DK0742438T3 - Screening af kombinationspeptidbiblioteker til udvælgelse af peptidligander til anvendelse ved affinitetsoprensning af målproteiner - Google Patents
Screening af kombinationspeptidbiblioteker til udvælgelse af peptidligander til anvendelse ved affinitetsoprensning af målproteinerInfo
- Publication number
- DK0742438T3 DK0742438T3 DK96106717T DK96106717T DK0742438T3 DK 0742438 T3 DK0742438 T3 DK 0742438T3 DK 96106717 T DK96106717 T DK 96106717T DK 96106717 T DK96106717 T DK 96106717T DK 0742438 T3 DK0742438 T3 DK 0742438T3
- Authority
- DK
- Denmark
- Prior art keywords
- peptide
- target protein
- target
- peptides
- support material
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Computational Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/438,331 US5834318A (en) | 1995-05-10 | 1995-05-10 | Screening of combinatorial peptide libraries for selection of peptide ligand useful in affinity purification of target proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0742438T3 true DK0742438T3 (da) | 2007-10-29 |
Family
ID=23740236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96106717T DK0742438T3 (da) | 1995-05-10 | 1996-04-29 | Screening af kombinationspeptidbiblioteker til udvælgelse af peptidligander til anvendelse ved affinitetsoprensning af målproteiner |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5834318A (da) |
| EP (1) | EP0742438B1 (da) |
| JP (1) | JPH09101306A (da) |
| AT (1) | ATE365325T1 (da) |
| AU (1) | AU716309B2 (da) |
| CA (1) | CA2175868A1 (da) |
| DE (1) | DE69637136T2 (da) |
| DK (1) | DK0742438T3 (da) |
| ES (1) | ES2289746T3 (da) |
| PT (1) | PT742438E (da) |
Families Citing this family (80)
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| WO1998011437A1 (en) | 1996-09-16 | 1998-03-19 | Conjuchem, Inc. | Affinity labeling libraries with tagged leaving groups |
| GB9800378D0 (en) * | 1998-01-08 | 1998-03-04 | Univ Liverpool | Proteome analysis |
| US6287874B1 (en) | 1998-02-02 | 2001-09-11 | Signature Bioscience, Inc. | Methods for analyzing protein binding events |
| US6720190B1 (en) | 1998-03-27 | 2004-04-13 | Ole Hindsgaul | Methods for screening compound libraries |
| US6613575B1 (en) | 1998-03-27 | 2003-09-02 | Ole Hindsgaul | Methods for screening compound libraries |
| CA2240325A1 (en) | 1998-03-27 | 1998-11-14 | Synsorb Biotech, Inc. | Methods for screening compound libraries |
| US6054047A (en) | 1998-03-27 | 2000-04-25 | Synsorb Biotech, Inc. | Apparatus for screening compound libraries |
| US6261848B1 (en) * | 1998-05-08 | 2001-07-17 | The Johns Hopkins University | Miniature immuno-optical rapid analyte sensor platform |
| US6908770B1 (en) | 1998-07-16 | 2005-06-21 | Board Of Regents, The University Of Texas System | Fluid based analysis of multiple analytes by a sensor array |
| US5994310A (en) * | 1998-09-03 | 1999-11-30 | Bayer Corporation | Peptide ligands for affinity purification of human Factor VIII |
| JP2002540384A (ja) * | 1999-02-11 | 2002-11-26 | ゼンコー | 構造ベースでの薬効物質スクリーニング法 |
| US6864359B1 (en) | 1999-02-11 | 2005-03-08 | Xencor | Structure-based screening techniques for drug discovery |
| EP1169641B1 (en) * | 1999-04-15 | 2007-10-17 | The University Of Virginia Patent Foundation | Proteome mining |
| AU1325201A (en) | 1999-07-16 | 2001-02-05 | Board Of Regents, The University Of Texas System | Detection system based on an analyte reactive particle |
| US7022517B1 (en) | 1999-07-16 | 2006-04-04 | Board Of Regents, The University Of Texas System | Method and apparatus for the delivery of samples to a chemical sensor array |
| DE19943743C2 (de) * | 1999-09-03 | 2002-02-07 | Jerini Biotools Gmbh | Verfahren zur Identifizierung von Bindungspartnern mit positions-spezifischen Arrays |
| AU4309201A (en) * | 1999-12-02 | 2001-06-12 | V.I. Technologies, Inc. | Method of identifying a ligand for a target molecule |
| ATE403145T1 (de) | 2000-01-31 | 2008-08-15 | Univ Texas | Tragbare vorrichtung mit einer sensor-array- anordnung |
| US6365355B1 (en) | 2000-03-28 | 2002-04-02 | The Regents Of The University Of California | Chimeric proteins for detection and quantitation of DNA mutations, DNA sequence variations, DNA damage and DNA mismatches |
| EP1272509A2 (en) * | 2000-04-05 | 2003-01-08 | V.I. Technologies, Inc. | Prion-binding peptidic ligands and methods of using same |
| EP1326892A2 (en) | 2000-10-12 | 2003-07-16 | University of Rochester | Compositions that inhibit proliferation of cancer cells |
| JP2004534519A (ja) * | 2000-11-17 | 2004-11-18 | アルフレッド イー. スランツ | 標的分子機能の決定と薬物リード化合物の同定に関する方法 |
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| WO2002072790A2 (en) | 2001-03-14 | 2002-09-19 | Myriad Genetics, Inc | Tsg101-gag interaction and use thereof |
| WO2003062831A1 (en) * | 2002-01-24 | 2003-07-31 | The Regents Of The University Of California | Method for determining differences in molecular interactions and for screening a combinatorial library |
| US7291456B2 (en) | 2002-01-24 | 2007-11-06 | The Regents Of The University Of California | Method for determining differences in molecular interactions and for screening a combinatorial library |
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| AU2003231731A1 (en) | 2002-04-15 | 2003-11-03 | American National Red Cross | Method for detecting ligands and targets in a mixture |
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| US8257967B2 (en) | 2002-04-26 | 2012-09-04 | Board Of Regents, The University Of Texas System | Method and system for the detection of cardiac risk factors |
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| EP1575992A4 (en) | 2002-08-05 | 2007-02-21 | Univ Rochester | CHEMICAL PROTEINS FROM PROTEIN TRANSDUCATING DOMAIN / DEAMINASE, RELATED COMPOUNDS AND THEIR USES |
| PT1953551E (pt) * | 2002-12-03 | 2014-05-06 | Pathogen Removal & Diagnostic Technologies Inc | Ligandos a proteína de prião e métodos de uso |
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| PT1615992E (pt) | 2003-04-04 | 2013-11-29 | Pathogen Removal & Diagnostic Technologies Inc | Materiais de ligação à proteína prião e métodos de utilização |
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| WO2004097371A2 (en) * | 2003-04-25 | 2004-11-11 | Board Of Regents, The University Of Texas System | System and method for the detection of analytes |
| US9317922B2 (en) | 2003-05-16 | 2016-04-19 | Board Of Regents The University Of Texas System | Image and part recognition technology |
| WO2004104922A2 (en) * | 2003-05-16 | 2004-12-02 | Board Of Regents, The University Of Texas System | Image and part recognition technology |
| US20050059083A1 (en) * | 2003-09-15 | 2005-03-17 | Becton Dickinson And Company | High throughput method to identify ligands for cell attachment |
| US8105849B2 (en) | 2004-02-27 | 2012-01-31 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements |
| US8101431B2 (en) | 2004-02-27 | 2012-01-24 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems |
| GB0416699D0 (en) * | 2004-07-27 | 2004-09-01 | Prometic Biosciences Ltd | Prion protein ligands and methods of use |
| US7408030B2 (en) * | 2005-01-13 | 2008-08-05 | North Carolina State University | Purification of immunoglobulins using affinity chromatography and peptide ligands |
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| US8076090B2 (en) | 2005-04-05 | 2011-12-13 | Corning Incorporated | Label free biosensors and cells |
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| EP2392645A1 (en) | 2005-10-14 | 2011-12-07 | MUSC Foundation For Research Development | Targeting PAX2 for the induction of DEFB1-mediated tumor immunity and cancer therapy |
| EP2560001B1 (en) | 2006-09-21 | 2016-04-13 | University of Rochester | Compositions and methods related to protein displacement therapy for myotonic distrophy |
| US8999317B2 (en) | 2006-11-01 | 2015-04-07 | University Of Rochester | Methods and compositions related to the structure and function of APOBEC3G |
| WO2008085116A1 (en) * | 2007-01-10 | 2008-07-17 | Ge Healthcare Bio-Sciences Ab | Mult i -modal ion exchange chromotography resins |
| WO2008098182A1 (en) | 2007-02-08 | 2008-08-14 | University Of Utah Research Foundation | Methods and compositions related to inhibition of viral entry |
| WO2010019963A2 (en) | 2008-08-15 | 2010-02-18 | Georgetown University | Na channels, disease, and related assays and compositions |
| US20120070443A1 (en) | 2008-12-02 | 2012-03-22 | University Of Utah Research Foundation | Pde1 as a target therapeutic in heart disease |
| KR101183159B1 (ko) * | 2008-12-22 | 2012-09-17 | 한국전자통신연구원 | 바이오 칩 및 이를 이용한 바이오 물질 검출 장치 |
| WO2011022502A1 (en) | 2009-08-18 | 2011-02-24 | Georgetown University | Boronic acid compositions and methods related to cancer |
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| US20130224730A1 (en) * | 2009-11-18 | 2013-08-29 | Arizona Board Of Regents Acting For And On Behalf Of Arizona State University | Peptide ligands |
| CA2784145A1 (en) | 2009-12-18 | 2011-06-23 | Sanford-Burnham Medical Research Institute | Methods and compositions related to clot-binding compounds |
| NZ609567A (en) | 2010-11-05 | 2015-05-29 | Transbio Ltd | Markers of endothelial progenitor cells and uses thereof |
| JP6153921B2 (ja) * | 2011-03-24 | 2017-06-28 | オプコ ファーマシューティカルズ、エルエルシー | ビーズまたは粒子ベースのライブラリーを用いた液体生体試料中でのバイオマーカー発見、並びに診断キットおよび治療法 |
| CA2868735C (en) | 2011-03-28 | 2020-02-25 | University Of Utah Research Foundation | D-peptide conjugates comprising a membrane localizing potency-enhancing cargo molecule for inhibiting hiv entry |
| WO2013172954A1 (en) | 2012-05-17 | 2013-11-21 | Ra Pharmaceuticals, Inc | Peptide and peptidomimetic inhibitors |
| CN103513039B (zh) * | 2013-07-10 | 2015-12-23 | 广州美格生物科技有限公司 | 一种利用定向肽库检测蛋白质与其他分子相互作用的方法 |
| EP3973994A1 (en) | 2014-06-12 | 2022-03-30 | RA Pharmaceuticals, Inc. | Modulation of complement activity |
| US9937222B2 (en) | 2015-01-28 | 2018-04-10 | Ra Pharmaceuticals, Inc. | Modulators of complement activity |
| AU2016361462B2 (en) | 2015-11-27 | 2023-09-21 | Csl Limited | CD131 binding proteins and uses thereof |
| RU2733720C2 (ru) | 2015-12-16 | 2020-10-06 | Ра Фармасьютикалз, Инк. | Модуляторы активности комплемента |
| KR20190093196A (ko) | 2016-12-07 | 2019-08-08 | 라 파마슈티컬스 인코포레이티드 | 보체 활성의 조절인자 |
| US12025615B2 (en) | 2017-09-15 | 2024-07-02 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods of classifying response to immunotherapy for cancer |
| JP2022535411A (ja) | 2019-06-04 | 2022-08-08 | ラ ファーマシューティカルズ インコーポレイテッド | 補体阻害剤による炎症性疾患治療 |
| WO2021067550A1 (en) | 2019-10-02 | 2021-04-08 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods and compositions for identifying neoantigens for use in treating and preventing cancer |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5133866A (en) * | 1988-03-24 | 1992-07-28 | Terrapin Technologies, Inc. | Method to identify analyte-bending ligands |
| US5650489A (en) * | 1990-07-02 | 1997-07-22 | The Arizona Board Of Regents | Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof |
| EP0473065A3 (en) * | 1990-08-29 | 1992-08-26 | Abbott Laboratories | Simultaneous assay for detecting two or more analytes |
-
1995
- 1995-05-10 US US08/438,331 patent/US5834318A/en not_active Expired - Lifetime
-
1996
- 1996-04-29 PT PT96106717T patent/PT742438E/pt unknown
- 1996-04-29 ES ES96106717T patent/ES2289746T3/es not_active Expired - Lifetime
- 1996-04-29 DK DK96106717T patent/DK0742438T3/da active
- 1996-04-29 AT AT96106717T patent/ATE365325T1/de active
- 1996-04-29 DE DE69637136T patent/DE69637136T2/de not_active Expired - Lifetime
- 1996-04-29 EP EP96106717A patent/EP0742438B1/en not_active Expired - Lifetime
- 1996-05-06 AU AU52087/96A patent/AU716309B2/en not_active Ceased
- 1996-05-06 CA CA002175868A patent/CA2175868A1/en not_active Abandoned
- 1996-05-07 JP JP8135710A patent/JPH09101306A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ATE365325T1 (de) | 2007-07-15 |
| CA2175868A1 (en) | 1996-11-11 |
| DE69637136D1 (de) | 2007-08-02 |
| EP0742438A2 (en) | 1996-11-13 |
| EP0742438B1 (en) | 2007-06-20 |
| AU716309B2 (en) | 2000-02-24 |
| AU5208796A (en) | 1996-11-21 |
| JPH09101306A (ja) | 1997-04-15 |
| US5834318A (en) | 1998-11-10 |
| EP0742438A3 (en) | 1998-04-08 |
| PT742438E (pt) | 2007-09-21 |
| DE69637136T2 (de) | 2008-02-21 |
| ES2289746T3 (es) | 2008-02-01 |
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