DK0813541T3 - Fremgangsmåde til fremstilling af et protein - Google Patents

Fremgangsmåde til fremstilling af et protein

Info

Publication number
DK0813541T3
DK0813541T3 DK96906136T DK96906136T DK0813541T3 DK 0813541 T3 DK0813541 T3 DK 0813541T3 DK 96906136 T DK96906136 T DK 96906136T DK 96906136 T DK96906136 T DK 96906136T DK 0813541 T3 DK0813541 T3 DK 0813541T3
Authority
DK
Denmark
Prior art keywords
apoe
apoa
matrix
endotoxins
aqueous solution
Prior art date
Application number
DK96906136T
Other languages
Danish (da)
English (en)
Inventor
Hans Ageland
Lena Romander
Original Assignee
Esperion Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esperion Therapeutics Inc filed Critical Esperion Therapeutics Inc
Application granted granted Critical
Publication of DK0813541T3 publication Critical patent/DK0813541T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DK96906136T 1995-03-03 1996-03-01 Fremgangsmåde til fremstilling af et protein DK0813541T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9500778A SE9500778D0 (sv) 1995-03-03 1995-03-03 Process for producing a protein
PCT/SE1996/000271 WO1996027608A1 (en) 1995-03-03 1996-03-01 Process for producing a protein

Publications (1)

Publication Number Publication Date
DK0813541T3 true DK0813541T3 (da) 2003-09-15

Family

ID=20397430

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96906136T DK0813541T3 (da) 1995-03-03 1996-03-01 Fremgangsmåde til fremstilling af et protein

Country Status (15)

Country Link
US (3) US5834596A (de)
EP (1) EP0813541B1 (de)
JP (1) JPH11501046A (de)
AT (1) ATE240348T1 (de)
AU (1) AU694623B2 (de)
CA (1) CA2212125A1 (de)
DE (1) DE69628148T2 (de)
DK (1) DK0813541T3 (de)
ES (1) ES2199284T3 (de)
IL (1) IL117320A (de)
NZ (1) NZ303325A (de)
PT (1) PT813541E (de)
SE (1) SE9500778D0 (de)
WO (1) WO1996027608A1 (de)
ZA (1) ZA961679B (de)

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SE9500778D0 (sv) * 1995-03-03 1995-03-03 Pharmacia Ab Process for producing a protein
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SE9603303D0 (sv) 1996-09-11 1996-09-11 Pharmacia & Upjohn Ab Process for purifying a protein
SE9603304D0 (sv) 1996-09-11 1996-09-11 Pharmacia & Upjohn Ab Process for purifying a compound
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US7470659B2 (en) * 2001-12-07 2008-12-30 The Regents Of The University Of California Methods to increase reverse cholesterol transport in the retinal pigment epithelium (RPE) and Bruch's membrane (BM)
WO2003049685A2 (en) * 2001-12-07 2003-06-19 The Regents Of The University Of California Treatment for age-related macular degeneration
US20030229062A1 (en) * 2001-12-07 2003-12-11 The Regents Of The University Of California Treatments for age-related macular degeneration (AMD)
NZ537006A (en) * 2002-05-17 2008-01-31 Esperion Therapeutics Inc The use of apolipoprotein A-I Milano, for the manufacture ofa composition for treating preventing or reducing ischemic reperfusion injury in a tissue or organ
CA2513660C (en) * 2003-01-23 2012-05-08 Esperion Therapeutics, Inc. Hydroxyl compounds and compositions for cholesterol management and related uses
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US20050176623A1 (en) * 2004-02-11 2005-08-11 Neil Wagle Non-invasive treatment of disease using amphipathic compounds
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US20080227686A1 (en) * 2006-06-16 2008-09-18 Lipid Sciences, Inc. Novel Peptides that Promote Lipid Efflux
WO2007149355A2 (en) * 2006-06-16 2007-12-27 Lipid Sciences, Inc. Novel peptides that promote lipid efflux
EP2043767B1 (de) 2006-07-14 2020-03-25 Wisconsin Alumni Research Foundation Adsorptionsmembranen zum einfangen von viren
WO2008021088A2 (en) 2006-08-08 2008-02-21 The Regents Of The University Of Californina Salicylanilides enhance oral delivery of therapeutic peptides
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US8013122B2 (en) * 2006-12-20 2011-09-06 Kieu Hoang Method of purifying apolipoprotein A-1
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EP2464336A4 (de) 2009-08-14 2013-11-20 Alnylam Pharmaceuticals Inc Zusammensetzungen aus lipidformulierungen und verfahren zur hemmung der expression eines gens aus dem ebolavirus
WO2011071860A2 (en) 2009-12-07 2011-06-16 Alnylam Pharmaceuticals, Inc. Compositions for nucleic acid delivery
EP3494963A1 (de) 2009-12-18 2019-06-12 The University of British Columbia Verfahren und zusammensetzungen zur abgabe von nukleinsäuren
US20130156845A1 (en) 2010-04-29 2013-06-20 Alnylam Pharmaceuticals, Inc. Lipid formulated single stranded rna
WO2011143362A1 (en) 2010-05-11 2011-11-17 Esperion Therapeutics, Inc. Dimeric oxidation-resistant apolipoprotein a1 variants
CA2800401C (en) 2010-06-03 2020-09-15 Alnylam Pharmaceuticals, Inc. Biodegradable lipids for the delivery of active agents
WO2012016188A2 (en) 2010-07-30 2012-02-02 Alnylam Pharmaceuticals, Inc. Methods and compositions for delivery of active agents
US20130323269A1 (en) 2010-07-30 2013-12-05 Muthiah Manoharan Methods and compositions for delivery of active agents
CN110123830A (zh) 2010-11-09 2019-08-16 阿尔尼拉姆医药品有限公司 用于抑制Eg5和VEGF基因的表达的脂质配制的组合物和方法
JP5902197B2 (ja) 2011-01-11 2016-04-13 アルニラム・ファーマシューティカルズ・インコーポレーテッド Ｐｅｇ化脂質および薬剤送達のためのそれらの使用
PT2673296T (pt) 2011-02-07 2019-01-31 Cerenis Therapeutics Holding Sa Complexos de lipoproteínas e sua fabricação e utilização
EP2760477B1 (de) 2011-09-27 2018-08-08 Alnylam Pharmaceuticals, Inc. Substituierte di-aliphatic pegylierte lipide
SG11201403207WA (en) 2011-12-12 2014-09-26 Melior Pharmaceuticals I Inc Treatment of type i and type ii diabetes
JP2015519361A (ja) * 2012-05-31 2015-07-09 エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ 正電荷有機添加剤での処理によるタンパク質製剤におけるタンパク質−不純物複合体及び凝集体のレベルを低下させるための方法
US9610324B2 (en) 2012-07-11 2017-04-04 Esperion Therapeutics, Inc. Apolipoprotein mixtures
KR20170003611A (ko) 2014-05-02 2017-01-09 세레니스 쎄라퓨틱스 홀딩 에스에이 Ｈｄｌ 요법 마커
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MA41793A (fr) 2015-03-16 2018-01-23 Esperion Therapeutics Inc Associations de doses fixes comprenant du etc1002 et une ou plusieurs statines permettant de traiter ou de réduire un risque cardiovasculaire
CN107033237B (zh) * 2017-05-11 2021-07-20 深圳市卫光生物制品股份有限公司 一种人血浆载脂蛋白a-i的分离纯化方法
EP4438114A3 (de) 2019-06-21 2024-12-25 Esperion Therapeutics, Inc. Verfahren zur herstellung von bempedosäure und zusammensetzungen davon
US20240350579A1 (en) * 2020-08-10 2024-10-24 Gel4Med, Inc. Antifungal matrix formed from peptide hydrogels

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Also Published As

Publication number Publication date
DE69628148D1 (de) 2003-06-18
US5834596A (en) 1998-11-10
WO1996027608A1 (en) 1996-09-12
DE69628148T2 (de) 2004-01-08
US6506879B1 (en) 2003-01-14
ATE240348T1 (de) 2003-05-15
US5990081A (en) 1999-11-23
AU694623B2 (en) 1998-07-23
AU4960796A (en) 1996-09-23
IL117320A0 (en) 1996-06-18
IL117320A (en) 2001-06-14
SE9500778D0 (sv) 1995-03-03
EP0813541A1 (de) 1997-12-29
NZ303325A (en) 1998-12-23
ZA961679B (en) 1996-10-07
JPH11501046A (ja) 1999-01-26
ES2199284T3 (es) 2004-02-16
CA2212125A1 (en) 1996-09-12
EP0813541B1 (de) 2003-05-14
PT813541E (pt) 2003-09-30

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