DK0797987T3 - Granulært præparat med langvarig frigivelse og fremgangsmåde til fremstilling deraf - Google Patents

Granulært præparat med langvarig frigivelse og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0797987T3
DK0797987T3 DK95940461T DK95940461T DK0797987T3 DK 0797987 T3 DK0797987 T3 DK 0797987T3 DK 95940461 T DK95940461 T DK 95940461T DK 95940461 T DK95940461 T DK 95940461T DK 0797987 T3 DK0797987 T3 DK 0797987T3
Authority
DK
Denmark
Prior art keywords
preparation
sustained
release
granular preparations
release granular
Prior art date
Application number
DK95940461T
Other languages
Danish (da)
English (en)
Inventor
Hiroaki
Masazumi
Shinji
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of DK0797987T3 publication Critical patent/DK0797987T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK95940461T 1994-12-19 1995-12-18 Granulært præparat med langvarig frigivelse og fremgangsmåde til fremstilling deraf DK0797987T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP31441494 1994-12-19
PCT/JP1995/002594 WO1996019200A1 (en) 1994-12-19 1995-12-18 Sustained-release granular preparation and process for producing the same

Publications (1)

Publication Number Publication Date
DK0797987T3 true DK0797987T3 (da) 2004-02-16

Family

ID=18053063

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95940461T DK0797987T3 (da) 1994-12-19 1995-12-18 Granulært præparat med langvarig frigivelse og fremgangsmåde til fremstilling deraf

Country Status (14)

Country Link
US (2) US5858411A (de)
EP (1) EP0797987B1 (de)
JP (1) JP3893439B2 (de)
KR (1) KR100424931B1 (de)
CN (1) CN1093758C (de)
AT (1) ATE251896T1 (de)
DE (1) DE69531957T2 (de)
DK (1) DK0797987T3 (de)
ES (1) ES2210321T3 (de)
FI (1) FI119720B (de)
NO (1) NO320356B1 (de)
PT (1) PT797987E (de)
TW (1) TW406022B (de)
WO (1) WO1996019200A1 (de)

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US6579953B1 (en) 1998-09-30 2003-06-17 Basf Aktiengesellschaft Application of water-soluble or water-dispersible polymerizates which contain poly-ether and which are used as a coating agent, a binding agent and/or as a film-forming auxiliary agent in pharmaceutical forms of administration
EP1027885B1 (de) * 1999-02-09 2008-07-09 Pfizer Products Inc. Zusammensetzungen basischer Arzneistoffe mit verbesserter Bioverfügbarkeit
US6316462B1 (en) 1999-04-09 2001-11-13 Schering Corporation Methods of inducing cancer cell death and tumor regression
GB0003782D0 (en) * 2000-02-17 2000-04-05 Dumex Ltd As Process
JP4310605B2 (ja) * 2001-05-25 2009-08-12 大塚製薬株式会社 医薬用組成物
US20090214644A1 (en) * 2003-07-31 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations with reduced adverse effects
US20050025825A1 (en) * 2003-07-31 2005-02-03 Xanodyne Pharmacal, Inc. Tranexamic acid formulations with reduced adverse effects
US20050244495A1 (en) * 2004-03-04 2005-11-03 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US20050245614A1 (en) * 2004-03-04 2005-11-03 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US8022106B2 (en) * 2004-03-04 2011-09-20 Ferring B.V. Tranexamic acid formulations
US20090215898A1 (en) 2004-03-04 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US7947739B2 (en) 2004-03-04 2011-05-24 Ferring B.V. Tranexamic acid formulations
JP5205053B2 (ja) * 2004-07-30 2013-06-05 フェリング ビー．ブイ． トラネキサム酸製剤
US20070059359A1 (en) * 2005-06-07 2007-03-15 Thomas Backensfeld Immediate-release and high-drug-load pharmaceutical formulations of non-micronised (4-chlorophenyl)[4-(4-pyridylmethyl)phthalazin-1-yl] and salts thereof
US20060275365A1 (en) * 2005-06-07 2006-12-07 Thomas Backensfeld Immediate-release and high-drug-load pharmaceutical formulations of micronised (4-chlorophenyl) [4-(4-pyridylmethyl)phthalazin-1-yl] and salts thereof
WO2006133349A2 (en) * 2005-06-08 2006-12-14 Alpharma, Inc. Orally disintegrable sleep aid formulations
EP1919859B1 (de) 2005-06-20 2010-06-02 Xenoport, Inc. Acyloxyalkylcarbamat-prodrugs von tranexansäure und anwendung
US20070036859A1 (en) * 2005-08-11 2007-02-15 Perry Ronald L Sustained release antihistamine and decongestant composition
DK2001445T3 (da) * 2006-03-16 2014-10-27 Euro Celtique Farmaceutiske sfæroider
MX2008010233A (es) * 2008-03-10 2009-11-10 Eurodrug Lab B V Composicion de liberacion modificada, que comprende doxofilina.
US20100280117A1 (en) * 2009-04-30 2010-11-04 Xanodyne Pharmaceuticals, Inc. Menorrhagia Instrument and Method for the Treatment of Menstrual Bleeding Disorders
WO2011091164A1 (en) * 2010-01-22 2011-07-28 Xenoport, Inc. Oral dosage forms having a high loading of a tranexamic acid prodrug
WO2011102505A1 (ja) * 2010-02-22 2011-08-25 第一三共株式会社 経口用徐放性固形製剤
GB201010083D0 (en) * 2010-06-16 2010-07-21 Univ Bradford Compositions and methods
KR102286952B1 (ko) * 2013-12-31 2021-08-09 롯데정밀화학 주식회사 입도분포가 조절된 히드록시프로필 메틸셀룰로오스 아세테이트 숙시네이트(hpmcas) 입자의 제조방법 및 hpmcas 분말
WO2017035408A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Compounds for treatment of immune and inflammatory disorders
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
MX2018016046A (es) 2016-06-27 2019-05-02 Achillion Pharmaceuticals Inc Quinazolina y compuestos indol para tratar trastornos medicos.
CA3053818A1 (en) 2017-03-01 2018-09-07 Achillion Pharmaceuticals, Inc. Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders
EP3841086B1 (de) 2018-08-20 2025-04-23 Achillion Pharmaceuticals, Inc. Pharmazeutische zusammensetzungen zur behandlung von medizinischen störungen im zusammenhang mit komplementfaktor d
JP7443375B2 (ja) 2018-09-06 2024-03-05 アキリオン ファーマシューティカルズ， インコーポレーテッド 医学的障害の治療のための大環状化合物
CN113365617B (zh) 2018-10-16 2025-12-23 乔治亚州立大学研究基金会股份有限公司 用于医学疾病治疗的一氧化碳前药
MX2021011507A (es) 2019-03-22 2021-12-15 Achillion Pharmaceuticals Inc Compuestos farmaceuticos para el tratamiento de trastornos mediados por complemento.
CN114845708A (zh) 2019-12-19 2022-08-02 乔治亚州大学研究基金会 用于治疗细菌感染和增强抗生素的化合物
JP2023515073A (ja) 2020-02-20 2023-04-12 アキリオン ファーマシューティカルズ， インコーポレーテッド 補体因子ｄ媒介障害の処置用のヘテロアリール化合物
CA3193488A1 (en) 2020-09-23 2022-03-31 Jason Allan Wiles Pharmaceutical compounds for the treatment of complement mediated disorders

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US4330338A (en) * 1978-10-02 1982-05-18 Purdue Research Foundation Pharmaceutical coating composition, and preparation and dosages so coated
US4329451A (en) * 1980-11-03 1982-05-11 The Dow Chemical Company Preparing an aqueous dispersion of colloidal size particles of a water-insoluble polysaccharide derivative
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
JPS6143108A (ja) * 1984-08-03 1986-03-01 Nippon Shinyaku Co Ltd 医薬品製剤及びその製造法
LU86099A1 (fr) * 1985-09-30 1987-04-02 Pharlyse Formes galeniques a liberation prolongee du verapamil,leur fabrication et medicaments les contenant
CA1334379C (en) * 1987-11-24 1995-02-14 James William Mcginity Method for preparing a solid sustained release form of a functionally active composition
US5051261A (en) * 1987-11-24 1991-09-24 Fmc Corporation Method for preparing a solid sustained release form of a functionally active composition
US4835188A (en) * 1987-12-08 1989-05-30 American Home Products Corporation Spray dried ibuprofen
US4916161A (en) * 1988-10-25 1990-04-10 Bristol-Myers Squibb Taste-masking pharmaceutical agents
US5326572A (en) * 1989-03-23 1994-07-05 Fmc Corporation Freeze-dried polymer dispersions and the use thereof in preparing sustained-release pharmaceutical compositions
EP0421582A1 (de) * 1989-10-03 1991-04-10 Warner-Lambert Company Kaubare sprühgetrocknete spheroide Mikrokapseln, polymerüberzogene Mikrokapseln und Verfahren zu ihrer Herstellung
JPH03232814A (ja) * 1990-02-08 1991-10-16 Shin Etsu Chem Co Ltd 徐放性錠剤の製造方法
JP2915590B2 (ja) * 1991-02-15 1999-07-05 第一製薬株式会社 マスクされた粒状物
ES2111065T5 (es) * 1991-04-16 2005-06-16 Nippon Shinyaku Company, Limited Procedimiento para producir una dispersion solida.
DE4244466C2 (de) * 1992-12-24 1995-02-23 Pharmatech Gmbh Verfahren zur Herstellung von Pseudolatices und Mikro- oder Nanopartikeln und deren Verwendung zur Herstellung von pharmazeutischen Präparaten

Also Published As

Publication number Publication date
WO1996019200A1 (en) 1996-06-27
FI972622A0 (fi) 1997-06-18
EP0797987A4 (de) 1998-09-09
PT797987E (pt) 2004-02-27
FI972622L (fi) 1997-06-18
NO972814L (no) 1997-08-18
EP0797987A1 (de) 1997-10-01
CN1093758C (zh) 2002-11-06
ATE251896T1 (de) 2003-11-15
DE69531957T2 (de) 2004-08-12
DE69531957D1 (de) 2003-11-20
NO320356B1 (no) 2005-11-28
TW406022B (en) 2000-09-21
US6030644A (en) 2000-02-29
US5858411A (en) 1999-01-12
EP0797987B1 (de) 2003-10-15
FI119720B (fi) 2009-02-27
NO972814D0 (no) 1997-06-18
KR100424931B1 (ko) 2004-07-05
CN1170357A (zh) 1998-01-14
JP3893439B2 (ja) 2007-03-14
ES2210321T3 (es) 2004-07-01

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