NO314582B1 - Nye heterocykliske terti¶re aminer, fremgangsmåte ved deres fremstilling ogfarmasöytiske sammensetninger inneholdende dem - Google Patents

Nye heterocykliske terti¶re aminer, fremgangsmåte ved deres fremstilling ogfarmasöytiske sammensetninger inneholdende dem Download PDF

Info

Publication number
NO314582B1
NO314582B1 NO19964336A NO964336A NO314582B1 NO 314582 B1 NO314582 B1 NO 314582B1 NO 19964336 A NO19964336 A NO 19964336A NO 964336 A NO964336 A NO 964336A NO 314582 B1 NO314582 B1 NO 314582B1
Authority
NO
Norway
Prior art keywords
formula
defined above
compounds
compound
hydrochloride
Prior art date
Application number
NO19964336A
Other languages
English (en)
Norwegian (no)
Other versions
NO964336L (no
NO964336D0 (no
Inventor
Jean-Louis Peglion
Bertrand Goument
Jean-Christophe Harmange
Joel Vian
Aimee Dessinges
Mark Millan
Valerie Audinot
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of NO964336D0 publication Critical patent/NO964336D0/no
Publication of NO964336L publication Critical patent/NO964336L/no
Publication of NO314582B1 publication Critical patent/NO314582B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/74—Naphthothiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO19964336A 1995-10-13 1996-10-11 Nye heterocykliske terti¶re aminer, fremgangsmåte ved deres fremstilling ogfarmasöytiske sammensetninger inneholdende dem NO314582B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9512044A FR2739855B1 (fr) 1995-10-13 1995-10-13 Nouvelles amines heterocycliques tertiaires, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (3)

Publication Number Publication Date
NO964336D0 NO964336D0 (no) 1996-10-11
NO964336L NO964336L (no) 1997-04-14
NO314582B1 true NO314582B1 (no) 2003-04-14

Family

ID=9483510

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19964336A NO314582B1 (no) 1995-10-13 1996-10-11 Nye heterocykliske terti¶re aminer, fremgangsmåte ved deres fremstilling ogfarmasöytiske sammensetninger inneholdende dem

Country Status (15)

Country Link
US (1) US5726208A (de)
EP (1) EP0768307B1 (de)
JP (1) JPH09110858A (de)
CN (1) CN1150183C (de)
AT (1) ATE255100T1 (de)
AU (1) AU706831B2 (de)
CA (1) CA2187591C (de)
DE (1) DE69630854T2 (de)
DK (1) DK0768307T3 (de)
ES (1) ES2211941T3 (de)
FR (1) FR2739855B1 (de)
NO (1) NO314582B1 (de)
NZ (1) NZ299560A (de)
PT (1) PT768307E (de)
ZA (1) ZA968614B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3187217A1 (en) * 2020-08-06 2022-02-10 Matthew BAGGOTT 2-aminoindane compounds for mental disorders or enhancement

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4062840A (en) * 1973-05-02 1977-12-13 Akzona Incorporated Amino-substituted 1,2,3,4-tetrahydro-9H-tribenzo[b,d,f]azepines
FR2344284A1 (fr) * 1976-03-17 1977-10-14 Cerm Cent Europ Rech Mauvernay Nouveaux composes tricycliques a cycle furannique et leur application comme antidepresseurs
SE7801074L (sv) * 1977-02-08 1978-08-09 Sandoz Ag Organiska foreningar, deras framstellning och anvendning
US4470990A (en) * 1983-03-14 1984-09-11 Ayerst, Mckenna & Harrison Inc. 6,7,8,9-Tetrahydronaphtho(1,2-B)furan-8-amine derivatives and their use as dopamine receptor stimulants
FR2613365B1 (fr) * 1987-04-01 1989-07-28 Adir Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
EP0332246A1 (de) * 1988-03-11 1989-09-13 Akzo N.V. Trizyklische Amin-Derivate
DK0389425T3 (da) * 1989-03-22 1995-05-22 Ciba Geigy Ag Benzothiopyranylaminer
US5180736A (en) * 1989-03-23 1993-01-19 Warner-Lambert Company Polycyclic amines useful as cerebrovascular agents
FR2656606B1 (fr) * 1989-12-28 1993-06-25 Roussel Uclaf Utilisation de derives du 9,10-dihydrophenanthrene pour la preparation d'un medicament anti-tumoral, application a titre de medicaments de derives du 9,10-dihydrophenanthrene et produits derives de cette structure.
JPH059179A (ja) * 1990-09-27 1993-01-19 Takeda Chem Ind Ltd 複素環化合物、その製造法及びａｃａｔ阻害剤
US5141960A (en) * 1991-06-25 1992-08-25 G. D. Searle & Co. Tricyclic glycinamide derivatives as anti-convulsants
US5538986A (en) * 1993-12-06 1996-07-23 Schering Corporation Tricyclic derivatives, compositions and methods of use

Also Published As

Publication number Publication date
NZ299560A (en) 1997-06-24
DE69630854D1 (de) 2004-01-08
DK0768307T3 (da) 2004-04-05
NO964336L (no) 1997-04-14
JPH09110858A (ja) 1997-04-28
DE69630854T2 (de) 2004-08-26
ES2211941T3 (es) 2004-07-16
EP0768307B1 (de) 2003-11-26
CN1152572A (zh) 1997-06-25
NO964336D0 (no) 1996-10-11
FR2739855B1 (fr) 1997-11-14
PT768307E (pt) 2004-03-31
EP0768307A1 (de) 1997-04-16
CN1150183C (zh) 2004-05-19
FR2739855A1 (fr) 1997-04-18
ATE255100T1 (de) 2003-12-15
US5726208A (en) 1998-03-10
AU6816896A (en) 1997-04-17
CA2187591C (fr) 2001-08-14
CA2187591A1 (fr) 1997-04-14
ZA968614B (en) 1997-05-13
AU706831B2 (en) 1999-06-24

Similar Documents

Publication Publication Date Title
EP1337528B1 (de) Benzothiophenderivate, verhahren zu ihrer herstellung und ihre verwendung
LV12630B (en) 2-aminoindans as selective dopamine d3 ligands
KR102900525B1 (ko) 아세나핀의 제조 방법
JP2010503611A (ja) アセナピンを調製するための方法、および前記方法で使用される中間生成物
CA3196103A1 (en) Substituted 6,7-dihydro-5h-benzo[7]annulene compounds and their derivatives, processes for their preparation and therapeutic uses thereof
HU190703B (en) Process for preparing new 1,2,3,4,4a,5,10,10a-octahydro-benzo/g/-quinoline derivatives
HU218668B (hu) Eljárás gyűrűben helyettesített 2-amino-1,2,3,4-tetrahidronaftalinek, 3-amino-krománok és a vegyületeket tartalmazó gyógyszerkészítmények előállítására
EP0254737B1 (de) Kondensierte benzazepine
US4973586A (en) Fused benzazepines, compositions of, and medical use thereof
AU8033498A (en) Novel tricyclic compounds having saturated rings and medicinal compositions containing the same
NO811229L (no) Fremgangsmaate ved fremstilling av nye tricykliske etere
NO314582B1 (no) Nye heterocykliske terti¶re aminer, fremgangsmåte ved deres fremstilling ogfarmasöytiske sammensetninger inneholdende dem
Booker-Milburn et al. Azabenzocycloheptenones. Part 20. Synthesis and utilisation of 4-amino-1, 2, 3, 4-tetrahydro-1 (1 H)-benzazepines
EP0299101B1 (de) Kondensierte Benzazepine
JP3541952B2 (ja) ４−アリールイソインドール鎮痛薬
US5670666A (en) Process for preparing intermediates for the synthesis of D1 antagonists
NO178496B (no) Kinolin-2-yl-metoksybenzylhydroksyurea
NO175744B (no) Fremgangsmåte for enantiospesifikk syntese av mellomprodukter for heksahydrobenzo(d)nafto(2,1-b)azepiner
Jiménez et al. Derivatives of benzo [4, 5] cyclohepta [1, 2‐b] thiophene. 4. Synthesis of 1‐(9, 10‐dihydro‐4H‐benzo [4, 5] cyclohepta [1, 2‐b] thiophen‐4‐yl)‐3‐alkylaminoazetidines
US5659037A (en) Process for preparing chiral tetracyclic dopaminergic compounds
BR102013026030A2 (pt) Processo de síntese do 3-(2-bromo-4,5-dimetóxi fenil)propano nitrila, e aplicaçâo à síntese da ivabradina e de seus sais de adição a um ácido farmaceuticamente aceitável
NO174958B (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive tetralinderivater
HK29493A (en) Fused benzazepines
NO853151L (no) Fremgangsmaate for fremstilling av terapeutisk aktive fenetanolamin-derivater.
NO750579L (de)

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees