DK0602454T3 - N-oxycarbonylsubstituerede 5-deoxy-5-fluorcytidiner - Google Patents

N-oxycarbonylsubstituerede 5-deoxy-5-fluorcytidiner

Info

Publication number
DK0602454T3
DK0602454T3 DK93119349.4T DK93119349T DK0602454T3 DK 0602454 T3 DK0602454 T3 DK 0602454T3 DK 93119349 T DK93119349 T DK 93119349T DK 0602454 T3 DK0602454 T3 DK 0602454T3
Authority
DK
Denmark
Prior art keywords
radical
formula
deoxy
integer
protecting groups
Prior art date
Application number
DK93119349.4T
Other languages
Danish (da)
English (en)
Inventor
Nobuo Shimma
Motohiro Arasaki
Hideo Ishitsuka
Isami Kuruma
Masanori Miwa
Chikako Murasaki
Isao Umeda
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8210304&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0602454(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0602454T3 publication Critical patent/DK0602454T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicinal Preparation (AREA)
DK93119349.4T 1992-12-18 1993-12-01 N-oxycarbonylsubstituerede 5-deoxy-5-fluorcytidiner DK0602454T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92121538 1992-12-18

Publications (1)

Publication Number Publication Date
DK0602454T3 true DK0602454T3 (da) 1996-07-29

Family

ID=8210304

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93119349.4T DK0602454T3 (da) 1992-12-18 1993-12-01 N-oxycarbonylsubstituerede 5-deoxy-5-fluorcytidiner

Country Status (40)

Country Link
US (1) US5472949A (fr)
EP (1) EP0602454B1 (fr)
JP (1) JP2501297B2 (fr)
KR (1) KR100347218B1 (fr)
CN (1) CN1035617C (fr)
AT (1) ATE137244T1 (fr)
AU (1) AU671491B2 (fr)
BG (1) BG61485B1 (fr)
BR (1) BR9305089A (fr)
CA (1) CA2103324C (fr)
CZ (1) CZ284788B6 (fr)
DE (1) DE69302360T2 (fr)
DK (1) DK0602454T3 (fr)
EE (1) EE03086B1 (fr)
ES (1) ES2086856T3 (fr)
FI (1) FI112365B (fr)
GE (1) GEP20074251B (fr)
GR (1) GR3020286T3 (fr)
HR (1) HRP931430B1 (fr)
HU (2) HU218291B (fr)
IL (1) IL108000A0 (fr)
IS (1) IS4108A (fr)
LT (1) LT3115B (fr)
LV (1) LV10625B (fr)
MY (1) MY109282A (fr)
NO (1) NO300066B1 (fr)
NZ (1) NZ250414A (fr)
PH (1) PH30168A (fr)
PL (1) PL174100B1 (fr)
RO (1) RO112619B1 (fr)
RU (2) RU2493162C1 (fr)
SA (1) SA93140409B1 (fr)
SI (1) SI9300648B (fr)
SK (1) SK281403B6 (fr)
SV (1) SV1993000080A (fr)
TW (1) TW372239B (fr)
UA (1) UA39158C2 (fr)
UY (1) UY23697A1 (fr)
YU (1) YU49411B (fr)
ZA (1) ZA939293B (fr)

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US20100160442A1 (en) * 2006-07-18 2010-06-24 Ossovskaya Valeria S Formulations for cancer treatment
US20080085310A1 (en) * 2006-10-06 2008-04-10 Maria Oksana Bachynsky Capecitabine rapidly disintegrating tablets
CN100425617C (zh) * 2006-10-31 2008-10-15 浙江海正药业股份有限公司 一种含氟嘧啶类化合物烷氧羰酰化的方法
ITMI20070435A1 (it) 2007-03-05 2008-09-06 Innovate Biotechnology Srl 2',3'-di-o-acil-5-fluoronucleosidi
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Also Published As

Publication number Publication date
NO300066B1 (no) 1997-04-01
BG98304A (bg) 1994-01-03
FI112365B (fi) 2003-11-28
NO934671L (no) 1994-06-20
PL174100B1 (pl) 1998-06-30
DE69302360D1 (de) 1996-05-30
SV1993000080A (es) 1996-01-26
YU77993A (sh) 1996-10-18
FI935616L (fi) 1994-06-19
JPH06211891A (ja) 1994-08-02
HU218291B (en) 2000-07-28
HK1005875A1 (en) 1999-01-29
IS4108A (is) 1994-06-19
LV10625B (en) 1996-04-20
MY109282A (en) 1996-12-31
HU9303525D0 (en) 1994-04-28
CZ273193A3 (en) 1994-07-13
NZ250414A (en) 1995-12-21
RU2458932C2 (ru) 2012-08-20
FI935616A0 (fi) 1993-12-14
LT3115B (en) 1994-12-27
ZA939293B (en) 1994-06-18
HUT65757A (en) 1994-07-28
PH30168A (en) 1997-01-21
KR100347218B1 (ko) 2003-01-24
GEP20074251B (en) 2007-12-10
AU5069093A (en) 1994-06-30
CN1035617C (zh) 1997-08-13
EE03086B1 (et) 1998-04-15
CZ284788B6 (cs) 1999-03-17
TW372239B (en) 1999-10-21
BR9305089A (pt) 1994-07-05
CN1094056A (zh) 1994-10-26
JP2501297B2 (ja) 1996-05-29
HU211965A9 (en) 1996-01-29
EP0602454A1 (fr) 1994-06-22
ES2086856T3 (es) 1996-07-01
ATE137244T1 (de) 1996-05-15
AU671491B2 (en) 1996-08-29
EP0602454B1 (fr) 1996-04-24
HRP931430B1 (en) 1999-08-31
BG61485B1 (bg) 1997-09-30
RU2493162C1 (ru) 2013-09-20
LTIP1627A (en) 1994-07-15
KR940014428A (ko) 1994-07-18
IL108000A0 (en) 1994-04-12
DE69302360T2 (de) 1996-10-31
YU49411B (sh) 2006-01-16
CA2103324A1 (fr) 1994-06-19
SI9300648A (en) 1994-09-30
GR3020286T3 (en) 1996-09-30
CA2103324C (fr) 1997-12-23
LV10625A (lv) 1995-04-20
SK144493A3 (en) 1994-10-05
SA93140409B1 (ar) 2004-07-24
SK281403B6 (sk) 2001-03-12
RO112619B1 (ro) 1997-11-28
US5472949A (en) 1995-12-05
UY23697A1 (es) 1994-06-08
HRP931430A2 (en) 1998-06-30
RU2135511C1 (ru) 1999-08-27
UA39158C2 (uk) 2001-06-15
SI9300648B (sl) 2000-06-30
NO934671D0 (no) 1993-12-17
PL301541A1 (en) 1994-06-27

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