貼付剤
GB8514665D0 (en) * 1985-06-11 1985-07-10 Eroceltique Sa Oral pharmaceutical composition
IL78826A (en) * 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
JPH0744940B2 (ja) * 1986-12-24 1995-05-17 ライオン株式会社 口腔貼付用基材
DE3714074A1 (de) * 1987-04-28 1988-11-10 Hoechst Ag Grundlage fuer schleimhaut- und prothesenhaft-pasten, verfahren zu ihrer herstellung sowie pasten auf basis dieser grundlage
US4867970A (en) * 1987-05-21 1989-09-19 E. R. Squibb & Sons, Inc. Moistureless oral drug delivery formulation and method for preparing same
DE3726797A1 (de) * 1987-08-12 1989-02-23 Bayer Ag Arzneimittel fuer den bereich der mundhoehle
US4888354A (en) * 1987-12-21 1989-12-19 Theratech, Inc. Skin penetration enhancement using free base and acid addition salt combinations of active agents
EP0331392A3 (fr) * 1988-03-01 1990-02-14 Alza Corporation Anésthésie et antisepsie de la peau
US4900552A (en) * 1988-03-30 1990-02-13 Watson Laboratories, Inc. Mucoadhesive buccal dosage forms
GB8810951D0 (en) * 1988-05-09 1988-06-15 Innovata Biomed Ltd Buccal local anaesthetic
US4937078A (en) * 1988-08-26 1990-06-26 Mezei Associates Limited Liposomal local anesthetic and analgesic products
JPH02196717A (ja) * 1988-10-07 1990-08-03 Block Drug Co Inc 歯根膜病の治療方法

Also Published As

Publication number Publication date
CA2104474C (fr) 2000-01-04
SG49158A1 (en) 1998-05-18
EP0728477A3 (fr) 1996-09-11
DK0573576T3 (da) 1997-04-01
ES2094906T3 (es) 1997-02-01
ATE144704T1 (de) 1996-11-15
AU2833195A (en) 1995-09-28
NO933296D0 (no) 1993-09-16
WO1992015289A1 (fr) 1992-09-17
JPH06508820A (ja) 1994-10-06
NO307363B1 (no) 2000-03-27
AU1461092A (en) 1992-10-06
NO933296L (no) 1993-11-01
AU694243B2 (en) 1998-07-16
CA2104474A1 (fr) 1992-08-28
US5234957A (en) 1993-08-10
ES2094906T5 (es) 2004-03-01
EP0728477A2 (fr) 1996-08-28
FI110161B (fi) 2002-12-13
DE69214938T2 (de) 1997-05-15
DE69214938D1 (de) 1996-12-05
FI933761A0 (fi) 1993-08-26
SG77626A1 (en) 2001-01-16
FI933761L (fi) 1993-08-26
EP0573576A1 (fr) 1993-12-15
DE69214938T3 (de) 2004-05-13
GR3022708T3 (en) 1997-05-31
AU658870B2 (en) 1995-05-04
EP0573576B1 (fr) 1996-10-30
EP0573576B2 (fr) 2003-07-09

Similar Documents

Publication Publication Date Title
DK0573576T4 (da) Midler til topisk administration af farmaceutisk aktive stoffer
WO1996040086A3 (fr) Compositions et methodes pour l'administration locale d'agents pharmaceutiquement actifs
DK1021204T3 (da) Bioadhæsive præparater og fremgangsmåder til topisk administration af aktive midler
ITRM910922A1 (it) Composizione farmaceutica anticefalalgica per somministrazione endonasale, procedimento per prepararla e suo impiego terapeutico
FI895681A7 (fi) Farmaseuttinen ainekoostumus systeemistä transdermaalista antoa varten
EE9700241A (et) Farmatseutiline kompositsioon transdermaalseks manustamiseks
BR9807009A (pt) Composição paa administração transferência de medicamentos esteróides
MX9101175A (es) Composicion farmaceutica para administracion nasal
NO981638L (no) Legemiddel- avgivelsesanordning for to eller flere aktive forbindelser
DK372786A (da) Farmaceutiske praeparater af phenindamin (2,3,4,9-tetrahydro-2-methyl-9-phenyl-1h-indeno(2,1-c)pyridin)
AR012376A1 (es) Formulacion de gel para la aplicacion topica
BR9708706B1 (pt) composiÇço farmacÊutica para administraÇço intravenosa a um paciente
DE69434121D1 (de) Pharmazeutische zusammensetzung zur immunstimulierenden therapie
EP0674511A1 (fr) Procedes et compositions antipyretiques et analgesiques contenant du r-cetrolac optiquement pur.
SE9002278D0 (sv) The use of inositoltrisphosphate for the preparing of medicaments
DE3587794D1 (de) Pharmazeutische Präparate.
FI970331L (fi) Lääkkeen antokoostumus virustenvastaisten aineiden nenään toteutettavaa antoa varten
AR012638A1 (es) Uso de pregnan-3-ol-20-onas para la manufactura de un medicamento util para proveer una terapia progestacional
DK0556051T3 (da) Anvendelse af bilobalid samt derivater deraf til behandling af en infektion hos et individ og farmaceutiske præparater tilpasset denne anvendelse.
AR010343A1 (es) Uso de 17 beta-dihidroequilenina o una sal farmaceuticamente aceptable del ester de 17 beta-dihidroequilenina-3-sulfato para la manufactura de unmedicamento como antioxidante y composicion farmaceutica.
SK66U (sk) Analgetický prostriedok s protizápalovým, antiseptickým a hojivým účinkom
ES2135424T3 (es) Composicion oral a base de ibuprofeno.
IT8819541A0 (it) Composizione farmaceutica per somministrazione nasale.