DK0790246T3 - Middel til potensering af nervevækstfaktoraktivitet indeholdende 1,2-ethandiolderivat eller salt deraf - Google Patents
Middel til potensering af nervevækstfaktoraktivitet indeholdende 1,2-ethandiolderivat eller salt derafInfo
- Publication number
- DK0790246T3 DK0790246T3 DK95934859T DK95934859T DK0790246T3 DK 0790246 T3 DK0790246 T3 DK 0790246T3 DK 95934859 T DK95934859 T DK 95934859T DK 95934859 T DK95934859 T DK 95934859T DK 0790246 T3 DK0790246 T3 DK 0790246T3
- Authority
- DK
- Denmark
- Prior art keywords
- salt
- agent
- growth factor
- nerve growth
- factor activity
- Prior art date
Links
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical class OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 title 1
- 102000015336 Nerve Growth Factor Human genes 0.000 title 1
- 108010025020 Nerve Growth Factor Proteins 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 229940053128 nerve growth factor Drugs 0.000 title 1
- 230000003389 potentiating effect Effects 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
- C07C217/10—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6284273A JPH08268883A (ja) | 1994-10-25 | 1994-10-25 | 1−フェニル−1,2−エタンジオール誘導体またはそ の塩を含有する神経成長因子の作用増強剤 |
| JP28427294 | 1994-10-25 | ||
| PCT/JP1995/002162 WO1996012717A1 (en) | 1994-10-25 | 1995-10-20 | Potentiator for nerve growth factor activity containing 1,2-ethanediol derivative or salt thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0790246T3 true DK0790246T3 (da) | 2002-03-18 |
Family
ID=26555404
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95934859T DK0790246T3 (da) | 1994-10-25 | 1995-10-20 | Middel til potensering af nervevækstfaktoraktivitet indeholdende 1,2-ethandiolderivat eller salt deraf |
| DK00100580T DK1020427T3 (da) | 1994-10-25 | 1995-10-20 | Middel til at potensere nervevækstfaktoraktivitet indeholdende 1,2-ethandiolderivater eller salte deraf |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00100580T DK1020427T3 (da) | 1994-10-25 | 1995-10-20 | Middel til at potensere nervevækstfaktoraktivitet indeholdende 1,2-ethandiolderivater eller salte deraf |
Country Status (16)
| Country | Link |
|---|---|
| US (6) | US5807887A (da) |
| EP (3) | EP1223169A1 (da) |
| JP (1) | JP3218247B2 (da) |
| KR (1) | KR100447738B1 (da) |
| AU (1) | AU700561B2 (da) |
| CA (1) | CA2202032C (da) |
| CZ (1) | CZ293528B6 (da) |
| DE (2) | DE69525063T2 (da) |
| DK (2) | DK0790246T3 (da) |
| ES (2) | ES2208156T3 (da) |
| HU (1) | HU226980B1 (da) |
| NZ (1) | NZ294328A (da) |
| PL (2) | PL187490B1 (da) |
| RO (1) | RO119196B1 (da) |
| TW (1) | TW341570B (da) |
| WO (1) | WO1996012717A1 (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0790246T3 (da) * | 1994-10-25 | 2002-03-18 | Toyama Chemical Co Ltd | Middel til potensering af nervevækstfaktoraktivitet indeholdende 1,2-ethandiolderivat eller salt deraf |
| AU2576797A (en) * | 1996-04-22 | 1997-11-12 | Toyama Chemical Co. Ltd. | Patch containing 1,2-ethanediol derivatives or salts thereof |
| WO1999031056A1 (en) * | 1997-12-12 | 1999-06-24 | Toyama Chemical Co., Ltd. | Alkyl ether derivatives or salts thereof and calcium antagonists containing the same |
| JP4549452B2 (ja) * | 1997-12-12 | 2010-09-22 | 富山化学工業株式会社 | アルキルエーテル誘導体またはその塩並びにそれらを含有するカルシウム拮抗剤 |
| PL196773B1 (pl) * | 1999-06-11 | 2008-01-31 | Toyama Chemical Co Ltd | Pochodna N-alkiloksyalkilo-N,N-dialkiloaminy lub jej sole oraz środek zawierający ten związek stosowany do leczenia chorób neurodegeneratywnych |
| AU9235101A (en) * | 2000-10-10 | 2002-04-22 | Toyama Chemical Co Ltd | Remedies for retinal nerve diseases containing 1,2-ethanediol derivatives or salts thereof |
| CA2464358C (en) * | 2001-10-19 | 2011-05-24 | Toyama Chemical Co., Ltd. | Alkyl ether derivatives or their salts |
| KR100935615B1 (ko) | 2002-06-14 | 2010-01-07 | 토야마 케미칼 컴퍼니 리미티드 | 뇌기능을 개선하는 의약조성물 및 뇌기능을 개선하기 위한방법 |
| PL1606409T3 (pl) | 2003-03-19 | 2011-02-28 | Biogen Ma Inc | Białko wiążące receptor Nogo |
| PT1776136E (pt) | 2004-06-24 | 2012-12-05 | Biogen Idec Inc | Tratamento de estados que envolvem desmielinização |
| SI1904104T1 (sl) | 2005-07-08 | 2013-12-31 | Biogen Idec Ma Inc. | Protitelesa SP35 in njihova uporaba |
| EP2068866A4 (en) | 2006-07-24 | 2010-04-07 | Biogen Idec Inc | METHODS FOR PROMOTING MYELINIZATION, NEURONAL SURVIVAL AND DIFFERENTIATION OF OLIGODENDROCYTES BY ADMINISTERING SP35 OR TRKA ANTAGONISTS |
| CA2701189C (en) * | 2007-10-11 | 2017-05-16 | Biogen Idec Ma Inc. | Methods for treating pressure induced optic neuropathy, preventing neuronal degeneration and promoting neuronal cell survival via administration of lingo-1 antagonists and trkb agonists |
| WO2009061500A1 (en) * | 2007-11-08 | 2009-05-14 | Biogen Idec Ma Inc. | Use of lingo-4 antagonists in the treatment of conditions involving demyelination |
| EP2315779A2 (en) | 2008-07-09 | 2011-05-04 | Biogen Idec MA Inc. | Compositions comprising antibodies to lingo or fragments thereof |
| US9796780B2 (en) | 2012-05-14 | 2017-10-24 | Biogen Ma Inc. | LINGO-2 antagonists for treatment of conditions involving motor neurons |
| WO2016112270A1 (en) | 2015-01-08 | 2016-07-14 | Biogen Ma Inc. | Lingo-1 antagonists and uses for treatment of demyelinating disorders |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3894058A (en) * | 1974-05-17 | 1975-07-08 | Hoechst Co American | Tetrahydrobenzofuranylphenoxypropylamines |
| US5254595A (en) * | 1988-12-23 | 1993-10-19 | Elf Sanofi | Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them |
| NZ232493A (en) * | 1989-02-14 | 1992-06-25 | Toyama Chemical Co Ltd | Aryl- or heterocyclyl-substituted 1,2-ethanediol derivatives and pharmaceutical compositions |
| US5280032A (en) * | 1989-02-14 | 1994-01-18 | Toyama Chemical Co., Ltd. | 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same |
| JP3044055B2 (ja) * | 1990-08-09 | 2000-05-22 | 富山化学工業株式会社 | 1,2―エタンジオール誘導体およびその塩 |
| JPH05230103A (ja) * | 1992-02-18 | 1993-09-07 | Taisho Pharmaceut Co Ltd | ガングリオシド化合物 |
| DK0790246T3 (da) * | 1994-10-25 | 2002-03-18 | Toyama Chemical Co Ltd | Middel til potensering af nervevækstfaktoraktivitet indeholdende 1,2-ethandiolderivat eller salt deraf |
-
1995
- 1995-10-20 DK DK95934859T patent/DK0790246T3/da active
- 1995-10-20 PL PL95359927A patent/PL187490B1/pl not_active IP Right Cessation
- 1995-10-20 EP EP02004782A patent/EP1223169A1/en not_active Withdrawn
- 1995-10-20 NZ NZ294328A patent/NZ294328A/en not_active IP Right Cessation
- 1995-10-20 WO PCT/JP1995/002162 patent/WO1996012717A1/ja not_active Ceased
- 1995-10-20 DE DE69525063T patent/DE69525063T2/de not_active Expired - Fee Related
- 1995-10-20 JP JP51377896A patent/JP3218247B2/ja not_active Expired - Fee Related
- 1995-10-20 DE DE69531877T patent/DE69531877T2/de not_active Expired - Fee Related
- 1995-10-20 DK DK00100580T patent/DK1020427T3/da active
- 1995-10-20 ES ES00100580T patent/ES2208156T3/es not_active Expired - Lifetime
- 1995-10-20 US US08/809,407 patent/US5807887A/en not_active Expired - Fee Related
- 1995-10-20 RO RO97-00775A patent/RO119196B1/ro unknown
- 1995-10-20 HU HU9701903A patent/HU226980B1/hu not_active IP Right Cessation
- 1995-10-20 CZ CZ19971249A patent/CZ293528B6/cs not_active IP Right Cessation
- 1995-10-20 PL PL95319940A patent/PL187004B1/pl not_active IP Right Cessation
- 1995-10-20 EP EP95934859A patent/EP0790246B1/en not_active Expired - Lifetime
- 1995-10-20 KR KR1019970702690A patent/KR100447738B1/ko not_active Expired - Fee Related
- 1995-10-20 EP EP00100580A patent/EP1020427B1/en not_active Expired - Lifetime
- 1995-10-20 ES ES95934859T patent/ES2171559T3/es not_active Expired - Lifetime
- 1995-10-20 AU AU37097/95A patent/AU700561B2/en not_active Ceased
- 1995-10-20 CA CA002202032A patent/CA2202032C/en not_active Expired - Fee Related
- 1995-10-23 TW TW084111184A patent/TW341570B/zh active
-
1997
- 1997-12-31 US US09/001,656 patent/US5922721A/en not_active Expired - Fee Related
- 1997-12-31 US US09/001,651 patent/US5932620A/en not_active Expired - Fee Related
- 1997-12-31 US US09/001,650 patent/US5968935A/en not_active Expired - Fee Related
-
1999
- 1999-02-18 US US09/252,199 patent/US6034119A/en not_active Expired - Fee Related
- 1999-03-09 US US09/264,713 patent/US6103754A/en not_active Expired - Fee Related
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