HUT77253A - CD4-csalireceptorokat és rokonszerkezetű molekulákat hordozó sejtek és alkalmazásuk - Google Patents

CD4-csalireceptorokat és rokonszerkezetű molekulákat hordozó sejtek és alkalmazásuk

Info

Publication number
HUT77253A
HUT77253A HU9700303A HU9700303A HUT77253A HU T77253 A HUT77253 A HU T77253A HU 9700303 A HU9700303 A HU 9700303A HU 9700303 A HU9700303 A HU 9700303A HU T77253 A HUT77253 A HU T77253A
Authority
HU
Hungary
Prior art keywords
receptors
cells
carrying
related molecules
hiv
Prior art date
Application number
HU9700303A
Other languages
English (en)
Other versions
HU221603B (hu
Inventor
Babak Banapour
Waldemar Kolanus
Charles Romeo
Brian Seed
Original Assignee
The General Hospital Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/284,391 external-priority patent/US5851828A/en
Priority claimed from US08/394,388 external-priority patent/US6753162B1/en
Application filed by The General Hospital Corporation filed Critical The General Hospital Corporation
Publication of HUT77253A publication Critical patent/HUT77253A/hu
Publication of HU221603B publication Critical patent/HU221603B/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Feed For Specific Animals (AREA)
HU9700303A 1994-08-02 1995-07-26 CD4-csapdareceptorokat és rokonszerkezetű molekulákat hordozó sejtek és alkalmazásuk HU221603B (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/284,391 US5851828A (en) 1991-03-07 1994-08-02 Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
US08/394,388 US6753162B1 (en) 1991-03-07 1995-02-24 Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
PCT/US1995/009468 WO1996003883A1 (en) 1994-08-02 1995-07-26 Cells bearing cd4 decoy receptors and related molecules and methods

Publications (2)

Publication Number Publication Date
HUT77253A true HUT77253A (hu) 1998-03-02
HU221603B HU221603B (hu) 2002-11-28

Family

ID=26962581

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9700303A HU221603B (hu) 1994-08-02 1995-07-26 CD4-csapdareceptorokat és rokonszerkezetű molekulákat hordozó sejtek és alkalmazásuk

Country Status (21)

Country Link
EP (1) EP0781095B1 (hu)
JP (1) JP3832856B2 (hu)
KR (1) KR100384249B1 (hu)
CN (1) CN1142941C (hu)
AT (1) ATE234011T1 (hu)
AU (1) AU697489B2 (hu)
CA (1) CA2195653C (hu)
CZ (1) CZ293943B6 (hu)
DE (1) DE69529910T2 (hu)
DK (1) DK0781095T3 (hu)
ES (1) ES2191058T3 (hu)
FI (1) FI119868B (hu)
HU (1) HU221603B (hu)
IL (1) IL114778A (hu)
MX (1) MX9700800A (hu)
NO (1) NO325081B1 (hu)
NZ (1) NZ291017A (hu)
PL (1) PL181085B1 (hu)
PT (1) PT781095E (hu)
UA (1) UA45349C2 (hu)
WO (1) WO1996003883A1 (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544523B1 (en) 1996-11-13 2003-04-08 Chiron Corporation Mutant forms of Fas ligand and uses thereof
AU772172B2 (en) * 1998-09-23 2004-04-08 Zymogenetics Inc. Cytokine receptor zalpha11
TWI654206B (zh) 2013-03-16 2019-03-21 諾華公司 使用人類化抗－ｃｄ１９嵌合抗原受體治療癌症
KR20170127015A (ko) * 2015-03-13 2017-11-20 유니버시티 오브 매릴랜드, 발티모어 만능항체 매개 바이오센서
US10975148B2 (en) 2015-08-05 2021-04-13 CellabMED Inc. Chimeric antigen receptors, and T cells in which chimeric antigen receptor is expressed
US10738099B2 (en) * 2015-09-22 2020-08-11 The Trustees Of The University Of Pennsylvania Method of redirecting T cells to treat HIV infection
HRP20250135T1 (hr) * 2019-09-24 2025-03-28 The Regents Of The University Of California Notch receptori sa zglobnom domenom
WO2021061856A1 (en) * 2019-09-24 2021-04-01 The Regents Of The University Of California Receptors with heterologous transmembrane domain
US20220348628A1 (en) * 2019-09-24 2022-11-03 The Regents Of The University Of California Novel receptors having a fibronectin repeat for ligand-dependent transcriptional regulation
CN114728172A (zh) * 2019-09-24 2022-07-08 加利福尼亚大学董事会 具有最小接头的Notch受体
CN112176037A (zh) * 2020-09-24 2021-01-05 深圳普瑞金生物药业有限公司 检测car-t细胞目的基因拷贝数的方法、引物对、探针及试剂盒
EP4112639A1 (en) * 2021-07-02 2023-01-04 Universitat de Barcelona Car t/nk-cells for use in the treatment of invasive fungal infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6463394A (en) * 1987-09-04 1989-03-09 Kyowa Hakko Kogyo Kk Novel chimera polypeptide
PT89484B (pt) * 1988-01-22 1994-03-31 Gen Hospital Corp Genes clonados codificadores de proteinas de fusao ig-cd4 e sua utilizacao
US5851828A (en) * 1991-03-07 1998-12-22 The General Hospital Corporation Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
IL101147A (en) * 1991-03-07 2004-06-20 Gen Hospital Corp Redirection of cellular immunity by receptor chimeras

Also Published As

Publication number Publication date
HK1002545A1 (zh) 1998-09-04
JPH10503932A (ja) 1998-04-14
KR970704357A (ko) 1997-09-06
FI970428L (fi) 1997-03-26
IL114778A0 (en) 1995-11-27
NO970440L (no) 1997-03-26
ES2191058T3 (es) 2003-09-01
EP0781095B1 (en) 2003-03-12
PL318443A1 (en) 1997-06-09
HU221603B (hu) 2002-11-28
PT781095E (pt) 2003-06-30
PL181085B1 (pl) 2001-05-31
KR100384249B1 (ko) 2003-08-30
JP3832856B2 (ja) 2006-10-11
CN1142941C (zh) 2004-03-24
UA45349C2 (uk) 2002-04-15
EP0781095A1 (en) 1997-07-02
CA2195653C (en) 2010-04-27
NO325081B1 (no) 2008-01-28
WO1996003883A1 (en) 1996-02-15
FI970428A0 (fi) 1997-01-31
ATE234011T1 (de) 2003-03-15
AU3201495A (en) 1996-03-04
CZ293943B6 (cs) 2004-08-18
EP0781095A4 (en) 1999-03-03
DE69529910T2 (de) 2003-12-18
DE69529910D1 (de) 2003-04-17
FI119868B (fi) 2009-04-30
CN1158552A (zh) 1997-09-03
CZ26497A3 (en) 1997-10-15
NO970440D0 (no) 1997-01-31
AU697489B2 (en) 1998-10-08
IL114778A (en) 2008-08-07
CA2195653A1 (en) 1996-02-15
NZ291017A (en) 1998-05-27
DK0781095T3 (da) 2003-06-23
MX9700800A (es) 1997-11-29

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