DK0836601T3 - Fremgangsmåde til optisk oprensning af enantiomert beriget benzimidasolderivater - Google Patents

Fremgangsmåde til optisk oprensning af enantiomert beriget benzimidasolderivater

Info

Publication number: DK0836601T3
Authority: DK; Denmark
Prior art keywords: enantiomerically enriched; benzimidazole derivatives; optical purification; enriched benzimidazole; purification
Prior art date: 1995-07-03

Application number

DK96922339T

Other languages

Danish (da)

English (en)

Inventor

Unge Sverker Von

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-03

Filing date

1996-06-26

Publication date

2009-03-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20397468&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0836601(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-06-26 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2009-03-16 Application granted granted Critical

2009-03-16 Publication of DK0836601T3 publication Critical patent/DK0836601T3/da

Links

238000000034 method Methods 0.000 title abstract 2
230000003287 optical effect Effects 0.000 title abstract 2
238000000746 purification Methods 0.000 title abstract 2
229940058303 antinematodal benzimidazole derivative Drugs 0.000 title 1
125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title 1
BHVRHDLXKLRTEY-UHFFFAOYSA-N 2-sulfinyl-1,3-dihydrobenzimidazole Chemical class C1=CC=C2NC(=S=O)NC2=C1 BHVRHDLXKLRTEY-UHFFFAOYSA-N 0.000 abstract 1
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
ATTZFSUZZUNHBP-UHFFFAOYSA-N Piperonyl sulfoxide Chemical compound CCCCCCCCS(=O)C(C)CC1=CC=C2OCOC2=C1 ATTZFSUZZUNHBP-UHFFFAOYSA-N 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK96922339T 1995-07-03 1996-06-26 Fremgangsmåde til optisk oprensning af enantiomert beriget benzimidasolderivater DK0836601T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9500817		1995-07-03
PCT/SE1996/000841 WO1997002261A1 (en)	1995-07-03	1996-06-26	A process for the optical purification of enantiomerically enriched benzimidazole derivatives

Publications (1)

Publication Number	Publication Date
DK0836601T3 true DK0836601T3 (da)	2009-03-16

Family

ID=20397468

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96922339T DK0836601T3 (da)	1995-07-03	1996-06-26	Fremgangsmåde til optisk oprensning af enantiomert beriget benzimidasolderivater

Country Status (36)

Country	Link
US (1)	US5929244A (zh)
EP (2)	EP0836601B1 (zh)
JP (1)	JP4195507B2 (zh)
KR (1)	KR100451078B1 (zh)
CN (1)	CN1098261C (zh)
AT (1)	ATE418549T1 (zh)
AU (1)	AU698638B2 (zh)
BR (1)	BR9609450A (zh)
CA (1)	CA2226184C (zh)
CZ (1)	CZ295430B6 (zh)
DE (1)	DE69637788D1 (zh)
DK (1)	DK0836601T3 (zh)
DZ (1)	DZ2057A1 (zh)
EE (1)	EE03444B1 (zh)
ES (1)	ES2318850T3 (zh)
HR (1)	HRP960232A2 (zh)
HU (1)	HUP9901717A3 (zh)
IL (1)	IL122811A (zh)
IS (1)	IS2666B (zh)
MA (1)	MA23921A1 (zh)
MY (1)	MY114018A (zh)
NO (1)	NO313008B1 (zh)
NZ (1)	NZ311842A (zh)
PL (1)	PL186702B1 (zh)
PT (1)	PT836601E (zh)
RS (1)	RS49826B (zh)
RU (1)	RU2144031C1 (zh)
SA (1)	SA96170103B1 (zh)
SI (1)	SI0836601T1 (zh)
SK (1)	SK284780B6 (zh)
TN (1)	TNSN96090A1 (zh)
TR (1)	TR199701754T1 (zh)
TW (1)	TW444010B (zh)
UA (1)	UA49838C2 (zh)
WO (1)	WO1997002261A1 (zh)
ZA (1)	ZA965205B (zh)

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HRP960232A2 (en) *	1995-07-03	1998-02-28	Astra Ab	A process for the optical purification of compounds
US6489346B1 (en) *	1996-01-04	2002-12-03	The Curators Of The University Of Missouri	Substituted benzimidazole dosage forms and method of using same
US6699885B2 (en) *	1996-01-04	2004-03-02	The Curators Of The University Of Missouri	Substituted benzimidazole dosage forms and methods of using same
US6645988B2 (en)	1996-01-04	2003-11-11	Curators Of The University Of Missouri	Substituted benzimidazole dosage forms and method of using same
US5840737A (en)	1996-01-04	1998-11-24	The Curators Of The University Of Missouri	Omeprazole solution and method for using same
AU6551198A (en) *	1997-05-30	1998-12-30	Dr. Reddy's Research Foundation	Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
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SE9900274D0 (sv)	1999-01-28	1999-01-28	Astra Ab	New compound
TWI275587B (en)	1999-06-17	2007-03-11	Takeda Chemical Industries Ltd	A crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
ATE298334T1 (de)	1999-06-30	2005-07-15	Takeda Pharmaceutical	Kristalle von lansoprazole
US6369087B1 (en)	1999-08-26	2002-04-09	Robert R. Whittle	Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6268385B1 (en)	1999-08-26	2001-07-31	Robert R. Whittle	Dry blend pharmaceutical formulations
US6312723B1 (en)	1999-08-26	2001-11-06	Robert R. Whittle	Pharmaceutical unit dosage form
US6326384B1 (en)	1999-08-26	2001-12-04	Robert R. Whittle	Dry blend pharmaceutical unit dosage form
US6312712B1 (en)	1999-08-26	2001-11-06	Robert R. Whittle	Method of improving bioavailability
US6262085B1 (en)	1999-08-26	2001-07-17	Robert R. Whittle	Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6780880B1 (en)	1999-08-26	2004-08-24	Robert R. Whittle	FT-Raman spectroscopic measurement
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KR100433735B1 (ko) *	2001-06-27	2004-06-04	주식회사 씨트리	결정형 ⅰ을 갖는 란소프라졸의 제조방법
SE0104295D0 (sv) *	2001-12-18	2001-12-18	Astrazeneca Ab	New process
WO2003063840A2 (en) *	2002-01-25	2003-08-07	Santarus, Inc.	Transmucosal delivery of proton pump inhibitors
WO2004035052A1 (ja)	2002-10-16	2004-04-29	Takeda Pharmaceutical Company Limited	安定な固形製剤
MY148805A (en)	2002-10-16	2013-05-31	Takeda Pharmaceutical	Controlled release preparation
DE10254167A1 (de)	2002-11-20	2004-06-09	Icon Genetics Ag	Verfahren zur Kontrolle von zellulären Prozessen in Pflanzen
ES2383679T3 (es)	2002-12-06	2012-06-25	Nycomed Gmbh	Procedimiento para la preparación de (S)-pantoprazol
AR042277A1 (es)	2002-12-06	2005-06-15	Altana Pharma Ag	Un procedimiento para la preparacion de sulfinil benzimidazoles opticamente puros
WO2004073654A2 (en) *	2003-02-20	2004-09-02	Santarus, Inc.	A novel formulation, omeprazole antacid complex-immediate release for rapid and sustained supression of gastric acid
US20060247277A1 (en) *	2003-02-28	2006-11-02	Yatendra Kumar	Polymorphs of s-omeprazole
MXPA06000524A (es) *	2003-07-18	2006-08-11	Santarus Inc	Formulacion farmaceutica y metodo para tratar desordenes gastrointestinales provocados por acido.
US8993599B2 (en)	2003-07-18	2015-03-31	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US7005732B2 (en) *	2003-10-21	2006-02-28	Honeywell International Inc.	Methods and systems for providing MEMS devices with a top cap and upper sense plate
FR2863609A1 (fr) *	2003-12-15	2005-06-17	Isochem Sa	Procede d'enrichissement enantiomerique d'un melange d'enantiomeres d'alpha-aminoacides
SE0400410D0 (sv) *	2004-02-20	2004-02-20	Astrazeneca Ab	New compounds
US8815916B2 (en) *	2004-05-25	2014-08-26	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) *	2004-05-25	2014-12-09	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8461187B2 (en)	2004-06-16	2013-06-11	Takeda Pharmaceuticals U.S.A., Inc.	Multiple PPI dosage form
FR2876101B1 (fr) *	2004-10-05	2007-03-02	Sidem Pharma Sa Sa	Procede de preparation enantioselective de derives de sulfoxydes
EP1801110A1 (en)	2005-12-22	2007-06-27	KRKA, tovarna zdravil, d.d., Novo mesto	Esomeprazole arginine salt
US7553857B2 (en)	2005-12-23	2009-06-30	Lek Pharmaceuticals D.D.	S-omeprazole magnesium
US7786309B2 (en) *	2006-06-09	2010-08-31	Apotex Pharmachem Inc.	Process for the preparation of esomeprazole and salts thereof
FR2909380B1 (fr) *	2006-12-04	2009-02-20	Sidem Pharma Sa Sa	Conglomerats de sels de potassium de tenatoprazole
EP1947099A1 (en)	2007-01-18	2008-07-23	LEK Pharmaceuticals D.D.	Process for solvent removal from omeprazole salts
CN101323609B (zh) *	2007-06-15	2013-05-01	成都福瑞生物工程有限公司	不对称氧化硫醚成亚砜合成对映体含量高的苯并咪唑衍生物的方法
WO2008152462A1 (en) *	2007-06-15	2008-12-18	Emcure Pharmaceuticals Limited	A process of sulfoxidation of biologically active compounds
FR2920428B1 (fr) *	2007-08-29	2012-06-15	Univ Rouen	Procede de dedoublement de sels de l'omeprazole
EA017064B1 (ru)	2008-03-10	2012-09-28	Такеда Фармасьютикал Компани Лимитед	Кристаллическое производное бензимидазола
US8354541B2 (en)	2008-11-18	2013-01-15	Hetero Research Foundation	Optical purification of esomeprazole
KR101001646B1 (ko) *	2008-12-12	2010-12-17	한미약품 주식회사	(ｒ)-(+)-란소프라졸의 제조방법 및 이에 사용되는 중간체
WO2011004387A2 (en)	2009-06-18	2011-01-13	Matrix Laboratories Ltd	Process for the preparation of dexlansoprazole polymorphic forms
WO2011058569A1 (en)	2009-11-12	2011-05-19	Hetero Research Foundation	Process for the resolution of omeprazole
WO2011092665A1 (en)	2010-01-29	2011-08-04	Ranbaxy Laboratories Limited	Process for the preparation of crystalline forms of dexlansoprazole
JP6574773B2 (ja) *	2014-07-30	2019-09-11	株式会社アエタスファルマ	１，４−ベンゾチアゼピン−１−オキシド誘導体の光学異性体、及びそれを用いた医薬組成物
ES2615637T3 (es)	2015-03-06	2017-06-07	F.I.S.- Fabbrica Italiana Sintetici S.P.A.	Procedimiento mejorado para la purificación óptica del esomeprazol

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1996
- 1996-05-21 HR HRPCT/SE95/00817A patent/HRP960232A2/hr not_active Application Discontinuation
- 1996-06-19 SA SA96170103A patent/SA96170103B1/ar unknown
- 1996-06-19 RS YUP-376/96A patent/RS49826B/sr unknown
- 1996-06-19 ZA ZA965205A patent/ZA965205B/xx unknown
- 1996-06-22 TW TW085107517A patent/TW444010B/zh not_active IP Right Cessation
- 1996-06-26 PT PT96922339T patent/PT836601E/pt unknown
- 1996-06-26 AT AT96922339T patent/ATE418549T1/de active
- 1996-06-26 CA CA002226184A patent/CA2226184C/en not_active Expired - Lifetime
- 1996-06-26 PL PL96324394A patent/PL186702B1/pl not_active IP Right Cessation
- 1996-06-26 NZ NZ311842A patent/NZ311842A/xx not_active IP Right Cessation
- 1996-06-26 WO PCT/SE1996/000841 patent/WO1997002261A1/en not_active Ceased
- 1996-06-26 UA UA97126300A patent/UA49838C2/uk unknown
- 1996-06-26 IL IL12281196A patent/IL122811A/xx not_active IP Right Cessation
- 1996-06-26 JP JP50506397A patent/JP4195507B2/ja not_active Expired - Lifetime
- 1996-06-26 ES ES96922339T patent/ES2318850T3/es not_active Expired - Lifetime
- 1996-06-26 EP EP96922339A patent/EP0836601B1/en not_active Expired - Lifetime
- 1996-06-26 HU HU9901717A patent/HUP9901717A3/hu not_active Application Discontinuation
- 1996-06-26 DZ DZ960101A patent/DZ2057A1/fr active
- 1996-06-26 CZ CZ19974211A patent/CZ295430B6/cs not_active IP Right Cessation
- 1996-06-26 BR BR9609450A patent/BR9609450A/pt not_active Application Discontinuation
- 1996-06-26 EE EE9700368A patent/EE03444B1/xx not_active IP Right Cessation
- 1996-06-26 CN CN96196465A patent/CN1098261C/zh not_active Expired - Lifetime
- 1996-06-26 KR KR1019970709953A patent/KR100451078B1/ko not_active Expired - Fee Related
- 1996-06-26 SI SI9630766T patent/SI0836601T1/sl unknown
- 1996-06-26 DK DK96922339T patent/DK0836601T3/da active
- 1996-06-26 RU RU98101727A patent/RU2144031C1/ru not_active IP Right Cessation
- 1996-06-26 DE DE69637788T patent/DE69637788D1/de not_active Expired - Lifetime
- 1996-06-26 US US08/676,215 patent/US5929244A/en not_active Expired - Lifetime
- 1996-06-26 SK SK1793-97A patent/SK284780B6/sk not_active IP Right Cessation
- 1996-06-26 TR TR97/01754T patent/TR199701754T1/xx unknown
- 1996-06-26 EP EP04024339A patent/EP1498416A1/en not_active Withdrawn
- 1996-06-26 AU AU63240/96A patent/AU698638B2/en not_active Expired
- 1996-06-28 MA MA24295A patent/MA23921A1/fr unknown
- 1996-07-02 TN TNPCT/SE1995/000817A patent/TNSN96090A1/fr unknown
- 1996-07-03 MY MYPI96002734A patent/MY114018A/en unknown
1997
- 1997-01-21 IS IS4638A patent/IS2666B/is unknown
- 1997-12-22 NO NO19976030A patent/NO313008B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
JP4195507B2 (ja)	2008-12-10
SK284780B6 (sk)	2005-11-03
AU698638B2 (en)	1998-11-05
NO313008B1 (no)	2002-07-29
PL186702B1 (pl)	2004-02-27
AU6324096A (en)	1997-02-05
TR199701754T1 (xx)	1998-04-21
EP0836601A1 (en)	1998-04-22
RS49826B (sr)	2008-08-07
SK179397A3 (en)	1998-09-09
JPH11508590A (ja)	1999-07-27
TW444010B (en)	2001-07-01
EP1498416A1 (en)	2005-01-19
DE69637788D1 (de)	2009-02-05
US5929244A (en)	1999-07-27
CZ295430B6 (cs)	2005-08-17
PT836601E (pt)	2009-02-17
UA49838C2 (uk)	2002-10-15
ES2318850T3 (es)	2009-05-01
YU37696A (sh)	1999-03-04
CA2226184A1 (en)	1997-01-23
HUP9901717A2 (hu)	2000-04-28
KR100451078B1 (ko)	2004-11-16
IL122811A (en)	2000-11-21
IL122811A0 (en)	1998-08-16
ATE418549T1 (de)	2009-01-15
IS2666B (is)	2010-08-15
NO976030L (no)	1998-02-09
BR9609450A (pt)	1999-03-02
MA23921A1 (fr)	1996-12-31
MX9800160A (es)	1998-03-31
PL324394A1 (en)	1998-05-25
CN1193971A (zh)	1998-09-23
EE03444B1 (et)	2001-06-15
HK1010193A1 (zh)	1999-06-17
EP0836601B1 (en)	2008-12-24
ZA965205B (en)	1997-01-03
CA2226184C (en)	2008-08-05
HUP9901717A3 (en)	2002-03-28
CN1098261C (zh)	2003-01-08
KR19990028631A (ko)	1999-04-15
RU2144031C1 (ru)	2000-01-10
TNSN96090A1 (fr)	2005-03-15
EE9700368A (et)	1998-06-15
HRP960232A2 (en)	1998-02-28
IS4638A (is)	1997-12-22
MY114018A (en)	2002-07-31
WO1997002261A1 (en)	1997-01-23
NO976030D0 (no)	1997-12-22
SI0836601T1 (sl)	2009-04-30
NZ311842A (en)	1998-12-23
CZ421197A3 (cs)	1998-06-17
SA96170103B1 (ar)	2006-07-30
DZ2057A1 (fr)	2002-10-20

Publication	Publication Date	Title
DK0836601T3 (da)	2009-03-16	Fremgangsmåde til optisk oprensning af enantiomert beriget benzimidasolderivater
DK0893434T3 (da)	2003-05-26	Mellemprodukter til fremstilling af oximethere
EP0814956A4 (en)	1998-12-30	MANUFACTURE OF OPTICAL ELEMENTS
DK1002534T3 (da)	2006-01-23	Anvendelse af fire K-252a-derivater
NO970212D0 (no)	1997-01-17	Fremgangsmåte for fremstilling av enantiomerene av O-demetyltramadol
DE69423179D1 (de)	2000-04-06	Prozess zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten
EP0663699A3 (en)	1995-09-27	Method for manufacturing an optoelectric semiconductor device.
DE69200868D1 (de)	1995-01-26	Verfahren zur Herstellung optischer Elemente.
DK0768310T3 (da)	2000-04-17	Fremgangsmåde til fremstilling af imidazo-benzodiazepin-derivater
DK0877738T3 (da)	2003-09-08	Fremgangsmåde til fremstilling af phenylimidazolidinderivater
DK0785949T3 (da)	2003-08-18	Fremgangsmåde til oprensning af keratinocytvækstfaktorer
DK0805806T3 (da)	2000-05-01	Fremgangsmåde til fremstilling af 4,10-diacetoxy-2alpha-benzoyloxy-5beta,20-epoxy-1,7beta-dihydroxy-9-oxotax-11-en-13alpha-
DE69113327D1 (de)	1995-11-02	Verfahren zur Herstellung optischer Elemente.
IS4636A (is)	1997-12-19	Aðferð við framleiðslu á hreinum enantíómerum af asetidín-2-karboxýlsýru
NO990450D0 (no)	1999-01-29	Behandling av sinnslidelser
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