DK0768307T3 - Heterocykliske tertiære aminer, fremgangsmåde til fremstillling af disse og farmaceutiske sammensætninger indeholdende dem - Google Patents

Heterocykliske tertiære aminer, fremgangsmåde til fremstillling af disse og farmaceutiske sammensætninger indeholdende dem

Info

Publication number
DK0768307T3
DK0768307T3 DK96402148T DK96402148T DK0768307T3 DK 0768307 T3 DK0768307 T3 DK 0768307T3 DK 96402148 T DK96402148 T DK 96402148T DK 96402148 T DK96402148 T DK 96402148T DK 0768307 T3 DK0768307 T3 DK 0768307T3
Authority
DK
Denmark
Prior art keywords
alkyl
processes
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
DK96402148T
Other languages
Danish (da)
English (en)
Inventor
Jean-Louis Peglion
Bertrand Goument
Jean-Christophe Harmange
Joel Vian
Aimee Dessinges
Mark Millan
Valerie Audinot
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Application granted granted Critical
Publication of DK0768307T3 publication Critical patent/DK0768307T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/92Naphthopyrans; Hydrogenated naphthopyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/74Naphthothiophenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
DK96402148T 1995-10-13 1996-10-10 Heterocykliske tertiære aminer, fremgangsmåde til fremstillling af disse og farmaceutiske sammensætninger indeholdende dem DK0768307T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9512044A FR2739855B1 (fr) 1995-10-13 1995-10-13 Nouvelles amines heterocycliques tertiaires, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
DK0768307T3 true DK0768307T3 (da) 2004-04-05

Family

ID=9483510

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96402148T DK0768307T3 (da) 1995-10-13 1996-10-10 Heterocykliske tertiære aminer, fremgangsmåde til fremstillling af disse og farmaceutiske sammensætninger indeholdende dem

Country Status (15)

Country Link
US (1) US5726208A (de)
EP (1) EP0768307B1 (de)
JP (1) JPH09110858A (de)
CN (1) CN1150183C (de)
AT (1) ATE255100T1 (de)
AU (1) AU706831B2 (de)
CA (1) CA2187591C (de)
DE (1) DE69630854T2 (de)
DK (1) DK0768307T3 (de)
ES (1) ES2211941T3 (de)
FR (1) FR2739855B1 (de)
NO (1) NO314582B1 (de)
NZ (1) NZ299560A (de)
PT (1) PT768307E (de)
ZA (1) ZA968614B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3187217A1 (en) * 2020-08-06 2022-02-10 Matthew BAGGOTT 2-aminoindane compounds for mental disorders or enhancement

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4062840A (en) * 1973-05-02 1977-12-13 Akzona Incorporated Amino-substituted 1,2,3,4-tetrahydro-9H-tribenzo[b,d,f]azepines
FR2344284A1 (fr) * 1976-03-17 1977-10-14 Cerm Cent Europ Rech Mauvernay Nouveaux composes tricycliques a cycle furannique et leur application comme antidepresseurs
DE2803984A1 (de) * 1977-02-08 1978-08-10 Sandoz Ag Oxaminsaeurederivate, ihre herstellung und verwendung
US4470990A (en) * 1983-03-14 1984-09-11 Ayerst, Mckenna & Harrison Inc. 6,7,8,9-Tetrahydronaphtho(1,2-B)furan-8-amine derivatives and their use as dopamine receptor stimulants
FR2613365B1 (fr) * 1987-04-01 1989-07-28 Adir Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
EP0332246A1 (de) * 1988-03-11 1989-09-13 Akzo N.V. Trizyklische Amin-Derivate
EP0389425B1 (de) * 1989-03-22 1995-04-26 Ciba-Geigy Ag Neue Benzothiopyranylamine
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
FR2656606B1 (fr) * 1989-12-28 1993-06-25 Roussel Uclaf Utilisation de derives du 9,10-dihydrophenanthrene pour la preparation d'un medicament anti-tumoral, application a titre de medicaments de derives du 9,10-dihydrophenanthrene et produits derives de cette structure.
JPH059179A (ja) * 1990-09-27 1993-01-19 Takeda Chem Ind Ltd 複素環化合物、その製造法及びacat阻害剤
US5141960A (en) * 1991-06-25 1992-08-25 G. D. Searle & Co. Tricyclic glycinamide derivatives as anti-convulsants
US5538986A (en) * 1993-12-06 1996-07-23 Schering Corporation Tricyclic derivatives, compositions and methods of use

Also Published As

Publication number Publication date
US5726208A (en) 1998-03-10
FR2739855A1 (fr) 1997-04-18
AU6816896A (en) 1997-04-17
ATE255100T1 (de) 2003-12-15
DE69630854T2 (de) 2004-08-26
CN1150183C (zh) 2004-05-19
NO964336L (no) 1997-04-14
AU706831B2 (en) 1999-06-24
CA2187591C (fr) 2001-08-14
NO964336D0 (no) 1996-10-11
CN1152572A (zh) 1997-06-25
ZA968614B (en) 1997-05-13
NZ299560A (en) 1997-06-24
ES2211941T3 (es) 2004-07-16
NO314582B1 (no) 2003-04-14
EP0768307B1 (de) 2003-11-26
EP0768307A1 (de) 1997-04-16
PT768307E (pt) 2004-03-31
CA2187591A1 (fr) 1997-04-14
FR2739855B1 (fr) 1997-11-14
DE69630854D1 (de) 2004-01-08
JPH09110858A (ja) 1997-04-28

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