ATE255100T1 - Heterocyclisch tertiär amine, verfahren zu deren herstellung und diese enthaltende pharmazeutischen zusammenstellungen - Google Patents
Heterocyclisch tertiär amine, verfahren zu deren herstellung und diese enthaltende pharmazeutischen zusammenstellungenInfo
- Publication number
- ATE255100T1 ATE255100T1 AT96402148T AT96402148T ATE255100T1 AT E255100 T1 ATE255100 T1 AT E255100T1 AT 96402148 T AT96402148 T AT 96402148T AT 96402148 T AT96402148 T AT 96402148T AT E255100 T1 ATE255100 T1 AT E255100T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- production
- pharmaceutical compositions
- compositions containing
- tertiary amine
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003512 tertiary amines Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- -1 2-oxo-indolinyl Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000001475 halogen functional group Chemical group 0.000 abstract 3
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- UKJLNMAFNRKWGR-UHFFFAOYSA-N cyclohexatrienamine Chemical group NC1=CC=C=C[CH]1 UKJLNMAFNRKWGR-UHFFFAOYSA-N 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/74—Naphthothiophenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9512044A FR2739855B1 (fr) | 1995-10-13 | 1995-10-13 | Nouvelles amines heterocycliques tertiaires, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE255100T1 true ATE255100T1 (de) | 2003-12-15 |
Family
ID=9483510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96402148T ATE255100T1 (de) | 1995-10-13 | 1996-10-10 | Heterocyclisch tertiär amine, verfahren zu deren herstellung und diese enthaltende pharmazeutischen zusammenstellungen |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5726208A (de) |
| EP (1) | EP0768307B1 (de) |
| JP (1) | JPH09110858A (de) |
| CN (1) | CN1150183C (de) |
| AT (1) | ATE255100T1 (de) |
| AU (1) | AU706831B2 (de) |
| CA (1) | CA2187591C (de) |
| DE (1) | DE69630854T2 (de) |
| DK (1) | DK0768307T3 (de) |
| ES (1) | ES2211941T3 (de) |
| FR (1) | FR2739855B1 (de) |
| NO (1) | NO314582B1 (de) |
| NZ (1) | NZ299560A (de) |
| PT (1) | PT768307E (de) |
| ZA (1) | ZA968614B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3187217A1 (en) * | 2020-08-06 | 2022-02-10 | Matthew BAGGOTT | 2-aminoindane compounds for mental disorders or enhancement |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4062840A (en) * | 1973-05-02 | 1977-12-13 | Akzona Incorporated | Amino-substituted 1,2,3,4-tetrahydro-9H-tribenzo[b,d,f]azepines |
| FR2344284A1 (fr) * | 1976-03-17 | 1977-10-14 | Cerm Cent Europ Rech Mauvernay | Nouveaux composes tricycliques a cycle furannique et leur application comme antidepresseurs |
| SE7801074L (sv) * | 1977-02-08 | 1978-08-09 | Sandoz Ag | Organiska foreningar, deras framstellning och anvendning |
| US4470990A (en) * | 1983-03-14 | 1984-09-11 | Ayerst, Mckenna & Harrison Inc. | 6,7,8,9-Tetrahydronaphtho(1,2-B)furan-8-amine derivatives and their use as dopamine receptor stimulants |
| FR2613365B1 (fr) * | 1987-04-01 | 1989-07-28 | Adir | Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| EP0332246A1 (de) * | 1988-03-11 | 1989-09-13 | Akzo N.V. | Trizyklische Amin-Derivate |
| DK0389425T3 (da) * | 1989-03-22 | 1995-05-22 | Ciba Geigy Ag | Benzothiopyranylaminer |
| US5180736A (en) * | 1989-03-23 | 1993-01-19 | Warner-Lambert Company | Polycyclic amines useful as cerebrovascular agents |
| FR2656606B1 (fr) * | 1989-12-28 | 1993-06-25 | Roussel Uclaf | Utilisation de derives du 9,10-dihydrophenanthrene pour la preparation d'un medicament anti-tumoral, application a titre de medicaments de derives du 9,10-dihydrophenanthrene et produits derives de cette structure. |
| JPH059179A (ja) * | 1990-09-27 | 1993-01-19 | Takeda Chem Ind Ltd | 複素環化合物、その製造法及びａｃａｔ阻害剤 |
| US5141960A (en) * | 1991-06-25 | 1992-08-25 | G. D. Searle & Co. | Tricyclic glycinamide derivatives as anti-convulsants |
| US5538986A (en) * | 1993-12-06 | 1996-07-23 | Schering Corporation | Tricyclic derivatives, compositions and methods of use |
-
1995
- 1995-10-13 FR FR9512044A patent/FR2739855B1/fr not_active Expired - Fee Related
-
1996
- 1996-10-10 PT PT96402148T patent/PT768307E/pt unknown
- 1996-10-10 AT AT96402148T patent/ATE255100T1/de not_active IP Right Cessation
- 1996-10-10 EP EP96402148A patent/EP0768307B1/de not_active Expired - Lifetime
- 1996-10-10 CA CA002187591A patent/CA2187591C/fr not_active Expired - Fee Related
- 1996-10-10 DK DK96402148T patent/DK0768307T3/da active
- 1996-10-10 ES ES96402148T patent/ES2211941T3/es not_active Expired - Lifetime
- 1996-10-10 DE DE69630854T patent/DE69630854T2/de not_active Expired - Fee Related
- 1996-10-11 US US08/728,759 patent/US5726208A/en not_active Expired - Fee Related
- 1996-10-11 NZ NZ299560A patent/NZ299560A/en unknown
- 1996-10-11 AU AU68168/96A patent/AU706831B2/en not_active Ceased
- 1996-10-11 ZA ZA968614A patent/ZA968614B/xx unknown
- 1996-10-11 NO NO19964336A patent/NO314582B1/no not_active IP Right Cessation
- 1996-10-11 CN CNB961192801A patent/CN1150183C/zh not_active Expired - Fee Related
- 1996-10-14 JP JP8270483A patent/JPH09110858A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NZ299560A (en) | 1997-06-24 |
| DE69630854D1 (de) | 2004-01-08 |
| DK0768307T3 (da) | 2004-04-05 |
| NO964336L (no) | 1997-04-14 |
| JPH09110858A (ja) | 1997-04-28 |
| DE69630854T2 (de) | 2004-08-26 |
| ES2211941T3 (es) | 2004-07-16 |
| EP0768307B1 (de) | 2003-11-26 |
| CN1152572A (zh) | 1997-06-25 |
| NO964336D0 (no) | 1996-10-11 |
| FR2739855B1 (fr) | 1997-11-14 |
| PT768307E (pt) | 2004-03-31 |
| EP0768307A1 (de) | 1997-04-16 |
| CN1150183C (zh) | 2004-05-19 |
| NO314582B1 (no) | 2003-04-14 |
| FR2739855A1 (fr) | 1997-04-18 |
| US5726208A (en) | 1998-03-10 |
| AU6816896A (en) | 1997-04-17 |
| CA2187591C (fr) | 2001-08-14 |
| CA2187591A1 (fr) | 1997-04-14 |
| ZA968614B (en) | 1997-05-13 |
| AU706831B2 (en) | 1999-06-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0768307 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |