DK0781095T3 - Celler der bærer CD4 lokkeduereceptorer og beslægtede molekyler og fremgangsmåder - Google Patents

Celler der bærer CD4 lokkeduereceptorer og beslægtede molekyler og fremgangsmåder

Info

Publication number
DK0781095T3
DK0781095T3 DK95928152T DK95928152T DK0781095T3 DK 0781095 T3 DK0781095 T3 DK 0781095T3 DK 95928152 T DK95928152 T DK 95928152T DK 95928152 T DK95928152 T DK 95928152T DK 0781095 T3 DK0781095 T3 DK 0781095T3
Authority
DK
Denmark
Prior art keywords
receptors
bait
duct
methods
cells carrying
Prior art date
Application number
DK95928152T
Other languages
English (en)
Inventor
Charles Romeo
Brian Seed
Babak Banapour
Waldemar Kolanus
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/284,391 external-priority patent/US5851828A/en
Priority claimed from US08/394,388 external-priority patent/US6753162B1/en
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Application granted granted Critical
Publication of DK0781095T3 publication Critical patent/DK0781095T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Feed For Specific Animals (AREA)
DK95928152T 1994-08-02 1995-07-26 Celler der bærer CD4 lokkeduereceptorer og beslægtede molekyler og fremgangsmåder DK0781095T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/284,391 US5851828A (en) 1991-03-07 1994-08-02 Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
US08/394,388 US6753162B1 (en) 1991-03-07 1995-02-24 Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
PCT/US1995/009468 WO1996003883A1 (en) 1994-08-02 1995-07-26 Cells bearing cd4 decoy receptors and related molecules and methods

Publications (1)

Publication Number Publication Date
DK0781095T3 true DK0781095T3 (da) 2003-06-23

Family

ID=26962581

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95928152T DK0781095T3 (da) 1994-08-02 1995-07-26 Celler der bærer CD4 lokkeduereceptorer og beslægtede molekyler og fremgangsmåder

Country Status (21)

Country Link
EP (1) EP0781095B1 (da)
JP (1) JP3832856B2 (da)
KR (1) KR100384249B1 (da)
CN (1) CN1142941C (da)
AT (1) ATE234011T1 (da)
AU (1) AU697489B2 (da)
CA (1) CA2195653C (da)
CZ (1) CZ293943B6 (da)
DE (1) DE69529910T2 (da)
DK (1) DK0781095T3 (da)
ES (1) ES2191058T3 (da)
FI (1) FI119868B (da)
HU (1) HU221603B (da)
IL (1) IL114778A (da)
MX (1) MX9700800A (da)
NO (1) NO325081B1 (da)
NZ (1) NZ291017A (da)
PL (1) PL181085B1 (da)
PT (1) PT781095E (da)
UA (1) UA45349C2 (da)
WO (1) WO1996003883A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544523B1 (en) 1996-11-13 2003-04-08 Chiron Corporation Mutant forms of Fas ligand and uses thereof
CZ20011026A3 (cs) * 1998-09-23 2001-08-15 Zymogenetics, Inc. Izolovaný polynukleotid, expresní vektor, kultivovaná buňka, konstrukt DNA, způsob produkce proteinu, izolovaný polypeptid, způsob produkce protilátky, protilátka a způsob detekce
UY35468A (es) 2013-03-16 2014-10-31 Novartis Ag Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
KR20170127015A (ko) * 2015-03-13 2017-11-20 유니버시티 오브 매릴랜드, 발티모어 만능항체 매개 바이오센서
KR102011789B1 (ko) 2015-08-05 2019-08-19 주식회사 셀랩메드 키메라 항원 수용체 및 키메라 항원 수용체가 발현된 t 세포
JP6991131B2 (ja) * 2015-09-22 2022-02-03 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア Ｈｉｖ感染症を処置するためにｔ細胞を再度方向付ける方法
US20220348628A1 (en) * 2019-09-24 2022-11-03 The Regents Of The University Of California Novel receptors having a fibronectin repeat for ligand-dependent transcriptional regulation
US20220340637A1 (en) * 2019-09-24 2022-10-27 The Regents Of The University Of California Notch receptors with minimal linker
WO2021061862A1 (en) * 2019-09-24 2021-04-01 The Regents Of The University Of California Notch receptors with hinge domain
CN114728174A (zh) * 2019-09-24 2022-07-08 加利福尼亚大学董事会 具有异源跨膜结构域的受体
CN112176037A (zh) * 2020-09-24 2021-01-05 深圳普瑞金生物药业有限公司 检测car-t细胞目的基因拷贝数的方法、引物对、探针及试剂盒
EP4112639A1 (en) * 2021-07-02 2023-01-04 Universitat de Barcelona Car t/nk-cells for use in the treatment of invasive fungal infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6463394A (en) * 1987-09-04 1989-03-09 Kyowa Hakko Kogyo Kk Novel chimera polypeptide
ZA89430B (en) * 1988-01-22 1989-10-25 Gen Hospital Corp Cloned genes encoding ig-cd4 fusion proteins and the use thereof
US5851828A (en) * 1991-03-07 1998-12-22 The General Hospital Corporation Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
IE920716A1 (en) * 1991-03-07 1992-09-09 Gen Hospital Corp Redirection of cellular immunity by receptor chimeras

Also Published As

Publication number Publication date
DE69529910T2 (de) 2003-12-18
FI970428A0 (fi) 1997-01-31
CN1158552A (zh) 1997-09-03
PL318443A1 (en) 1997-06-09
EP0781095B1 (en) 2003-03-12
AU697489B2 (en) 1998-10-08
CA2195653C (en) 2010-04-27
PT781095E (pt) 2003-06-30
UA45349C2 (uk) 2002-04-15
JPH10503932A (ja) 1998-04-14
MX9700800A (es) 1997-11-29
FI119868B (fi) 2009-04-30
EP0781095A4 (en) 1999-03-03
HU221603B (hu) 2002-11-28
JP3832856B2 (ja) 2006-10-11
NO325081B1 (no) 2008-01-28
EP0781095A1 (en) 1997-07-02
ATE234011T1 (de) 2003-03-15
AU3201495A (en) 1996-03-04
NO970440L (no) 1997-03-26
NZ291017A (en) 1998-05-27
HUT77253A (hu) 1998-03-02
FI970428L (fi) 1997-03-26
WO1996003883A1 (en) 1996-02-15
CZ26497A3 (en) 1997-10-15
KR970704357A (ko) 1997-09-06
CN1142941C (zh) 2004-03-24
IL114778A0 (en) 1995-11-27
CA2195653A1 (en) 1996-02-15
CZ293943B6 (cs) 2004-08-18
DE69529910D1 (de) 2003-04-17
IL114778A (en) 2008-08-07
ES2191058T3 (es) 2003-09-01
HK1002545A1 (zh) 1998-09-04
NO970440D0 (no) 1997-01-31
PL181085B1 (pl) 2001-05-31
KR100384249B1 (ko) 2003-08-30

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