DK0842947T3 - Hepatitis C-virus-asialoglycoproteiner - Google Patents

Hepatitis C-virus-asialoglycoproteiner

Info

Publication number: DK0842947T3
Authority: DK; Denmark
Prior art keywords: virus; proteins; hepatitis; hcv; recombinant
Prior art date: 1990-11-08

Application number

DK97120661T

Other languages

English (en)

Other versions

DK0842947T4 (da

Inventor

Robert O Ralston

Frank Marcus

Kent B Thudium

Barbara A Gervase

John A Hall

Original Assignee

Chiron Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-11-08

Filing date

1991-11-07

Publication date

2004-07-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27417050&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0842947(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1991-11-07 Application filed by Chiron Corp filed Critical Chiron Corp

2004-07-26 Publication of DK0842947T3 publication Critical patent/DK0842947T3/da

2009-06-08 Application granted granted Critical

2009-06-08 Publication of DK0842947T4 publication Critical patent/DK0842947T4/da

Links

241000711549 Hepacivirus C Species 0.000 title abstract 2
108010002913 Asialoglycoproteins Proteins 0.000 title 1
102000005427 Asialoglycoprotein Receptor Human genes 0.000 abstract 1
241000206602 Eukaryota Species 0.000 abstract 1
108090000288 Glycoproteins Proteins 0.000 abstract 1
102000003886 Glycoproteins Human genes 0.000 abstract 1
101710125507 Integrase/recombinase Proteins 0.000 abstract 1
108090001090 Lectins Proteins 0.000 abstract 1
102000004856 Lectins Human genes 0.000 abstract 1
108010031099 Mannose Receptor Proteins 0.000 abstract 1
101710185720 Putative ethidium bromide resistance protein Proteins 0.000 abstract 1
102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
108010003533 Viral Envelope Proteins Proteins 0.000 abstract 1
241000700605 Viruses Species 0.000 abstract 1
108010006523 asialoglycoprotein receptor Proteins 0.000 abstract 1
210000004027 cell Anatomy 0.000 abstract 1
238000012258 culturing Methods 0.000 abstract 1
239000002523 lectin Substances 0.000 abstract 1
210000004962 mammalian cell Anatomy 0.000 abstract 1
239000002245 particle Substances 0.000 abstract 1
230000027380 protein glycosylation in Golgi Effects 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
238000003259 recombinant expression Methods 0.000 abstract 1
230000009450 sialylation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Virology (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

DK97120661T 1990-11-08 1991-11-07 Hepatitis C-virus-asialoglycoproteiner DK0842947T4 (da)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US61196590A	1990-11-08	1990-11-08
US61141990A	1990-11-08	1990-11-08
US75888091A	1991-09-13	1991-09-13
PCT/US1991/008272 WO1992008734A1 (en)	1990-11-08	1991-11-07	Hepatitis c virus asialoglycoproteins
EP92900091A EP0556292B2 (en)	1990-11-08	1991-11-07	Hepatitis c virus asialoglycoproteins

Publications (2)

Publication Number	Publication Date
DK0842947T3 true DK0842947T3 (da)	2004-07-26
DK0842947T4 DK0842947T4 (da)	2009-06-08

Family

ID=27417050

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK97120661T DK0842947T4 (da)	1990-11-08	1991-11-07	Hepatitis C-virus-asialoglycoproteiner
DK92900091T DK0556292T4 (da)	1990-11-08	1991-11-07	Hepatitis C virus asialoglycoproteiner

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK92900091T DK0556292T4 (da)	1990-11-08	1991-11-07	Hepatitis C virus asialoglycoproteiner

Country Status (17)

Country	Link
EP (2)	EP0842947B2 (da)
JP (8)	JPH06504431A (da)
AT (1)	ATE188220T1 (da)
AU (1)	AU668078B2 (da)
CA (2)	CA2203443C (da)
CZ (1)	CZ289006B6 (da)
DE (1)	DE69131882T3 (da)
DK (2)	DK0842947T4 (da)
ES (1)	ES2139591T5 (da)
FI (1)	FI107803B (da)
GR (1)	GR3032771T3 (da)
HU (2)	HUT66063A (da)
NO (2)	NO304380B1 (da)
PT (2)	PT99466B (da)
RO (1)	RO115446B1 (da)
SK (3)	SK286106B6 (da)
WO (1)	WO1992008734A1 (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6274148B1 (en) *	1990-11-08	2001-08-14	Chiron Corporation	Hepatitis C virus asialoglycoproteins
JP3158177B2 (ja) *	1991-10-08	2001-04-23	国立感染症研究所長	Ｃ型肝炎診断薬
JP3439209B2 (ja) *	1992-01-31	2003-08-25	アボツト・ラボラトリーズ	Ｈｃｖ蛋白のための哺乳動物発現システム
UA39944C2 (uk) *	1992-07-07	2001-07-16	Чірон Корпорейшн	Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі
WO1994026306A1 (en) *	1993-05-12	1994-11-24	Chiron Corporation	Conserved motif of hepatitis c virus e2/ns1 region
US5514539A (en) *	1993-06-29	1996-05-07	The United States Of America As Represented By The Department Of Health And Human Services	Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US5610009A (en) *	1994-01-28	1997-03-11	Abbott Laboratories	Mammalian expression systems for hepatitis C virus envelope genes
AU3241095A (en) *	1994-07-29	1996-03-04	Chiron Corporation	Novel hepatitis c e1 and e2 truncated polypeptides and methods of obtaining the same
ES2174957T5 (es)	1994-07-29	2006-12-16	Innogenetics N.V.	Proteinas purificadas de envoltura de virus de la hepatitis c para uso diagnostico y terapeutico.
DE69534296T2 (de)	1994-07-29	2006-04-27	Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville	Sezernierter E1/E2-Komplex des Hepatitis C-Virus, des aus C-terminal verkürzten Polypeptiden E1 und E2 erhalten ist
IT1271593B (it) *	1994-11-30	1997-06-04	Sanitaria Scaligera Spa	Procedimento ed apparecchiatura per l'immunoadsorbimento specifico di virus hiv, di antigene gp120 e complesso cd4-gp120.
US6127116A (en)	1995-08-29	2000-10-03	Washington University	Functional DNA clone for hepatitis C virus (HCV) and uses thereof
FR2744725B1 (fr) *	1996-02-09	1998-04-30	Pasteur Institut	Anticorps specifiques des complexes formes par les glycoproteines e1 et e2 du virus de l'hepatite c, procedes de determination de la presence, et d'isolement de ces complexes
US6514731B1 (en)	1996-05-24	2003-02-04	Chiron Corporation	Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens
KR100209095B1 (ko)	1996-06-28	1999-07-15	성재갑	C형 간염 바이러스의 프로테아제의 활성을 측정할 수 있는 c형 간염 대체 바이러스, 그 재조합 유전자 및 그 용도
CA2269097C (en)	1996-11-08	2007-01-09	The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services	Synthesis and purification of hepatitis c virus-like particles
US7049428B1 (en)	1998-03-04	2006-05-23	Washington University	HCV variants
US7338759B1 (en)	1997-03-04	2008-03-04	Washington University	HCV variants
DE69841015D1 (de)	1997-05-06	2009-09-10	Novartis Vaccines & Diagnostic	Intrazelluläre herstellung von verkürztem hepatitis c-polypeptid e2
EP0947525A1 (en)	1998-03-27	1999-10-06	Innogenetics N.V.	Epitopes in viral envelope proteins and specific antibodies directed against these epitopes: use for detection of HCV viral antigen in host tissue
US7108855B2 (en)	1998-06-24	2006-09-19	Innogenetics N.V.	Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use
US6858590B2 (en)	2000-08-17	2005-02-22	Tripep Ab	Vaccines containing ribavirin and methods of use thereof
US7022830B2 (en)	2000-08-17	2006-04-04	Tripep Ab	Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
JP5175417B2 (ja)	2000-08-17	2013-04-03	トリペップアクチボラゲット	リバビリンを含むワクチンおよびその使用方法
US6680059B2 (en)	2000-08-29	2004-01-20	Tripep Ab	Vaccines containing ribavirin and methods of use thereof
US7101561B2 (en)	2000-12-01	2006-09-05	Innogenetics N.V.	Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use
US20030232745A1 (en) *	2001-06-26	2003-12-18	Olson William C.	Uses of DC-sign and DC-Signr for inhibiting hepatitis C virus infection
US7022323B2 (en)	2001-06-26	2006-04-04	Progenics Pharmaceuticals, Inc.	Uses of DC-SIGN and DC-SIGNR for inhibiting hepatitis C virus infection
EP1551960A4 (en) *	2002-08-16	2006-02-01	Univ Ohio	CLEANING HEPATITIS C VIRUS SIMILAR PARTICLE
CA2618429A1 (en)	2005-05-25	2007-03-22	Tripep Ab	A hepatitis c virus non-structural ns3/4a fusion gene
US8071561B2 (en)	2007-08-16	2011-12-06	Chrontech Pharma Ab	Immunogen platform
US20090214593A1 (en)	2007-08-16	2009-08-27	Tripep Ab	Immunogen platform

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH02500880A (ja) *	1987-11-18	1990-03-29	カイロン　コーポレイション	Ｎａｎｂｖの診断用薬およびワクチン
IL88599A0 (en) *	1987-12-10	1989-07-31	Cell Bio Group Ltd	Glycoprotein cell growth modulating materials,their preparation and compositions containing them
KR0185373B1 (ko) *	1989-03-17	1999-05-01	로버트 피. 블랙버언	Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
HU217025B (hu) *	1990-04-04	1999-11-29	Chiron Corp.	Hepatitis C vírus-(HCV) antigénkészítmények az anti-HCV-antitestek kimutatására immunoassay-kben

1991
- 1991-11-07 SK SK40-2005A patent/SK286106B6/sk unknown
- 1991-11-07 DK DK97120661T patent/DK0842947T4/da active
- 1991-11-07 JP JP4500944A patent/JPH06504431A/ja active Granted
- 1991-11-07 SK SK690-97A patent/SK285624B6/sk not_active IP Right Cessation
- 1991-11-07 AT AT92900091T patent/ATE188220T1/de not_active IP Right Cessation
- 1991-11-07 EP EP97120661A patent/EP0842947B2/en not_active Expired - Lifetime
- 1991-11-07 EP EP92900091A patent/EP0556292B2/en not_active Expired - Lifetime
- 1991-11-07 HU HU9301336A patent/HUT66063A/hu unknown
- 1991-11-07 DK DK92900091T patent/DK0556292T4/da active
- 1991-11-07 CA CA002203443A patent/CA2203443C/en not_active Expired - Lifetime
- 1991-11-07 HU HU9301336A patent/HU227498B1/hu unknown
- 1991-11-07 ES ES92900091T patent/ES2139591T5/es not_active Expired - Lifetime
- 1991-11-07 WO PCT/US1991/008272 patent/WO1992008734A1/en not_active Ceased
- 1991-11-07 RO RO93-00626A patent/RO115446B1/ro unknown
- 1991-11-07 AU AU90267/91A patent/AU668078B2/en not_active Expired
- 1991-11-07 CZ CZ1993824A patent/CZ289006B6/cs not_active IP Right Cessation
- 1991-11-07 DE DE69131882T patent/DE69131882T3/de not_active Expired - Lifetime
- 1991-11-07 SK SK442-93A patent/SK285623B6/sk not_active IP Right Cessation
- 1991-11-07 CA CA002095521A patent/CA2095521C/en not_active Expired - Lifetime
- 1991-11-08 PT PT99466A patent/PT99466B/pt not_active IP Right Cessation
1993
- 1993-05-05 FI FI932025A patent/FI107803B/fi not_active IP Right Cessation
- 1993-05-07 NO NO931680A patent/NO304380B1/no not_active IP Right Cessation
1997
- 1997-05-14 NO NO972213A patent/NO304381B1/no not_active IP Right Cessation
- 1997-06-26 PT PT102022A patent/PT102022B/pt not_active IP Right Cessation
1998
- 1998-04-14 JP JP10317898A patent/JP3207155B2/ja not_active Expired - Lifetime
2000
- 2000-02-28 GR GR20000400473T patent/GR3032771T3/el unknown
2001
- 2001-03-02 JP JP2001059335A patent/JP2001286290A/ja not_active Withdrawn
2002
- 2002-07-08 JP JP2002199317A patent/JP4056306B2/ja not_active Expired - Lifetime
- 2002-12-04 JP JP2002353148A patent/JP2003174875A/ja not_active Withdrawn
2005
- 2005-02-10 JP JP2005035317A patent/JP2005187479A/ja not_active Withdrawn
2006
- 2006-05-25 JP JP2006145982A patent/JP2006219503A/ja not_active Withdrawn
2007
- 2007-10-12 JP JP2007267258A patent/JP2008031181A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
DE69131882T2 (de)	2000-05-04
SK285623B6 (sk)	2007-05-03
NO931680L (no)	1993-06-28
PT102022A (pt)	1999-01-29
WO1992008734A1 (en)	1992-05-29
AU9026791A (en)	1992-06-11
PT99466A (pt)	1992-10-30
CA2203443C (en)	2001-08-28
EP0556292A4 (da)	1995-01-18
CA2095521C (en)	2009-06-30
GR3032771T3 (en)	2000-06-30
EP0842947B2 (en)	2009-03-18
EP0842947A2 (en)	1998-05-20
RO115446B1 (ro)	2000-02-28
PT102022B (pt)	2000-12-29
NO304380B1 (no)	1998-12-07
NO304381B1 (no)	1998-12-07
EP0842947B1 (en)	2004-04-21
FI107803B (fi)	2001-10-15
PT99466B (pt)	1999-04-30
JP3207155B2 (ja)	2001-09-10
JP2003093081A (ja)	2003-04-02
EP0556292B1 (en)	1999-12-29
ES2139591T5 (es)	2007-08-01
FI932025A0 (fi)	1993-05-05
JPH06504431A (ja)	1994-05-26
CA2203443A1 (en)	1992-05-09
CA2095521A1 (en)	1992-05-09
DE69131882D1 (en)	2000-02-03
ES2139591T3 (es)	2000-02-16
JP2006219503A (ja)	2006-08-24
SK69097A3 (en)	1997-11-05
JP2001286290A (ja)	2001-10-16
EP0842947A3 (en)	2001-12-12
DK0556292T3 (da)	2000-04-17
FI932025L (fi)	1993-06-07
JP2005187479A (ja)	2005-07-14
JP2008031181A (ja)	2008-02-14
JP2003174875A (ja)	2003-06-24
HU227498B1 (en)	2011-07-28
NO931680D0 (no)	1993-05-07
SK286106B6 (sk)	2008-03-05
SK285624B6 (sk)	2007-05-03
JPH1171395A (ja)	1999-03-16
DE69131882T3 (de)	2007-05-24
ATE188220T1 (de)	2000-01-15
CZ82493A3 (en)	1994-04-13
SK44293A3 (en)	1993-08-11
HUT66063A (en)	1994-09-28
CZ289006B6 (cs)	2001-10-17
HU9301336D0 (en)	1993-10-28
DK0556292T4 (da)	2006-12-27
AU668078B2 (en)	1996-04-26
NO972213D0 (no)	1997-05-14
EP0556292A1 (en)	1993-08-25
NO972213L (no)	1997-05-14
DK0842947T4 (da)	2009-06-08
EP0556292B2 (en)	2006-11-29
JP4056306B2 (ja)	2008-03-05

Publication	Publication Date	Title
DK0556292T3 (da)	2000-04-17	Hepatitis C virus asialoglycoproteiner
ATE229543T1 (de)	2002-12-15	Polypeptide des hepatitis c-virus (hiv)
PT989999E (pt)	2005-01-31	Composicao anti-tumoral a base de polipeptido imunogenico de localizacao celular modificada
FI941199A0 (fi)	1994-03-14	Immunoreaktiiviset hepatiitti-C-viruksen polypeptidikoostumukset
ATE423204T1 (de)	2009-03-15	Herstellung und reinigung von hepatitis c virus- ähnlichen partikeln
DE69535018D1 (de)	2006-07-06	Papillomavirus vakzine
CA2056437A1 (en)	1990-12-30	Production of virus and purification of viral envelope proteins for vaccine use
AU7234987A (en)	1987-11-09	Viral vector coding for a glycoprotein of the virus responsible for a.i.d.s., vaccine and antibody
FR2445338A1 (fr)	1980-07-25	Preparation de glycoproteine isolee d'enveloppes d'onco-rna virus et vaccins qui la contiennent
EP0216564A3 (en)	1988-08-10	Infectious recombinant virus, vaccines containing said virus for feline leukemia, and methods for the production thereof
PT586076E (pt)	2003-11-28	Vacinas de adenovirus recombinantes
RU93043621A (ru)	1997-02-10	Способы получения гликопротеинов нсv, способ очистки, аналитический набор, способ выявления нсv, способ элиминации нсv, способ индукции иммунитета, гликопротеины, иммунореагенты
EP1471073A3 (en)	2004-12-01	Hepatitis C virus asialoglycoproteins
FI971702L (fi)	1997-04-21	Hepatiitti-C-viruksen asialoglykoproteiinit
KR880003971A (ko)	1988-05-31	재조합 바쿨로비루스 벡터로 부터 b형 간염비루스 항원의 발현
KR890701745A (ko)	1989-12-21	O-결합 글리코실화가 감소된 바이러스 단백질
EP0385394A3 (en)	1991-05-22	Polyhedrin gene and genetic engineering thereof
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