MX9700800A - Células portadoras de receptores de señuelo cd4 y moléculas y métodos relacionados. - Google Patents
Células portadoras de receptores de señuelo cd4 y moléculas y métodos relacionados.Info
- Publication number
- MX9700800A MX9700800A MX9700800A MX9700800A MX9700800A MX 9700800 A MX9700800 A MX 9700800A MX 9700800 A MX9700800 A MX 9700800A MX 9700800 A MX9700800 A MX 9700800A MX 9700800 A MX9700800 A MX 9700800A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- receptors
- related molecules
- cells bearing
- decoy receptors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/46—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70514—CD4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Feed For Specific Animals (AREA)
Abstract
Se divulga un método para tratar HIV en un mamífero, que implica administrar al mamífero una cantidad efectiva de células terapéuticas que expresan un receptor quimérico proteico, ligado a membrana, que comprende una porcion extracelular que incluye un fragmento de CD4 que es capaz de reconocer y ligar específicamente la célula infectada con HIV pero que no media la infeccion de HIV. También se divulgan células que expresan estos receptores CD4 y vectores que codifican los receptores.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/284,391 US5851828A (en) | 1991-03-07 | 1994-08-02 | Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells |
| US08/394,388 US6753162B1 (en) | 1991-03-07 | 1995-02-24 | Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells |
| PCT/US1995/009468 WO1996003883A1 (en) | 1994-08-02 | 1995-07-26 | Cells bearing cd4 decoy receptors and related molecules and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9700800A true MX9700800A (es) | 1997-11-29 |
Family
ID=26962581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9700800A MX9700800A (es) | 1994-08-02 | 1995-07-26 | Células portadoras de receptores de señuelo cd4 y moléculas y métodos relacionados. |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0781095B1 (es) |
| JP (1) | JP3832856B2 (es) |
| KR (1) | KR100384249B1 (es) |
| CN (1) | CN1142941C (es) |
| AT (1) | ATE234011T1 (es) |
| AU (1) | AU697489B2 (es) |
| CA (1) | CA2195653C (es) |
| CZ (1) | CZ293943B6 (es) |
| DE (1) | DE69529910T2 (es) |
| DK (1) | DK0781095T3 (es) |
| ES (1) | ES2191058T3 (es) |
| FI (1) | FI119868B (es) |
| HU (1) | HU221603B (es) |
| IL (1) | IL114778A (es) |
| MX (1) | MX9700800A (es) |
| NO (1) | NO325081B1 (es) |
| NZ (1) | NZ291017A (es) |
| PL (1) | PL181085B1 (es) |
| PT (1) | PT781095E (es) |
| UA (1) | UA45349C2 (es) |
| WO (1) | WO1996003883A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6544523B1 (en) | 1996-11-13 | 2003-04-08 | Chiron Corporation | Mutant forms of Fas ligand and uses thereof |
| DE69941126D1 (de) * | 1998-09-23 | 2009-08-27 | Zymogenetics Inc | Cytokinerezeptor zalpha11 |
| UY35468A (es) | 2013-03-16 | 2014-10-31 | Novartis Ag | Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19 |
| US11440946B2 (en) * | 2015-03-13 | 2022-09-13 | University Of Maryland, Baltimore | Universal antibody-mediated biosensor |
| JP6751493B2 (ja) | 2015-08-05 | 2020-09-09 | セルレブメド インコーポレーテッド | キメラ抗原受容体及びキメラ抗原受容体が発現されたｔ細胞 |
| MX2018003463A (es) * | 2015-09-22 | 2018-09-06 | Univ Pennsylvania | Método de redireccionamiento de células t para tratar la infección por virus de inmunodeficiencia humana (vih). |
| CN114728172A (zh) * | 2019-09-24 | 2022-07-08 | 加利福尼亚大学董事会 | 具有最小接头的Notch受体 |
| CN114728174A (zh) * | 2019-09-24 | 2022-07-08 | 加利福尼亚大学董事会 | 具有异源跨膜结构域的受体 |
| AU2020355031A1 (en) * | 2019-09-24 | 2022-05-19 | The Regents Of The University Of California | Notch receptors with hinge domain |
| US20220348628A1 (en) * | 2019-09-24 | 2022-11-03 | The Regents Of The University Of California | Novel receptors having a fibronectin repeat for ligand-dependent transcriptional regulation |
| CN112176037A (zh) * | 2020-09-24 | 2021-01-05 | 深圳普瑞金生物药业有限公司 | 检测car-t细胞目的基因拷贝数的方法、引物对、探针及试剂盒 |
| EP4112639A1 (en) * | 2021-07-02 | 2023-01-04 | Universitat de Barcelona | Car t/nk-cells for use in the treatment of invasive fungal infections |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6463394A (en) * | 1987-09-04 | 1989-03-09 | Kyowa Hakko Kogyo Kk | Novel chimera polypeptide |
| PT89484B (pt) * | 1988-01-22 | 1994-03-31 | Gen Hospital Corp | Genes clonados codificadores de proteinas de fusao ig-cd4 e sua utilizacao |
| IE920716A1 (en) * | 1991-03-07 | 1992-09-09 | Gen Hospital Corp | Redirection of cellular immunity by receptor chimeras |
| US5851828A (en) * | 1991-03-07 | 1998-12-22 | The General Hospital Corporation | Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells |
-
1995
- 1995-07-26 MX MX9700800A patent/MX9700800A/es active IP Right Grant
- 1995-07-26 AU AU32014/95A patent/AU697489B2/en not_active Expired
- 1995-07-26 KR KR1019970700681A patent/KR100384249B1/ko not_active Expired - Lifetime
- 1995-07-26 HU HU9700303A patent/HU221603B/hu unknown
- 1995-07-26 CZ CZ1997264A patent/CZ293943B6/cs not_active IP Right Cessation
- 1995-07-26 EP EP95928152A patent/EP0781095B1/en not_active Expired - Lifetime
- 1995-07-26 CA CA2195653A patent/CA2195653C/en not_active Expired - Lifetime
- 1995-07-26 UA UA97020482A patent/UA45349C2/uk unknown
- 1995-07-26 WO PCT/US1995/009468 patent/WO1996003883A1/en not_active Ceased
- 1995-07-26 AT AT95928152T patent/ATE234011T1/de active
- 1995-07-26 NZ NZ291017A patent/NZ291017A/en not_active IP Right Cessation
- 1995-07-26 PT PT95928152T patent/PT781095E/pt unknown
- 1995-07-26 JP JP50660096A patent/JP3832856B2/ja not_active Expired - Lifetime
- 1995-07-26 CN CNB951951831A patent/CN1142941C/zh not_active Expired - Lifetime
- 1995-07-26 DK DK95928152T patent/DK0781095T3/da active
- 1995-07-26 PL PL95318443A patent/PL181085B1/pl unknown
- 1995-07-26 DE DE69529910T patent/DE69529910T2/de not_active Expired - Lifetime
- 1995-07-26 ES ES95928152T patent/ES2191058T3/es not_active Expired - Lifetime
- 1995-07-30 IL IL114778A patent/IL114778A/en not_active IP Right Cessation
-
1997
- 1997-01-31 FI FI970428A patent/FI119868B/fi not_active IP Right Cessation
- 1997-01-31 NO NO19970440A patent/NO325081B1/no not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |