DK0624574T3 - Hidtil ukendte prostaglandinanaloger - Google Patents

Hidtil ukendte prostaglandinanaloger

Info

Publication number
DK0624574T3
DK0624574T3 DK94111337T DK94111337T DK0624574T3 DK 0624574 T3 DK0624574 T3 DK 0624574T3 DK 94111337 T DK94111337 T DK 94111337T DK 94111337 T DK94111337 T DK 94111337T DK 0624574 T3 DK0624574 T3 DK 0624574T3
Authority
DK
Denmark
Prior art keywords
hitherto unknown
prostaglandin analogues
prostaglandin
analogues
hitherto
Prior art date
Application number
DK94111337T
Other languages
Danish (da)
English (en)
Inventor
Toshihide C O Seikagak Inomata
Arata Yasuda
Yutaka Mizushima
Original Assignee
Seikagaku Kogyo Co Ltd
Yoshitomi Pharmaceutical
Asahi Glass Co Ltd
Yutaka Mizushima
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Kogyo Co Ltd, Yoshitomi Pharmaceutical, Asahi Glass Co Ltd, Yutaka Mizushima filed Critical Seikagaku Kogyo Co Ltd
Application granted granted Critical
Publication of DK0624574T3 publication Critical patent/DK0624574T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cosmetics (AREA)
DK94111337T 1989-10-16 1990-10-15 Hidtil ukendte prostaglandinanaloger DK0624574T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1266230A JP2602964B2 (ja) 1989-10-16 1989-10-16 プロスタグランジン類縁体およびその脂肪乳剤

Publications (1)

Publication Number Publication Date
DK0624574T3 true DK0624574T3 (da) 1999-10-25

Family

ID=17428079

Family Applications (2)

Application Number Title Priority Date Filing Date
DK94111337T DK0624574T3 (da) 1989-10-16 1990-10-15 Hidtil ukendte prostaglandinanaloger
DK90119772.3T DK0423697T3 (da) 1989-10-16 1990-10-15 Lipidemulsion indeholdende en prostaglandinanalog

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK90119772.3T DK0423697T3 (da) 1989-10-16 1990-10-15 Lipidemulsion indeholdende en prostaglandinanalog

Country Status (10)

Country Link
US (1) US5120870A (fr)
EP (2) EP0423697B1 (fr)
JP (1) JP2602964B2 (fr)
AT (2) ATE117989T1 (fr)
AU (1) AU641436B2 (fr)
CA (1) CA2027351C (fr)
DE (2) DE69033069T2 (fr)
DK (2) DK0624574T3 (fr)
ES (2) ES2070238T3 (fr)
GR (2) GR3015963T3 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2158350A1 (fr) * 1994-01-18 1995-07-20 Toru Minoshima 7-thiaprostaglandines et methode de production connexe
WO1999009992A1 (fr) * 1997-08-27 1999-03-04 Yoshitomi Pharmaceutical Industries, Ltd. Promoteurs de neovascularisation
DE69939826D1 (de) 1998-06-04 2008-12-11 Ltt Bio Pharma Co Ltd Verfahren zur herstellung eines gereinigten prostaglandin-derivats
US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
MXPA04002446A (es) 2001-09-26 2004-07-23 Baxter Int Preparacion de nanoparticulas de tamano de submicras mediante dispersion y remocion de la fase liquida o solvente.
JP2003342196A (ja) * 2002-05-31 2003-12-03 Mukku:Kk 静脈注射用組成物、その製造法およびその製剤
JP2007520555A (ja) * 2004-02-05 2007-07-26 バクスター・インターナショナル・インコーポレイテッド 自己安定化剤の使用により調製された分散剤
EP1655021B1 (fr) 2004-11-09 2008-10-29 Novagali Pharma SA Emulsion huile-dans-eau à basse concentration de l'agent cationique et au potentiel de zéta positif
CA2578176C (fr) * 2004-11-09 2013-09-24 Novagali Pharma Sa Emulsions ophtalmiques renfermant un agent immuno-suppressif
CN101282714B (zh) * 2005-10-10 2012-12-12 诺瓦加利制药公司 包含前列腺素的眼用乳剂
RU2470644C2 (ru) 2006-09-05 2012-12-27 Кью.Пи. КОПЭРЕЙШН Стабильная жировая эмульсия (варианты), способ ее получения, эмульгирующий агент и способы стабилизации простагландина и капель жира
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
EP2228058A1 (fr) 2009-03-04 2010-09-15 Novagali Pharma S.A. Émulsion anionique d'huile dans l'eau contenant des prostaglandines et leurs utilisations
EP2389939A1 (fr) 2010-05-28 2011-11-30 Novagali Pharma S.A. Utilisation de prostaglandines F2alpha et analogues pour la cicatrisation des lésions de la cornée et du conjonctif
WO2012021107A2 (fr) 2010-08-12 2012-02-16 Nanyang Technological University Formulation de liposomes pour l'administration d'un médicament dans l'œil
US9956195B2 (en) 2014-01-07 2018-05-01 Nanyang Technological University Stable liposomal formulations for ocular drug delivery

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4363817A (en) * 1981-08-27 1982-12-14 Miles Laboratories, Inc. Enol acylate analogs of E1 and E2 prostaglandins
JPS58222014A (ja) * 1982-06-18 1983-12-23 Taisho Pharmaceut Co Ltd プロスタグランジンe↓1脂肪乳剤
JPS59216820A (ja) * 1983-05-20 1984-12-06 Taisho Pharmaceut Co Ltd プロスタグランジン脂肪乳剤
JPH0818989B2 (ja) * 1984-01-12 1996-02-28 株式会社ミドリ十字 脂肪乳剤中のプロスタグランジンの安定化方法
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
JPS61151126A (ja) * 1984-12-25 1986-07-09 Teijin Ltd △7―プロスタグランジンa1類を有効成分として含有する注射用の脂肪乳剤

Also Published As

Publication number Publication date
ES2132279T3 (es) 1999-08-16
JP2602964B2 (ja) 1997-04-23
EP0624574A3 (fr) 1995-01-18
ES2070238T3 (es) 1995-06-01
ATE117989T1 (de) 1995-02-15
DE69016567D1 (de) 1995-03-16
AU6452690A (en) 1991-04-18
EP0423697A3 (en) 1992-08-05
JPH03204853A (ja) 1991-09-06
CA2027351A1 (fr) 1991-04-17
EP0624574B1 (fr) 1999-04-21
DK0423697T3 (da) 1995-05-29
AU641436B2 (en) 1993-09-23
EP0423697A2 (fr) 1991-04-24
US5120870A (en) 1992-06-09
GR3015963T3 (en) 1995-07-31
DE69016567T2 (de) 1995-09-21
ATE179169T1 (de) 1999-05-15
EP0423697B1 (fr) 1995-02-01
DE69033069T2 (de) 1999-08-19
CA2027351C (fr) 2001-06-19
EP0624574A2 (fr) 1994-11-17
GR3030718T3 (en) 1999-11-30
DE69033069D1 (de) 1999-05-27

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